Corrigendum to: “Fasting plasma glucose and subsequent cardiovascular disease among young adults: Analysis of a nationwide epidemiological database” [Atherosclerosis 319 (2021 Feb) 35–41]

Background It is unclear whether reversion from pre–diabetes mellitus to normoglycemia reduces cardiovascular disease (CVD) and all‐cause mortality risk in a Chinese population. We aimed to fill this research gap. Methods and Results The current study included 14 231 Chinese participants (mean age, 58.08 years) who were free from myocardial infarction and stroke at the time of survey participation (2006–2007 and 2008–2009). Participants were divided into 3 categories according to the 2‐year changes in pre–diabetes mellitus, defined by fasting plasma glucose: those with progression to diabetes mellitus, those with reversion from pre–diabetes mellitus to normoglycemia, and those with persistent pre–diabetes mellitus. Cox proportional hazards models were used to calculate hazard ratios (HRs) and their 95% CIs for CVD and all‐cause mortality. After a median follow‐up period of 8.75 years, a total of 879 CVD events (including 180 myocardial infarction events and 713 stroke events) and 941 all‐cause mortality events were recorded. After adjustment for confounding factors, reversion from pre–diabetes mellitus to normoglycemia was associated with decreased risks of CVD (HR, 0.78; 95% CI, 0.64–0.96), myocardial infarction (HR, 0.62; 95% CI, 0.40–0.97), stroke (HR, 0.79; 95% CI, 0.63–0.98), and all‐cause mortality (HR, 0.82; 95% CI, 0.68–0.99) compared with progression to diabetes mellitus. Conclusions Reversion from fasting plasma glucose–defined pre–diabetes mellitus to normoglycemia was associated with a reduction in the future risk of CVD and all‐cause mortality in a Chinese population. Registration URL: https://www.chictr.org ; Unique identifier: ChiCTRTNC‐11001489.

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Visit‐to‐Visit Variability of Fasting Plasma Glucose and the Risk of Cardiovascular Disease and All‐Cause Mortality in the General Population

Journal of the American Heart Association ◽

10.1161/jaha.117.006757 ◽

2017 ◽

Vol 6 (12) ◽

Cited By ~ 16

Author(s):

Anxin Wang ◽

Xiaoxue Liu ◽

Jie Xu ◽

Xiaochen Han ◽

Zhaoping Su ◽

...

Keyword(s):

Cardiovascular Disease ◽

General Population ◽

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Fasting Plasma ◽

All Cause Mortality

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Low Fasting Plasma Glucose Level as a Predictor of Cardiovascular Disease and All-Cause Mortality

Circulation ◽

10.1161/01.cir.101.17.2047 ◽

2000 ◽

Vol 101 (17) ◽

pp. 2047-2052 ◽

Cited By ~ 84

Author(s):

Ming Wei ◽

Larry W. Gibbons ◽

Tedd L. Mitchell ◽

James B. Kampert ◽

Michael P. Stern ◽

...

Keyword(s):

Cardiovascular Disease ◽

Glucose Level ◽

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Plasma Glucose Level ◽

Fasting Plasma Glucose Level ◽

Fasting Plasma ◽

All Cause Mortality

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Normal fasting plasma glucose predicts type 2 diabetes and cardiovascular disease in elderly population in Taiwan

QJM ◽

10.1093/qjmed/hcv204 ◽

2015 ◽

Vol 109 (8) ◽

pp. 515-522 ◽

Cited By ~ 3

Author(s):

C.-L. Huang ◽

H.-W. Chang ◽

J.-B. Chang ◽

J.-H. Chen ◽

J.-D. Lin ◽

...

Keyword(s):

Type 2 Diabetes ◽

Cardiovascular Disease ◽

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Elderly Population ◽

Fasting Plasma

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Correction to: Admission fasting plasma glucose is associated with in-hospital outcomes in patients with acute coronary syndrome and diabetes: findings from the improving Care for Cardiovascular Disease in China - Acute Coronary Syndrome (CCC-ACS) project

BMC Cardiovascular Disorders ◽

10.1186/s12872-021-02118-y ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Nan Ye ◽

Lijiao Yang ◽

Guoqin Wang ◽

Weijing Bian ◽

Fengbo Xu ◽

...

Keyword(s):

Cardiovascular Disease ◽

Acute Coronary Syndrome ◽

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Hospital Outcomes ◽

Coronary Syndrome ◽

Fasting Plasma

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Impact of low fasting plasma glucose on mortality in the general population

Diabetes and Vascular Disease Research ◽

10.1177/1479164120930599 ◽

2020 ◽

Vol 17 (3) ◽

pp. 147916412093059

Author(s):

Parag A Chevli ◽

Muhammad Imtiaz Ahmad ◽

Krupal Hari ◽

Muhammad Ali Anees ◽

Elsayed Z Soliman

Keyword(s):

Cardiovascular Disease ◽

Confidence Interval ◽

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Disease Risk ◽

Cardiovascular Disease Risk ◽

Hazard Ratio ◽

Fasting Plasma ◽

Increased Risk ◽

All Cause Mortality

Background: While the association between hypoglycaemia and poor outcomes in diabetes is well established, it is unclear whether such an association is generalizable to those without diabetes. Methods: A total of 8497 participants free of cardiovascular disease and diabetes from the Third National Health and Nutrition Examination Survey were included. We examined the relationship between baseline low (<80 mg/dL) and high (⩾126 mg/dL) fasting plasma glucose compared to normal levels (80–99 mg/dL). Results: Over a median follow-up of 14 years, 2101 deaths occurred, of which 570 were due to cardiovascular disease. In a model adjusted for sociodemographic and cardiovascular disease risk factors, individuals with low fasting plasma glucose were at increased risk of cardiovascular disease and all-cause mortality [hazard ratio = 1.79 (95% confidence interval = 1.04–3.08) and hazard ratio = 1.35 (95% confidence interval = 1.02–1.78), respectively], compared to those with normal fasting plasma glucose. These associations were stronger among men than women for both cardiovascular disease mortality and all-cause mortality. Conclusion: Low fasting plasma glucose in individuals without diabetes is a risk factor for cardiovascular disease and all-cause mortality, especially in men.

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Fasting Plasma Glucose and Incident Colorectal Cancer: Analysis of a Nationwide Epidemiological Database Fasting Plasma Glucose and Colorectal Cancer

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/clinem/dgab466 ◽

2021 ◽

Author(s):

Hidetaka Itoh ◽

Hidehiro Kaneko ◽

Akira Okada ◽

Yuichiro Yano ◽

Kojiro Morita ◽

...

Keyword(s):

Colorectal Cancer ◽

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Colorectal Polyps ◽

Sensitivity Analyses ◽

Fasting Plasma ◽

Hazard Ratios ◽

Epidemiological Database ◽

History Of

Abstract Context Although diabetes mellitus (DM) was reported to be associated with incident colorectal cancer (CRC), the detailed association between fasting plasma glucose (FPG) and incident CRC has not been fully understood. Objective We assessed whether hyperglycemia is associated with a higher risk for CRC. Design Analyses were conducted using the JMDC Claims Database (n=1,441,311; median age [IQR], 46 [40–54] years; 56.6% men). None of the participants were taking antidiabetic medication or had a history of CRC, colorectal polyps, or inflammatory bowel disease. Participants were categorized as normal FPG, FPG level<100 mg/dL (1,125,647 individuals); normal-high FPG, FPG level=100–109 mg/dL (210,365 individuals); impaired fasting glucose (IFG), FPG level=110–125 mg/dL (74,836 individuals); and DM, FPG level≥126 mg/dL (30,463 individuals). Results Over a mean follow-up of 1,137±824 days, 5,566 CRC events occurred. After multivariable adjustment, the hazard ratios for CRC events were 1.10 (95% CI,1.03–1.18) for normal-high FPG, 1.24 (95% CI, 1.13–1.37) for IFG, and 1.36 (95% CI, 1.19–1.55) for DM vs. normal FPG. We confirmed this association in sensitivity analyses excluding those with a follow-up of< 365 days, and or with obese participants. Conclusion The risk of CRC increased with elevated FPG category. FPG measurements would help identifying people at high-risk for future CRC.

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The association between hypertension and other cardiovascular risk factors among non-diabetic Saudis adults–A cross sectional study

PLoS ONE ◽

10.1371/journal.pone.0246568 ◽

2021 ◽

Vol 16 (2) ◽

pp. e0246568

Author(s):

Ghada M. A. Ajabnoor ◽

Suhad Bahijri ◽

Aliaa Amr Alamoudi ◽

Rajaa Al Raddadi ◽

Jawaher Al-Ahmadi ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Disease ◽

Lipid Profile ◽

Total Cholesterol ◽

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Density Lipoprotein ◽

Lipoprotein Cholesterol ◽

Fasting Plasma

Population specific associations between cardiovascular disease with various risk factors including pre-hypertension and hypertension were reported. We aimed to investigate the association of higher than optimal blood pressure with measures of dysglycemia, dyslipidemia, and markers of inflammation in non-diabetic Saudi adults hoping to improve current Saudi guidelines to prevent cardiovascular disease. Volunteers were recruited randomly from public healthcare centers in Jeddah. Demographic information, blood pressure (BP), and anthropometric measurements were taken. Fasting blood samples were drawn, then again following 1-hour oral glucose tolerance test. Glycated hemoglobin, fasting plasma glucose (FPG), lipid profile, highly sensitive C- reactive protein, gamma glutamyl transferase, and 1-hour plasma glucose were measured. Complete data was found for 742 men and 592 women. Pre-hypertension was found in 47.2% of men, and 24.7% of women, while 15.1% of men, and 14.6% of women were hypertensive. Means of measured variables differed significantly between normotensive, pre-hypertensive, and hypertensive groups of men and women in gender specific manner. Association between measured variables and elevated BP, and hypertension were assessed using logistic regression models. After adjustment for age, body mass index and waist circumference, elevated blood pressure was associated with elevated triglycerides in men, while hypertension was significantly associated with elevated fasting plasma glucose, total cholesterol, triglycerides, low density lipoprotein- cholesterol, and low high density lipoprotein- cholesterol in men, and elevated triglycerides, and total cholesterol in women. Therefore, it is strongly recommended to measure lipid profile, specifically TG, for all diagnosed pre-hypertensive and hypertensive patients in addition to FPG for men.

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