Effects of soybean phospholipid, chlorella phospholipid, and clofibrate on collagen and elastin synthesis in the aorta and on the serum and liver lipid contents in rats

1982 ◽  
Vol 36 (1) ◽  
pp. 99-106 ◽  
Author(s):  
Shusuke Hashimoto ◽  
Tamotsu Setoyama ◽  
Teruo Yokokura ◽  
Masahiko Mutai
Keyword(s):  
Liver Lipid ◽  
Lipid Contents ◽  
Soybean Phospholipid

scholarly journals Ethanol Extract of Fructus Schisandrae Decreases Hepatic Triglyceride Level in Mice Fed with a High Fat/Cholesterol Diet, with Attention to Acute Toxicity

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Si-Yuan Pan ◽  
Zhi-Ling Yu ◽  
Hang Dong ◽  
Chun-Jing Xiang ◽  
Wang-Fun Fong ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Liver Lipid ◽  
Ethanol Extract ◽  
Hepatic Triglyceride ◽  
High Fat ◽  
Lipid Contents ◽  
Fenofibrate Treatment ◽  
Hepatic Index ◽  
Therapeutic Protocols ◽  
Potential Use

Effects of the ethanol extract of Fructus Schisandrae (EtFSC) on serum and liver lipid contents were investigated in mice fed with high fat/cholesterol (HFC) diet for 8 or 15 days. The induction of hypercholesterolemia by HFC diet caused significant increases in serum and hepatic total cholesterol (TC) levels (up to 62% and 165%, resp.) and hepatic triglyceride (TG) levels (up to 528%) in mice. EtFSC treatment (1 or 5 g/kg/day for 7 days; from Day 1 to 7 or from Day 8 to 14, i.g.) significantly decreased the hepatic TG level (down to 35%) and slightly increased the hepatic index (by 8%) in hypercholesterolemic mice. Whereas fenofibrate treatment (0.1 g/kg/day for 7 days, i.g.) significantly lowered the hepatic TG level (by 61%), it elevated the hepatic index (by 77%) in hypercholesterolemic mice. Acute toxicity test showed that EtFSC was relatively non-toxic, with an LD50value of 35.63 ± 6.46 g/kg in mice. The results indicate that EtFSC treatment can invariably decrease hepatic TG in hypercholesterolemic mice, as assessed by both preventive and therapeutic protocols, suggesting its potential use for fatty liver treatment.

A study of the chemical binding of allyl isothiocyanate with thyroxine and of the effect of allyl isothiocyanate on lipid metabolism in the rat

1979 ◽  
Vol 57 (4) ◽  
pp. 385-389 ◽  
Author(s):  
A. Jabbar Muztar ◽  
Parvez Ahmad ◽  
Taufiqul Huque ◽  
S. J. Slinger
Keyword(s):  
Liver Lipid ◽  
Lipid Production ◽  
Young Male ◽  
Allyl Isothiocyanate ◽  
Liver Protein ◽  
Sprague Dawley ◽  
Chemical Binding ◽  
Lipid Contents

Two experiments were conducted with allyl isothiocyanate (AITC): one in vitro, to investigate the chemical binding of AITC with thyroxine (T4), tyrosine (Tyr), and leucine (Leu), and the other in vivo, to evaluate the effect of AITC on the blood clotting mechanism and on the protein and lipid contents of rat liver. The in vitro study, which used the techniques of ultraviolet spectroscopy and thin-layer chromatography, indicated the formation of a complex of AITC with T4 and Tyr but not with Leu. The presence of a phenyl ring with an OH group at the position para to the alanine side chain is suggested as a prerequisite for the chemical binding of AITC with amino acids. The in vivo experiment involved administration of AITC, T4, or the ALTC–T4 complex by the intraperitoneal route to young male Sprague–Dawley rats for 30 days. AITC exhibited a strong coagulant effect, which was seemingly mediated by the relatively high plasma phospholipid concentration. T4 and the AITC–T4 complex were without a significant effect on blood coagulation. AITC was without effect on liver protein but increased cholesterol, phospholipid, and total lipid contents markedly. The effect of T4 on the liver protein and lipids was not significant. The AITC-T4 complex caused a significant increase in the liver protein and an intermediate rise in the lipids compared with AITC. The increase in plasma and liver lipid concentrations caused by AITC was probably related to increased hepatic lipid production and decreased clearance of the circulating lipids.

scholarly journals Lactobacillus Paracasei NFRI 7415 Reduces Liver Lipid Contents in C57BL/6J Mice Fed a High-fat Diet

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Noriko Komatsuzaki ◽  
Yumiko Yamada ◽  
Yukihide Ueki ◽  
Jun Shima ◽  
Shunichi Morikawa
Keyword(s):  
High Fat Diet ◽  
Liver Lipid ◽  
Lactobacillus Paracasei ◽  
High Fat ◽  
Lipid Contents

Effects of Yogurt Supplemented with Fish Oil on Plasma Lipid and Glucose Concentrations, and Liver Lipid Contents in Mice

2008 ◽  
Vol 78 (3) ◽  
pp. 129-138 ◽  
Author(s):  
Higuchi ◽  
Shirai ◽  
Suzuki ◽  
Kawashima ◽  
Tamura
Keyword(s):  
Fish Oil ◽  
Total Cholesterol ◽  
Control Diet ◽  
Liver Lipid ◽  
Plasma Lipid ◽  
Diet Group ◽  
Plasma Total Cholesterol ◽  
Lipid Contents ◽  
Plasma Triacylglycerol ◽  
Hepatic Triacylglycerol

The aim of this study is to clarify the effects of yogurt supplemented with fish oil on plasma lipid and glucose concentrations, and hepatic lipid contents in mice. Male Crlj:CD-1 (ICR) mice were fed five experimental diets for 12 weeks. The experimental diets were as follows: without yogurt and fish oil (control diet); 10% (w/w) yogurt without fish oil [10% FO(–)]; 10% yogurt with fish oil [10% FO(+)]; 30% yogurt without fish oil [30% FO(–)]; 30% yogurt with fish oil [30% FO(+)]. Plasma triacylglycerol concentrations in the 10% FO(+) and 30% FO(–) groups were significantly lower than that in the control diet group (p < 0.05 and p < 0.05, respectively). Plasma total cholesterol and phospholipid concentrations were significantly lower in the 30% FO(+) group than in the control diet group (p < 0.005). Concentrations tended to be lower with supplementation with fish oil. Plasma glucose concentrations in the 10% FO(+) and 30% FO(+) groups were significantly lower than those in the control diet group (p < 0.005 and p < 0.01, respectively). Hepatic triacylglycerol and total cholesterol contents in the 30% FO(+) group were significantly lower than those in the control diet group (p < 0.05 and p < 0.005, respectively). These results suggest that plasma triacylglycerol and glucose concentrations are effectively decreased by supplementation of yogurt with fish oil.

scholarly journals EFFECTS OF DIETARY ADENINE ON GROWTH, LIPID SECRETION, AND LIVER LIPID CONTENT

2010 ◽  
Vol 10 (2) ◽  
pp. 251-255
Author(s):  
Yohanes Buang
Keyword(s):  
Body Weight ◽  
Fatty Acid ◽  
High Density Lipoprotein ◽  
Serum Lipid ◽  
Liver Lipid ◽  
Density Lipoprotein ◽  
Liver Weight ◽  
Lipid Secretion ◽  
Relative Liver Weight ◽  
Lipid Contents

The effects of dietary adenine on growth, lipid secretion, and liver lipid contents were studied. Rats were paired-fed 0.25 % adenine diet or a diet without adenine for 10 days. The final body weight and relative liver weight were recorded. Serum lipid profiles were measured using enzyme assay kits. Lipids of liver tissues were extracted and the lipid contents were determined. A peach of liver was prepared to determine the activities of fatty acid synthase (FAS) and fatty acid β-oxidation. The results showed that animals fed an adenine diet reduced slightly body weight and relative liver weight and promoted serum triglyceride (TG), phospholipids (PL), total cholesterol, and high density lipoprotein concentrations. Their promotions were approximately by 74%, 20%, 27%, and 27%, respectively. The liver PL content increased significantly whereas the promotions of liver TG and cholesterol failed to reach significant level. Furthermore, the FAS activity slightly stimulated, but fatty acid β-oxidation significantly decreased. In conclusion: dietary adenine suppressed slightly growth of body weight and relative liver weight but promoted secretion of lipid compounds from liver tissue into extra-hepatic and liver PL content. The enzyme activity of lipogenic was slightly stimulated whereas the lipolytic was significantly inhibited.   Keywords: adenine, serum lipid, triglyceride, high density lipoprotein, cholesterol

scholarly journals Dietary Combination of Fish Oil and Hemoglobin Hydrolysates Alters Serum and Liver Lipid Contents in Rat

2013 ◽  
Vol 04 (09) ◽  
pp. 86-93 ◽  
Author(s):  
Kenji Fukunaga ◽  
Noriko Yukawa ◽  
Ryota Hosomi ◽  
Toshimasa Nishiyama ◽  
Munehiro Yoshida
Keyword(s):  
Fish Oil ◽  
Liver Lipid ◽  
Lipid Contents

Salmon Protamine Decreases Serum and Liver Lipid Contents by Inhibiting Lipid Absorption in anIn VitroGastrointestinal Digestion Model and in Rats

2015 ◽  
Vol 80 (10) ◽  
pp. H2346-H2353 ◽  
Author(s):  
Ryota Hosomi ◽  
Kazumasa Miyauchi ◽  
Daiki Yamamoto ◽  
Hirofumi Arai ◽  
Toshimasa Nishiyama ◽  
...  
Keyword(s):  
Liver Lipid ◽  
Lipid Absorption ◽  
Lipid Contents
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