Fatty acids from natural resources in inflammatory gastrointestinal diseases with specific focus on inflammatory bowel disease

2022 ◽  
pp. 121-135
Author(s):  
Marcin Talar ◽  
Aleksandra Tarasiuk ◽  
Maciej Salaga ◽  
Jakub Fichna
2021 ◽  
Vol 14 (1) ◽  
pp. e238802
Author(s):  
Fritz Ruprecht Murray ◽  
Bernhard Morell ◽  
Luc Biedermann ◽  
Philipp Schreiner

We report the case of a 63-year-old female patient with liver cirrhosis who presented with symptoms of severe hypoalbuminaemia and diarrhoea. After ruling out other causes of hypoalbuminaemia and confirmation of an elevated faecal α-1 antitrypsin clearance, the diagnosis of protein-losing enteropathy (PLE) could be established. Since PLE is a syndrome caused by various diseases, classified into erosive and non-erosive gastrointestinal diseases or lymphatic obstruction, an extensive work-up was necessary, establishing the final diagnosis of Crohn’s disease.


2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Chunxiang Ma ◽  
Reshma Vasu ◽  
Hu Zhang

Inflammatory bowel disease (IBD) is a complicated disease involving multiple pathogenic factors. The complex relationships between long-chain fatty acids (LCFAs) and the morbidity of IBD drive numerous studies to unravel the underlying mechanisms. A better understanding of the role of LCFAs in IBD will substitute or boost the current IBD therapies, thereby obtaining mucosal healing. In this review, we focused on the roles of LCFAs on the important links of inflammatory regulation in IBD, including in the pathogen recognition phase and in the inflammatory resolving phase, and the effects of LCFAs on immune cells in IBD.


2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Fanli Kong ◽  
Yi Cai

The gut microbiome in human is recognized as a “microbial organ” for its roles and contributions in regulating the human homeostasis and metabolism. Gastrointestinal (GI) cancers, especially colorectal cancer (CRC), rank as the most common cancer-related deaths worldwide. Evidences have suggested that the disorder of gut microbiota, also named as “dysbiosis,” is related to the development of a variety of diseases such as inflammatory bowel disease (IBD) and the CRC. However, detailed mechanisms between disease and gut microbiota remain largely unknown. This review introduced the correlation between gastrointestinal diseases and the microbiota in human gut from the recent studies, as well as the roles of microbiota in manipulating the CRC and IBDs development, in order to facilitate future studies and to develop novel methods for the precaution, diagnosis, or even cure of gastrointestinal diseases. Additionally, we also elucidated the possibility of probiotics in treatment against CRC.


2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Gheorghe Hundorfean ◽  
Stephen P. Pereira ◽  
John G. Karstensen ◽  
Peter Vilmann ◽  
Adrian Saftoiu

Endoscopy remains the most important diagnostic and monitoring modality in the management of inflammatory bowel disease. Advances in imaging have progressively added new tools into the armamentarium of endoscopists with the goal of more accurate, sensitive, and accessible visual diagnoses for the benefit of patients with gastrointestinal diseases. Here, we review the relevant literature regarding commonly used endoscopic techniques (dye-based and digital chromoendoscopy, high-definition endoscopy, capsule endoscopy, and endosonography), as well as advanced and experimental technologies (full-spectrum endoscopy, endocytoscopy, autofluorescence, laser endoscopy, and endomicroscopy, including molecular imaging), applicable to inflammatory bowel diseases and emerging for implementation into everyday practice. Additionally, we discuss future directions and techniques as candidates for a superior inflammation imaging in the diagnosis and prediction of therapeutic response.


2008 ◽  
Vol 27 (4) ◽  
pp. 571-578 ◽  
Author(s):  
Susanne Hengstermann ◽  
Luzia Valentini ◽  
Lennart Schaper ◽  
Carsten Buning ◽  
Thomas Koernicke ◽  
...  

2009 ◽  
Vol 15 (36) ◽  
pp. 4135-4148 ◽  
Author(s):  
C. Ruggiero ◽  
F. Lattanzio ◽  
F. Lauretani ◽  
B. Gasperini ◽  
C. Andres-Lacueva ◽  
...  

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Kelly Issokson

Lay Summary Research suggests that diet plays a role in the development of inflammatory bowel disease (IBD). Eating more fiber, omega-3 fatty acids, and limiting food additives may lower risk. More research is needed to better understand diet factors that may protect against IBD.


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