Clinical spectrum, treatment and outcome of myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease in children: a tertiary care experience

Author(s):  
Hepsen Mine Serin ◽  
Sanem Yilmaz ◽  
Erdem Simsek ◽  
Seda Kanmaz ◽  
Cenk Eraslan ◽  
...  
Author(s):  
Abed AlLehbi ◽  
Abdullah AlMtawa ◽  
Adel Alqutub ◽  
Khalid Alsayari ◽  
Ahmed Alomair ◽  
...  

2017 ◽  
Vol 4 (5) ◽  
pp. 310-314
Author(s):  
Dr. Maheswari K ◽  
◽  
Dr. Shanmuga Arumugasamy S ◽  
Dr. Manikandasamy V ◽  
Dr. Shafna Azeez ◽  
...  

2018 ◽  
Vol 137 ◽  
pp. 35-39 ◽  
Author(s):  
Ozlem Satırer ◽  
Ayse Mete Yesil ◽  
Nagehan Emiralioglu ◽  
Gökcen Dilsa Tugcu ◽  
Ebru Yalcın ◽  
...  

2021 ◽  
Vol 8 (10) ◽  
pp. 1566
Author(s):  
Vinay Jishtu ◽  
Pramod K. Jaret ◽  
Prem Chand Machhan ◽  
Nidhi Chauhan

Background: Acute undifferentiated fever illness (AUFI) is a common cause of morbidity and mortality in developing countries, owing to its non-specific features. The aim of the study was to delineate the causes and clinical parameters associated with AUFI.Methods: A cross-sectional study was done among 156 patients of AUFI, admitted in the Department of Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India, from November 2018 to October 2019.Results: The mean age of the study participants was 37.37±14.2 years. The study participants admitted for acute undifferentiated febrile illness had fever with mean duration of 8.38±3.7 days before hospitalization. The most common aetiology of AUFI was found to be enteric fever (44%), followed by scrub typhus (35%). The majority of the cases presented from the month of September to December.Conclusions: The aetiology and clinical spectrum of AUFI is wide and variable. To outline a proper algorithm to contain it, meticulous analysis of the hospital data at each level is necessary.


2017 ◽  
Vol 4 (2) ◽  
pp. 438
Author(s):  
Bhavana Koppad ◽  
Kulkarni Poornima Prakash

Background: Candidial infections are a serious problem in neonatal intensive care units (NICU) which increases the mortality and morbidity in addition to increasing health care costs. Confirming the diagnosis by laboratory tests is difficult and a high index of suspicion is required. The objective of this study was to identify the clinical spectrum and epidemiology of neonatal candidiasis in a tertiary care NICU.Methods: The present study was carried out in the NICU of SDM medical college and hospital, Dharwad. All babies who were admitted to NICU and who had positive blood culture for Candida were included in the study. One year Data (1st December 2015 to 31st November 2016) was collected retrospectively from NICU case records. Statistical test used was chi square test.Results: Total admissions to the NICU during the study period were 2591. Blood cultures were positive in 132 babies. Among these, Candidial sepsis was noted in 39.39% (52) babies. Out of the 52 positive fungal cultures, 15 were Candida albicans, 35 were Candida non albicans and 2 were mixed cultures (Candida albicans and non albicans) showing an increasing incidence of non-albicans Candida infections. Among the non albicans Candida, Candida tropicalis and Candida guilliermondii were the predominant species (11 each) followed by Candida famata (6), Candida krusei (6) and Candida parapsilosis (3). Candidial sepsis was seen to be more common among preterm and low birth weight babies. Usage of antibiotics, Total parenteral nutrition (TPN) and mechanical ventilation were common risk factors noted in our study.Conclusions: Systemic Candidiasis is a disease of modern neonatal intensive care. It deserves urgent attention for its prevention as well as effective treatment in order to minimize neonatal morbidity and mortality.


Author(s):  
Rangaraj Murugaiyan

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Childhood vitiligo is a special subtype and is seen in significant proportion of vitiligo patients. There are only a few clinical studies in the past which address the clinical spectrum of vitiligo in children. This study on eighty cases of childhood vitiligo will cover the epidemiology and clinical spectrum.</span></p><p class="abstract"><strong>Methods:</strong> To study the epidemiology, clinical spectrum and associations in childhood vitiligo. Inclusion criteria: all new cases of vitiligo in children under 12 years attending the outpatient department of Dermatology, exclusion criteria: old treated cases of vitiligo and age more than 12 years. Statistical analysis was done using mean and percentage of means.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Most common age group affected includes 4-6 years. Most common site of initial lesion was head and neck followed by upper limb, lower limb and trunk. Most common clinical type was vitiligo vulgaris followed by focal type then segmental. Lip tip type was least common type. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Childhood vitiligo is a serious issue and the knowledge of its various patterns and associations needs to be updated at regular intervals.</span></p>


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