scholarly journals The bowel and beyond: extracolonic findings from CT colonography

Author(s):  
Gerard Lambe ◽  
Peter Hughes ◽  
Louise Rice ◽  
Caoimhe McDonnell ◽  
Mark Murphy ◽  
...  

AbstractCT colonography has emerged as the investigation of choice for suspected colorectal cancer in patients when a colonoscopy in incomplete, is deemed high risk or is declined because of patient preference. Unlike a traditional colonoscopy, it frequently reveals extracolonic as well as colonic findings. Our study aimed to determine the prevalence, characteristics and potential significance of extracolonic findings on CT colonography within our own institution. A retrospective review was performed of 502 patients who underwent CT colonography in our institution between January 1, 2010 and January 4, 2015. Of 502 patients, 60.63% had at least one extracolonic finding. This was close to other similar-sized studies (Kumar et al. Radiology 236(2):519–526, 2005). However, our rate of E4 findings was significantly higher than that reported in larger studies at 5.3%(Pooler et al. AJR 206:313–318, 2016). The difference may be explained by our combination of symptomatic/screening patients or by the age and gender distribution of our population. Our study lends support to the hypothesis that CT colonography may be particularly useful in identifying clinically significant extracolonic findings in symptomatic patients. CT colonography may allow early identification of extracolonic malignancies and life-threatening conditions such as an abdominal aortic aneurysm at a preclinical stage when they are amenable to medical or surgical intervention. However, extracolonic findings may also result in unnecessary investigations for subsequently benign findings.

2019 ◽  
pp. 43-70
Author(s):  
Sukhjit Dhillon ◽  
James McCue ◽  
Steven Riccoboni ◽  
Caleb Sunde

Gastrointestinal disorders and emergencies are one of the most common presentations to an emergency department (ED). Symptoms frequently seen in the ED include abdominal pain, nausea, vomiting, diarrhea, and fever. The differential diagnosis changes depending on the age and gender of the patient, duration of symptoms, the systemic effects, recent travel or exposures, and the description of the symptoms. Life-threatening emergencies include abdominal aortic aneurysm, mesenteric ischemia, foreign body ingestion, gastrointestinal bleeding, acute pancreatitis, spontaneous bacterial peritonitis, aortoenteric fistula, and acute bilirubin encephalopathy, among others. It is the emergency physician’s job to recognize these life-threatening conditions of the gastrointestinal tract and start treatment.


Author(s):  
Alberto Portera ◽  
Marco Bassani

Current design manuals provide guidance on how to design exit ramps to facilitate driving operations and minimize the incidence of crashes. They also suggest that interchanges should be built along straight roadway sections. These criteria may prove ineffective in situations where there is no alternative to terminals being located along curved motorway segments. The paper investigates driving behavior along parallel deceleration curved terminals, with attention paid to the difference in impact between terminals having a curvature which is the same sign as the motorway segment (i.e., continue design), and those having an opposite curvature (i.e., reverse design). A driving simulation study was set up to collect longitudinal and transversal driver behavioral data in response to experimental factor variations. Forty-eight drivers were stratified on the basis of age and gender, and asked to drive along three randomly assigned circuits with off-ramps obtained by combining experimental factors such as motorway mainline curve radius (2 values), terminal length (3), curve direction (2), and traffic conditions (2). The motorway radius was found to be significant for drivers’ preferred speed when approaching the terminal. Terminal length and traffic volume do not have a significant impact on either longitudinal or transversal driver outputs. However, the effect of curve direction was found to be significant, notably for reverse terminals which do not compel drivers to select appropriate speeds and lane change positions. This terminal type can give rise to critical driving situations that should be considered at the design stage to facilitate the adoption of appropriate safety countermeasures.


2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Yong Woo Lee ◽  
Joon Mo Kim ◽  
Seong Hee Shim ◽  
Da Yeong Kim ◽  
Jeong Hun Bae ◽  
...  

Purpose. To evaluate the diurnal intraocular pressure (IOP) in eyes after vitrectomy compared to that of healthy eyes.Methods. Twenty-one patients who had undergone vitrectomy and 21 age- and gender-matched normal controls were enrolled during the same period. We measured the diurnal IOP every two hours between 9 a.m. and 11 p.m. in all patients who were admitted for cataract surgery. Patients with a history of eye surgery (not including vitrectomy) or use of a medication that is associated with IOP were excluded. The IOP and ocular parameters of patients were compared with the same patients’ fellow healthy eyes and with normal eyes of age- and gender-matched controls.Results. There were no significant differences between vitrectomized eyes and normal fellow eyes with regard to all IOP parameters including the maximum, minimum, and IOP fluctuation values. Diurnal fluctuation of IOP (or the difference between the maximum and minimum IOP) was larger in vitrectomized eyes than it was in age- and gender-matched control eyes.Conclusions. Vitrectomy did not markedly affect the IOP. Although there were no severe complications after vitrectomy, the IOP fluctuation was wider in vitrectomized eyes than it was in normal eyes.


1981 ◽  
Vol 13 (3) ◽  
pp. 183-193 ◽  
Author(s):  
Pamela E. Cooper ◽  
L. Eugene Thomas ◽  
Scott J. Stevens ◽  
David Suscovich

The roles chronological age and gender play in subjective time experience were explored in a sample of 294 adult men and women. Subjective time experience (STE: the difference between subjective age and chronological age) was found to vary widely among individuals, with some being “accurate” (SA = CA), and others either “retarded” (SA < CA) or “advanced” (SA > CA). Males were more retarded in STE than females at every point in the lifespan, and patterns of age differences in adulthood differed for the two sexes as well. The results suggest that chronological age may play a key role in transitions in STE, and that chronological age is more significant in the STE of women than in the STE of men.


2014 ◽  
Vol 18 (6) ◽  
pp. 968-976 ◽  
Author(s):  
Hadeil M Alsufiani ◽  
Fatmah Yamani ◽  
Taha A Kumosani ◽  
Dianne Ford ◽  
John C Mathers

AbstractObjectiveTo assess the relative validity and repeatability of a sixty-four-item FFQ for estimating dietary intake of Zn and its absorption modifiers in Saudi adults. In addition, we used the FFQ to investigate the effect of age and gender on these intakes.DesignTo assess validity, all participants completed the FFQ (FFQ1) and a 3 d food record. After 1 month, the FFQ was administered for a second time (FFQ2) to assess repeatability.SettingJeddah, Saudi Arabia.SubjectsOne hundred males and females aged 20–30 years and 60–70 years participated.ResultsMean intakes of Zn and protein from FFQ1 were significantly higher than those from the food record while there were no detectable differences between tools for measurement of phytic acid intake. Estimated intakes of Zn, protein and phytate by both approaches were strongly correlated (P<0·001). Bland–Altman analysis showed for protein that the difference in intake as measured by the two methods was similar across the range of intakes while for Zn and phytic acid, the difference increased with increasing mean intake. Zn and protein intakes from FFQ1 and FFQ2 were highly correlated (r>0·68,P<0·001) but were significantly lower at the second measurement (FFQ2). Older adults consumed less Zn and protein compared with young adults. Intakes of all dietary components were lower in females than in males.ConclusionsThe FFQ developed and tested in the current study demonstrated reasonable relative validity and high repeatability and was capable of detecting differences in intakes between age and gender groups.


2020 ◽  
Vol 11 (SPL3) ◽  
pp. 441-446
Author(s):  
Nur Liyana Hannah Binti Izham Akmal ◽  
Adimulapu Hima Sandeep ◽  
Revathi Duraisamy

Cervical lesions are often characterized by defects seen in the gingival third of a tooth crown which may be in the facial or lingual surface. Pathological loss of tooth structure caused by factors other than dental caries such as cervical abrasion is referred to as non-carious cervical lesions (NCCL). Cervical abrasion is an example of NCCL in which a constant exposure of the tooth to mechanical forces leads to pathological wearing away of the hard tissues. In most of the cases, cervical tooth lesions are revealed to be more common as the age increases. Several studies have reported the difference in the prevalence of cervical abrasion between males and females. Many reports suggest that cervical abrasion is commonly associated with improper tooth brushing habits. To evaluate the prevalence of cervical abrasion between genders and its influence on age. It is a retrospective study conducted using the case records of Saveetha Dental College and Hospital, Chennai, India from June 2019 to March 2020. Data including the patient’s name, patient’s identification number (PID), age, gender and presence of cervical abrasion were retrieved from the patients’ case records. A total of 742 consecutive case records were retrieved and analysed. Cervical abrasion was observed in 371 individuals of this study. High prevalence of cervical abrasions was seen in males (70.9%) compared to females (29.1%). Most of the cases were observed in individuals within the 41-50 years age group (28.8%), and the least was seen within the 11-20 years age group (0.3%). Within the limits of the study, most of the cervical abrasion cases are recorded in individuals within the 41-50 years age group with higher predilection in males. There is a statistically significant association of cervical abrasion with age and gender.


2021 ◽  
Vol 2 (2) ◽  
pp. 1-8
Author(s):  
Agniva Pal ◽  

This is a neuro-linguistic research which compares Bangla speaking right hemisphere damaged (furthermore to be called RHD) male participants to age and gender matched normal males who have been selected from the same family as the right hemisphere damaged participants. RHD or right hemisphere damaged participants are those who have lesions or damages in the right hemisphere of the brain or both. This paper pertains to the understanding how a lesion or a damage in the right hemisphere can cause changes in the pattern of communication of adult males in the age group of 45 to 70. This paper discerns the difference in durations of controlled speech in RHD males compared to age and gender matched normal controls. It will be measured with the help a predetermined passage. A passage will be played to them, using a media player (to make sure everyone listens to the same recording, ruling out chances of error there) and then they will be asked to repeat the same passage, as much as they can remember. In this research, we will be looking at the time they would take to narrate the whole passage without missing out on anything.


2020 ◽  
Author(s):  
Shao Ju ◽  
Shaosong Zhou ◽  
Yuan Qu ◽  
bibo liang ◽  
Qing-Hong Yu ◽  
...  

Abstract Background: Bone turnover and metabolic indicators are related to age and gender. Age and gender should be matched in subjects in disease control research of bone turnover and metabolism, but strict matching of gender and age increases the difficulty and cost of the research. Therefore, the aim of this study was to solve the question of whether it is necessary to strictly match age and gender in clinical research in bone metabolism.METHODS: Patient data were extracted from the HIS of ZhuJiang Hospital, Southern Medical University. From these data, a cross-sectional study was conducted. Data relating to seven bone turnover and metabolic indicators from 1036 patients between January 2018 and October 2019 were analyzed. A total of 156 patients aged under 20 were identified and analyzed separately. RESULTS: P1NP, β-CTx and 25(OH)D were significant different in individuals younger than 20 years of age. ALP was significantly higher in those under 20 years of age and lower at age 20-39 compared with other age groups. The concentrations of Ca and P were different among the groups aged 0-19, 20-39, and 40-59 years of age groups but exhibited no difference above 60 years of age. PTH expression was not dependent on age. P1NP, β-CTx and PTH concentrations were not significantly different between the genders within the same age group. ALP was significantly different between genders within the age range 20-59 years. Ca and 25(OH)D were significantly different between the genders for those older than 60. Serum P was significantly different in the two genders for those aged 40-79. CONCLUSION: P1NP and β-CTx were highly correlated with age. If these two indictors require analysis in a case control study, the patients and controls should be strictly matched by age under 20 years. The demarcation point for ALP was 40 years of age. Ca and P were strongly recommended strict matching according to age in disease research. The difference in P1NP, β-CTx, 25(OH)D and ALP between genders depends on age differences.


2003 ◽  
Vol 94 (1) ◽  
pp. 259-270 ◽  
Author(s):  
Minoru Shinohara ◽  
Sheng Li ◽  
Ning Kang ◽  
Vladimir M. Zatsiorsky ◽  
Mark L. Latash

The objective of the study is to examine the effects of age and gender on finger coordination. Twelve young (24 ± 8 yr; 6 men and 6 women) and 12 elderly (75 ± 5 yr; 6 men and 6 women) subjects performed single-finger maximal contraction [maximal voluntary contraction (MVC)], four-finger MVC, and four-finger ramp force production tasks by pressing on individual force transducers. A drop in the force of individual fingers during four-finger MVC tasks compared with single-finger MVC tasks (force deficit) was larger, whereas unintended force production by other fingers during single-finger MVC tasks (enslaving) was smaller, in elderly than in young subjects and in women than in men. Force deficit was smaller and enslaving was larger in subjects with higher peak force. During the ramp task, the difference between the variance of total force and the sum of variances of individual forces showed a logarithmic relation to the level of total force, across all subject groups. These findings suggest that indexes of finger coordination scale with force-generating capabilities across gender and age groups.


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