scholarly journals The profile of sight-threatening diabetic retinopathy in patients attending a specialist eye clinic in Hangzhou, China

2019 ◽  
Vol 4 (1) ◽  
pp. e000236 ◽  
Author(s):  
Raju Sapkota ◽  
Zhiqing Chen ◽  
Dingchang Zheng ◽  
Shahina Pardhan

Background/aimsTo examine the profile of diabetic retinopathy, awareness and self-help in patients attending a specialist eye clinic in Hangzhou, China.MethodsA total of 199 consecutive patients with diabetes (mean age = 57 years, SD = 11) attending eye clinic at the School of Medicine, Zhejiang University, Hangzhou were examined in a cross-sectional study. Clinical/demographic data were obtained from patients’ records. Fundus photographs obtained from each patient were graded using Early Treatment of Diabetic Retinopathy Study (ETDRS) criteria; severe non-proliferative, proliferative retinopathy and/or macular oedema (hard exudates/thickening around fovea) were classified as sight-threatening diabetic retinopathy (STDR). Optical coherence tomography was used to confirm the diagnosis of macular oedema. Data on knowledge/awareness about diabetes and self-help/lifestyle were collected using a structured questionnaire.ResultsSTDR was found in 80% patients of whom 18% had visual acuity of ≤counting fingers in at least one eye. Male gender, longer diabetic duration and use of insulin were significantly associated with STDR (p ≤ 0.05). Of the total, 41% patients reported that they were attending for the first time. Of all the first-time attendees, 67% had STDR. Also of all the first-time attendees, 14% were unclear whether diabetes affected their eyes. Fifty-one per cent of patients who thought their diabetes was well controlled had fasting blood sugar ≥6.5 mmol/L (p < 0.001). Of the total, 65% patients reported not doing ≥4 hours/week of physical exercise.ConclusionsThe majority of patients with diabetes presented to this eye clinic suffered with late-stage retinopathy. Our results advocate the need to improve diabetic diagnosis, management and awareness and to set up eye screening for diabetics in Hangzhou, China.

2021 ◽  
pp. 28-30
Author(s):  
Tammana Jyothirmai ◽  
P. Beaulah Pushpa ◽  
Maridi Aparna ◽  
Vepa Meenakshi

AIM:To study the association of serum lipids with retinal hard exudates formation, occurrence of clinically signicant macular oedema (CSME) and severity of diabetic retinopathy (DR) in type 2 diabetes METHODS:Type 2 diabetic patients seeking ocular evaluation for diabetic retinopathy were included in this cross-sectional study. They were assessed for presence and severity of diabetic retinopathy (DR), presence of hard exudates, clinically signicant macular oedema (CSME) .Retinal ndings were correlated to serum lipids levels . RESULTS:Totally 100 patients were included, of which 42/100 had diabetic retinopathy of any grade. Retinal hard exudates formation was found to have statistically signicant correlation with the presence of dyslipidemia (p=0.02), increased cholesterol (p=0.002) and LDL levels (p=0.001). The occurrence of CSME showed a statistically signicant correlation with dyslipidemia (p=0.04) and increased LDL levels (p=0.04). Neither occurrence of dyslipidemia nor the increased levels of the various components of serum lipids showed a statistically signicant correlation with high Triglyceride levels or Low HDL-C or increasing severity of diabetic retinopathy CONCLUSION:Elevated serum lipids showed a signicant association with retinal hard exudate formation, CSME in type 2 diabetics. Lipid lowering agents may help in reducing the occurrence of these retinal ndings in diabetic patients.


2021 ◽  
Vol 71 (2) ◽  
pp. 602-05
Author(s):  
Umair Ali ◽  
Muhammad Wajid Munir ◽  
Jahanzeb Maqsood ◽  
Mahwash Jamil ◽  
Syed Saif Ur Rehman ◽  
...  

Objective: To evaluate factors resulting in reluctance of initiation of insulin therapy in patients with type 2 diabetes mellitus. Study Design: Cross sectional study. Place and Duration of Study: Medical OPD of a private tertiary care multi-specialty hospital in Islamabad, from Apr to Jul 2019. Methodology: Patients with diabetes mellitus between age of 30-70 years, who had poor glycaemic control on two oral antidiabetic drugs having HbA1c>9% and were insulin naïve, were included in this study. A validated questionnaire was developed which had two sections; first including the demographic data of the study populations and second having closedended dichotomous questions which were asked from patients by the treating physicians Results: A total of 180 patients with diabetes mellitus eligible for insulin therapy were included in the study, among them 52 (28.9%) were agreed to initiate the insulin. Negative attitude and beliefs include painful way of administration 85 (66.4%), difficult insulin storage 98 (76.6%), risk of hypoglycemia 82 (64.1%).The mean negative perception Score was 7.35 (SD 0.98). Conclusion: Psychological insulin resistance is present in significant diabetic population, and it is a big obstacle in insulin therapy initiation and compliance.


BMJ Open ◽  
2017 ◽  
Vol 7 (8) ◽  
pp. e015473 ◽  
Author(s):  
Jing Cui ◽  
Ji-Ping Ren ◽  
Dong-Ning Chen ◽  
Zhong Xin ◽  
Ming-Xia Yuan ◽  
...  

ObjectivesThe study aimed to determine the exact risk factors for diabetic retinopathy (DR) in the Chinese population using a cohort of 17  985 individuals from Beijing, China.DesignCross-sectional study.SettingA hospital.Participants17  985 individuals from Beijing, China.Primary and secondary outcome measuresThis was a cross-sectional study of permanent residents from the Changping area (Beijing, China) recruited from July 2010 to March 2011 and from March 2014 to February 2015 during a routine health examination at the Tongren Hospital of Beijing. Eye examinations were conducted by experienced ophthalmologists. Medical history, height, weight, body mass index (BMI) and blood pressure were recorded. Routine laboratory examinations were performed.ResultsThe prevalence of DR was 1.5% in the general study population and 8.1% among individuals with diabetes. Compared with the non-DR group, individuals in the DR group in the diabetes population had longer disease duration, higher systolic blood pressure (SBP), fasting plasma glucose (FPG) and uric acid (UA) (in men) and lower UA (in women) (all p<0.05). The multivariate analysis showed that disease duration (p<0.001), BMI (p=0.046), SBP (p=0.012), creatinine clearance rate (CCR) (p=0.014), UA (p=0.018) and FPG (p<0.001) were independently associated with DR in patients with diabetes.ConclusionThe prevalence of DR was 8.1% among patients with diabetes. Disease duration, BMI, SBP, CCR, UA and FPG were independently associated with DR.


2020 ◽  
Author(s):  
Abdulrahman Abdullah Al-Yahya ◽  
Abdulrahman Almizel ◽  
Alwaleed Mohammad Alsulaiman ◽  
Abdulrahman Mohammed barri ◽  
fadwa aladel

Abstract Objective To identify the knowledge, attitude, practice (KAP) of diabetes and diabetic retinopathy among Saudi patients with diabetes in Riyadh Saudi Arabia.Methods A cross sectional study that was conducted in 50 randomly selected primary care centers and two university hospitals, involving diabetic patients that are 18 years and older during May 2018 and December 2018 in Riyadh, Saudi Arabia, using a validated KAP-45 questionnaire to assess the KAP levels of diabetes and diabetic retinopathy.Results A total of 313 participants were enrolled in the study. Most of them 168(59.8%) were males and 38(12.3%) were illiterate and 141(45.4%) had at least a bachelor's degree. Most of them had a family history of DM and long standing history of DM The average knowledge score for diabetes was good and was suboptimal for diabetic retinopathy. While the attitude scores for both diabetes and diabetic retinopathy were suboptimal. Meanwhile the average practice score for diabetes was good and was low for diabetic retinopathy.Conclusions Findings observed in our study stress on the importance of improving education and awareness as it’s the key for controlling the disease and reducing its complications.


2017 ◽  
Vol 12 (2) ◽  
pp. 89
Author(s):  
Olokoba L B ◽  
Mahmud O A ◽  
Adepoju F G ◽  
Olokoba A B

<p><strong>Background: </strong>Diabetic retinopathy is a major cause of blindness worldwide. The associated loss of productivity and quality of life of the patients with diabetic retinopathy will lead to additional socioeconomic burden. This study aims to determine the level of awareness of diabetic retinopathy among diabetic patients. <strong></strong></p><p><strong>Materials and Methods: </strong>This hospital-based cross sectional study, was carried out at the Diabetic and Ophthalmology clinics of University of Ilorin Teaching Hospital, Nigeria from November 2011 to July 2012. A total of 365<strong> </strong>patients had validated, semi-structured, and interviewer-administered questionnaires to obtain information on socio-demographic characteristics, clinical information and awareness of diabetic retinopathy. <strong></strong></p><p><strong>Results: </strong>A total of 365 patients were enrolled, with age between 19 and 90 years, and a mean of 45.8 ±16.3 years. The male to female ratio was 1: 2.2. Ninety-nine respondents (27.1%) had no education. The majority (30.4%) had only primary education; 21.1% had tertiary; 14.5% had secondary while 6.8% had Quranic education. The mean duration of diabetes mellitus was 14.1 ±13.09 years. Of the 365 patients with diabetes mellitus, 279(76.4%) had heard that diabetes mellitus affects the eyes, while 86(23.6%) had not. Of those who had heard, 221(79.2%) heard it from health personnel, 45(16.1%) from radio/television, 25(9.0%) from internet, 23(8.2%) from books/newspapers, while 16(5.7%) heard from other sources.<strong></strong></p><p><strong>Conclusion: </strong>There was a high level of awareness of diabetic retinopathy amongst the patients. However, the high level of awareness of the blinding complication of diabetes mellitus did not translate to a correspondingly high level of ocular examination for diabetic retinopathy.  <strong></strong></p>


Author(s):  
Khalid Mohammad Alabdulwahhab

Abstract Aim We compare the incidence rates of cataract in persons with diabetes with and without diabetic retinopathy in Saudi Arabia, for the first time. In addition, we explored the role of new factor, diabetes age of onset and several other known factors. Methods In a community-based cross-sectional study, 334 persons with diabetes type 2 were randomly selected from a diabetic register. Detailed history and comprehensive ophthalmic examination was done at an eye clinic. Body Mass Index, blood pressure and glycosylated hemoglobin were also recorded. Results In 668 eyes, cataract and diabetic retinopathy were present in 35.5% and 32.2%, respectively. Diabetic retinopathy, age, duration of diabetes and systolic BP were found to be independent risk factors for cataract. Whereas, gender, BMI, HbA1c use of insulin and diastolic BP have no significant association with cataract. Persons with cataract had significantly higher age of onset of diabetes. Most of the cataracts were cortical followed by PSC, while minority were nuclear. Conclusion DR is an independent risk factor of developing cataract in persons with diabetes. Others are age, duration of DM and hypertension. Age-of-onset of DM is a new factor we report it to be significantly associated with cataract.


2020 ◽  
Author(s):  
Luis Jesuino de Oliveira Andrade ◽  
Caroline Santos Franca ◽  
Rafael Andrade ◽  
Alcina Maria Vinhaes Bittencourt ◽  
Gabriela Correia Matos de Oliveira

Purpose: Employ fuzzy logic to auxiliary in identification and diagnosis the gravity of diabetic retinopathy (DR). Methods: A cross-sectional study was performed, being assessed 100 diabetes mellitus patients with DR. The following ultrasound findings were measured employing a semi-quantitative punctuation method: vitreous hemorrhage, posterior vitreous detachment, epiretinal fibrosis, retinal detachment. The fundus photography (FP) aspects evaluated for diagnosis of DR were at least four or more microaneurysms with or without hard or soft exudates, and neovascularization, graded using the Early Treatment of Diabetic Retinopathy Scale. With the combination between ultrasound punctuation and FP aspects through fuzzy logic, a classification for DR has been built. Results: Microaneurysms were the findings which presented the better interaction with the DR severity on ultrasound, while the hard exudates showed the minors estimation errors when compared to soft exudates. A classification for DR was suggested based on the 95% confidence interval of number of microaneurysms: mild group (< 24.6); moderately mild (24.6 - 48.0); moderate (48.1 - 64.5); moderately severe (64.6 - 77.0); severe (77.1 - 92.7); and very severe (> 92.7). Conclusion: By the fuzzy logic, a DR classification was constructed supported on number of microaneurysms measurement with a simple practical application. Keywords: Fuzzy logic; Ultrasound imaging; Fundus retinal image; Diabetic retinopathy; Diabetes mellitus.


Author(s):  
Tanvi Poy Raiturcar ◽  
Apika K. Sawant ◽  
Shreya S. Lotliker ◽  
Jagadish A. Cacodcar ◽  
Preksha P. Vernekar

Background: Diabetic retinopathy is one of the most common complication of diabetes with a prevalence of 7.3-25%. There have been several studies done in India to assess the knowledge and awareness on diabetes and diabetic retinopathy among patients with diabetes, however very few studies assessed knowledge, awareness and practices amongst patients with diabetic retinopathy.4-7 Besides, no such study was undertaken at Goa Medical College.Methods: A cross-sectional study was conducted among 100 consecutive diabetic retinopathy patients attending ophthalmology out-patient department (OPD) at Goa Medical College and Hospital. The patients were administered a pre-tested proforma to assess their level of awareness and attitudes and practices towards diabetes and diabetic retinopathy. Data was entered in Microsoft excel 2010; analysed using the SPSS version 22. Chi-square test was used as test of significance.Results: In our study, 58% were aware of the symptoms of diabetes. 15% were aware of the multiple complications. 35% had knowledge about only one test for detecting diabetes i.e. fasting blood sugar level. 22% had never heard about HbA1c. 49% were not aware that they had diabetic retinopathy. 76% felt it is important to continue medications even if blood sugar levels were normal. 62% were aware of the importance of exercise. 71% took their medications regularly, 72% checked their blood sugar regularly. There was a significant association between educational status and awareness and practices towards diabetes.Conclusions: The diabetic retinopathy patients in our study had a fair knowledge about diabetes and diabetic retinopathy. 


2021 ◽  
Vol 8 (2) ◽  
pp. 62-66
Author(s):  
Dr. Sneha Murade ◽  
Dr. Amrut Swami ◽  
Dr. Anil Singh ◽  
Dr. Vikas Khamkar ◽  
Dr. Shruti Swami

Introduction: The numbers of people affected with lifestyle related diseases are increasing every day, diabetes being one of the major contributors to the increasing morbidity and mortality in the world. Diabetic retinopathy is one the complications of diabetes which is thought to be associated with the duration of diabetes, we conducted this study to evaluate the same. Methods: This study was conducted at Department of Ophthalmology. Total 100 cases were selected for the study and patient data was collected and analysed. Duration of diabetes and its association with diabetic retinopathy was studied. Results: There were 62 males (62%), most of the participants were more than 60 years of age (54%). Majority of the patients had diabetes for 5 to 10 years (44%) followed by 1 to 5 years (34%) and 0 – 1 year (22%). On FFA examination, majority of the patients had no any diabetic retinopathy (52%) while rest 48 patients had retinopathy (48%). Significant association was seen between the duration of diabetes and presence of diabetic retinopathy. (p=0.002). Conclusion: We found a significant association between the duration of diabetes and diabetic retinopathy. It is important that in patients with diabetes who are not diagnosed as retinopathy by ophthalmoscopy, FFA should be done.


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