scholarly journals Methoprene, a juvenile hormone analogue, modifies maturation and emergence in overwintering Osmia rufa L. adults

Apidologie ◽  
2021 ◽  
Author(s):  
Karol Giejdasz ◽  
Monika Fliszkiewicz ◽  
Oskar Wasielewski
Keyword(s):  
Juvenile Hormone ◽  
Reproductive Traits ◽  
Early Spring ◽  
Control Groups ◽  
Hormone Analogue ◽  
Experimental Conditions ◽  
Greenhouse Crops ◽  
Incubation Periods ◽  
Negative Controls ◽  
And Control

AbstractThe development of methods aimed at activation of imagos at any point of wintering provides a compelling potential avenue to utilize bees for pollination of greenhouse crops during autumn, winter, and early spring. In this study, we tested methoprene, a juvenile hormone (JH) analogue as a chemical stimulant to end a diapause of Osmia rufa L. and enable bee activation and emergence under experimental conditions. The application of methoprene significantly reduced the emergence time of adult bees in winter months as compared to vehicle (acetone) and negative controls. Bees treated with methoprene started to emerge 3–6 days earlier than bees from acetone and control groups and finished emergence 2–6 days earlier too. Statistically significant differences were observed between methoprene and controls groups of male and female in all tested incubation periods. It was also observed that the effects of methoprene were significantly more effective in female specimens during the first 2 months of winter. Moreover, in females, methoprene improved reproductive traits such as an increase in the size of terminal oocytes. Similarly, in males, methoprene treatment resulted in a significant increase in a seminal vesicle size and dynamic elevation of spermatozoa number. Taken together, our results indicate that methoprene may play an important role in the termination of diapause, bee activation, and emergence.

Obstetric antiphospholipid syndrome is not associated with an increased risk of subclinical atherosclerosis

Rheumatology ◽  
2020 ◽  
Vol 59 (12) ◽  
pp. 3709-3716 ◽  
Author(s):  
Alessandra Bettiol ◽  
Giacomo Emmi ◽  
Martina Finocchi ◽  
Elena Silvestri ◽  
Maria Letizia Urban ◽  
...  
Keyword(s):  
Subclinical Atherosclerosis ◽  
Intima Media Thickness ◽  
Control Groups ◽  
Carotid Plaques ◽  
Increased Risk ◽  
Obstetric Antiphospholipid Syndrome ◽  
Obstetric Aps ◽  
Negative Controls ◽  
And Control

Abstract Objectives The persistent positivity of aPLs, either isolated or associated with thrombotic and/or obstetric events (APS), has been associated with the increase of intima-media thickness (IMT) and carotid plaques. Despite the fact that aPLs can promote both thrombotic and obstetric complications, some pathogenic differences have been documented between the two entities. This study aimed to evaluate whether the atherosclerotic risk differs between subjects with obstetric and thrombotic APS. Methods A total of 167 APS women (36 obstetric and 131 thrombotic) were compared with 250 aPLs negative controls. IMT of the common carotid artery (CCA) and of the bulb and the prevalence of carotid plaques were assessed. Results CCA- and bulb-IMT were significantly higher in women with thrombotic APS, while being similar between the obstetric APS and the controls [CCA-IMT: mean (s.d.) 0.97 (0.49), 0.78 (0.22) and 0.81 (0.12) mm for the thrombotic, obstetric and control groups, respectively, P < 0.001 between thrombotic and controls, P = 0.002 between thrombotic and obstetric; bulb-IMT: mean (s.d.) 1.38 (0.79), 0.96 (0.27) and 0.96 (0.51) mm for the thrombotic, obstetric and control groups, P < 0.001]. Women with thrombotic APS had significantly increased risk of presenting carotid plaques. This risk was significantly lower in obstetric APS. Conclusion Unlike thrombotic APS, obstetric APS is not associated with an increase of markers of subclinical atherosclerosis. If confirmed on wider populations, these results could suggest different pathogenetic role of aPLs in promoting atherosclerosis in vascular and obstetric APS, and raise questions on the risk–benefit profile of thromboprophylaxis in obstetric APS outside pregnancy periods.

scholarly journals Methoprene and Temperature Stimulation of Emergence and Longevity in Adults of Osmia Rufa L. (Megachilidae; Apoidea) During Wintering Period

2017 ◽  
Vol 61 (1) ◽  
pp. 139-147
Author(s):  
Karol Giejdasz ◽  
Oskar Wasielewski
Keyword(s):  
Juvenile Hormone ◽  
Sucrose Solution ◽  
Adult Males ◽  
Control Groups ◽  
Juvenile Hormone Analogues ◽  
Males And Females ◽  
Rate Of Emergence ◽  
And Control ◽  
Temperature Stimulation ◽  
Stimulation Of

Abstract In this study methoprene, a juvenile hormone analogues, was tested as a factor that stimulates the end of diapause, bee activation and emergence. In addition, the survival of bees was checked when combined with an application of methoprene. The experimental activation of wintering bees was carried out once a month between December and March, Three groups of bee cocoons were selected for each activation term: treated with either methoprene or acetone as vehicle control and untreated as controls. After the applications were finished the cocoons were incubated at temperature 26°C. The emerged adult males and females were then kept in the laboratory and fed sucrose solution to evaluate the longevity of bees. The application of juvenile hormone analogue reduced the emergence time of adult bees in December, February and March. The rate of emergence presented in the form of cumulative percentage of emerged adult bees indicated that the bees treated with methoprene started to emerge 1-2 days earlier than bees from acetone and control groups and finished emergence 2-5 days earlier too. Methopren application did not reduce the longevity of the bees after emergence. Moreover, the median longevity of these females was higher than untreated in December and February.

Effects of Paraphrasing, Modeling, and Cues in Facilitating Self-Referent Affective Statements by Chronic Schizophrenics

1980 ◽  
Vol 47 (2) ◽  
pp. 523-536 ◽  
Author(s):  
Robert D. Citkowitz ◽  
Leah Blumberg Lapidus
Keyword(s):  
Experimental Period ◽  
Control Group ◽  
Control Groups ◽  
Experimental Conditions ◽  
Warm Up ◽  
Modeling And Control ◽  
Chronic Schizophrenic ◽  
Chronic Schizophrenics ◽  
Affect Expression ◽  
And Control

This study investigates the effects of paraphrasing, modeling with controlled disclosure of congruent feelings by an interviewer and cues on the verbalized expression of self-referent affect of chronic schizophrenic inpatients. The 17 male and 43 female subjects were randomly assigned in a 3 × 2 design comprising Paraphrasing, Modeling and Control groups, each with Cue and Non-cue subgroups. An independent interviewer presented a standardized introduction, specific instructions for expressing self-referent affect and a brief warm-up period. A 30-min. quasiclinical interview of three successive 10-min. periods followed: Base I, Experimental, and Base II. During the Experimental period, paraphrasing, modeling, or control treatments were introduced with either cue or non-cue conditions. As predicted, modeling, both with and without cues, significantly increased self-referent affect expression over control group levels. Contrary to prediction, paraphrasing was ineffective and significantly inferior to modeling. Cues significantly enhanced the effects of paraphrasing and modeling, as predicted, and increased Base I period self-referent affect level. Maintaining the cue condition prevented extinction of self-referent affect following termination of experimental conditions. Effect of sex was nonsignificant. Relative superiority of modeling over paraphrasing in clinical interventions with chronic schizophrenics was discussed.

scholarly journals Achieving Equitable Uptake of Handwashing and Sanitation by Addressing Both Supply and Demand-based Constraints: Findings From a Randomized Controlled Trial in Rural Bangladesh 

2020 ◽  
Author(s):  
Sarker Masud Parvez ◽  
Musarrat Jabeen Rahman ◽  
Rashidul Azad ◽  
Mahbubur Rahman ◽  
Leanne Unicomb ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Supply And Demand ◽  
Efficacy Trial ◽  
Control Groups ◽  
Experimental Conditions ◽  
Randomized Controlled ◽  
Education Levels ◽  
Change Promotion ◽  
And Control ◽  
The Impact

Abstract Background: Supply driven programs that are not closely connected to community demand and demand-driven programs that fail to ensure supply both risk worsening inequity. Understanding patterns of uptake of behaviors among the poorest under ideal experimental conditions, such as those of an efficacy trial, can help identify strategies that could be strengthened in routine programmatic conditions for more equitable uptake. WASH Benefits Bangladesh was a randomized controlled efficacy trial that provided free-of cost WASH hardware along with behavior change promotion. The current paper aimed to determine the impact of the removal of supply and demand constraints on the uptake of handwashing and sanitation behaviors across wealth and education levels.Methods: The current analysis selected 4 indicators from the WASH Benefits trial— presence of water and soap in household handwashing stations, observed mother’s hand cleanliness, observed visible feces on latrine slab or floor and reported last child defecation in potty or toilet. A baseline assessment was conducted immediately after enrolment and endline assessment was conducted approximately 2 years later. We compared change in uptake of these indicators including wealth quintiles (Q) between intervention and control groups from baseline to endline.Results: For hand cleanliness, the poorest mothers improved more (Q1 difference in difference, DID: 16%) than the wealthiest mothers (Q5 DID: 7%). The poorest households had largest improvements for observed presence of water and soap in handwashing station (Q1 DID: 82%) compared to the wealthiest households (Q5 DID: 39%). Similarly, poorer household demonstrated greater reductions in visible feces on latrine slab or floor (Q1DID, -25% Q2: -34%) than the wealthiest household (Q5 DID: -1%). For reported last child defecation in potty or toilet, the poorest mothers showed greater improvement (Q1-4 DID: 50-54%) than the wealthier mothers (Q5 DID: 39%). Conclusion: By simultaneously addressing supply and demand-constraints among the poorest, we observed substantial overall improvements in equity. Within scaled-up programs, a separate targeted strategy that relaxes constraints for the poorest can improve the equity of a program. Trial registration: WASH Benefits Bangladesh: ClinicalTrials.gov, identifier: NCT01590095. Date of registration: April 30, 2012 ‘Retrospectively registered’URL: https://clinicaltrials.gov/ct2/show/NCT01590095

scholarly journals Achieving equitable uptake of handwashing and sanitation by addressing both supply and demand-based constraints: Findings from a randomized controlled trial in rural Bangladesh

2020 ◽  
Author(s):  
Sarker Masud Parvez ◽  
Musarrat Jabeen Rahman ◽  
Rashidul Azad ◽  
Mahbubur Rahman ◽  
Leanne Unicomb ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Supply And Demand ◽  
Efficacy Trial ◽  
Control Groups ◽  
Experimental Conditions ◽  
Randomized Controlled ◽  
Education Levels ◽  
Change Promotion ◽  
And Control ◽  
The Impact

Abstract Background: Supply driven programs that are not closely connected to community demand and demand-driven programs that fail to ensure supply both risk worsening inequity. Understanding patterns of uptake of behaviors among the poorest under ideal experimental conditions, such as those of an efficacy trial, can help identify strategies that could be strengthened in routine programmatic conditions for more equitable uptake. WASH Benefits Bangladesh was a randomized controlled efficacy trial that provided free-of cost WASH hardware along with behavior change promotion. The current paper aimed to determine the impact of the removal of supply and demand constraints on the uptake of handwashing and sanitation behaviors across wealth and education levels.Methods: The current analysis selected 4 indicators from the WASH Benefits trial— presence of water and soap in household handwashing stations, observed mother’s hand cleanliness, observed visible feces on latrine slab or floor and reported last child defecation in potty or toilet. A baseline assessment was conducted immediately after enrolment and endline assessment was conducted approximately 2 years later. We compared change in uptake of these indicators including wealth quintiles (Q) between intervention and control groups from baseline to endline.Results: For hand cleanliness, the poorest mothers improved more [Q1 difference in difference, DID: 16% (7, 25%)] than the wealthiest mothers [Q5 DID: 7% (-4, 17%)]. The poorest households had largest improvements for observed presence of water and soap in handwashing station [Q1 DID: 82% (75, 90%)] compared to the wealthiest households [Q5 DID: 39% (30, 50%)]. Similarly, poorer household demonstrated greater reductions in visible feces on latrine slab or floor [Q1DID, -25% (-35, -15) Q2: -34% (-44, -23%)] than the wealthiest household [Q5 DID: -1% (-11, 8%). For reported last child defecation in potty or toilet, the poorest mothers showed greater improvement [Q1-4 DID: 50-54% (44, 60%)] than the wealthier mothers [Q5 DID: 39% (31, 46%). Conclusion: By simultaneously addressing supply and demand-constraints among the poorest, we observed substantial overall improvements in equity. Within scaled-up programs, a separate targeted strategy that relaxes constraints for the poorest can improve the equity of a program. Trial registration: WASH Benefits Bangladesh: ClinicalTrials.gov, identifier: NCT01590095. Date of registration: April 30, 2012 ‘Retrospectively registered’URL: https://clinicaltrials.gov/ct2/show/NCT01590095

scholarly journals The effects of a sled push at different loads on 20 metre sprint time in well-trained soccer players

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Nick Grimes ◽  
Jorge Arede ◽  
Benjamin Drury ◽  
Steve Thompson ◽  
John Fernandes
Keyword(s):  
Body Mass ◽  
Repeated Measures ◽  
Soccer Players ◽  
Control Group ◽  
Control Groups ◽  
Experimental Conditions ◽  
Repeated Measures Anova ◽  
Sprint Time ◽  
And Control ◽  
Experimental Group

This study determined the effects of a single sled push at different loads on sprint performance in competitive male soccer players. Twenty male competitive outfield soccer players (age 19.6±1.3y, body mass 73.6±8.2kg) were split into experimental (n=10) and control groups. In the experimental group, 20m linear sprint time was measured immediately before and 5, 6 and 7minutes after the sled push with either 50 or 100% body mass. The control group performed the 20m sprints only. A repeated measures ANOVA comparing control and experimental groups revealed no effects of time, group or time by group interaction for either experimental condition (all P>0.05). The repeated measures ANOVA compared the experimental conditions revealed effects of time (P=0.034) and group (P=0.002), but not time by group (P>0.05). The effects sizes demonstrated within group effects on sprint time that were small to moderate (-0.26 to 0.71) and trivial to small (-0.31 to 0.09) for the 50% and 100% body mass condition, respectively. These findings demonstrate that a sled push has no significant effect on 20 m sprint time in competitive footballers. If coaches continue to prescribed a sled push before sprinting, a single 15 m push with 50% body mass could have positive benefits.

Effects of Writing Summaries as a Generative Learning Activity during Note Taking

1997 ◽  
Vol 24 (1) ◽  
pp. 47-49 ◽  
Author(s):  
Martha Davis ◽  
Richard E. Hult
Keyword(s):  
Free Recall ◽  
Relative Effectiveness ◽  
Learning Activity ◽  
Control Group ◽  
Generative Learning ◽  
Note Taking ◽  
Control Groups ◽  
Experimental Conditions ◽  
Summary Writing ◽  
And Control

Two experimental conditions of note taking in lecture sections of Introductory Psychology were compared for their relative effectiveness as generative-learning activities. The summary group students took notes during a 21-min lecture and wrote three lecture summaries during 4-min pauses. The pause group students took notes during lecture but only reviewed their notes during the pauses. The control group students took notes without pauses. Immediately following the lecture, students took a posttest, 12 days later they responded to a free-recall question and took another posttest. Although the pause and control groups did not differ on any measure, the summary group scored significantly higher than the control group on the free-recall question and 12-day posttest, suggesting that summary writing during lecture results in more durable learning.

Conjugated Linoleic Acid Causes a Marked Increase in Liver α-Tocopherol and Liver α-Tocopherol Transfer Protein in C57BL/6 J Mice

2010 ◽  
Vol 80 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pei-Min Chao ◽  
Wan-Hsuan Chen ◽  
Chun-Huei Liao ◽  
Huey-Mei Shaw
Keyword(s):  
Antioxidant Enzymes ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Thiobarbituric Acid ◽  
Control Group ◽  
Thiobarbituric Acid Reactive Substances ◽  
Control Groups ◽  
Protein Levels ◽  
Transfer Protein ◽  
And Control

Conjugated linoleic acid (CLA) is a collective term for the positional and geometric isomers of a conjugated diene of linoleic acid (C18:2, n-6). The aims of the present study were to evaluate whether levels of hepatic α-tocopherol, α-tocopherol transfer protein (α-TTP), and antioxidant enzymes in mice were affected by a CLA-supplemented diet. C57BL/6 J mice were divided into the CLA and control groups, which were fed, respectively, a 5 % fat diet with or without 1 g/100 g of CLA (1:1 mixture of cis-9, trans-11 and trans-10, cis-12) for four weeks. α-Tocopherol levels in plasma and liver were significantly higher in the CLA group than in the control group. Liver α-TTP levels were also significantly increased in the CLA group, the α-TTP/β-actin ratio being 2.5-fold higher than that in control mice (p<0.01). Thiobarbituric acid-reactive substances were significantly decreased in the CLA group (p<0.01). There were no significant differences between the two groups in levels of three antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase). The accumulation of liver α-tocopherol seen with the CLA diet can be attributed to the antioxidant potential of CLA and the ability of α-TTP induction. The lack of changes in antioxidant enzyme protein levels and the reduced lipid peroxidation in the liver of CLA mice are due to α-tocopherol accumulation.

The Prospects and Risks Connected with Increasing the Level of Self-Organisation in Students

2020 ◽  
pp. 75-81
Author(s):  
Svetlana Alexandrovna Kosareva ◽  
Keyword(s):  
Higher Education ◽  
Professional Competence ◽  
Initial Level ◽  
Education Institution ◽  
Diagnostic Methods ◽  
Study Guide ◽  
Learning Approaches ◽  
Control Groups ◽  
Self Organisation ◽  
And Control

The paper describes the method for increasing the level of self-organisation in students which has been developed by the author. It also contains the method testing results and presents the prospects and risks teachers could face while applying the method in a higher education institution. The purpose of this study is to find out the prospects and risks of applying the method for increasing the level of self-organisation in students and to determine the ways of reducing the risks. Methodology. The author points out the learning approaches which were the basis of developing the method and describes diagnostic methods for determining students’ self-organisation levels. The work focused on increasing each student’s initial level consists of a theoretical and a practical part and includes project activities on creating a study guide. The results of the study. The method developed proved to be effective. It was established by diagnosing the final level of self-organisation in students in the experimental and control groups. The paper considers the advantages of the method among which there is universal character, flexibility, improvements to teacher’s and students’ professional competence, etc. At the same time it is necessary to be aware of the risks due to the increased amount of teacher’s work and the fact that students’ work within the project tends to be monotonous. In conclusion, the prospects of the method for increasing the level of self-organisation in students are related to its advantages and the final results of the work. The risks of its use can be reduced with the help of the measures proposed in the paper.

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