Oxidative stress-related gene interactions with preterm delivery in Korean women

2008 ◽  
Vol 198 (5) ◽  
pp. 541.e1-541.e7 ◽  
Author(s):  
Young Ju Suh ◽  
Young Ju Kim ◽  
Hyesook Park ◽  
Eun Ae Park ◽  
Eun Hee Ha
Keyword(s):  
Oxidative Stress ◽  
Preterm Delivery ◽  
Gene Interactions ◽  
Korean Women ◽  
Related Gene ◽  
Oxidative Stress Related Gene

scholarly journals Effects of glutamine supplementation on oxidative stress-related gene expression and antioxidant properties in rats with streptozotocin-induced type 2 diabetes

2011 ◽  
Vol 107 (8) ◽  
pp. 1112-1118 ◽  
Author(s):  
Pei-Hsuan Tsai ◽  
Jun-Jen Liu ◽  
Chui-Li Yeh ◽  
Wan-Chun Chiu ◽  
Sung-Ling Yeh
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Amino Acid ◽  
Oxidative Damage ◽  
Antioxidant Capacity ◽  
Enzyme Activities ◽  
Antioxidant Enzyme Activities ◽  
Related Gene ◽  
Gene Expressions ◽  
Oxidative Stress Related Gene

There are close links among hyperglycaemia, oxidative stress and diabetic complications. Glutamine (GLN) is an amino acid with immunomodulatory properties. The present study investigated the effect of dietary GLN on oxidative stress-relative gene expressions and tissue oxidative damage in diabetes. There were one normal control (NC) and two diabetic groups in the present study. Diabetes was induced by an intraperitoneal injection of nicotinamide followed by streptozotocin (STZ). Rats in the NC group were fed a regular chow diet. In the two diabetic groups, one group (diabetes mellitus, DM) was fed a common semi-purified diet while the other group received a diet in which part of the casein was replaced by GLN (DM-GLN). GLN provided 25 % of total amino acid N. The experimental groups were fed the respective diets for 8 weeks, and then the rats were killed for further analysis. The results showed that blood thioredoxin-interacting protein (Txnip) mRNA expression in the diabetic groups was higher than that in the NC group. Compared with the DM group, the DM-GLN group had lower glutamine fructose-6-phosphate transaminase 1, a receptor of advanced glycation end products, and Txnip gene expressions in blood mononuclear cells. The total antioxidant capacity was lower and antioxidant enzyme activities were altered by the diabetic condition. GLN supplementation increased antioxidant capacity and normalised antioxidant enzyme activities. Also, the renal nitrotyrosine level and Txnip mRNA expression were lower when GLN was administered. These results suggest that dietary GLN supplementation decreases oxidative stress-related gene expression, increases the antioxidant potential and may consequently attenuate renal oxidative damage in rats with STZ-induced diabetes.

scholarly journals Novel recombinant human lactoferrin: Differential activation of oxidative stress related gene expression

2013 ◽  
Vol 168 (4) ◽  
pp. 666-675 ◽  
Author(s):  
Marian L. Kruzel ◽  
Jeffrey K. Actor ◽  
Michał Zimecki ◽  
Jasen Wise ◽  
Paulina Płoszaj ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Human Lactoferrin ◽  
Related Gene ◽  
Differential Activation ◽  
Recombinant Human Lactoferrin ◽  
Oxidative Stress Related Gene

A positive correlation between mercury and oxidative stress-related gene expression (GPX3 and GSTM3) is measured in female Double-crested Cormorant blood

Ecotoxicology ◽  
2014 ◽  
Vol 23 (6) ◽  
pp. 1004-1014 ◽  
Author(s):  
Laura A. Gibson ◽  
Raphael A. Lavoie ◽  
Sonja Bissegger ◽  
Linda M. Campbell ◽  
Valerie S. Langlois
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Related Gene ◽  
Positive Correlation ◽  
Oxidative Stress Related Gene ◽  
And Oxidative Stress

scholarly journals N-(2-mercaptopropionyl)-glycine enhances in vitro pig embryo production and reduces oxidative stress

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
J. M. Cambra ◽  
C. A. Martinez ◽  
H. Rodriguez-Martinez ◽  
E. A. Martinez ◽  
C. Cuello ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Culture Medium ◽  
Control Culture ◽  
Related Gene ◽  
In Vitro Production ◽  
Embryo Culture Medium ◽  
Porcine Embryo ◽  
Vitro Production ◽  
Oxidative Stress Related Gene

Abstract This study evaluated the effects of different concentrations (1, 10, 25, 50, and 100 µM) of the antioxidant N-(2-mercaptopropionyl)-glycine (NMPG), during the culture of in vitro-fertilized porcine oocytes. While the highest concentrations of NMPG (50 and 100 µM) were toxic to the developing embryos during the first two days of culture, 25 µM NMPG achieved cleavage rates that were similar to those achieved by the control but did not sustain blastocyst production by Day 7 of culture. Compared to the control culture medium, the culture medium supplemented with 10 µM NMPG increased (P < 0.05) the rates of blastocyst formation, decreased (P < 0.05) the intracellular levels of reactive oxygen substances, and downregulated (P < 0.05) the expression of the oxidative stress related gene GPX1. In conclusion, these results demonstrated that supplementation of porcine embryo culture medium with 10 µM NMPG can attenuate oxidative stress and increase the yield of in vitro production of blastocysts.

73 Genetic variability in oxidative stress-related gene polymorphisms (GSTM1, GSTT1, NOS3 and MTHFR) in preeclampsia and future cardiovascular risk

2016 ◽  
Vol 6 (3) ◽  
pp. 173 ◽  
Author(s):  
Andreia Matos ◽  
Carolina Santos ◽  
Alda Pereira Da Silva ◽  
Maria José Areias ◽  
Irene Rebelo ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Risk ◽  
Genetic Variability ◽  
Gene Polymorphisms ◽  
Related Gene ◽  
Oxidative Stress Related Gene

Identification of the oxidative stress-related gene MSRA as a rheumatoid arthritis susceptibility locus by genome-wide pathway analysis

2010 ◽  
Vol 62 (11) ◽  
pp. 3183-3190 ◽  
Author(s):  
Jose-Ezequiel Martín ◽  
Behrooz Z. Alizadeh ◽  
Miguel A. González-Gay ◽  
Alejandro Balsa ◽  
Dora Pascual-Salcedo ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Oxidative Stress ◽  
Pathway Analysis ◽  
Rheumatoid Arthritis Susceptibility ◽  
Susceptibility Locus ◽  
Related Gene ◽  
Genome Wide ◽  
Oxidative Stress Related Gene ◽  
Arthritis Susceptibility
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