Self-assembled complex of probe peptide – E. Coli RNA I conjugate and nano graphene oxide for apoptosis diagnosis

Biomaterials ◽  
2012 ◽  
Vol 33 (30) ◽  
pp. 7556-7564 ◽  
Author(s):  
Won Ho Kong ◽  
Dong Kyung Sung ◽  
Ki Su Kim ◽  
Ho Sang Jung ◽  
Eun Ji Gho ◽  
...  
Author(s):  
Soumitra Satapathi ◽  
Rutusmita Mishra ◽  
Manisha Chatterjee ◽  
Partha Roy ◽  
Somesh Mohapatra

Nano-materials based drug delivery modalities to specific organs and tissues has become one of the critical endeavors in pharmaceutical research. Recently, two-dimensional graphene has elicited considerable research interest because of its potential application in drug delivery systems. Here we report, the drug delivery applications of PEGylated nano-graphene oxide (nGO-PEG), complexed with a multiphoton active and anti-cancerous diarylheptanoid drug curcumin. Specifically, graphene-derivatives were used as nanovectors for the delivery of the hydrophobic anticancer drug curcumin due to its high surface area and easy surface functionalization. nGO was synthesized by modified Hummer’s method and confirmed by XRD analysis. The formation of nGO, nGO-PEG and nGO-PEG-Curcumin complex were monitored through UV-vis, IR spectroscopy. MTT assay and AO/EB staining found that nGO-PEG-Curcumin complex afforded highly potent cancer cell killing in vitro with a human breast cancer cell line MCF7.


2021 ◽  
Vol 7 (8) ◽  
pp. 2170033
Author(s):  
Gabriel Gaál ◽  
Maria Luisa Braunger ◽  
Varlei Rodrigues ◽  
Antonio Riul ◽  
Henrique Leonel Gomes

2020 ◽  
Vol 1 (8) ◽  
pp. 3000-3008
Author(s):  
Lakshmi Narashimhan Ramana ◽  
Rajeev J. Mudakavi ◽  
Ashok M. Raichur

2D materials such as graphene oxide and molybdenum sulfide exhibit certain properties such as photoluminescence, photothermal and photodynamic effects that have potential in diagnosing and treating cancer.


ACS Nano ◽  
2019 ◽  
Vol 13 (8) ◽  
pp. 9482-9490 ◽  
Author(s):  
Qinwei Wei ◽  
Songfeng Pei ◽  
Guodong Wen ◽  
Kun Huang ◽  
Zhaohong Wu ◽  
...  

2009 ◽  
Vol 95 (10) ◽  
pp. 103104 ◽  
Author(s):  
Yanwu Zhu ◽  
Weiwei Cai ◽  
Richard D. Piner ◽  
Aruna Velamakanni ◽  
Rodney S. Ruoff

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