scholarly journals Large-Scale Beard Extraction Enhances the Cosmetic Results of Scalp Hair Restoration in Advanced Androgenetic Alopecia in East Asian Men: A Retrospective Study

2019 ◽  
Vol 10 (1) ◽  
pp. 151-161
Author(s):  
De-Cong Zhu ◽  
Ye He ◽  
Zhe-Xiang Fan ◽  
Jin Wang ◽  
Qian Qu ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Large Scale ◽  
Scalp Hair ◽  
East Asian ◽  
Androgenetic Alopecia ◽  
Cosmetic Results ◽  
Asian Men

Parts of South-east Asia may adopt nuclear post-2030

2021 ◽  
Keyword(s):  
East Asia ◽  
Nuclear Power ◽  
Large Scale ◽  
East Asian ◽  
Energy Development ◽  
South East Asia ◽  
Asian Countries ◽  
Content Type ◽  
Electricity Grid ◽  
Renewable Energy Development

Significance It is the only country in South-east Asia with a large-scale nuclear plant, although this was never loaded with fuel. Other countries in the region have tentative plans to develop nuclear power programmes. Impacts The current absence of nuclear power programmes will help avert the diversion of capital from renewable energy development in the region. South-east Asian countries with small, non-power reactors, built for research, will try to maintain these facilities. Across the region, the need for electricity grid investment will increase as more decentralised generation sources are deployed.

scholarly journals Characteristics of a large-scale cohort with accessory pathway(s): A cross-sectional retrospective study highlighting over a twenty-year experience

2021 ◽  
Vol 49 (6) ◽  
pp. 456-462
Author(s):  
Suat Gormel ◽  
◽  
Salim Yasar ◽  
Serkan Asil ◽  
Erhan Bozkurt ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Large Scale ◽  
Accessory Pathway ◽  
Cross Sectional

scholarly journals Association of the Poleward Shift of East Asian Subtropical Upper-Level Jet with Frequent Tropical Cyclone Activities over the Western North Pacific in Summer

2017 ◽  
Vol 30 (14) ◽  
pp. 5597-5603 ◽  
Author(s):  
Xian Chen ◽  
Zhong Zhong ◽  
Wei Lu
Keyword(s):  
Tropical Cyclone ◽  
North Pacific ◽  
Western North Pacific ◽  
Large Scale ◽  
East Asian ◽  
Teleconnection Pattern ◽  
Reanalysis Dataset ◽  
Poleward Shift ◽  
Upper Level ◽  
Upper Level Jet

The NCEP–NCAR reanalysis dataset and the tropical cyclone (TC) best-track dataset from the Regional Specialized Meteorological Center (RSMC) Tokyo Typhoon Center were employed in the present study to investigate the possible linkage of the meridional displacement of the East Asian subtropical upper-level jet (EASJ) with the TC activity over the western North Pacific (WNP). Results indicate that summertime frequent TC activities would create the poleward shift of the EASJ through a stimulated Pacific–Japan (PJ) teleconnection pattern as well as the changed large-scale meridional temperature gradient. On the contrary, in the inactive TC years, the EASJ is often located more southward than normal with an enhanced intensity. Therefore, TC activities over the WNP are closely related to the location and intensity of the EASJ in summer at the interannual time scale.

scholarly journals Insights into the Unique Nature of the East Asian Clade of the Emerging Pathogenic Yeast Candida auris

2019 ◽  
Vol 57 (4) ◽  
Author(s):  
Rory M. Welsh ◽  
D. Joseph Sexton ◽  
Kaitlin Forsberg ◽  
Snigdha Vallabhaneni ◽  
Anastasia Litvintseva
Keyword(s):  
Large Scale ◽  
East Asian ◽  
Candida Auris ◽  
Pathogenic Yeast ◽  
Content Type ◽  
New Information ◽  
Asian Clade ◽  
Single Region ◽  
Invasive Infections ◽  
Unique Nature

ABSTRACT The emerging yeast Candida auris can be highly drug resistant, causing invasive infections, and large outbreaks. C. auris went from an unknown pathogen a decade ago to being reported in over thirty countries on six continents. C. auris consists of four discrete clades, based on where the first isolates of the clade were reported, South Asian (clade I), East Asian (clade II), African (clade III), and South American (clade IV). These clades have unique genetic and biochemical characteristics that are important to understand and inform the global response to C. auris. Clade II has been underrepresented in the literature despite being the first one discovered. In this issue of the Journal of Clinical Microbiology, Y. J. Kwon et al. (J Clin Microbiol 57:e01624-18, 2019, https://doi.org/10.1128/JCM.01624-18) describe the largest collection of clinical isolates from Clade II, which is also the longest-running span of clinical cases, 20 years, from any single region to date. Clade II appears to have a propensity for the ear that is uncharacteristic of the other clades, which typically cause invasive infections and large-scale outbreaks. This study provides new information on an understudied lineage of C. auris and has important implications for future surveillance.

scholarly journals Recent prescription status of oral analgesics in Japan in real-world clinical settings: retrospective study using a large-scale prescription database

2019 ◽  
Vol 20 (16) ◽  
pp. 2041-2052 ◽  
Author(s):  
Takahiro Ushida ◽  
Daiju Matsui ◽  
Teruyoshi Inoue ◽  
Mizuka Yokoyama ◽  
Hiroshi Takatsuna ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Real World ◽  
Large Scale ◽  
Clinical Settings ◽  
Prescription Database ◽  
Prescription Status

Ribavirin for Hepatitis E Virus Infection After Organ Transplantation: A Large European Retrospective Multicenter Study

2019 ◽  
Vol 71 (5) ◽  
pp. 1204-1211 ◽  
Author(s):  
Nassim Kamar ◽  
Florence Abravanel ◽  
Patrick Behrendt ◽  
Jörg Hofmann ◽  
Georges Phillippe Pageaux ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Retrospective Study ◽  
Multicenter Study ◽  
Virological Response ◽  
Hepatitis E Virus ◽  
Large Scale ◽  
Organ Transplant ◽  
Hepatitis E ◽  
Solid Organ Transplant ◽  
Solid Organ

Abstract Background Ribavirin is currently recommended for treating chronic hepatitis E virus (HEV) infection. This retrospective European multicenter study aimed to assess the sustained virological response (SVR) in a large cohort of solid organ transplant (SOT) recipients with chronic HEV infection treated with ribavirin monotherapy (N = 255), to identify the predictive factors for SVR, and to evaluate the impact of HEV RNA mutations on virological response. Methods Data from 255 SOT recipients with chronic HEV infection from 30 European centers were analyzed. Ribavirin was given at the median dose of 600 (range, 29–1200) mg/day (mean, 8.6 ± 3.6 mg/kg/day) for a median duration of 3 (range, 0.25–18) months. Results After a first course of ribavirin, the SVR rate was 81.2%. It increased to 89.8% when some patients were offered a second course of ribavirin. An increased lymphocyte count at the initiation of therapy was a predictive factor for SVR, while poor hematological tolerance of ribavirin requiring its dose reduction (28%) and blood transfusion (15.7%) were associated with more relapse after ribavirin cessation. Pretreatment HEV polymerase mutations and de novo mutations under ribavirin did not have a negative impact on HEV clearance. Anemia was the main adverse event. Conclusions This large-scale retrospective study confirms that ribavirin is highly efficient for treating chronic HEV infection in SOT recipients and shows that the predominant HEV RNA polymerase mutations found in this study do not affect the rate of HEV clearance. This large-scale retrospective study that included 255 solid organ transplant recipients confirms that ribavirin is highly efficient for treating chronic hepatitis E virus (HEV) infection and shows that HEV RNA polymerase mutations do not play a role in HEV clearance.

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