Inhibitory effect of Lactobacillus plantarum K-1 on passive cutaneous anaphylaxis reaction and scratching behavior in mice

2011 ◽  
Vol 34 (12) ◽  
pp. 2117-2123 ◽  
Author(s):  
Se-Eun Jang ◽  
Hien-Trung Trinh ◽  
Yong-Hyun Chung ◽  
Myung Joo Han ◽  
Dong-Hyun Kim
2007 ◽  
Vol 30 (6) ◽  
pp. 1153-1156 ◽  
Author(s):  
Bomi Lee ◽  
Eun-Ah Bae ◽  
Hien Trung Trinh ◽  
Yong-Wook Shin ◽  
Thien Thuong Phuong ◽  
...  

1972 ◽  
Vol 50 (3) ◽  
pp. 255-262 ◽  
Author(s):  
P. W. Wells ◽  
P. Eyre

The effects of mepyramine maleate, sodium meclofenamate, methysergide bimaleate, diethylcarbamazine citrate, and disodium cromoglycate on bovine cutaneous anaphylactic reactions and responses to intradermal injections of histamine, 5-hydroxytryptamine, and bradykinin were studied. Calves sensitized by immunization with horse serum in Freund's complete adjuvant were bled to obtain skin-sensitizing serum which was used in passive cutaneous anaphylaxis (P.C.A.) tests. A latent period of 72 h was allowed between intradermal injections of sera and antigen challenge. Mepyramine maleate (10 mg/kg) selectively inhibited responses to histamine and raised the threshold dose of antibody required to elicit a response. Disodium cromoglycate (DSCG, 10 mg/kg) given intravenously 30 min or immediately prior to challenge had no significant effect either on the responses to drugs or on the passive cutaneous anaphylaxis reaction. Diethylcarbamazine (DECC, 20 mg/kg) administered immediately prior to challenge significantly inhibited the cutaneous anaphylactic response and when DSCG was given simultaneously with DECC, this inhibitory effect was apparently augmented. Methysergide (1 mg/kg) and sodium meclofenamate (2 mg/kg) were ineffective in suppressing P.C.A. It is concluded that histamine and a slow-reacting substance (SRS-A) are involved in the mediation of bovine cutaneous anaphylaxis and that kinins may contribute, while 5-hydroxytryptamine would appear unimportant.


2011 ◽  
Vol 14 (6) ◽  
pp. 670-675 ◽  
Author(s):  
Do-Young Park ◽  
Young-Tae Ahn ◽  
Chul-Sung Huh ◽  
Seon-Min Jeon ◽  
Myung-Sook Choi

2015 ◽  
Vol 12 (3) ◽  
pp. 479-484
Author(s):  
Baghdad Science Journal

In this study Candida speices was diagnosed in 26 swab samples from patients with denture stomatitis , investigates the antagonism activity of Lactobacillus was investigated against the yeast of Candida albicans in vitro.Results revealed that The inhibition effect of Lactic Acid Bacteria against C.albicans was examined in solid medium, L.plantarum gave higher inhibition average 11mm followed by L.acidophillus with average 9 mm and, L.fermentum , L.casei with averages 7 mm. Whereas the filtrates, the highest inhibition zone were 20 and 16 mm by L. plantarum and L.acidophillus, respectively.


2018 ◽  
Vol 8 (9) ◽  
pp. 1498 ◽  
Author(s):  
Jing Zhang ◽  
Xianrong Zhou ◽  
Benshou Chen ◽  
Xingyao Long ◽  
Jianfei Mu ◽  
...  

Chinese Paocai is a traditional fermented food containing an abundance of beneficial microorganisms. In this study, the microorganisms in Szechwan Paocai were isolated and identified, and a strain of lactic acid bacteria (Lactobacillus plantarum CQPC10, LP-CQPC10) was found to exert an inhibitory effect on constipation. Microorganisms were isolated and identified via 16S rDNA. Activated carbon was used to induce constipation in a mouse model and the inhibitory effect of LP-CQPC10 on this induced constipation was investigated via both pathological sections and qPCR (quantitative polymerase chain reaction). A strain of Lactobacillus plantarum was identified and named LP-CQPC10. The obtained results showed that, as compared to the control group, LP-CQPC10 significantly inhibited the amount, weight, and water content of faeces. The defecation time of the first tarry stool was significantly shorter in LP-CQPC10 groups than in the control group. The activated carbon progradation rate was significantly higher when compared to the control group and the effectiveness was improved. LP-CQPC10 increased the serum levels of MTL (motilin), Gas (gastrin), ET (endothelin), AchE (acetylcholinesterase), SP (substance P), and VIP (vasoactive intestinal peptide), while decreasing the SS (somatostatin) level. Furthermore, it improved the GSH (glutathione) level and decreased the MPO (myeloperoxidase), MDA (malondialdehyde), and NO (nitric oxide) levels. The results of qPCR indicated that LP-CQPC10 significantly up-regulated the mRNA expression levels of c-Kit, SCF (stem cell factor), GDNF (glial cell-derived neurotrophic factor), eNOS (endothelial nitric oxide synthase), nNOS (neuronal nitric oxide synthase), and AQP3 (aquaporin-3), while down-regulating the expression levels of TRPV1 (transient receptor potential cation channel subfamily V member 1), iNOS (inducible nitric oxide synthase), and AQP9 (aquaporin-9). LP-CQPC10 showed a good inhibitory effect on experimentally induced constipation, and the obtained effectiveness is superior to that of Lactobacillus bulgaricus, indicating the better probiotic potential of this strain.


2020 ◽  
Vol 85 (11) ◽  
pp. 3920-3926
Author(s):  
Luana Izzo ◽  
Carlos Luz ◽  
Alberto Ritieni ◽  
Juanma Quiles Beses ◽  
Jordi Mañes ◽  
...  

Toxins ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 636 ◽  
Author(s):  
Zhao ◽  
Zhang ◽  
Folly ◽  
Chang ◽  
Wang ◽  
...  

Lactobacillus plantarum, as a natural bio-preservative, has attracted a great deal of attention in recent years. In this study, 22 L. plantarum strains were tested against the aflatoxin-producing fungus, Aspergillus flavus; strain IAMU80070 showed the highest antifungal activity. At a concentration of 5 × 105 colony-forming units (CFU) mL−1, it completely inhibited A. flavus growth and decreased aflatoxin production by 93%. Furthermore, ultrastructural examination showed that IAMU80070 destroyed the cellular structure of hyphae and spores. To explore the inhibitory effect of IAMU80070 on A. flavus at the transcriptional level, transcriptome data were obtained and subjected to Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. The aflatoxin biosynthetic process was the most significantly downregulated functional category, while genes implicated in the synthesis and organization of cell wall polysaccharides were upregulated. Quantitative real-time PCR results verified the credibility and reliability of the RNA sequencing data. These results provided insight into the transcriptome of A. flavus in response to the antagonistic effects of L. plantarum IAMU80070.


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