Estimation of secondary metabolites of indigenous medicinal plant extracts and their in vitro and in vivo efficacy against tomato early blight disease in Pakistan

2019 ◽  
Vol 126 (6) ◽  
pp. 553-563
Author(s):  
Sobia Chohan ◽  
Rashida Perveen ◽  
Muhammad Anees ◽  
Muhammad Azeem ◽  
Muhammad Abid
2005 ◽  
Vol 77 (1) ◽  
pp. 41-51 ◽  
Author(s):  
A. Gurib-Fakim ◽  
H. Subratty ◽  
F. Narod ◽  
J. Govinden-Soulange ◽  
F. Mahomoodally

The Mauritian population has a long tradition in the use of ethno-medicine, and the practice is still strong, especially in the treatment of minor ailments. Such interest stems from an existing culture, and many “tisanes” are still prepared from plant materials and sold in several markets around the island.This paper will focus on the various chemical/biological screening techniques currently being used to evaluate the biological properties of medicinal plant extracts. Particular emphasis will be put on extraction and various screening for biological/pharmacological properties. Due consideration will be given to the pharmacological approaches that utilize different animal models for the in vitro and in vivo screening of medicinal plant extracts.


2020 ◽  
Vol 08 ◽  
Author(s):  
Eugenia Dumitra Teodor ◽  
Gabriel Lucian Radu

Background:: Phyto, or plant-derived metal nanoparticles are an interesting and intensive studied group of green synthesized nanoparticles. In the last decade, numerous medicinal plant extracts were used to the synthesis of stable gold or silver nanoparticles with diverse biological effects, such as antioxidant activity, antimicrobial activity, antiinflammatory activity, hypoglycemic effect, antitumor activity and catalytic activity. Results:: This review has systematized and discussed information from the last 5 years about the research regarding antitumor/anticancer potential of gold nanoparticles obtained via medicinal plant extracts, with special attention on their selective cytotoxicity on tumor cells and on their mechanism of action, in vitro and in vivo assessments. Conclusion:: Much more in vivo and clinical studies are needed before considering phyto-synthesized gold nanoparticles as significant for future medicine.


Author(s):  
Meseret Tadelo ◽  
Tamirat Wato ◽  
Tilahun Negash

Background: Tomato (Lycopersicon esculentum Mill.) belongs to the family Solanaceae. In Ethiopia, control of early blight is largely dependent on fungicidal application. There is a research need to identify effective botanical extracts to control Alternaria solani that cause early blight of tomato and for evaluation of plant extracts through different solvents on the target pathogen. Methods: In vitro experiment was conducted to evaluate the effectiveness of crude extracts of 16 selected medicinal plants against Alternaria solani. Thus, crude extracts were extracted from medicinal plants with different solvents (methanol, ethanol and petroleum at (25%, 50% and 100%) concentrations. The Alternaria solani was isolated from infected tomato leaves showing early blight symptoms. Evaluation of plant extracts was carried out against Alternaria solani using food poisoned technique on PDA. Result: Results showed that most of the methanolic extract plants were showed significant inhibition of the mycelial growth as compared to ethanolic and petroleum ether extracts. A higher rate of mycelial reduction was recorded by ethanol extracts of Allium sativum at all concentrations (100%) followed by methanol extracts of Allium sativum at 25%, 50%, 100% concentration (90.02%, 97.01%, 100% respectively). The effectiveness of extracts against Alternaria solani depends on use at the higher concentrations and various solvents. For crude extracts that have shown higher inhibitory effects against Alternaria solani in vitro conditions, actual chemical compounds should be identified. Furthermore, it is also important to evaluate these plants on other microbes, study to test in vivo and to assess their real potential field condition wherever early blight is an important disease of tomato.


2003 ◽  
Vol 60 (3) ◽  
pp. 175-180 ◽  
Author(s):  
Vimolmas Lipipun ◽  
Masahiko Kurokawa ◽  
Rutt Suttisri ◽  
Pagorn Taweechotipatr ◽  
Pornpen Pramyothin ◽  
...  

2020 ◽  
Vol 219 ◽  
pp. 108011 ◽  
Author(s):  
Cheryl Sachdeva ◽  
Dinesh Mohanakrishnan ◽  
Sandeep Kumar ◽  
Naveen Kumar Kaushik

2012 ◽  
Vol 48 (No. 2) ◽  
pp. 74-79 ◽  
Author(s):  
S.M.A. Nashwa ◽  
K.A.M. Abo-Elyousr

The antimicrobial activity of six plant extracts from Ocimum basilicum (Sweat Basil), Azadirachta indica (Neem), Eucalyptus chamadulonsis (Eucalyptus), Datura stramonium (Jimsonweed), Nerium oleander (Oleander), and Allium sativum (Garlic) was tested for controlling Alternaria solani in vitro and in vivo. In in vitro study the leaf extracts of D. stramonium, A. indica, and A. sativum at 5% concentration caused the highest reduction of mycelial growth of A. solani (44.4, 43.3 and 42.2%, respectively), while O. basilicum at 1% and 5% concentration and N. oleander at 5% concentration caused the lowest inhibition of mycelial growth of the pathogen. In greenhouse experiments the highest reduction of disease severity was achieved by the extracts of A. sativum at 5% concentration and D. stramonium at 1% and 5% concentration. The greatest reduction of disease severity was achieved by A. sativum at 5% concentration and the smallest reduction was obtained when tomato plants were treated with O. basilicum at 1% and 5% concentration (46.1 and 45.2 %, respectively). D. stramonium and A. sativum at 5% concentration increased the fruit yield by 76.2% and 66.7% compared to the infected control. All treatments with plant extracts significantly reduced the early blight disease as well as increased the yield of tomato compared to the infected control under field conditions.


2018 ◽  
Vol 15 (1) ◽  
Author(s):  
Omonike O. Ogbole ◽  
Toluwanimi E. Akinleye ◽  
Peter A. Segun ◽  
Temitope C. Faleye ◽  
Adekunle J. Adeniji

2010 ◽  
Vol 52 (5) ◽  
pp. 383-388 ◽  
Author(s):  
Young-Suk Choi ◽  
Kang-Duk Choi ◽  
Sung-Do Kim ◽  
Owens Phillip ◽  
Chung-Soo Chung

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