The modular structure of informational sequences

Biosystems ◽  
1996 ◽  
Vol 37 (3) ◽  
pp. 199-210 ◽  
Author(s):  
Armin O. Schmitt ◽  
Werner Ebeling ◽  
Hanspeter Herzel
Keyword(s):  
2015 ◽  
Vol 43 (5) ◽  
pp. 844-849 ◽  
Author(s):  
Rocío Espada ◽  
R. Gonzalo Parra ◽  
Manfred J. Sippl ◽  
Thierry Mora ◽  
Aleksandra M. Walczak ◽  
...  

Structural domains are believed to be modules within proteins that can fold and function independently. Some proteins show tandem repetitions of apparent modular structure that do not fold independently, but rather co-operate in stabilizing structural forms that comprise several repeat-units. For many natural repeat-proteins, it has been shown that weak energetic links between repeats lead to the breakdown of co-operativity and the appearance of folding sub-domains within an apparently regular repeat array. The quasi-1D architecture of repeat-proteins is crucial in detailing how the local energetic balances can modulate the folding dynamics of these proteins, which can be related to the physiological behaviour of these ubiquitous biological systems.


IEEE Access ◽  
2021 ◽  
pp. 1-1
Author(s):  
Gustavo F. Gontijo ◽  
Dezso Sera ◽  
Mattia Ricco ◽  
Laszlo Mathe ◽  
Tamas Kerekes ◽  
...  

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Louis Kang ◽  
Vijay Balasubramanian

Grid cells in the medial entorhinal cortex (MEC) respond when an animal occupies a periodic lattice of ‘grid fields’ in the environment. The grids are organized in modules with spatial periods, or scales, clustered around discrete values separated on average by ratios in the range 1.4–1.7. We propose a mechanism that produces this modular structure through dynamical self-organization in the MEC. In attractor network models of grid formation, the grid scale of a single module is set by the distance of recurrent inhibition between neurons. We show that the MEC forms a hierarchy of discrete modules if a smooth increase in inhibition distance along its dorso-ventral axis is accompanied by excitatory interactions along this axis. Moreover, constant scale ratios between successive modules arise through geometric relationships between triangular grids and have values that fall within the observed range. We discuss how interactions required by our model might be tested experimentally.


2013 ◽  
Vol 56 (1) ◽  
Author(s):  
Leonardo Sagnotti

<p>The Demagnetization Analysis in Excel (DAIE) software is a single Microsoft Excel file designed for viewing and analyzing stepwise demagnetization data of both discrete and u-channel samples in paleomagnetic studies. DAIE is an Excel workbook and has an open modular structure organized in 10 worksheets. It is designed for an easy use and an interactive operability; all the commands and choices can be entered by sliding menus associated to single cells. The standard demagnetization diagrams and various parameters of common use are shown on the same worksheet including selectable parameters and user's choices. The remanence characteristic components may be computed by principal component analysis (PCA) on a selected interval of demagnetization steps. Saving of the PCA data can be done both sample by sample, or in automatic by applying the selected choices to all the samples included in the file. The whole workbook is free both for use and editing and it is available for download on a dedicated website.</p>


2003 ◽  
Vol 4 (4) ◽  
pp. 222-227
Author(s):  
Oleg Zaikine ◽  
Emma Kushtina ◽  
Przemyslaw Rozewski

The authors discuss the method of designing the distance learning didactic materials for the asynchronous mode. The approach is based on the modular structure of the fundamental knowledge. The new role of the teacher is being discussed as well as its impact on the didactic materials’ structure and content. The paper introduces the knowledge representation model designed to meet the requirements of theoretical knowledge presentation in a selected domain using the Learning Object concept.


Author(s):  
S.V. KHUDIK ◽  
◽  
D.A. ZAVYALOV ◽  

Statement of the problem. Today, when the epidemic raises specific requirements to the sanitary standards, teachers of the Physical Culture and Sports discipline need to take the maximum use of open spaces for their classes. The most common exercises for the autumn and spring periods of the academic year are cross-country running for different distances, general and strength development exercises in outdoor sports grounds. During the stable snow cover period, physical education focuses on ski training. Such activities have been always used as a perfect way of preventing respiratory diseases and virus infections. The problem and the task set before the teaching staff is support and stimulation of the students’ interest to outdoor training all year round, since only regular practice combined with knowledge in the sphere of physical culture and sports may develop a need for physical activity in the future. In this situation, it appears natural to add orienteering in the areas adjacent to the ski stadiums to the Physical Culture and Sports classes. The purpose of the article is to develop a modular structure for building the program of the Physical Culture and Sports discipline for students of non-physical culture profile during year-round outdoor activities using orienteering means, ski and general physical training. The methodology of the research includes the basic principles of physical education at higher educational institutions, methodological basics of physical development through ski training at the student age, the basics of embedding orienteering into the physical education process, analysis and generalization of the academic publications dedicated to the practical implementation of the Physical Culture and Sports discipline at higher educational institutions. The research results allow us to state that the application of the modular structure of the program of the Physical Culture and Sport academic discipline on the basis of two kinds of sports – ski training and orienteering, as well as the block of general physical training, which is mandatory in all training programs on this discipline is a more effective form for the implementation of this academic discipline. As a result of introducing this block structure there was an increase in the average attendance of physical education classes by students of the experimental group in the autumn semester from 74.56 ± 3.78 to 88.24 ± 4.62, in the spring the numbers increased by 13-14% (p <0.05), namely, from 76.23 ± 4.15 to 89.15 ± 4.44. The results of strength tests from the Physical Traning Standards (GTO) complex also significantly increased owing to the concentration of general physical training on a specially selected block, where these exercises were performed with multiple effortful repetitions not exceeding 30% – 40% of the possible individual maximum. In the ski training block, the students of the experimental group, on average, in each lesson were able to walk longer distance, longer by 29% by boys and by 32% by girls compared to the students of the control group. Orienteering block in autumn and spring allows students to fully master the competitive exercise in this sport. Conclusion. The designed block-based structure may be recommended for implementation in the training program among university students majoring in non-sport subjects with access to skiing centers equipped with skiing tracks and some mapped forest area. This is especially relevant in the difficult epidemiological situation in the country when the need for open-air training among students complying with all the applicable sanitary standards becomes extremely acute.


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