Unchanged asymmetric dimethylarginine levels in non-diabetic, premenopausal obese women who have common risk factors for cardiovascular disease

Endocrine ◽  
2007 ◽  
Vol 31 (2) ◽  
pp. 100-104 ◽  
Author(s):  
P. Cetinalp-Demircan ◽  
A. Can ◽  
Selda Bekpinar ◽  
Y. Unlucerci ◽  
Y. Orhan
2005 ◽  
Vol 6 (3) ◽  
pp. 78-85 ◽  
Author(s):  
Amir Moeintaghavi ◽  
A. Haerian-Ardakani ◽  
Mohammadreza Talebi-Ardakani ◽  
I. Tabatabaie

Abstract Background Periodontitis is a bacterial infection, which has been classified as a local chronic inflammation. This, as well as cardiovascular disease, may share common risk factors such as smoking, diabetes, behavioral factors, aging, and male gender. The aim of this study was to evaluate the association between hyperlipidemia and periodontitis. Materials & Methods The levels of plasma lipids in 40 subjects with periodontitis (CPITN score III or IV, pocket depth 4 mm) with mean age 32.3 ±1.2 years were measured and compared with those obtained from 40 age and sex matched controls. Both groups were systemically healthy according to their medical history. Results Total cholesterol (CHL) and triglycerides (TG) were significantly higher in the case group (P=0.045 and P=0.016, respectively). HDL and LDL cholesterols were higher in patients but did not have any significant differences with controls. The frequency of persons with pathologic values of TG and CHL were significantly higher in cases compared with controls. Conclusions These results showed hyperlipidemia may be associated with periodontitis in healthy people. However, it is unclear whether periodontitis causes an increase in levels of serum lipids or hyperlipidemia is a risk factor for both periodontitis and cardiovascular disease. Citation Moeintaghavi A, Haerian-Ardakani A, Talebi-Ardakani M, Tabatabaie I. Hyperlipidemia in Patients with Periodontitis. J Contemp Dent Pract 2005 August;(6)3:078-085.


Author(s):  
Masuder Rahman ◽  
Sakila Akter ◽  
Fatama Tous Zohora ◽  
Abu Zaffar Shibly

Background: Cardiovascular Disease (CVD) is a major public health problem throughout the world. In Bangladesh, the reliable data concerning various aspects of CVD is inadequate at present due to lack of national population-based surveys or central administrative health data. Given the rising incidence of CVDs in Bangladesh, an improved understanding of the CVD, symptoms and risk factors is needed. Hence, this study was performed to assess the level of knowledge towards CVD types, warning symptoms of heart attack or stroke, and CVD risk factors.Methods: A descriptive cross-sectional survey was conducted from May 2018 to June 2018 using standard questionnaire on a sample of 350 randomly selected Bangladeshi individuals. All the data of the study were input in SPSS (Statistical Package for the Social Sciences) version 20.0 software from IBM for windows and the gathered data thus analyzed using SPSS & Microsoft Excel.Results: The respondents’ knowledge about types of CVD, symptom heart attack, symptom of stroke and the risk factors of CVD are 38.9%, 67.7%, 35.7%, and 92.9% respectively. The most common risk factors of CVD found to be known by around than two-third of respondents were unhealthy diet (66.9%), physical inactivity (64.3), obesity (61.4%), and smoking (58.6%).Conclusions: The respondents’ knowledge about types of CVD, symptom heart attack, symptom of stroke and the risk factors of CVD are 38.9%, 67.7%, 35.7%, and 92.9% respectively. The most common risk factors of CVD found to be known by around than two-third of respondents were unhealthy diet (66.9%), physical inactivity (64.3), obesity (61.4%), and smoking (58.6%).


2008 ◽  
Vol 02 (02) ◽  
pp. 142-149 ◽  
Author(s):  
Ozlem Fentoglu ◽  
F. Yesim Bozkurt

ABSTRACTIt has been proposed for several decades that infections may be responsible for the accelerated development of atherosclerosis. The initiation of the atherosclerotic plaque is ascribed to focal accumulation of lipids. This explains the importance of plasma lipids in the development of atherosclerosis. Recent reports point towards a possible association between periodontal disease and increased risk for cardiovascular disease. Thus, periodontitis and cardiovascular disease may share common risk factors, and association between periodontitis and coronary heart disease may be due to the elevated levels of plasma lipids. Epidemiological and clinical studies have also suggested that there is a relationship between periodontal disease and impaired lipid metabolism. In this review, we summarized the potential link mechanisms in the association between periodontal infection and serum lipids. (Eur J Dent 2008;2:142-149)


2019 ◽  
Vol 65 (1) ◽  
pp. 80-86 ◽  
Author(s):  
Ralph Stewart

Abstract BACKGROUND In aging populations, cardiovascular disease (CVD) and frailty are common and often coexist. It is possible that common risk factors and pathophysiological pathways increase the risk of both CVD and frailty. CONTENT Frailty is a complex clinical syndrome with multiple causes and contributing factors. It is characterized by multisystem impairment that decreases physiological reserve and increases vulnerability to stress. Diverse methods have been used to evaluate frailty. Most include 1 or several measures related to reduced exercise, physical function, cognition, activities of daily living, comorbidities, deficits and/or markers of physiological dysfunction. CVD and frailty may be linked by several mechanisms. CVD can accelerate frailty, and frailty increases the risk of adverse outcomes in patients with CVD. Common pathophysiological pathways are also important. Low physical activity, poor nutrition, diabetes, hypertension, and smoking may increase the risk of both CVD and frailty. Further research is needed to evaluate whether biomarkers of dysfunction across multiple body systems, which are known to be associated with aging, and with CV and non-CV morbidity and mortality, are also associated with frailty. SUMMARY Multiple pathophysiological pathways are associated with both CVD and frailty, which interact to further increase the risk of adverse outcomes.


2020 ◽  
Vol 27 (8) ◽  
pp. 2323-2339
Author(s):  
Sharan Srinivas ◽  
Kavin Anand ◽  
Anand Chockalingam

PurposeWhile cardiovascular disease (CVD) is the leading cause of death globally, over 80% of the cases could be prevented through early lifestyle changes. From the perspective of quality management in healthcare, this may offer an effective prevention window if modifiable CVD risk factors are identified and treated in adolescence. The purpose of this research is to examine the negative emotions in adolescents and determine if it independently increases CVD risk later in life.Design/methodology/approachLongitudinal data from 12,350 participants of the Add Health study, which conducted a multi-wave survey for 14 years from adolescence (Wave 1) through adulthood (Wave 4), were used to test the research hypothesis. Four items (perception of life, self-reported depression, perceived loneliness and fearfulness) reflective of adolescent negative emotion were identified from the Wave 1 questionnaire, and factor analysis was conducted to confirm the hypothesized structure. The outcome variable, 30-year adulthood CVD risk category (high or low risk), was estimated using biomarkers, biological data and other factors collected during the 14-year follow-up in Wave 4. A logistic regression analysis was employed to assess the impact of adolescent negative emotions on adulthood CVD risk after adjusting for common risk factors such as sociodemographic characteristics, socioeconomic status and medical conditions in adolescence.FindingsThe results indicated adolescent negative emotion to be significantly associated with CVD risk category (p-value < 0.0001), even after controlling for common risk factors. A unit increase in the level of adolescent negative emotion increased the chance of being in the high CVD risk group in adulthood by 8% (odds ratio = 1.08 ± 0.03).Practical implicationsHealthcare providers and organizations could capitalize on the research findings by screening for negative emotions early in life through individual and societal interventions. The findings also provide an opportunity for implementing quality improvement initiatives to deliver robust preventive care, which, in turn, could improve the overall population health, reduce healthcare costs and improve care quality.Originality/valueAlthough previous studies showed a strong link between adolescent physiological factors (e.g. obesity) and adulthood cardiovascular disease (CVD), the association between adolescent outlook/attitude (negative emotion) and CVD risk has not been examined.


1995 ◽  
Vol 3 (S5) ◽  
pp. 649S-653S ◽  
Author(s):  
Hiroaki Tanaka ◽  
Tetsuji Kakiyama ◽  
Kazuko Takahara ◽  
Miyoko Yamauchi ◽  
Mamoru Tanaka ◽  
...  

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