Resting Heart Rate: Risk Indicator and Emerging Risk Factor in Cardiovascular Disease

2015 ◽  
Vol 128 (3) ◽  
pp. 219-228 ◽  
Author(s):  
Michael Böhm ◽  
Jan-Christian Reil ◽  
Prakash Deedwania ◽  
Jae B. Kim ◽  
Jeffrey S. Borer
Keyword(s):  
Cardiovascular Disease ◽  
Heart Rate ◽  
Risk Factor ◽  
Risk Indicator ◽  
Resting Heart Rate ◽  
Rate Risk ◽  
Emerging Risk

Elevated resting heart rate is an independent risk factor for cardiovascular disease in healthy men and women

2010 ◽  
Vol 159 (4) ◽  
pp. 612-619.e3 ◽  
Author(s):  
Marie Therese Cooney ◽  
Erkki Vartiainen ◽  
Tinna Laakitainen ◽  
Anne Juolevi ◽  
Alexandra Dudina ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Heart Rate ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Resting Heart Rate ◽  
Men And Women ◽  
Healthy Men

scholarly journals The impact of resting heart rate measured on cardiovascular events in subject with hypertension

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
P Sobieraj ◽  
J Lewandowski ◽  
M Sinski
Keyword(s):  
Cardiovascular Disease ◽  
Heart Rate ◽  
Risk Factor ◽  
Cardiovascular Events ◽  
Independent Risk Factor ◽  
Hazard Ratio ◽  
Resting Heart Rate ◽  
Coronary Syndrome ◽  
The Impact ◽  
The Relationship

Abstract Background Available evidence does not indicate whether resting heart rate (RHR) is an independent risk factor or just marker of elevated risk. None of the studies assessed impact of RHR on cardiovascular events, when RHR was measured using automated blood pressure measurements (AOBPM). Purpose To assess the relationship between RHR (measured using AOBPM) and cardiovascular events risk in subjects with hypertension. Methods The data of SPRINT trial obtained via NHLBI were used to perform the analysis. SPRINT trial assessed intensive lowering of systolic BP to a target <120 mm Hg in comparison to standard goal (<140 mm Hg). RHR was measured using AOBPM device and calculated as an average of 3 measurements during the baseline visit of the study. Clinical composite endpoint (CE) of the study was defined as: myocardial infarction, acute coronary syndrome, decompensation of heart failure, stroke or cardiovascular death. The relationship between RHR and CE was assessed according to presence of cardiovascular disease (CVD) in past medical history. The statistical methods included t-test and chi-square test, Cox proportional risk models. The Cox models were adjusted for adjusted for age, sex, current smoking status and mean SBP during the trial. Restricted cubic splines were used to describe the relationship between RHR and hazard ratio. Results Data of 1877 participants with CVD and 7484 participants without CVD were analyzed. Subjects with cardiovascular disease were older (69.7±9.5 vs 67.5 years ± 9.4, p<0.001), more often were men (72.8% vs 62.3%, p<0.001) and had prior chronic kidney disease (34.3% vs 26.8%, p<0.001) than subjects without CVD. CE was more than twice often when CVD was present (10.9% vs 4.8%, p<0.001). RHR was lower in subjects with CVD disease than in subjects without CVD (63.6±11 vs 66.9±11.6 bpm, p=0<00.1). Elevated RHR was associated with increased risk both in subjects with and without CVD (Figure 1). The multivariable Cox proportional hazard risk model revealed that RHR>80 bpm is an independent risk factor for CE in subjects without CVD (hazard ratio 1.37, 95% CI 1.01–1.85, p=0.043) while not in subjects with CVD (hazard ratio 0.99, 95% CI 0.57–1.71, p=0.98). Conclusion Elevated RHR (>80 bpm) measured using AOBPM is an independent risk factor for cardiovascular events in subjects with hypertension and without CVD. Figure 1. Heart ratio vs hazard ratio. Funding Acknowledgement Type of funding source: None

scholarly journals Resting Heart Rate and Cardiovascular Disease

2019 ◽  
Vol 12 (3) ◽  
Author(s):  
Susanna C. Larsson ◽  
Nikola Drca ◽  
Amy M. Mason ◽  
Stephen Burgess
Keyword(s):  
Cardiovascular Disease ◽  
Heart Rate ◽  
Resting Heart Rate

Resting heart rate and the use of β-blockers in the treatment of patients with arterial hypertension

2021 ◽  
Vol 14 (1) ◽  
pp. 18-26
Author(s):  
Martyna Waliczek ◽  
Piotr Rozentryt
Keyword(s):  
Heart Rate ◽  
Risk Factor ◽  
Careful Examination ◽  
Resting Heart Rate ◽  
Scientific Societies ◽  
Uncomplicated Hypertension ◽  
Β Blockers ◽  
Standard Risk ◽  
Worse Prognosis ◽  
Elevated Heart Rate

Higher resting heart rate was shown to correlate with worse prognosis both in general population and in various disease groups. Scientific societies dealing with patients with hypertension propose assessment of resting heart rate as a standard risk factor. In patients with uncomplicated hypertension and elevated resting heart rate they propose use of cardioselective β1-adrenolytics. This decision should be preceded by careful examination of potential modified reasons. In the paper we express several concerns regarding standard provision of heart rate lowering drugs in particular clinical situations. The algorithm showing proposed steps in assessment of elevated heart rate is provided.

scholarly journals Preoperative resting heart rate: a novel risk factor for cardiopulmonary complications after lung resection

2019 ◽  
Vol 11 (S3) ◽  
pp. S356-S358
Author(s):  
Xiaoshuang Zhou ◽  
Wanyu Wang ◽  
Lili Huang ◽  
Bin Liu
Keyword(s):  
Heart Rate ◽  
Risk Factor ◽  
Lung Resection ◽  
Resting Heart Rate ◽  
Cardiopulmonary Complications

scholarly journals Optimal Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea Reduces Daytime Resting Heart Rate in Prediabetes: A Randomized Controlled Study

2020 ◽  
Vol 9 (19) ◽  
Author(s):  
Sushmita Pamidi ◽  
Florian Chapotot ◽  
Kristen Wroblewski ◽  
Harry Whitmore ◽  
Tamar Polonsky ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Heart Rate ◽  
Obstructive Sleep Apnea ◽  
Airway Pressure ◽  
Positive Airway Pressure ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Resting Heart Rate ◽  
Randomized Controlled ◽  
Obstructive Sleep

Background It has been widely recognized that obstructive sleep apnea (OSA) is linked to cardiovascular disease. Yet, randomized controlled studies failed to demonstrate a clear cardiovascular benefit from OSA treatment, mainly because of poor adherence to continuous positive airway pressure (CPAP). To date, no prior study has assessed the effect of CPAP treatment on daytime resting heart rate, a strong predictor of adverse cardiovascular outcomes and mortality. Methods and Results We conducted a randomized controlled study in 39 participants with OSA and prediabetes, who received either in‐laboratory all‐night (ie, optimal) CPAP or an oral placebo for 2 weeks. During daytime, participants continued daily activities outside the laboratory. Resting heart rate was continuously assessed over 19 consecutive days and nights using an ambulatory device consisting of a single‐lead ECG and triaxis accelerometer. Compared with placebo, CPAP reduced daytime resting heart rate (treatment difference, −4.1 beats/min; 95% CI, −6.5 to −1.7 beats/min; P =0.002). The magnitude of reduction in daytime resting heart rate after treatment significantly correlated with the magnitude of decrease in plasma norepinephrine, a marker of sympathetic activity ( r =0.44; P =0.02), and the magnitude of decrease in OSA severity (ie, apnea‐hypopnea index [ r =0.48; P =0.005], oxygen desaturation index [ r =0.50; P =0.003], and microarousal index [ r =0.57; P <0.001]). Conclusions This proof‐of‐concept randomized controlled study demonstrates, for the first time, that CPAP treatment, when optimally used at night, reduces resting heart rate during the day, and therefore has positive cardiovascular carry over effects. These findings suggest that better identification and treatment of OSA may have important clinical implications for cardiovascular disease prevention. Registration URL: https:/// www.clini​caltr​ials.gov ; Unique identifier: NCT01156116.

Longitudinal relationships between resting heart rate and biological risk factors for cardiovascular disease: The Amsterdam Growth and Health Study

1998 ◽  
Vol 16 (sup1) ◽  
pp. 17-23 ◽  
Author(s):  
Willem Van Mechelen ◽  
Jos W. R. Twisk ◽  
Frank J. Van Lenthe ◽  
G. Bertheke Post ◽  
Jan Snel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Heart Rate ◽  
Health Study ◽  
Resting Heart Rate ◽  
Biological Risk ◽  
Longitudinal Relationships

scholarly journals Hyperhomocysteinemia: An emerging risk factor for cardiovascular disease

2003 ◽  
Vol 18 (1) ◽  
pp. 8-14 ◽  
Author(s):  
V. Govindaraju ◽  
Neelam ◽  
C. N. Manjunath ◽  
H. Venkataramiah ◽  
T. R. Raghu
Keyword(s):  
Cardiovascular Disease ◽  
Risk Factor ◽  
Emerging Risk

Resting heart rate in relation to blood pressure: Results from the World Health Organization—Cardiovascular Disease and Alimentary Comparison Study

2010 ◽  
Vol 145 (1) ◽  
pp. 73-74 ◽  
Author(s):  
Longjian Liu ◽  
Shunsaku Mizushima ◽  
Katsumi Ikeda ◽  
Yasuo Nara ◽  
Yukio Yamori
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Heart Rate ◽  
World Health Organization ◽  
World Health ◽  
Resting Heart Rate ◽  
Comparison Study ◽  
The World ◽  
Health Organization
Sign in / Sign up

Export Citation Format

Share Document