Development of radiation sterilization of medical products in China

Author(s):  
Zhou Ruiying ◽  
Jin Yongling
2021 ◽  
Vol 899 ◽  
pp. 172-178
Author(s):  
Rezeda Yu. Galimzyanova ◽  
Maria S. Lisanevich ◽  
Yuri N. Khakimullin

Radiation sterilization is widely used to sterilize nonwoven SMS medical products. SMS materials have improved filtering and barrier properties, low bacteriopermeability and, due to these properties, are indispensable for medicine. They are used to make such important health care products as disposable surgical clothing and underwear. As a result of the research carried out, the effect of gamma and electron radiation, in the range of absorbed doses from 15 to 25 kGy, on the strength characteristics of nonwoven SMS materials based on polypropylene with a surface density of 35, 40, 50 g/cm2 was studied. It has been established that the strength characteristics (tensile strength, tensile strength, and tear strength) of nonwoven materials decrease after exposure to ionizing radiation. The higher the density of the material, the more its characteristics decrease after radiation sterilization. It was also found that gamma radiation, due to its nature, has a stronger effect on nonwoven materials based on polypropylene, and leads to a stronger decrease in strength characteristics. In general, for products sterilized by ionizing radiation and made from SMS materials, it is important to control the strength characteristics, primarily, the tensile strength in the transverse direction of the web stuff.


1976 ◽  
Vol 10 (5) ◽  
pp. 701-703
Author(s):  
N. V. Ramkova ◽  
E. P. Pavlov ◽  
N. Yu. Prokazova ◽  
V. G. Yuzbashev ◽  
�. G. Tushov ◽  
...  

2019 ◽  
Vol 816 ◽  
pp. 328-332 ◽  
Author(s):  
M.S. Lisanevich ◽  
Elvina R. Rakhmatullina ◽  
Yu.N. Khakimullin ◽  
Rezeda Yu. Galimzyanova ◽  
R.M. Akhmadullin ◽  
...  

For polymeric materials intended for the manufacture of disposable sterile medical devices, resistance to sterilization methods is important. For the manufacture of disposable medical products is widely used polypropylene, destructive during radiation sterilization. It is established that the addition of polyquinone leads to a decrease in the destruction of polypropylene, which is manifested in a decrease in the values of the melt flow index and an increase in the degradation temperature of polypropylene of the irradiated compositions.


2020 ◽  
pp. 86-91
Author(s):  
M.I. Ayzatsky ◽  
K.Yu. Kramarenko ◽  
V.V. Mytrochenko

In this work we describe the procedure of estimation of regenerative beam blowup threshold current in an inhomogeneous accelerating section. The self-consistent problem of transverse motion of particles in the field of dipole mode excited by the beam is solved. The distribution of dipole field near the structure axis and the energy variation of beam particles were calculated before simulating the transverse dynamics. The threshold current for S-band industrial linac designed for radiation sterilization of medical products is estimated.


1983 ◽  
Vol 22 (3-5) ◽  
pp. 693-699
Author(s):  
C. Singson ◽  
C. Carmona ◽  
Z. de Guzman ◽  
W. Barrun ◽  
L. Lanuza

2020 ◽  
Vol 64 (11) ◽  
pp. 149-153
Author(s):  
Maria S. Lisanevich ◽  
◽  
Reseda Yu. Galimzyanova ◽  

As you know, laboratory-diagnostic glassware used in medicine is mainly made of polyethylene and polypropylene, transparent polystyrene and other polymers with the properties necessary for use in laboratory conditions. The advantages of plastic laboratory glassware are obvious: products made of it are lightweight, durable, besides, they do not react with urine of any acidity level and have no impurities. The presence of the label allows you to write the necessary data about the patient, which is also provided for by the instructions for sending the material to the laboratory. It is important for manufacturers that after sterilization the physical and mechanical indicators remain at a high level, and also the change in the color of the product turns out to be of no small importance. In the work, injection molded polypropylene grades were studied, which can be used as a material for laboratory-diagnostic glassware: Balen 01270, manufactured by JSC Ufaorgsintez, (PP 01270); Balen 1030, manufactured by JSC Ufaorgsintez, (PP 1030); H 250 GP / 3, produced by LLC Tobolsk-Polymer, Sibur Holding, (PP H 250 GP / 3); H 250, LLP "Company Neftekhim LTD", (PP 250). It was found that the greatest increase in MFI is observed for polypropylene of the Balen 1030 grade, increasing by 27.5 times. The smallest increase in MFI is observed for grades H 250 GP/3 and H 250 by 1.5-1.7 times. With an increase in the absorbed dose, the viscosity naturally increases due to the destruction of PP. The color practically does not change with an increase in the radiation dose. For PP H250. Recommended for manufacturers of medical devices PP H 250 grade polypropylene.


Author(s):  
K. Cowden ◽  
B. Giammara ◽  
T. Devine ◽  
J. Hanker

Plaster of Paris (calcium sulfate hemihydrate, CaSO4. ½ H2O) has been used as a biomedical implant material since 1892. One of the primary limiting factors of these implants is their mechanical properties. These materials have low compressive and tensile strengths when compared to normal bone. These are important limiting factors where large biomechanical forces exist. Previous work has suggested that sterilization techniques could affect the implant’s strength. A study of plaster of Paris implant mechanical and physical properties to find optimum sterilization techniques therefore, could lead to a significant increase in their application and promise for future use as hard tissue prosthetic materials.USG Medical Grade Calcium Sulfate Hemihydrate Types A, A-1 and B, were sterilized by dry heat and by gamma radiation. Types A and B were additionally sterilized with and without the setting agent potassium sulfate (K2SO4). The plaster mixtures were then moistened with a minimum amount of water and formed into disks (.339 in. diameter x .053 in. deep) in polyethylene molds with a microspatula. After drying, the disks were fractured with a Stokes Hardness Tester. The compressive strengths of the disks were obtained directly from the hardness tester. Values for the maximum tensile strengths σo were then calculated: where (P = applied compression, D = disk diameter, and t = disk thickness). Plaster disks (types A and B) that contained no setting agent showed a significant loss in strength with either dry heat or gamma radiation sterilization. Those that contained potassium sulfate (K2SO4) did not show a significant loss in strength with either sterilization technique. In all comparisons (with and without K2SO4 and with either dry heat or gamma radiation sterilization) the type B plaster had higher compressive and tensile strengths than that of the type A plaster. The type A-1 plaster however, which is specially modified for accelerated setting, was comparable to that of type B with K2SO4 in both compressive and tensile strength (Table 1).


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