Dual-emitter Polymer Carbon Dots with Spectral Selection towards Nanomolar Detection of Iron and Aluminum Ions

In this work, blue emission carbon dots (CDs) are synthesized in the one-pot solvothermal method using naringin as precursor. The CDs are used to develop a ratiometric fluorescence sensor for the sensitive analysis of Al3+ with a detection limit of 113.8 nM. A fluorescence emission peak at 500 nm gradually appears, whereas the original fluorescence peak at 420 nm gradually decreases upon the increase in the Al3+ concentration. More importantly, the obvious color change of the CDs probe from blue to green under a 360 nm UV lamp can be identified by a smartphone and combined with the RGB (red/green/blue) analysis. This results in a visual and sensitive analysis of Al3+ with a detection limit of 5.55 μM. Moreover, the high recovery is in the 92.46–104.10% range, which demonstrates the high accuracy of this method for actual samples’ analysis. The use of a smartphone and the RGB analysis greatly simplifies the operation process, saves equipment cost, shortens the detection time, and provides a novel method for the instant, on-site, visual detection of Al3+ in actual samples.

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Effect of octahedrally coordinated aluminum ions on the uptake of Au(III) chloro-hydroxy complexes in Al-Si systems

GEOCHEMICAL JOURNAL ◽

10.2343/geochemj.2.0360 ◽

2015 ◽

Vol 49 (4) ◽

pp. 343-350

Author(s):

Tsubasa Otake ◽

Takushi Yokoyama ◽

Paul C. M. Francisco ◽

Koichiro Watanabe

Keyword(s):

Aluminum Ions

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Heteroatom Doped Carbon Dots with Nanoenzyme Like Properties as Theranostic Platforms for Free Radical Scavenging, Imaging, and Chemotherapy

SSRN Electronic Journal ◽

10.2139/ssrn.3527826 ◽

2020 ◽

Cited By ~ 1

Author(s):

Khalilalrahman Dehvari ◽

Sheng-Hui Chiu ◽

Jin-Sheng Lin ◽

Wubshet Mekonnen Girm ◽

Yong-Chien Ling ◽

...

Keyword(s):

Free Radical ◽

Carbon Dots ◽

Radical Scavenging ◽

Free Radical Scavenging ◽

Doped Carbon Dots

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Carbon Dots for Bacterial Detection and Antibacterial Applications-A Minireview

Current Pharmaceutical Design ◽

10.2174/1381612825666191216150948 ◽

2020 ◽

Vol 25 (46) ◽

pp. 4848-4860 ◽

Cited By ~ 2

Author(s):

Anisha Anand ◽

Gopinathan Manavalan ◽

Ranju Prasad Mandal ◽

Huan-Tsung Chang ◽

Yi-Ru Chiou ◽

...

Keyword(s):

Optical Properties ◽

Carbon Dots ◽

Antibacterial Effect ◽

Bacterial Detection ◽

High Brightness ◽

Photo Catalysis ◽

Wide Range ◽

Prevention And Treatment ◽

Low Toxicity ◽

Conventional Antibiotics

: The prevention and treatment of various infections caused by microbes through antibiotics are becoming less effective due to antimicrobial resistance. Researches are focused on antimicrobial nanomaterials to inhibit bacterial growth and destroy the cells, to replace conventional antibiotics. Recently, carbon dots (C-Dots) become attractive candidates for a wide range of applications, including the detection and treatment of pathogens. In addition to low toxicity, ease of synthesis and functionalization, and high biocompatibility, C-Dots show excellent optical properties such as multi-emission, high brightness, and photostability. C-Dots have shown great potential in various fields, such as biosensing, nanomedicine, photo-catalysis, and bioimaging. This review focuses on the origin and synthesis of various C-Dots with special emphasis on bacterial detection, the antibacterial effect of CDots, and their mechanism.

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Nitrogen and Sulfur Co-doped Fluorescent Carbon Dots for the Detection of Morin and Cell Imaging

Current Analytical Chemistry ◽

10.2174/1573411014666180904104629 ◽

2018 ◽

Vol 15 (1) ◽

pp. 47-55

Author(s):

Xuebing Li ◽

Haifen Yang ◽

Ning Wang ◽

Tijian Sun ◽

Wei Bian ◽

...

Keyword(s):

Microwave Heating ◽

Fluorescent Probe ◽

Fluorescence Intensity ◽

Carbon Dots ◽

Cell Imaging ◽

Water Soluble ◽

Heating Process ◽

X Ray ◽

Doped Carbon Dots ◽

Co Doped

Background: Morin has many pharmacological functions including antioxidant, anticancer, anti-inflammatory, and antibacterial effects. It is commonly used in the treatment of antiviral infection, gastropathy, coronary heart disease and hepatitis B in clinic. However, researches have shown that morin is likely to show prooxidative effects on the cells when the amount of treatment is at high dose, leading to the decrease of intracellular ATP levels and the increase of necrosis process. Therefore, it is necessary to determine the concentration of morin in biologic samples. Method: Novel water-soluble and green nitrogen and sulfur co-doped carbon dots (NSCDs) were prepared by a microwave heating process with citric acid and L-cysteine. The fluorescence spectra were collected at an excitation wavelength of 350 nm when solutions of NSCDs were mixed with various concentrations of morin. Results: The as-prepared NSCDs were characterized by transmission electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The fluorescence intensity of NSCDs decreased significantly with the increase of morin concentration. The fluorescence intensity of NSCDs displayed a linear response to morin in the concentration 0.10-30 μM with a low detection limit of 56 nM. The proposed fluorescent probe was applied to analysis of morin in human body fluids with recoveries of 98.0-102%. Conclusion: NSCDs were prepared by a microwave heating process. The present analytical method is sensitive to morin. The quenching process between NSCDs and morin is attributed to the static quenching. In addition, the cellular toxicity on HeLa cells indicated that the as-prepared NSCDs fluorescent probe does not show obvious cytotoxicity in cell imaging. Our proposed method possibly opens up a rapid and nontoxic way for preparing heteroatom doped carbon dots with a broad application prospect.

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Nitrogen-doped carbon dots from Hutai-8 grape skin and their application in Hg2+ detection

Current Nanoscience ◽

10.2174/1573413716999200819201126 ◽

2020 ◽

Vol 16 ◽

Author(s):

Pan Zhang ◽

Shun-Sheng Zhao ◽

JiaJia Wang ◽

Xiang Rong Liu

Keyword(s):

Heavy Metal ◽

Carbon Source ◽

Fluorescence Quenching ◽

Hydrothermal Method ◽

Water Samples ◽

Carbon Dots ◽

Mercury Ions ◽

Grape Skin ◽

Fluorescent Carbon Dots ◽

Fluorescent Carbon

Background: In recent years, environmental pollution and heavy metal pollution caused by rapid urbanization and industrialization have become increasingly serious. Among them, mercury (II) ion (Hg2+) is one of the highly toxic heavy metal ions, and its pollution comes from various natural resources and human activities. Therefore, people attach great importance to the development of analytical methods for effective analysis and sensitive detection of Hg2+ . Objective: Using grape skin as a green and environmental friendly carbon source, to synthesize fluorescent carbon dots, and try to apply them to the detect the concentration of Hg2+ in water. Method: Using "Hutai No. 8" grape skin as carbon source, fluorescent carbon dots were synthesized by one-step hydrothermal method. Structure and fluorescent properties of the carbon dots were tested using TEM, XPS, XRD and other characterization instruments, and their utilization on detection of mercury ions in the actual water samples was explored. Results: The CDs had a particle size of about 4.8 nm and a spherical shape. There are N-H, C-N, C=O and other functional groups on the surface. It was found that Hg2+ has obvious fluorescence quenching effect on CDs, and thus CDs fluorescence quenching method to detect the concentration Hg2+ was established, and the detection limit is 3.7 μM, which could be applied to test the concentration of Hg2+ in water samples. Conclusion: Using grape skin as carbon source, fluorescent carbon dots were successfully synthesized by hydrothermal method. Carbon dots were used to detect mercury ions in water, and a method for detecting mercury ions in actual water samples was established.

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