Lean body mass and muscle strength as predictors of bone mass in young women

Bone ◽  
1995 ◽  
Vol 16 (3) ◽  
pp. 403
Author(s):  
O.R. Madsen ◽  
J. Micheelsen ◽  
J. Sylvest ◽  
O.H. Sørensen
2007 ◽  
Vol 10 (3) ◽  
pp. 319-326 ◽  
Author(s):  
Deborah Anne Kerr ◽  
Shona Papalia ◽  
Alan Morton ◽  
Ian Dick ◽  
Satvinder Dhaliwal ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Alexandra Aguilar-Perez ◽  
Rafael Pacheco-Costa ◽  
Emily G. Atkinson ◽  
Padmini Deosthale ◽  
Hannah M. Davis ◽  
...  

Abstract Pannexins (Panxs), glycoproteins that oligomerize to form hemichannels on the cell membrane, are topologically similar to connexins, but do not form cell-to-cell gap junction channels. There are 3 members of the family, 1–3, with Panx1 being the most abundant. All Panxs are expressed in bone, but their role in bone cell biology is not completely understood. We now report that osteocytic Panx1 deletion (Panx1Δot) alters bone mass and strength in female mice. Bone mineral density after reaching skeletal maturity is higher in female Panx1Δot mice than in control Panx1fl/fl mice. Further, osteocytic Panx1 deletion partially prevented aging effects on cortical bone structure and mechanical properties. Young 4-month-old female Panx1Δot mice exhibited increased lean body mass, even though pannexin levels in skeletal muscle were not affected; whereas no difference in lean body mass was detected in male mice. Furthermore, female Panx1-deficient mice exhibited increased muscle mass without changes in strength, whereas Panx1Δot males showed unchanged muscle mass and decreased in vivo maximum plantarflexion torque, indicating reduced muscle strength. Our results suggest that osteocytic Panx1 deletion increases bone mass in young and old female mice and muscle mass in young female mice, but has deleterious effects on muscle strength only in males.


Bone ◽  
2010 ◽  
Vol 46 ◽  
pp. S80
Author(s):  
Tom Sanchez ◽  
Jingmei Wang ◽  
Chad Dudzek ◽  
George Ekker ◽  
Kathy Dudzek

2012 ◽  
Vol 7 (4) ◽  
pp. 394-396 ◽  
Author(s):  
Gerasimos Terzis ◽  
Thomas Kyriazis ◽  
Giorgos Karampatsos ◽  
Giorgos Georgiadis

Purpose:Although muscle mass and strength are thought to be closely related to throwing performance, there are few scientific data about these parameters in elite shot-putters. The purpose of this case report was to present longitudinal data for muscle strength and body composition in relation to performance of an elite male shot-putter.Methods:A male national champion with the best rotational shot-put performance of 20.36 m (in 2010) was followed from 2003 to 2011 (current age: 29 y). Data regarding body composition (dual X-ray absorptiometry), as well as 1-repetition-maximum muscle strength (bench press, squat, snatch) and rotational shot-put performance, were collected every February for the last 9 y, 4 wk before the national indoor championship event.Results:The athlete’s personal-best performances in squat, bench press, and snatch were 175 kg, 210 kg, and 112.5 kg, respectively. His peak total lean body mass was 92.4 kg, bone mineral density 1.55 g/cm2, and lowest body fat 12.9%. His shot-put performance over these 9 years was significantly correlated with 1-repetition-maximum squat strength (r = .93, P < .01), bench press (r = .87, P < .01), and snatch (r = .92, P < .01). In contrast, shot-put performance was not significantly correlated with any of the body-composition parameters.Conclusions:The results of this case study suggest that elite rotational shot-put performance may not be directly correlated with lean body mass. Instead, it seems that it is closely related with measures of muscle strength.


2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Kristine Røren Nordén ◽  
Hanne Dagfinrud ◽  
Amund Løvstad ◽  
Truls Raastad

Introduction. The purpose of this study was to investigate body composition, muscle function, and muscle morphology in patients with spondyloarthritis (SpA).Methods. Ten male SpA patients (mean ± SD age39±4.1years) were compared with ten healthy controls matched for sex, age, body mass index, and self-reported level of physical exercise. Body composition was measured by dual energy X-ray absorptiometry. Musculus quadriceps femoris (QF) strength was assessed by maximal isometric contractions prior to test of muscular endurance. Magnetic resonance imaging of QF was used to measure muscle size and calculate specific muscle strength. Percutaneous needle biopsy samples were taken fromm. vastus lateralis.Results. SpA patients presented with significantly lower appendicular lean body mass (LBM) (p=0.02), but there was no difference in bone mineral density, fat mass, or total LBM. Absolute QF strength was significantly lower in SpA patients (p=0.03) with a parallel trend for specific strength (p=0.08). Biopsy samples from the SpA patients revealed significantly smaller cross-sectional area (CSA) of type II muscle fibers (p=0.04), but no difference in CSA type I fibers.Conclusions. Results indicate that the presence of SpA disease is associated with reduced appendicular LBM, muscle strength, and type II fiber CSA.


1993 ◽  
Vol 25 (Supplement) ◽  
pp. S101 ◽  
Author(s):  
M. A. Hallmark ◽  
T. H. Reynolds ◽  
C. A. DeSouza ◽  
C O. Dotson ◽  
R. A. Anderson ◽  
...  

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