Acute effects of ethanol and acetaldehyde on blood pressure and heart rate in disulfiram-treated and control rats

1982 ◽  
Vol 17 (6) ◽  
pp. 1103-1109 ◽  
Author(s):  
Ewa Hellström ◽  
Olof Tottmar
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Acute Effects ◽  
And Control

scholarly journals THE EFFECTS OF STRETCHING EXERCISE ON HEMODYNAMIC RESPONSES AND POST-EXERCISE HYPOTENSION IN NORMOTENSIVE WOMEN STUDENTS

2014 ◽  
Vol 18 (5) ◽  
pp. 53-58
Author(s):  
Mohebbi Hamid ◽  
Maroofi Abdulbaset ◽  
Ansari Nazanin ◽  
Jorbonian Aboozar
Keyword(s):  
Blood Pressure ◽  
Women Students ◽  
Young Women ◽  
Whole Body ◽  
Rate Pressure Product ◽  
Rest Interval ◽  
Acute Effects ◽  
Hemodynamic Responses ◽  
Post Exercise ◽  
And Control

Aim: The aim of the present study was to evaluate acute effects of SE on post-exercise hemodynamic responses for 1-h in normotensive sedentary young women. Methods: Sixteen women (21.56±1.21yr; 159.6±0.5 cm; 54.53±6.02 kg) were randomly assigned to SE (n = 8) and control (C) groups (n = 8). SE group performed 20 stretches for the whole body. Each SE was repeated 2 times. Rest interval between repetitions and movement 10 s were considered. Systolic blood pressure (SBP), diastolic BP (DBP), mean arterial BP (MAP), rate pressure product (RPP), pulse pressure (PP) and heart rate (HR) were measured during 1-h (minutes: 0,15,30,45 and 60) in SE and C groups. Results: There were significant decreases (P

The effect of Adrenaline upon Cardiovascular and Metabolic Functions in Man

1985 ◽  
Vol 69 (2) ◽  
pp. 215-222 ◽  
Author(s):  
I. W. Fellows ◽  
T. Bennett ◽  
I. A. Macdonald
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Metabolic Rate ◽  
Plasma Potassium ◽  
Glycerol Concentration ◽  
Plasma Adrenaline ◽  
Metabolic Functions ◽  
Circulatory Effects ◽  
Solution Saline ◽  
And Control

1. On three separate occasions, at least 1 week apart, seven young healthy male subjects received intravenous infusions of either adrenaline, 50 ng min−1 kg−1 (high A), adrenaline, 10 ng min−1 kg−1 (low A) or sodium chloride solution (saline :154 mmol of NaCl/1) plus ascorbic acid, 1 mg/ml (control), over 30 min. 2. Venous adrenaline concentrations of 2.19 ± 0.15 nmol/l, 0.73 ± 0.08 nmol/l and 0.15 ± 0.03 nmol/l were achieved during the high A, low A and control infusions respectively. 3. Heart rate rose significantly by 19 ± 3 beats/min (high A) and by 6 ± 1 beats/min (low A). Heart rate remained significantly elevated 30 min after cessation of the high A infusion, despite venous plasma adrenaline concentration having fallen to control levels. 4. The diastolic blood pressure fell during the high A and low A infusions, but the systolic blood pressure rose only during the high A infusion. 5. Vasodilatation occurred in the calf vascular bed during both high A and low A infusions. The changes in hand blood flow and hand vascular resistance were not statistically significant, although there was a tendency to vasoconstriction during the infusion of adrenaline. 6. Metabolic rate rose significantly by 23.5 ± 1.8% (high A) and by 11.8 ± 1.6% (low A). Metabolic rate remained elevated between 15 and 30 min after termination of the high A infusion. There was an initial transient increase in respiratory exchange ratio (RER) during the adrenaline infusions. During the later stages of the adrenaline infusions and after their cessation, RER fell, probably reflecting increased fat oxidation. 7. Blood glucose, glycerol and lactate concentrations all rose significantly during the high A infusion, but only the blood glycerol concentration rose during the low A infusion. Plasma potassium concentration fell during and after the high A infusion but only after cessation of the low A infusion. 8. When adrenaline was infused intravenously at rates that elevated the plasma adrenaline concentration within the physiological range, peripheral circulatory effects were observed similar to those previously described for larger doses of adrenaline. The persistent tachycardia noted after stopping the high A infusion may, at least in part, have been a consequence of the concomitantly elevated metabolic rate.

Cardiovascular and Autonomic Reflexes in Haemodialysis Patients

1981 ◽  
Vol 60 (2) ◽  
pp. 165-170 ◽  
Author(s):  
R. B. Naik ◽  
C. J. Mathias ◽  
C. A. Wilson ◽  
J. L. Reid ◽  
D. J. Warren
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Plasma Noradrenaline ◽  
Valsalva Manoeuvre ◽  
Induced Hypotension ◽  
Autonomic Nervous ◽  
Control Subjects ◽  
Head Up Tilt ◽  
And Control ◽  
Noradrenaline Levels

1. Blood pressure and heart rate responses to head-up tilt, standing, the Valsalva manoeuvre, sustained handgrip and cutaneous cold were measured in 27 haemodialysis patients (10 of whom had episodes of haemodialysis-induced hypotension) and 15 control subjects to assess autonomic nervous function. Plasma nor-adrenaline levels were measured at rest and during head-up tilt. 2. Mean resting supine blood pressure, heart rate and plasma noradrenaline levels were higher in haemodialysis patients than in the control subjects. There was no fall in blood pressure during head-up tilt or standing. The ratio of the R-R intervals of the thirtieth and the fifteenth heart beat after standing (30: 15) was lower in the patients; this may be related to their higher resting heart rate. Head-up tilt raised plasma noradrenaline levels in both groups. Heart rate responses to the Valsalva manoeuvre were similar in the patients and control subjects. 3. Systolic blood pressure and heart rate responses to sustained handgrip were similar in both groups. Diastolic and mean blood pressure changes, however, were lower in the patients. The blood pressure and heart rate responses to cutaneous cold were similar in the patients and control subjects. 4. We conclude that generalized autonomic nervous dysfunction does not appear to cause haemodialysis-induced hypotension in patients with chronic renal failure on maintenance haemodialysis.

Renal extraction and acute effects of glucagon-like peptide-1 on central and renal hemodynamics in healthy men

2015 ◽  
Vol 308 (8) ◽  
pp. E641-E649 ◽  
Author(s):  
Ali Asmar ◽  
Lene Simonsen ◽  
Meena Asmar ◽  
Sten Madsbad ◽  
Jens J. Holst ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Cardiac Output ◽  
Filtration Rate ◽  
Renal Plasma Flow ◽  
Renal Hemodynamics ◽  
Acute Effects ◽  
Primary Metabolite ◽  
Healthy Men ◽  
Glucagon Like Peptide

The present experiments were performed to elucidate the acute effects of intravenous infusion of glucagon-like peptide (GLP)-1 on central and renal hemodynamics in healthy men. Seven healthy middle-aged men were examined on two different occasions in random order. During a 3-h infusion of either GLP-1 (1.5 pmol·kg−1·min−1) or saline, cardiac output was estimated noninvasively, and intraarterial blood pressure and heart rate were measured continuously. Renal plasma flow, glomerular filtration rate, and uptake/release of hormones and ions were measured by Fick's Principle after catheterization of a renal vein. Subjects remained supine during the experiments. During GLP-1 infusion, both systolic blood pressure and arterial pulse pressure increased by 5 ± 1 mmHg ( P = 0.015 and P = 0.002, respectively). Heart rate increased by 5 ± 1 beats/min ( P = 0.005), and cardiac output increased by 18% ( P = 0.016). Renal plasma flow and glomerular filtration rate as well as the clearance of Na+ and Li+ were not affected by GLP-1. However, plasma renin activity decreased ( P = 0.037), whereas plasma levels of atrial natriuretic peptide were unaffected. Renal extraction of intact GLP-1 was 43% ( P < 0.001), whereas 60% of the primary metabolite GLP-1 9-36amide was extracted ( P = 0.017). In humans, an acute intravenous administration of GLP-1 leads to increased cardiac output due to a simultaneous increase in stroke volume and heart rate, whereas no effect on renal hemodynamics could be demonstrated despite significant extraction of both the intact hormone and its primary metabolite.

scholarly journals Acupuncture on Lactate, Perceived Exertion in Recreational Athletes Submitted to HIIT

2020 ◽  
Author(s):  
Carlos Soares Pernambuco ◽  
Rodrigo Gomes de Souza Vale ◽  
João Rafael Valentim-Silva ◽  
Carlos Alberto de Souza Filho ◽  
Vinicius do Espirito Santo de Jesus ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Perceived Exertion ◽  
Pearson Correlation ◽  
Acupuncture Points ◽  
Acute Effects ◽  
Recreational Athletes ◽  
Positive Effects ◽  
Activity Intensity ◽  
Lactate Levels

Studies have demonstrated the positive effects of acupuncture on athletic performance. The aim of this study was to determine the acute effects of acupuncture on heart rate, the perceived exertion scale and lactate levels in recreational athletes. Fifteen competitive males engaged in HIIT. The characteristic was 29.86&plusmn;2.51 years old, heart rate reserve 59.00&plusmn;3.33, lactate 3.17&plusmn;0.50 mM/DL. The subjects were submitted to two exercise sessions. Both training sessions consisted of 10 burpees, 12 thrusters and 14 box jumps (75 cm high) for 12 minutes. Activity intensity was between 85 and 95% of maximum heart rate. Acupuncture points: ST36, L3, LI11. The student&rsquo;s t-test was adopted, Shapiro-Wilk test was applied for normality, and Pearson correlation. There was a positive correlation of r = 0.69 between lactate levels and heart rate. Lactate: Lac1 15.00&plusmn;1.18 &ndash; Lac2 19.59&plusmn; 1.46 p= 0.0001*; Heart 1rate: HRF 163.71&plusmn;7.27 &ndash; HRF2 177.60&plusmn;6.99 p=0.0001*; Blood pressure: SBP1 174.86&plusmn;1.57 &ndash; SBP2 180.86&plusmn;1.77 p= 0.0001*; PES1: 19.4&plusmn;1.14; PES2 16.8&plusmn;0.84 p= 0.0001*; weight1 &ndash; 182,57&plusmn;12,05; weight 2 206,43&plusmn;11,39 p=0.0325*. Acupuncture increased lactate accumulation, heart rate and blood pressure, suggesting that the exertion reached after acupuncture is higher than without acupuncture. The acupuncture technics improved the athlete performance.

scholarly journals Meta-analysis of trimetazidine treatment for cardiomyopathy

2018 ◽  
Vol 38 (3) ◽  
Author(s):  
Qian Fan ◽  
Zhaozhuo Niu ◽  
Liqing Ma
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Publication Bias ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Cochrane Library ◽  
Control Group ◽  
Ventricular Ejection Fraction ◽  
And Control

To explore the effect of trimetazidine (TMZ) in cardiomyopathy treatment. Literatures, related with TMZ treatment for cardiomyopathy, were retrieved between 1990 and February 2018 in the Pubmed, Embase, and Cochrane Library systems. Cardiopulmonary exercise testing [resting heart rate (RHR), peak heart rate (PHR), peak systolic blood pressure (PSBP), and resting systolic blood pressure (RSBP)] and echocardiographic results [left ventricular ejection fraction (LVEF), left ventricular end-systolic volume (LVESV), left ventricular end-diastolic volume (LVEDV), systolic wall thickening score index (SWTSI), left ventricular end-systolic diameter (LVESD), and left ventricular end-diastolic diameter (LVEDD)] were merged to detect the publication bias. Total 898 patients with cardiomyopathy were divided into two groups: TMZ-treated group (n=456) and control group (n=442). There was no difference in the improvement of cardiomyopathy between the TMZ and control group. No publication bias was shown for PHR (t= 0.9791, P=0.5067). There were significant differences in LVEF, LVESV, SWTSI, LVESD, and LVEDD between the TMZ group and the control group. TMZ-treatment significantly increased the level of LVEF (95% confidence interval (CI): 5.46–7.84, P<0.001), and reduced the level of LVESV (95% CI: −18.73 to −7.77, P<0.001), SWTSI (95% CI: −0.47 to −0.15, Z = −3.85, P=0.001), LVESD (95% CI: −1.09 to −0.08, P<0.001), and LVEDD (95% CI: −0.55 to −0.26, P=0.023). There was no publication bias except for LVEDV (t = 2.5456, P=0.0438). TMZ is effective for cardiomyopathy treatment and worth to popularize in clinic.

Acute effects of waterpipe smoking on blood pressure and heart rate: a real-life trial

2016 ◽  
Vol 28 (8) ◽  
pp. 339-342 ◽  
Author(s):  
Rabih R. Azar ◽  
Antonio H. Frangieh ◽  
Jad Mroué ◽  
Lilliane Bassila ◽  
Mohamad Kasty ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Real Life ◽  
Waterpipe Smoking ◽  
Acute Effects
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