Total Body Water and Intracellular Water Relationships with Muscle Strength, Frailty and Functional Performance in an Elderly Population. A Cross-Sectional Study

2018 ◽  
Vol 23 (1) ◽  
pp. 96-101 ◽  
Author(s):  
Mateu Serra-Prat ◽  
I. Lorenzo ◽  
E. Palomera ◽  
S. Ramírez ◽  
J. C. Yébenes
Keyword(s):  
Muscle Strength ◽  
Total Body Water ◽  
Elderly Population ◽  
Functional Performance ◽  
Cross Sectional Study ◽  
Body Water ◽  
Intracellular Water ◽  
Sectional Study ◽  
Cross Sectional ◽  
Total Body

scholarly journals Intracellular Water Content in Lean Mass is Associated with Muscle Strength, Functional Capacity, and Frailty in Community-Dwelling Elderly Individuals. A Cross-Sectional Study

Nutrients ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 661 ◽  
Author(s):  
Mateu Serra-Prat ◽  
Isabel Lorenzo ◽  
Elisabet Palomera ◽  
Juan Yébenes ◽  
Lluís Campins ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Elderly People ◽  
Functional Capacity ◽  
Lean Mass ◽  
Functional Performance ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Intracellular Water ◽  
Sectional Study ◽  
Cross Sectional

High intracellular water (ICW) content has been associated with better functional performance and a lower frailty risk in elderly people. However, it is not clear if the protective effect of high ICW is due to greater muscle mass or better muscle quality and cell hydration. We aimed to assess the relationship between ICW content in lean mass (LM) and muscle strength, functional performance, frailty, and other clinical characteristics in elderly people. In an observational cross-sectional study of community-dwelling subjects aged ≥75 years, ICW and LM were estimated by bioelectrical impedance, and the ICW/LM ratio (mL/kg) calculated. Muscle strength was measured as hand grip, frailty status was assessed according to Fried criteria, and functional status was assessed by Barthel score. For 324 recruited subjects (mean age 80 years), mean (SD) ICW/LM ratio was 408 (29.3) mL/kg. The ICW/LM ratio was negatively correlated with age (rs = −0.249; p < 0.001). A higher ICW/LM ratio was associated with greater muscle strength, better functional capacity, and a lower frailty risk, even when adjusted by age, sex, nº of co-morbidities, and LM. ICW content in LM (including the muscle) may influence muscle strength, functional capacity and frailty. However, further studies are needed to confirm this hypothesis.

What Total Body Water Measurement Should Be Used for Prescribing the Dialysis Dose in Low-Flow Home Daily Dialysis?

2021 ◽  
pp. 1-8
Author(s):  
Nicolas Gautier ◽  
Jerome Sampol ◽  
Elie Zagdoun ◽  
Simon Duquennoy ◽  
Diomaye Jean Pierre Dione ◽  
...  
Keyword(s):  
Total Body Water ◽  
Cross Sectional Study ◽  
Body Water ◽  
Low Flow ◽  
Dialysis Dose ◽  
Cross Sectional ◽  
Entire Cohort ◽  
Daily Dialysis ◽  
Total Body ◽  
The Impact

<b><i>Introduction:</i></b> In low-flow home daily dialysis (HDD), the dialysis dose is evaluated from the total body water (TBW). TBW can be estimated by anthropometric methods or bioimpedance spectroscopy. <b><i>Methods:</i></b> A multicentric cross-sectional study of patients in HDD for &#x3e;3 months was conducted to assess the correlation and the difference between the anthropometric estimate of TBW (Watson-TBW) and the bioimpedance estimate (BIS-TBW) and to analyse the impact on the dialysate volume prescribed. <b><i>Results:</i></b> Forty patients from 10 centres were included. The median BIS-TBW and Watson-TBW were 35.1 (29.1–41.4 L) and 36.9 (32–42.4 L), respectively. The 2 methods had a good correlation (<i>r</i> = 0.87, <i>p</i> &#x3c; 0.05). However, Bland-Altman analysis showed an overestimation of TBW with Watson’s formula, with a bias of 2.77 L. For 4, 5, or 6 sessions per week, the use of Watson-TBW increases the dialysate prescription per week by 100 L, 45 L, or 10 L, respectively, over our entire cohort. There is no increase in the volume of dialysate prescribed with the 7 sessions per week schedule. <b><i>Conclusion:</i></b> BIS-TBW and Watson-TBW estimation have a good correlation; however, Watson’s equation overestimates TBW. This overestimation is negligible for a prescription frequency of &#x3e;5 sessions per week.

scholarly journals Prevalence of disabilities and non-communicable diseases in an elderly population in the Telangana state, India: a population-based cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e041755
Author(s):  
Srinivas Marmamula ◽  
Satya Brahmanandam Modepalli ◽  
Thirupathi Reddy Kumbham ◽  
Rajesh Challa ◽  
Jill E Keeffe
Keyword(s):  
Elderly Population ◽  
Self Care ◽  
The Elderly ◽  
Population Based ◽  
Cross Sectional Study ◽  
Communicable Diseases ◽  
Self Report ◽  
Sectional Study ◽  
Cross Sectional ◽  
Non Communicable Diseases

ObjectivesTo assess the prevalence of disabilities (vision, hearing, mobility, cognitive, self-care and communication) and non-communicable diseases (NCDs) among the elderly population in two districts in Telangana, India.DesignPopulation-based cross-sectional study using a cluster random sampling method to select the study clusters.SettingElderly population in Khammam and Warangal districts were recruited. Detailed interviews were conducted by trained community health workers. Personal and demographic information such as age, gender, level of education and a self-report of NCDs was collected. The Washington Disability Questionnaire was administered to assess the presence of disabilities.Participants1821 participants aged ≥60 years, 54.5% were women, and 73.3% had no education.Primary outcome measurePrevalence of disabilities and NCDs.ResultsOverall, the prevalence of at least disability was 20.3% (95% CI 16.3 to 24.9). The prevalence of self- reported disabilities were: seeing (5.9%; 95% CI 4.4 to 7.8), mobility (12.8%; 95% CI 9.7 to 16.8), hearing (3.6%; 95% CI 2.7 to 4.8), cognition (4.8%; 95% CI 3.5 to 6.7), self-care (3.3%; 95% CI 2.3 to 4.7) and communication (1.8%; 95% CI 1.2 to 2.6). Overall, the prevalence of at least one NCD was 34.2% (95% CI 30.9 to 37.7). Hypertension was the most common systemic condition (25.4%; 95% CI 22.4 to 28.7), followed by diabetes (9.0%; 95% CI 7.3 to 11.0), and body pains (muscle-skeletal) (9.9%; 95% CI 8.1 to 12.2).ConclusionEvery fifth elderly person in the districts of Khammam and Warangal in Telangana had at least one self-reported disability. Besides, a third of the elderly had at least one NCD. There is a definite need to develop comprehensive public health strategies to address disabilities and NCDs in Telangana.

scholarly journals Associations between exposure to perfluoroalkyl substances and body fat evaluated by DXA and MRI in 109 adolescent boys

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Mathilde Lolk Thomsen ◽  
Louise Scheutz Henriksen ◽  
Jeanette Tinggaard ◽  
Flemming Nielsen ◽  
Tina Kold Jensen ◽  
...  
Keyword(s):  
Body Fat ◽  
Study Design ◽  
Sulfonic Acid ◽  
Standard Deviation Score ◽  
Cross Sectional Study ◽  
Mass Spectrometry Data ◽  
Perfluoroalkyl Substances ◽  
Sectional Study ◽  
Cross Sectional ◽  
Total Body

Abstract Background Exposure to perfluoroalkyl substances (PFASs) has been associated with changes in body mass index and adiposity, but evidence is inconsistent as study design, population age, follow-up periods and exposure levels vary between studies. We investigated associations between PFAS exposure and body fat in a cross-sectional study of healthy boys. Methods In 109 boys (10–14 years old), magnetic resonance imaging and dual-energy X-ray absorptiometry were performed to evaluate abdominal, visceral fat, total body, android, gynoid, android/gynoid ratio, and total fat percentage standard deviation score. Serum was analysed for perfluorooctanoic acid, perfluorooctane sulfonic acid (PFOS), perfluorohexane sulfonic acid, perfluorononanoic acid, and perfluorodecanoic acid using liquid chromatography and triple quadrupole mass spectrometry. Data were analysed by multivariate linear regression. Results Serum concentrations of PFASs were low. Generally, no clear associations between PFAS exposure and body fat measures were found; however, PFOS was negatively associated with abdominal fat (β = -0.18, P = 0.046), android fat (β = -0.34, P = 0.022), android/gynoid ratio (β = -0.21, P = 0.004), as well as total body fat (β = -0.21, P = 0.079) when adjusting for Tanner stage. Conclusions Overall, we found no consistent associations between PFAS exposure and body fat. This could be due to our cross-sectional study design. Furthermore, we assessed PFAS exposure in adolescence and not in utero, which is considered a more vulnerable time window of exposure.

scholarly journals Increased modifiable cardiovascular risk factors in patients with Takayasu arteritis: a multicenter cross-sectional study

2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Alexandre Moura dos Santos ◽  
Rafael Giovani Misse ◽  
Isabela Bruna Pires Borges ◽  
Bruno Gualano ◽  
Alexandre Wagner Silva de Souza ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Muscle Strength ◽  
Aerobic Capacity ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Metabolic Equivalent ◽  
Handgrip Test

Abstract Background Modifiable cardiovascular risk factors (MCRFs), such as those related to aerobic capacity, muscle strength, physical activity, and body composition, have been poorly studied in Takayasu arteritis (TAK). Therefore, the aim of the study was to investigate MCRFs and their relationships with disease status and comorbidities among patients with TAK. Methods A multicenter cross-sectional study was conducted between 2019 and 2020, in which 20 adult women with TAK were compared with 16 healthy controls matched by gender, age, and body mass index. The following parameters were analyzed: aerobic capacity by cardiopulmonary test; muscle function by timed-stands test, timed up-and-go test, and handgrip test; muscle strength by one-repetition maximum test and handgrip test; body composition by densitometry; physical activity and metabolic equivalent by IPAQ, quality of life by HAQ and SF-36; disease activity by ITAS2010 and NIH score; and presence of comorbidities. Results Patients with TAK had a mean age of 41.5 (38.0–46.3) years, disease duration of 16.0 (9.5–20.0) years, and a mean BMI of 27.7±4.5 kg/m2. Three out of the 20 patients with TAK had active disease. Regarding comorbidities, 16 patients had systemic arterial hypertension, 11 had dyslipidemia, and two had type 2 diabetes mellitus, while the control group had no comorbidities. TAK had a significant reduction in aerobic capacity (absolute and relative VO2 peak), muscle strength in the lower limbs, increased visceral adipose tissue, waist-to-hip ratio, reduced walking capacity, decreased weekly metabolic equivalent, and quality of life (P< 0.05) as compared to controls. However, there were no correlations between these MCRFs parameters and disease activity. Conclusions TAK show impairment in MCRFs; therefore, strategies able to improve MCRF should be considered in this disease.

scholarly journals Total body bone measurements: A cross-sectional study in children with acute lymphoblastic leukemia during and following completion of therapy

2009 ◽  
Vol 52 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Kara M. Kelly ◽  
John C. Thornton ◽  
Deborah Hughes ◽  
Ifeyinwa Osunkwo ◽  
Michael Weiner ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Total Body ◽  
Body Bone
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