scholarly journals Senile Cataract in Patients with Diabetes with and Without Diabetic Retinopathy: A Community-Based Comparative Study

Author(s):  
Khalid Mohammad Alabdulwahhab

Abstract Aim We compare the incidence rates of cataract in persons with diabetes with and without diabetic retinopathy in Saudi Arabia, for the first time. In addition, we explored the role of new factor, diabetes age of onset and several other known factors. Methods In a community-based cross-sectional study, 334 persons with diabetes type 2 were randomly selected from a diabetic register. Detailed history and comprehensive ophthalmic examination was done at an eye clinic. Body Mass Index, blood pressure and glycosylated hemoglobin were also recorded. Results In 668 eyes, cataract and diabetic retinopathy were present in 35.5% and 32.2%, respectively. Diabetic retinopathy, age, duration of diabetes and systolic BP were found to be independent risk factors for cataract. Whereas, gender, BMI, HbA1c use of insulin and diastolic BP have no significant association with cataract. Persons with cataract had significantly higher age of onset of diabetes. Most of the cataracts were cortical followed by PSC, while minority were nuclear. Conclusion DR is an independent risk factor of developing cataract in persons with diabetes. Others are age, duration of DM and hypertension. Age-of-onset of DM is a new factor we report it to be significantly associated with cataract.

BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e016210 ◽  
Author(s):  
Kjersti Wendt ◽  
Ronny Kristiansen ◽  
Kirsten Krohg-Sørensen ◽  
Fredrik Alexander Gregersen ◽  
Erik Fosse

ObjectiveThe numbers of lower extremity revascularisations and amputations are insufficiently reported in Norway. To support future policy decisions regarding the provision of vascular treatment, knowledge of such trends is important.MethodsThis retrospective cross-sectional study from 2001 to 2014 used data from the Norwegian Patient Registry. The revascularisation treatments were categorised in multilevel, aortoiliac, femoral to popliteal and popliteal to foot levels and sorted as open, endovascular and hybrid. The sessions in amputations were divided in major (thigh and below knee) and minor (ankle, foot or digit). Incidence rates were assessed per 100 000 for patients in the age group>60 years. The diabetic prevalence was calculated and the endovascular numbers at the South-Eastern, Western, Central and Northern Norway Regional Health Authority were compared.ResultsThe overall revascularisation rates increased from 308.7 to 366.8 (p=0.02). Open revascularisations decreased from 158.9 to 98.7 (p<0.01) while endovascular revascularisations increased from 142.2 to 243.4 (p<0.01). Hybrid revascularisations increased from 7.4 to 24.8 (p<0.01). Major amputation rates decreased from 87.8 to 48.7 (p<0.01) while minor amputations increased from 12.3 to 19.6 (p=0.01). The diabetic percentages increased from 12.2 to 22.3 (p<0.01) in revascularisations, from 26.5 to 30.8 (p=0.02) in major amputations and from 43.0 to 49.3 (p=0.13) in minor. (p values refer to average annual changes.) The regional trends in endovascular treatments varied within and between the vascular groups.ConclusionFrom 2001 to 2014, the revascularisation rates increased due to the rise in endovascular procedures. Open revascularisations and major amputation rates decreased, minor increased. The regional variances in endovascular treatments indicate that the availability of this technology differed between the health regions of Norway. The increase in patients with diabetes requires continued awareness of diabetes and its complications.


Author(s):  
Daniel Zamanfar ◽  
Pooneh Yazdani ◽  
Mohsen Aarabi ◽  
Hedieh Pournorooz

Introduction: The prevalence of type 1 diabetes in all countries throughout the world is different. In this study, an introduction is, therefore, provided for the development of type 1 diabetes in children in Mazandaran province by using all available resources.Methods: In this descriptive cross-sectional study, the prevalence of patients with initial diagnosis of type 1 diabetes mellitus, aging from 6 months to 18 years, was located through contacting and referring to all organizations of insurers and doctors or experts in children endocrinologist and adolescent diseases in Mazandaran province.Results: 289 patients with type 1 diabetes were identified, 138 of whom were male (47.8%), and 151 were women (52.2%) with an overall prevalence of 0.04%, and the rate of this prevalence was 48 cases among 100000 people (50 cases among 100000 girls and 36 cases among 100000 boys). The mean age of the patients was 11.5 years old. In the study of delivery method, 180 patients (62.3%) were diagnosed with cesarean section, and 109 (37.7%) were born through natural delivery method. The mean age of onset of diabetes was 7 years. The minimum and maximum ages were 7 months and 18 years, respectively. 97 (33.6%) of the patients were also hospitalized for the first time due to ketoacidosis, and were diagnosed with diabetes.Conclusion: Type 1 diabetes in Mazandaran province was more prevalent than the similar study in southern Iran and neighboring countries. It is essential to pay greater attention to this disease through studying it in the other parts of the country.


BMJ Open ◽  
2017 ◽  
Vol 7 (8) ◽  
pp. e015473 ◽  
Author(s):  
Jing Cui ◽  
Ji-Ping Ren ◽  
Dong-Ning Chen ◽  
Zhong Xin ◽  
Ming-Xia Yuan ◽  
...  

ObjectivesThe study aimed to determine the exact risk factors for diabetic retinopathy (DR) in the Chinese population using a cohort of 17  985 individuals from Beijing, China.DesignCross-sectional study.SettingA hospital.Participants17  985 individuals from Beijing, China.Primary and secondary outcome measuresThis was a cross-sectional study of permanent residents from the Changping area (Beijing, China) recruited from July 2010 to March 2011 and from March 2014 to February 2015 during a routine health examination at the Tongren Hospital of Beijing. Eye examinations were conducted by experienced ophthalmologists. Medical history, height, weight, body mass index (BMI) and blood pressure were recorded. Routine laboratory examinations were performed.ResultsThe prevalence of DR was 1.5% in the general study population and 8.1% among individuals with diabetes. Compared with the non-DR group, individuals in the DR group in the diabetes population had longer disease duration, higher systolic blood pressure (SBP), fasting plasma glucose (FPG) and uric acid (UA) (in men) and lower UA (in women) (all p<0.05). The multivariate analysis showed that disease duration (p<0.001), BMI (p=0.046), SBP (p=0.012), creatinine clearance rate (CCR) (p=0.014), UA (p=0.018) and FPG (p<0.001) were independently associated with DR in patients with diabetes.ConclusionThe prevalence of DR was 8.1% among patients with diabetes. Disease duration, BMI, SBP, CCR, UA and FPG were independently associated with DR.


2019 ◽  
Vol 4 (1) ◽  
pp. e000236 ◽  
Author(s):  
Raju Sapkota ◽  
Zhiqing Chen ◽  
Dingchang Zheng ◽  
Shahina Pardhan

Background/aimsTo examine the profile of diabetic retinopathy, awareness and self-help in patients attending a specialist eye clinic in Hangzhou, China.MethodsA total of 199 consecutive patients with diabetes (mean age = 57 years, SD = 11) attending eye clinic at the School of Medicine, Zhejiang University, Hangzhou were examined in a cross-sectional study. Clinical/demographic data were obtained from patients’ records. Fundus photographs obtained from each patient were graded using Early Treatment of Diabetic Retinopathy Study (ETDRS) criteria; severe non-proliferative, proliferative retinopathy and/or macular oedema (hard exudates/thickening around fovea) were classified as sight-threatening diabetic retinopathy (STDR). Optical coherence tomography was used to confirm the diagnosis of macular oedema. Data on knowledge/awareness about diabetes and self-help/lifestyle were collected using a structured questionnaire.ResultsSTDR was found in 80% patients of whom 18% had visual acuity of ≤counting fingers in at least one eye. Male gender, longer diabetic duration and use of insulin were significantly associated with STDR (p ≤ 0.05). Of the total, 41% patients reported that they were attending for the first time. Of all the first-time attendees, 67% had STDR. Also of all the first-time attendees, 14% were unclear whether diabetes affected their eyes. Fifty-one per cent of patients who thought their diabetes was well controlled had fasting blood sugar ≥6.5 mmol/L (p < 0.001). Of the total, 65% patients reported not doing ≥4 hours/week of physical exercise.ConclusionsThe majority of patients with diabetes presented to this eye clinic suffered with late-stage retinopathy. Our results advocate the need to improve diabetic diagnosis, management and awareness and to set up eye screening for diabetics in Hangzhou, China.


2016 ◽  
Vol 23 (05) ◽  
pp. 571-575
Author(s):  
Rao Muhammad Rashad Qamar ◽  
Sadiq Hussain Hussain ◽  
Rao Muhammad Aslam Tariq

Objectives: The purpose of this study was to evaluate the prevalence andcharacteristics of diabetic retinopathy (DR) in patients attending the free eye camps for cataractsurgery held in southern Punjab, Pakistan. Study Design: It was a cross sectional study. Setting:Free eye camps organized in different regions of the Southern Punjab, Pakistan. Period: July2004 to June 2015. Material and methods: These community-based eye camps were held bythe Department of Ophthalmology in collaboration of department of Pathology, B.V. Hospital,Bahawalpur, Pakistan. Participants were interviewed and examined by the ophthalmologists todetermine their demographic characteristics, presence & duration of medical conditions andthe regularity of their visits to eye care providers. All patients screened to have diabetes mellitus(DM) by pathologists underwent an eye examination through dilated pupils by using direct/indirect ophthalmoscope and slit-lamp bio-microscope to check for any signs of DR. Mainoutcome measure was the presence of diabetic retinopathy and its complications, which wasclassified as mild, moderate, severe NPDR, and proliferative diabetic retinopathy (PDR) basedon the clinical examination. Results: Of the 7989 screened patients, 759 (9.5%) had type-II DM.Of them, 638 patients (84%) underwent eye examination. Mean age of the diabetics was 45.75 ±8.17 years. Diabetic retinopathy was prevalent in 93 (15%) patients followed by non-proliferativeretinopathy was found in 87 (93.5%) patients and proliferative retinopathy was found only in 6(6.5%) patients. More male 52 (20.39%) were effected of DR as compare to female 41 (10.7%).Highly significant association of DR with duration of DM was seen. (P: 0.001). Conclusion: Itis concluded in this study that DR is commonly prevalent in Southern Punjab and the mostcommon type of DR is non-proliferative retinopathy. DR frequently prevalent in male diabeticsas compare to female diabetics and significant association of duration of DM with DR wasfound.


2020 ◽  
Author(s):  
Abdulrahman Abdullah Al-Yahya ◽  
Abdulrahman Almizel ◽  
Alwaleed Mohammad Alsulaiman ◽  
Abdulrahman Mohammed barri ◽  
fadwa aladel

Abstract Objective To identify the knowledge, attitude, practice (KAP) of diabetes and diabetic retinopathy among Saudi patients with diabetes in Riyadh Saudi Arabia.Methods A cross sectional study that was conducted in 50 randomly selected primary care centers and two university hospitals, involving diabetic patients that are 18 years and older during May 2018 and December 2018 in Riyadh, Saudi Arabia, using a validated KAP-45 questionnaire to assess the KAP levels of diabetes and diabetic retinopathy.Results A total of 313 participants were enrolled in the study. Most of them 168(59.8%) were males and 38(12.3%) were illiterate and 141(45.4%) had at least a bachelor's degree. Most of them had a family history of DM and long standing history of DM The average knowledge score for diabetes was good and was suboptimal for diabetic retinopathy. While the attitude scores for both diabetes and diabetic retinopathy were suboptimal. Meanwhile the average practice score for diabetes was good and was low for diabetic retinopathy.Conclusions Findings observed in our study stress on the importance of improving education and awareness as it’s the key for controlling the disease and reducing its complications.


2017 ◽  
Vol 12 (2) ◽  
pp. 89
Author(s):  
Olokoba L B ◽  
Mahmud O A ◽  
Adepoju F G ◽  
Olokoba A B

<p><strong>Background: </strong>Diabetic retinopathy is a major cause of blindness worldwide. The associated loss of productivity and quality of life of the patients with diabetic retinopathy will lead to additional socioeconomic burden. This study aims to determine the level of awareness of diabetic retinopathy among diabetic patients. <strong></strong></p><p><strong>Materials and Methods: </strong>This hospital-based cross sectional study, was carried out at the Diabetic and Ophthalmology clinics of University of Ilorin Teaching Hospital, Nigeria from November 2011 to July 2012. A total of 365<strong> </strong>patients had validated, semi-structured, and interviewer-administered questionnaires to obtain information on socio-demographic characteristics, clinical information and awareness of diabetic retinopathy. <strong></strong></p><p><strong>Results: </strong>A total of 365 patients were enrolled, with age between 19 and 90 years, and a mean of 45.8 ±16.3 years. The male to female ratio was 1: 2.2. Ninety-nine respondents (27.1%) had no education. The majority (30.4%) had only primary education; 21.1% had tertiary; 14.5% had secondary while 6.8% had Quranic education. The mean duration of diabetes mellitus was 14.1 ±13.09 years. Of the 365 patients with diabetes mellitus, 279(76.4%) had heard that diabetes mellitus affects the eyes, while 86(23.6%) had not. Of those who had heard, 221(79.2%) heard it from health personnel, 45(16.1%) from radio/television, 25(9.0%) from internet, 23(8.2%) from books/newspapers, while 16(5.7%) heard from other sources.<strong></strong></p><p><strong>Conclusion: </strong>There was a high level of awareness of diabetic retinopathy amongst the patients. However, the high level of awareness of the blinding complication of diabetes mellitus did not translate to a correspondingly high level of ocular examination for diabetic retinopathy.  <strong></strong></p>


2019 ◽  
Vol 54 (10) ◽  
pp. 605-611 ◽  
Author(s):  
Jannelene Killops ◽  
Martin Schwellnus ◽  
Dina Christina Janse van Rensburg ◽  
Sonja Swanevelder ◽  
Esme Jordaan

BackgroundThere are few data on medical encounters, including deaths during mass-participation cycling events.ObjectiveTo determine the incidence and nature of medical encounters during a community-based mass-participation cycling event.DesignCross-sectional study across three annual events.Setting2012–2014 Cape Town Cycle Tour (109 km), South Africa.Participants102 251 race starters (male=80 354, female=21 897).MethodsMedical encounters (moderate, serious life-threatening, sudden cardiac arrest/death), using the 2019 international consensus definitions, were recorded on race day for 3 years as incidence rates (IR per 1000 starters; 95% CI). Overall illness-related (by organ system) or injury-related (by anatomical region) encounters, and severity were recorded.ResultsWe recorded 539 medical encounters (IR 5.3; 4.8 to 5.7). The IR was 3.2 for injuries (2.9 to 3.6), 2.1 for illnesses (1.0 to 2.4) and 0.5 for serious life-threatening medical encounters (0.4 to 0.7). In the 3-year study, we encountered three cardiac arrests and one death (2.9 and 1.0 per 100 000 starters, respectively). Injury IRs included upper limb (1.9; 1.6 to 2.1), lower limb (1.0; 0.8 to 1.0) and head/neck (0.8; 0.6 to 1.0). Illness IRs included fluid/electrolyte abnormalities (0.6; 0.5 to 0.8) and the cardiovascular system (0.5; 0.4 to 0.6).ConclusionIn a 109 km community-based mass-participation cycling event, medical encounters (moderate to severe) occurred in about 1 in 200 cyclists. Injury-related (1/300 cyclists) encounters were higher than illness-related medical encounters (1 in about 500). Serious life-threatening medical encounters occurred in 1/2000 cyclists. These data allow race organisers to anticipate the medical services required and the approximate extent of demand.


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