THE USE OF A COMPUTATIONAL TOOL TO SUPPORT THE REFINEMENT OF IDEAS

Author(s):  
M.B. TWIDALE ◽  
T. RODDEN ◽  
I. SOMMERVILLE
Keyword(s):  

The choice of cost-effective method of anticorrosive protection of steel structures is an urgent and time consuming task, considering the significant number of protection ways, differing from each other in the complex of technological, physical, chemical and economic characteristics. To reduce the complexity of solving this problem, the author proposes a computational tool that can be considered as a subsystem of computer-aided design and used at the stage of variant and detailed design of steel structures. As a criterion of the effectiveness of the anti-corrosion protection method, the cost of the protective coating during the service life is accepted. The analysis of existing methods of steel protection against corrosion is performed, the possibility of their use for the protection of the most common steel structures is established, as well as the estimated period of effective operation of the coating. The developed computational tool makes it possible to choose the best method of protection of steel structures against corrosion, taking into account the operating conditions of the protected structure and the possibility of using a protective coating.


2014 ◽  
Vol 5 (2) ◽  
pp. 778-789
Author(s):  
Hassan Nouri Al-Obaidi ◽  
Ali A. Rashead Al-Azawy

Current research presents a visual-computational tool to design and investigate round electrostatic lenses in sense of analysis procedure. The finite elements methods is adopted to find the electrostatic potential in the lens region. Laplace’s equation is first replaced by a certain functional which physically represent the electric energy stored in the electric field. This functional is then minimized at each mesh point with respect to the nearest eight ones. This minimization process is proved to be entirely equivalent to solving Laplace’s equation. The requirement that the functional being minimized is then yields a set of nine point equations which inter relate the potentials at adjacent mesh points. Finally this set of equations is solved to find the electrostatic potential at each mesh point in the region of the lens under consideration. The procedure steps mention above are coded to program written in visual basic. Hence an interface tool for analyzing and designing electrostatic lenses has been built up. Designing results proved that the introduced tools has an excellent outputs in comparison with the others written in not visual programming languages. Furthermore it easier for researchers and designer to use such a tool over their counterpart ones.


Futures ◽  
2020 ◽  
Vol 123 ◽  
pp. 102607
Author(s):  
Pedro Ivo Garcia-Nunes ◽  
Pedro Artico Rodrigues ◽  
Kaulitz Guimarães Oliveira ◽  
Ana Estela Antunes da Silva

Author(s):  
E. Faghand ◽  
S. Karimian ◽  
E. Mehrshahi ◽  
N. Karimian

Abstract A new simple computational tool is proposed for the synthesis of multi-section coupled-line filters based on combined modified planar circuit method (MPCM) and transmission line method (TLM) analysis, referred to as MPCM-TLM. Due to its fundamentally simple architecture, the presented tool offers significantly faster optimization of coupled-line filters – for exactly the same initial simulation set-up – than other costly commercially-available tools, giving equally reliable results. Validity and accuracy of the proposed tool have been verified through the design of 3rd, 5th, and 7th order coupled-line filters and comparative analysis between results obtained from the proposed approach and the high-frequency structure simulator. A remarkable 99% time reduction in the analysis is recorded in the case of 7th order filter using the proposed tool, for almost identical results to HFSS. Therefore, it can be confidently claimed that the proposed technique can be used as a reliable alternative to existing complex, costly, processor-intensive CAD tools.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Prabina Kumar Meher ◽  
Anil Rai ◽  
Atmakuri Ramakrishna Rao

Abstract Background Localization of messenger RNAs (mRNAs) plays a crucial role in the growth and development of cells. Particularly, it plays a major role in regulating spatio-temporal gene expression. The in situ hybridization is a promising experimental technique used to determine the localization of mRNAs but it is costly and laborious. It is also a known fact that a single mRNA can be present in more than one location, whereas the existing computational tools are capable of predicting only a single location for such mRNAs. Thus, the development of high-end computational tool is required for reliable and timely prediction of multiple subcellular locations of mRNAs. Hence, we develop the present computational model to predict the multiple localizations of mRNAs. Results The mRNA sequences from 9 different localizations were considered. Each sequence was first transformed to a numeric feature vector of size 5460, based on the k-mer features of sizes 1–6. Out of 5460 k-mer features, 1812 important features were selected by the Elastic Net statistical model. The Random Forest supervised learning algorithm was then employed for predicting the localizations with the selected features. Five-fold cross-validation accuracies of 70.87, 68.32, 68.36, 68.79, 96.46, 73.44, 70.94, 97.42 and 71.77% were obtained for the cytoplasm, cytosol, endoplasmic reticulum, exosome, mitochondrion, nucleus, pseudopodium, posterior and ribosome respectively. With an independent test set, accuracies of 65.33, 73.37, 75.86, 72.99, 94.26, 70.91, 65.53, 93.60 and 73.45% were obtained for the respective localizations. The developed approach also achieved higher accuracies than the existing localization prediction tools. Conclusions This study presents a novel computational tool for predicting the multiple localization of mRNAs. Based on the proposed approach, an online prediction server “mLoc-mRNA” is accessible at http://cabgrid.res.in:8080/mlocmrna/. The developed approach is believed to supplement the existing tools and techniques for the localization prediction of mRNAs.


2021 ◽  
Vol 1 (5) ◽  
Author(s):  
Alberto Bettanti ◽  
Antonella Lanati

AbstractIn broad terms, risk management (RM) covers four conventional actions in addressing operational risks (OpRisks), i.e., actions to mitigate, eliminate, accept, and transfer operational risks. In relation to transferring OpRisks to external third parties, this study aids chief risk officers (CROs) in addressing issues related to the reduction of economic exposure to OpRisk. In this respect, the economic handling of OpRisks and their coverage through specific insurance programs are among the major challenges that CROs face within their roles. The aim of this paper is to provide CROs with an analytical pathway to addressing these challenges by applying the total cost of risk (TCoR) method tailored to their purposes. Through a leading example, this paper demonstrates that the TCoR approach meaningfully and productively supports CROs’ decisions when striving to deal with OpRisk. In fact, the TCoR approach implementation, together with the application of Monte Carlo simulation as a computational tool, drives TCoR value optimization when OpRisk is transferred to insurance agencies. In addition, by applying a TCoR framework, CROs can find the correct and cost-effective balance between the company’s retention level—consistent with the company’s risk appetite—and the premiums paid to insurance agencies. In conclusion, this paper provides CROs with a methodological approach for efficiently building relationships with insurance agencies by consistently addressing TCoR-based dealings.


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