scholarly journals Radiation recall phenomenon after administration of the mRNA-1273 SARS-CoV-2 vaccine

2022 ◽  
Author(s):  
Yojiro Ishikawa ◽  
Rei Umezawa ◽  
Takaya Yamamoto ◽  
Noriyoshi Takahashi ◽  
Kazuya Takeda ◽  
...  
Keyword(s):  
Skin Reaction ◽  
Interesting Case ◽  
Burning Sensation ◽  
Axillary Lymph ◽  
Total Mastectomy ◽  
Radiation Recall ◽  
Acute Side Effect ◽  
Systemic Medication ◽  
Irradiation Field ◽  
The Relationship

AbstractSeveral types of SARS-CoV-2 vaccine have been developed. However, the relationship between SARS-CoV-2 vaccine and radiation therapy (RT) is unclear. Recently, there have been some reports of radiation recall phenomenon (RRP) caused by a SARS-CoV-2 vaccine. We report a case of RRP after administration of the mRNA-1273 SARS-CoV-2 vaccine. A 51-year-old female was diagnosed with breast cancer (cT4N1M0, cStage IIIB) and underwent breast total mastectomy with axillary lymph node dissection after neoadjuvant chemotherapy. After mastectomy, the patient received RT with 50 Gy in 25 fractions. An acute side effect of grade 2 dermatitis according to the National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0. occurred after RT. The patient had not started any new systemic medication after RT; however, the patient received the mRNA-1273 SARS-CoV-2 vaccine (Moderna) 1 month after the end of the initial RT. Seven days after vaccination, the patient had a skin reaction with burning sensation and redness. This skin reaction was induced in an area corresponding to the irradiation field of the chest wall. There was no skin reaction in areas other than that described. The reaction was cured within 1 week with topical hydrocortisone. This report is an interesting case report with a RPP after administration of the mRNA-1273 SARS-CoV-2 vaccine.

scholarly journals Trastuzumab induced radiation recall dermatitis: an interesting case

2018 ◽  
Vol 7 (12) ◽  
pp. 2465
Author(s):  
Anupama C. ◽  
Anuradha H. V. ◽  
Vinayak V. Maka
Keyword(s):  
Ductal Carcinoma ◽  
Growth Factor Receptor ◽  
Radical Mastectomy ◽  
Left Breast ◽  
Interesting Case ◽  
Axillary Lymph ◽  
Radiation Recall ◽  
Skin Reactions ◽  
Radiation Recall Dermatitis ◽  
Recall Dermatitis

Radiation recall dermatitis (RRD) is the appearance of skin reactions in previously irradiated skin which is triggered by the administration of certain drugs. Surgery, chemotherapy, and radiotherapy are the mainstay of treatment in breast cancer. RRD induced by trastuzumab has been rarely reported in India. This is a case report of a 56-year-old woman presented to the medical oncology outpatient department of our hospital with breast lump, and she was diagnosed to have human epidermal growth factor receptor 2 (HER-2/neu) positive invasive ductal carcinoma of left breast of stage T2N3cM0. She was treated with neoadjuvant chemotherapy, and she underwent modified radical mastectomy with axillary lymph node dissection. The treating oncologist was planned to start on adjuvant chemotherapy with injection trastuzumab for every four weeks, for 15 cycles. Patient received first dose of injection trastuzumab (450 mg) intravenously in the right (contralateral) arm and developed painful, swollen, erythematous blisters, and maculopapular rashes following the sharp linear borders of her previous radiation fields. She was reviewed by the medical oncologist and diagnosed as a rare case of RRD and treated with topical betamethasone cream. Causality assessment for RRD to trastuzumab was done using Naranjo and WHO-UMC scale and found to be in the category of probable and probable/ likely respectively.

Toward a Philosophical Approach of the Hermeneutics of the Qur’an

2006 ◽  
Vol 23 (1) ◽  
pp. 15-34
Author(s):  
Aliaa Ibrahim Dakroury
Keyword(s):  
Modern Technology ◽  
Interesting Case ◽  
Philosophical Approach ◽  
True Meaning ◽  
Flow Of Information ◽  
The Relationship

Although claims questioning whether religious sacred books can be “translated” or not have been heard for quite some time, they have increased with the emergence of globalization and the increasing openness and flow of information due to modern technology. In the context of the relationship between hermeneutics and communication, one could argue that interpreting the Qur’an is an interesting case study for many reasons. Among them is the number of debates and discourses that have been raised both for and against its translation. Another reason, perhaps one of the largest barriers according to some religious Muslim groups, is that the Qur’an is fundamentally revealed and written in Arabic, and, therefore, its true meaning cannot be translated into another language. Certain verses, such as “It is a Qur’an in Arabic, without any crookedness (therein): in order that they may guard against evil” (28:39), have been presented to support this argument.

The European Union’s Policy towards its Eastern Neighbours: The Crisis in Ukraine

2018 ◽  
Author(s):  
Tatsiana Shaban
Keyword(s):  
Crisis Management ◽  
Policy Development ◽  
Interesting Case ◽  
European Neighbourhood Policy ◽  
Significant Progress ◽  
Challenges And Opportunities ◽  
External Governance ◽  
Institutional Challenges ◽  
The Relationship ◽  
The Eu

The European Union’s neighbourhood is complex and still far from being stable. In Ukraine, significant progress has occurred in many areas of transition; however, much work remains to be done, especially in the field of regional development and governance where many legacies of the Soviet model remain. At the crossroads between East and West, Ukraine presents an interesting case of policy development as an expression of European Union (EU) external governance. This paper asks the question: why was the relationship between the EU and Ukraine fairly unsuccessful at promoting stability in the region and in Ukraine? What was missing in the European Neighbourhood Policy (ENP) in Ukraine that rendered the EU unable to prevent a conflict on the ground? By identifying security, territorial, and institutional challenges and opportunities the EU has faced in Ukraine, this paper underlines the most important factors accounting for the performance of its external governance and crisis management in Ukraine.   Full text available at: https://doi.org/10.22215/rera.v12i2.1310

Toward a Philosophical Approach of the Hermeneutics of the Qur’an

2006 ◽  
Vol 23 (1) ◽  
pp. 15-34
Author(s):  
Aliaa Ibrahim Dakroury
Keyword(s):  
Modern Technology ◽  
Interesting Case ◽  
Philosophical Approach ◽  
True Meaning ◽  
Flow Of Information ◽  
The Relationship

Although claims questioning whether religious sacred books can be “translated” or not have been heard for quite some time, they have increased with the emergence of globalization and the increasing openness and flow of information due to modern technology. In the context of the relationship between hermeneutics and communication, one could argue that interpreting the Qur’an is an interesting case study for many reasons. Among them is the number of debates and discourses that have been raised both for and against its translation. Another reason, perhaps one of the largest barriers according to some religious Muslim groups, is that the Qur’an is fundamentally revealed and written in Arabic, and, therefore, its true meaning cannot be translated into another language. Certain verses, such as “It is a Qur’an in Arabic, without any crookedness (therein): in order that they may guard against evil” (28:39), have been presented to support this argument.

PRIMARY UNDIFFERENTIATED PLEOMORPHIC SARCOMA OF BREAST IN A 24 YEAR FEMALE : A CASE REPORT

2021 ◽  
pp. 57-58
Author(s):  
Sona Pathak ◽  
Manoj Kumar Paswan ◽  
Arpana ShailalyTirkey ◽  
Joyeeta Mandal
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
Histopathological Examination ◽  
Axillary Lymph ◽  
High Grade ◽  
Node Dissection ◽  
Total Mastectomy ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Pleomorphic Sarcoma ◽  
Adolescents And Adults

Undifferentiated pleomorphic sarcoma constitutes less than 5 % of all sarcomas in adults and has been rarely seen in the breast and is dened as a group of pleomorphic, high-grade sarcomas in which any attempt to disclose their line of differentiation has failed . Most undifferentiated pleomorphic sarcomas(UPS) have occurred in their sixth and seventh decades of life and very rarely in adolescents and adults. We report a case of 24 year old female presented with painless lump in right breast and rapidly increasing in size for last 5 months. Iinitial diagnosis was made as sarcoma breast on the basis of physical and radiological examination. After that total mastectomy was done without axillary lymph node dissection, as lymphatic spread is very rare. But without histopathological examination and most importantly IHC-panel, it is impossible to make a denitive diagnosis of UPS breast.

scholarly journals Socio-Economic Drivers, Land Cover Changes and the Dynamics of Rural Settlements: Mt. Matese Area (Italy)

2017 ◽  
Vol 9 (3) ◽  
pp. 435-457 ◽  
Author(s):  
Maria Bonaventura Forleo ◽  
Vincenzo Giaccio ◽  
Agostino Giannelli ◽  
Luigi Mastronardi ◽  
Nadia Palmieri
Keyword(s):  
Land Cover ◽  
Interesting Case ◽  
Population Characteristics ◽  
Land Cover Changes ◽  
Rural Settlements ◽  
Difficult Situation ◽  
Current Scenario ◽  
The Relationship ◽  
Development Prospects

Abstract The paper elaborates on the relationship between land cover changes and transformation drivers, by analysing the dynamics that took place between 1990 and 2010 in Mt. Matese area (Italy). Mt. Matese is an interesting case study which was included as a pilot area in the Italian Strategy for Inner Areas. Drivers related to land cover changes include population characteristics, the agricultural and production system, tourist offer, location and settlements dynamics. Land cover changes and the dynamics of studied drivers are analysed in-depth, through a descriptive and multivariate analysis. Results highlight the difficult situation of the study area for many drivers. However, the slow changes in land cover and the potentialities offered by the natural environment, as well as by the agriculture and tourism sectors, outline some development prospects. The paper outlines the current scenario in the area and provides useful references for future policies aimed at setting up this area as National Park and at implementing the Strategy for Inner Areas.

Corporate Governance Models as a Bridge for Linking Academic and Non-Academic Entrepreneurs

2011 ◽  
Vol 25 (2) ◽  
pp. 119-131 ◽  
Author(s):  
Roberto Parente ◽  
Rosangela Feola ◽  
Michele Petrone
Keyword(s):  
Corporate Governance ◽  
Interesting Case ◽  
New Venture ◽  
Entrepreneurial Opportunity ◽  
Sample Group ◽  
Academic Entrepreneurs ◽  
Governance Model ◽  
Academic Inventors ◽  
Governance Models ◽  
The Relationship

This paper reports an investigation of governance issues in Italian academic spin-offs that arise from the need to balance the powers of two categories of partner: academic inventors and external investors (such as established companies and venture capital funds). The relationship between inventors and external investors, jointly pursuing a research-based entrepreneurial opportunity, provides an interesting case for the application of the agency theory construct to define adequate corporate governance procedures. The paper has two main objectives: to analyse the governance models adopted by academic spin-offs and to ascertain whether the very nature of entrepreneurial opportunity, and the associated uncertainties that a new venture faces, influence the choice of the governance model adopted. A sample group of 30 Italian academic spin-offs is analysed and three different governance models, inventor-led spin-offs, mixed-led spin-offs and investor-led spin-offs, are defined.

Coordinating concurrent legal orders in the prosecution of international crimes

2013 ◽  
Vol 2 (2) ◽  
pp. 316-344
Author(s):  
BEATRICE I. BONAFÉ
Keyword(s):  
Criminal Law ◽  
International Criminal ◽  
Interesting Case ◽  
International Criminal Law ◽  
International Crimes ◽  
The Individual ◽  
The Relationship

AbstractInternational criminal law provides a particularly interesting case study for the proliferation of legal orders as it helps to understand the types of uncertainties their interaction may entail with respect to the position of the individual as well as the solutions that may be adopted in that respect. This article analyses a selected number of substantive and procedural uncertainties that originate in the relationship between international criminal law and domestic legal orders. The purpose of the discussion is to identify the particular legal devices that have been elaborated in order to ensure the coordination between these legal orders, and to suggest areas in which a better coordination is still to be achieved.

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