Clustering and six year cluster-tracking of serum total cholesterol, HDL-cholesterol and diastolic blood pressure in children and young adults The cardiovascular risk in young finns study

1994 ◽  
Vol 47 (10) ◽  
pp. 1085-1093 ◽  
Author(s):  
Olli T. Raitakari ◽  
Kimmo V.K. Porkka ◽  
Leena Räsänen ◽  
Tapani Rönnemaa ◽  
Jorma S.A. Viikari
Keyword(s):  
Blood Pressure ◽  
Young Adults ◽  
Cardiovascular Risk ◽  
Total Cholesterol ◽  
Diastolic Blood Pressure ◽  
Hdl Cholesterol ◽  
Serum Total Cholesterol ◽  
Children And Young Adults ◽  
Cluster Tracking ◽  
Young Finns Study

scholarly journals Dietary fibres reduce blood pressure, serum total cholesterol and platelet aggregation in rats

1996 ◽  
Vol 75 (3) ◽  
pp. 483-493 ◽  
Author(s):  
M. Bagger ◽  
O. Andersen ◽  
J.B. Nielsen ◽  
K.R. Ryttig
Keyword(s):  
Blood Pressure ◽  
Platelet Aggregation ◽  
Total Cholesterol ◽  
Diastolic Blood Pressure ◽  
Dietary Fat ◽  
Dietary Fibre ◽  
Dietary Habits ◽  
Serum Total Cholesterol ◽  
Dietary Fibres ◽  
Fat Reduction

AbstractThe effects of dietary fat and dietary fibres on blood pressure, serum lipids and platelet aggregation in spontaneously hypertensive and Wistar-Kyoto rats have been investigated. The systolic and diastolic blood pressure values were increased with increasing amounts of dietary fat and normalized by dietary fibre supplementation. The greatest reduction in blood pressure was obtained by a combination of reduced dietary fat and supplementary dietary fibre. Addition of dietary fibre when the amount of dietary fat was high or reduction of dietary fat when the amount of dietary fibre was low gave a smaller effect. In both rat strains the decreases in systolic and diastolic blood pressure values after reducing dietary fat and/or increasing dietary fibre were about 10-15 mmHg. Serum total cholesterol and serum HDL-cholesterol concentrations were reduced by reduction of dietary fat or a combination of dietary fat reduction and dietary fibre addition. A combination of dietary fat reduction and dietary fibre addition was the most effective dietary change for reducing serum triacylglycerol concentration and platelet aggregation. The present study demonstrates that in this experimental model it is possible to reduce risk indicators of coronary heart disease significantly by changing dietary habits.

scholarly journals Cardiovascular Risk Factors in Adult Javanese Patients with Hemophilia A

2021 ◽  
Author(s):  
Faizal Muhammad
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Uric Acid ◽  
Cardiovascular Risk ◽  
Total Cholesterol ◽  
Cardiovascular Risk Factors ◽  
Diastolic Blood Pressure ◽  
Hemophilia A ◽  
Mean Values ◽  
Significant Difference

Hemophilia usually presents as bleeding after minor trauma or as a spontaneous bleed due its hypocoagulable state. Hemophilia A represents 80-85% of the total hemophilia population with a prevalence of 1:10,000. Cardiovascular risk factors were common in the general population compared with hemophilia patients. This study aims to identify cardiovascular risk factors in adult Javanese patients with hemophilia A and their relationship with hemophilia severity. This cross-sectional study involved registered Javanese race male patients at Dr. Moewardi General Hospital from November 2019 - April 2020. There are 76 hemophilia A patients, after excluding patients with other comorbidities, non-Javanese race and age >18 years old, 33 appropriate patients were then randomized. The study group consists of 30 patients with hemophilia A and 30 non-hemophilia patients. Data were collected once during patient visits to the hospital polyclinic. The collected data were body mass index (BMI), blood pressure, fasting blood sugar (FBS), total cholesterol, and uric acid. They were analyzed using the Spearman rank test. Median values of BMI scores were 20.82 (13.67-41.52) kg/m² for hemophilia A group and 24.67 (9.38-53.32) kg/m² for the control group (p < 0.05). Further, median values of diastolic blood pressure, the median of FBS, and mean values of the uric acid level also showed a significant difference (p < 0.05). Otherwise, the mean values of systolic blood pressure and median values of total cholesterol showed no significant difference. The BMI score, diastolic blood pressure, fasting blood sugar, and uric acid appear to be significant cardiovascular risk factor profiles in Javanese adult patients with hemophilia A. Hence, there must be a consideration, screening, and treatment for the cardiovascular risk factors in hemophilia A patients. Although the other studies are not sufficient to show recommended therapeutic targets and the results of reducing cardiovascular risk factors in hemophilia patients.

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