Psychological attributes of women who develop breast cancer: A controlled study

1975 ◽  
Vol 19 (2) ◽  
pp. 147-153 ◽  
Author(s):  
S. Greer ◽  
Tina Morris
2008 ◽  
Vol 26 (33) ◽  
pp. 5374-5379 ◽  
Author(s):  
V. Shane Pankratz ◽  
Lynn C. Hartmann ◽  
Amy C. Degnim ◽  
Robert A. Vierkant ◽  
Karthik Ghosh ◽  
...  

Purpose An accurate estimate of a woman's breast cancer risk is essential for optimal patient counseling and management. Women with biopsy-confirmed atypical hyperplasia of the breast (atypia) are at high risk for breast cancer. The Gail model is widely used in these women, but has not been validated in them. Patients and Methods Women with atypia were identified from the Mayo Benign Breast Disease (BBD) cohort (1967 to 1991). Their risk factors for breast cancer were obtained, and the Gail model was used to predict 5-year–and follow-up–specific risks for each woman. The predicted and observed numbers of breast cancers were compared, and the concordance between individual risk levels and outcomes was computed. Results Of the 9,376 women in the BBD cohort, 331 women had atypia (3.5%). At a mean follow-up of 13.7 years, 58 of 331 (17.5%) patients had developed invasive breast cancer, 1.66 times more than the 34.9 predicted by the Gail model (95% CI, 1.29 to 2.15; P < .001). For individual women, the concordance between predicted and observed outcomes was low, with a concordance statistic of 0.50 (95% CI, 0.44 to 0.55). Conclusion The Gail model significantly underestimates the risk of breast cancer in women with atypia. Its ability to discriminate women with atypia into those who did and did not develop breast cancer is limited. Health care professionals should be cautious when using the Gail model to counsel individual patients with atypia.


Heliyon ◽  
2021 ◽  
pp. e08252
Author(s):  
Valentina Natalucci ◽  
Francesco Lucertini ◽  
Luciana Vallorani ◽  
Giorgio Brandi ◽  
Manuela Marchegiani ◽  
...  

2021 ◽  
Vol 9 (1) ◽  
pp. 1116-1122
Author(s):  
N. Dhanalakshmi, S. Satheesbabu, A. Thomas Paul Roy

Breast cancer is the most diagnosed and the leading cause of death in women. among women is breast cancer. Between 1 in 8 and 1 in 12 women in the developed world will experience breast cancer throughout their lives. The risk of breast cancer is of two primary types. The first type is that a person is likely to develop breast cancer over a specified time period. The second type reflects the likelihood of a high-risk gene mutation. Earlier work has shown that it has been better to predict the risk of breast cancer by adding input into the wide-spread Gail model. The main objective is to predict analytics model to diagnose breast cancer stages of patients. The main objective of this work is to detect and analyze breast cancer. It predicts the stages of the cancer and gives as the accurate result. In this work, to investigate a dataset of medical patient records for hospital sector using machine learning technique and to identify patients having breast cancer stages from given dataset attributes. Then the accurate result is found by naive Bayesian algorithm with precision, recall, F1score.


Mastology ◽  
2020 ◽  
Vol 30 (Suppl 1) ◽  
Author(s):  
Marina Hernandes Carvalho ◽  
Pedro César Garcia Gonçalves ◽  
Gabriel Carvalho Carnelossi ◽  
Maria Júlia Carvalho Carnelossi ◽  
Felipe Colombelli Pacca

Introduction: Screening and early diagnosis are crucial strategies for the detection of breast cancer. In Brazil, the Ministry of Health recommends annual clinical screening in women over 40 years of age, with the addition of biennial mammography for those aged between 50 and 69 years. However, high-risk patients should have mammography annually after the age of 35 years. Objectives: To study the reasons for mammography screening in the age group 50 to 69 years. Method: This is an ecological study of the number of patients per mammography report according to age group, from 2015 to 2019. Data from the Cancer Information System (Sistema de Informação do Câncer – SISCAN) were obtained from the Technology Department of the public health system (Departamento de Informática do Sistema Único de Saúde – DATASUS). Results: When comparing data from the Breast Cancer Information System (Sistema de Informação do Câncer de Mama – SISMAMA) from 2015 to 2019, we found 8,569,457 mammographies, of which 5,216,473 were performed in women aged 50 years to 69 years, which corresponds to 60.87% of the procedures. In addition, 4.90% of these women were high-risk individuals, and 1.24% had been treated for breast cancer. Mammography reports showed that 12.01% of the results were inconclusive, 38.28% were normal, 46.12% had a benign radiological finding, 2.58% had a probably benign finding, 0.78% had a suspicious finding, 0.14% had a highly suspicious finding, and 0.04% had malignant confirmation. The proportion of BI-RADS categories 4, 5, and 6 totaled 83,852 screenings, the equivalent to 0.97% of reports. In addition, 59.49% (49,891) of women who presented mammographic findings with malignant characteristics belonged to the age group 50–69 years. Conclusion: This study concluded that the strategy of biennial breast cancer screening shows scientific evidence of mortality reduction, given that 59.49% of the reports with malignant characteristics corresponded to the age group 50 to 69 years. However, the data presented did not allow calculating the number of women outside this age group who do not receive care and develop breast cancer.


2017 ◽  
Vol 4 (8) ◽  
pp. 2397 ◽  
Author(s):  
Ahmed Gaber ◽  
Ahmed Fawzy ◽  
Ahmed Sabry ◽  
Alaa El sisi

Background: Breast cancer is one of the most leading causes of cancer deaths in female. Surgical treatment is considered the corner stone in its management. Axillary lymph node dissection (ALND) is an integral step in most of surgeries done, however it has many morbidities like prolonged seroma and lymphedema. Axillary reverse mapping (ARM) procedure was first described in 2007 in a trial to map the axillary lymphatics of the arm and avoid its injury therefore lymph complications.Methods: A prospective, randomized, controlled study over 72 female patients who underwent modified radical mastectomy (MRM). Patients were divided and randomized into study and control groups, thirty-six patients for each. In study group the ARM procedure was done by injecting 2.5 ml of methylen blue dye intra-dermally and subcutaneously in the upper inner ipsilateral arm along the medial intramuscular groove before ALND. Operative and post-operative results were recorded. Follow up was 6 to 24 months.Results: ARM procedure and successful visualization of arm lymphatics was achieved in 31 patients (86.1%). Statistically there was no significant difference between the two groups regarding patient and tumour characteristics, operative time and number of excised L.Ns. There was significant difference favouring the ARM group in decreasing the incidence of seroma (p= 0.040), lymphedema (p= 0.031) and time passed till remove drains (p <0.001).Conclusions: ARM procedure facilitated arm lymphatics visualization. It is easy non-time-consuming procedure. It resulted in significant reduction in incidence of seroma and lymphedema, with considerable reduction in the overall complications rate.


1986 ◽  
Vol 24 (17) ◽  
pp. 65-67

About one in every fourteen women in Britain will develop breast cancer at some time, the risk increasing with age. Breast cancer has a long natural history and can still prove fatal up to 30 years after diagnosis. The median survival from first recurrence is less than 2 years, but the disease may progress very slowly and some patients may live for many years without treatment. New treatments in breast cancer can therefore be assessed only by randomized controlled trials which should preferably be long term. Tamoxifen has become widely used in the treatment of all stages of carcinoma of the breast. Its proven efficacy and minimal toxicity are now well established. This article assesses its contribution to the management of this common disease.


1992 ◽  
Vol 30 (14) ◽  
pp. 53-56

One in 12 women in Britain will develop breast cancer and in any one year 15000 women will die of the disease. Prognosis for patients with advanced breast cancer has altered little during the past 30 years, but for those diagnosed early outlook has improved. Greater public awareness coupled with a national screening programme has led more women to present at an early stage1 and gives them a greater opportunity to take advantage of improved management. In this, the first of two articles on breast cancer, we discuss developments in the management of early disease. A later article will examine the follow-up of patients with breast cancer.


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