Impact of anticholinergic burden on emergency department visits among older adults in Korea: A national population cohort study

2019 ◽  
Vol 85 ◽  
pp. 103912 ◽  
Author(s):  
Sunghee Hwang ◽  
Kwanghee Jun ◽  
Young-Mi Ah ◽  
Euna Han ◽  
Jee Eun Chung ◽  
...  
PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0241824 ◽  
Author(s):  
Frederick K. Ho ◽  
Fanny Petermann-Rocha ◽  
Stuart R. Gray ◽  
Bhautesh D. Jani ◽  
S. Vittal Katikireddi ◽  
...  

Introduction Older people have been reported to be at higher risk of COVID-19 mortality. This study explored the factors mediating this association and whether older age was associated with increased mortality risk in the absence of other risk factors. Methods In UK Biobank, a population cohort study, baseline data were linked to COVID-19 deaths. Poisson regression was used to study the association between current age and COVID-19 mortality. Results Among eligible participants, 438 (0.09%) died of COVID-19. Current age was associated exponentially with COVID-19 mortality. Overall, participants aged ≥75 years were at 13-fold (95% CI 9.13–17.85) mortality risk compared with those <65 years. Low forced expiratory volume in 1 second, high systolic blood pressure, low handgrip strength, and multiple long-term conditions were significant mediators, and collectively explained 39.3% of their excess risk. The associations between these risk factors and COVID-19 mortality were stronger among older participants. Participants aged ≥75 without additional risk factors were at 4-fold risk (95% CI 1.57–9.96, P = 0.004) compared with all participants aged <65 years. Conclusions Higher COVID-19 mortality among older adults was partially explained by other risk factors. ‘Healthy’ older adults were at much lower risk. Nonetheless, older age was an independent risk factor for COVID-19 mortality.


2021 ◽  
Author(s):  
Derek R Manis ◽  
Jeffrey W Poss ◽  
Aaron Jones ◽  
Paula A Rochon ◽  
Susan E Bronskill ◽  
...  

Background: There are no standardized reporting systems or assessments specific to residents of retirement homes in North America. As such, little is known about these older adults as a distinct population. We created a new population-level cohort of residents of retirement homes and examined their health service rates relative to other older adult populations. Methods: We conducted a population-based retrospective cohort study in Ontario, Canada in 2018. The postal codes of all licensed retirement homes (n = 757) were classified and linked to individual-level health system administrative data to derive a cohort of residents of retirement homes. A generalized linear model with a gamma distribution and log link function was used to model rates of emergency department visits, hospitalizations, alternate levels of care (ALC) days, primary care visits, and specialist physician visits. Results: Residents of retirement homes comprised two percent of the older adult population in Ontario (n = 54,773; 2.3%). After adjustment for relevant characteristics, residents of retirement homes had 10 times the rate of emergency department visits (Relative Rate [RR] 10.02, 95% Confidence Interval [CI] 9.83 to 10.21), 20 times the rate of hospitalizations (RR 20.43, 95% CI 20.08 to 20.78), and 44 times the rate ALC days (RR 43.91, 95% CI 43.28 to 44.54) compared to community-dwelling older adults. Interpretation: Residents of retirement homes are a distinct older adult population with high rates of hospital-based care. Our findings contribute to policy debates about the provision of health care in privately operated congregate care settings for older adults.  


2018 ◽  
Vol 31 (10) ◽  
pp. 1099-1109 ◽  
Author(s):  
Adam Arshad ◽  
James Hodson ◽  
Imogen Chappelow ◽  
Nicholas G. Inston ◽  
Andrew R. Ready ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e83224 ◽  
Author(s):  
Danijela Gnjidic ◽  
Sarah N. Hilmer ◽  
Sirpa Hartikainen ◽  
Anna-Maija Tolppanen ◽  
Heidi Taipale ◽  
...  

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