scholarly journals The relationship of Charlson comorbidity index and postoperative complications in elderly patients after partial or radical nephrectomy

2018 ◽  
Vol 24 (4) ◽  
pp. 387-391
Author(s):  
E. Becher ◽  
P.García Marchiñena ◽  
J. Jaunarena ◽  
D. Santillán ◽  
L. Pérez ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Elderly Patients ◽  
Charlson Comorbidity Index ◽  
Radical Nephrectomy ◽  
Comorbidity Index ◽  
Relationship Of ◽  
The Relationship

scholarly journals The relationship of Charlson comorbidity index with stent restenosis and extent of coronary artery disease

2018 ◽  
Vol 10 (2) ◽  
pp. 70-75 ◽  
Author(s):  
Turgut Karabağ ◽  
Emіne Altuntaş ◽  
Belma Kalaycı ◽  
Bahar Şahіn ◽  
Mustafa Umut Somuncu ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Charlson Comorbidity Index ◽  
Stent Restenosis ◽  
Comorbidity Index ◽  
Artery Disease ◽  
Relationship Of ◽  
The Relationship

scholarly journals Complications in the 90-day postoperative period following kidney transplant and the relationship of the Charlson Comorbidity Index

2017 ◽  
Vol 11 (12) ◽  
pp. 388-93 ◽  
Author(s):  
Max A. Levine ◽  
Trevor Schuler ◽  
Sita Gourishankar
Keyword(s):  
Logistic Regression ◽  
Postoperative Complications ◽  
Renal Transplant ◽  
Postoperative Period ◽  
Charlson Comorbidity Index ◽  
Significant Risk ◽  
Patient Counselling ◽  
Increased Risk ◽  
Comorbidity Index ◽  
Relationship Of

Introduction: Renal transplant experiences widespread success, but little is published regarding the postoperative complications. The Charlson Comorbidity Index (CCI) is a system of mortality risk assessment. Our purpose is to assess the 90-day postoperative complications after renal transplantation. The secondary objective is to clarify whether CCI predicts complications. We hypothesized increased CCI corresponds to worse complication on the Clavien scale.Methods: This is a retrospective analysis of renal recipients at our institution (2011‒2013) who were ≥18 years old and received complete follow up. CCI, age, gender, body mass index (BMI), and graft type were extracted from the electronic medical records. Complications were scored using the Clavien scale. Descriptive statistics and logistic regression were used to analyze 198 patients.Results: The mean age was 53 (standard deviation [SD] 14), mean BMI 27.4 (SD 14), median CCI 1. Grade 2 or higher (significant) complications occurred in 60% of patients and Grade 3b or higher (severe) in 15% of patients in the 90-day postoperative period. Sixty-eight different complications were identified, the most common being blood transfusion (19%). Logistic regression suggests a predictive value of CCI (odds ratio [OR] 1.70; 95% confidence interval [CI] 1.3‒2.3) for severe complications, with diabetes mellitus and peripheral vascular disease conferring increased risk. Conclusions: Renal transplant carries significant risk. This data can be used to improve patient counselling on the likely postoperative course. Study limitations include the retrospective design, predisposing to potential bias in data capture.

The relationship of age-adjusted Charlson comorbidity ındex and diurnal variation of blood pressure

2018 ◽  
Vol 41 (2) ◽  
pp. 113-117
Author(s):  
Belma Kalaycı ◽  
Yunus Turgay Erten ◽  
Tunahan Akgün ◽  
Turgut Karabag ◽  
Furuzan Kokturk
Keyword(s):  
Blood Pressure ◽  
Diurnal Variation ◽  
Charlson Comorbidity Index ◽  
Comorbidity Index ◽  
Relationship Of ◽  
The Relationship

scholarly journals Charlson Comorbidity Index Is Predictive of Postoperative Clinical Outcome After Single Level Posterior Lumbar Interbody Fusion Surgery: a Single-center Study

2021 ◽  
Author(s):  
Kensuke Shinohara ◽  
Ryo Ugawa ◽  
Shinya Arataki ◽  
Shinnosuke Nakahara ◽  
Kazuhiro Takeuchi
Keyword(s):  
Postoperative Complications ◽  
Clinical Outcome ◽  
Direct Cost ◽  
Charlson Comorbidity Index ◽  
Japanese Orthopaedic Association ◽  
Negative Relationship ◽  
Improvement Rate ◽  
Single Level ◽  
Comorbidity Index ◽  
Group 2

Abstract Background. In several previous studies Charlson comorbidity Index (CCI) score was associated with postoperative complications, mortality and re-admission. There are few reports about the influence of CCI score on postoperative clinical outcome. The purpose of this study was to investigate the influence of comorbidities as calculated with CCI on postoperative clinical outcomes after PLIF.Methods. 366 patients who underwent an elective primary single level PLIF were included. Postoperative clinical outcome was evaluated with the Japanese Orthopaedic Association lumbar score (JOA score). The correlation coefficient between the CCI score and postoperative improvement in JOA score was investigated. Patients were divided into three groups according to their CCI score (0, 1 and 2+). JOA improvement rate, length of stay (LOS) and direct cost were compared between each group. Postoperative complications were also investigated.Results. There was a weak negative relationship between CCI score and JOA improvement rate (r = -0.20). LOS and direct cost had almost no correlation with CCI score. The JOA improvement rate of Group 0 and Group 1 was significantly higher than Group 2+. LOS and direct cost were also significantly different etween Group 0 and Group 2+. There were 14 postoperative complications. Adverse postoperative complications were equivalently distributed in each group, and not associated with the number of comorbidities.Conclusions. A higher CCI score leads to a poor postoperative outcome. The recovery rate of patients with two or more comorbidities was significantly higher than in patients without comorbidities. However, the CCI score did not influence LOS and increased direct costs. The surgeon must take into consideration the patient’s comorbidities when planning a surgical intervention in order to achieve a good clinical outcome.

scholarly journals Elderly Patients with Locally Advanced and Unresectable Non-Small-Cell Lung Cancer May Benefit from Sequential Chemoradiotherapy

Cancers ◽  
2021 ◽  
Vol 13 (18) ◽  
pp. 4534
Author(s):  
Magdalena Zaborowska-Szmit ◽  
Marta Olszyna-Serementa ◽  
Dariusz M. Kowalski ◽  
Sebastian Szmit ◽  
Maciej Krzakowski
Keyword(s):  
Lung Cancer ◽  
Weight Loss ◽  
Elderly Patients ◽  
Charlson Comorbidity Index ◽  
Older Patients ◽  
Locally Advanced ◽  
Small Cell ◽  
Small Cell Lung ◽  
Stage Iiia ◽  
Comorbidity Index

Concurrent chemoradiotherapy is recommended for locally advanced and unresectable non-small-cell lung cancer (NSCLC), but radiotherapy alone may be used in patients that are ineligible for combined-modality therapy due to poor performance status or comorbidities, which may concern elderly patients in particular. The best candidates for sequential chemoradiotherapy remain undefined. The purpose of the study was to determine the importance of a patients’ age during qualification for sequential chemoradiotherapy. The study enrolled 196 patients. Older patients (age > 65years) more often had above the median Charlson Comorbidity Index CCI > 4 (p < 0.01) and Simplified Charlson Comorbidity Index SCCI > 8 (p = 0.03), and less frequently the optimal Karnofsky Performance Score KPS = 100 (p < 0.01). There were no significant differences in histological diagnoses, frequency of stage IIIA/IIIB, weight loss, or severity of smoking between older and younger patients. Older patients experienced complete response more often (p = 0.01) and distant metastases less frequently (p = 0.03). Univariable analysis revealed as significant for overall survival: age > 65years (HR = 0.66; p = 0.02), stage IIIA (HR = 0.68; p = 0.01), weight loss > 10% (HR = 1.61; p = 0.04). Multivariable analysis confirmed age > 65years as a uniquely favorable prognostic factor (HR = 0.54; p < 0.01) independent of lung cancer disease characteristics, KPS = 100, CCI > 4, SCCI > 8. Sequential chemoradiotherapy may be considered as favorable in elderly populations.

scholarly journals Surgery for elderly patients with resectable pancreatic cancer, a comparison with non-surgical treatments: a retrospective study outcomes of resectable pancreatic cancer

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Hyeong Min Park ◽  
Sang-Jae Park ◽  
Sung-Sik Han ◽  
Seoung Hoon Kim
Keyword(s):  
Pancreatic Cancer ◽  
Overall Survival ◽  
Retrospective Study ◽  
Elderly Patients ◽  
Surgical Resection ◽  
Charlson Comorbidity Index ◽  
Resectable Pancreatic Cancer ◽  
Surgery Group ◽  
Comorbidity Index ◽  
High Charlson Comorbidity Index

Abstract Background We designed a retrospective study to compare prognostic outcomes based on whether or not surgical resection was performed in elderly patients aged(≥75 years) with resectable pancreatic cancer. Methods We retrospectively analyzed 49 patients with resectable pancreatic cancer (surgery group, resection was performed for 38 cases; no surgery group, resection was not performed for 11 cases) diagnosed from January 2003 to December 2014 at the National Cancer Center, Korea. Results There was no significant difference in demographics between the two groups. The surgery group showed significantly better overall survival after diagnosis than the no surgery group (2-year survival rate, 40.7% vs. 0%; log-rank test, p = 0.015). Multivariate analysis revealed that not having undergone surgical resection [hazard ratio (HR) 2.412, P = 0.022] and a high Charlson comorbidity index (HR 5.252, P = 0.014) were independent prognostic factors for poor overall survival in elderly patients with early stage pancreatic cancer. Conclusions In the present study, surgical resection resulted in better prognosis than non-surgical resection for elderly patients with resectable pancreatic cancer. Except for patients with a high Charlson comorbidity index, an aggressive surgical approach seems to be beneficial for elderly patients with resectable pancreatic cancer.

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