Clinical Image Quality in Daily Practice of Breast Cancer Mammography Screening

2014 ◽  
Vol 65 (3) ◽  
pp. 199-206 ◽  
Author(s):  
Marie-Hélène Guertin ◽  
Isabelle Théberge ◽  
Michel-Pierre Dufresne ◽  
Hervé Tchala Vignon Zomahoun ◽  
Diane Major ◽  
...  

Objective To assess the quality of screening mammograms performed in daily practice in the Quebec Breast Cancer Screening Program. Subjects and Methods Clinical image quality of a random subsample of 197 screening mammograms performed in 2004-2005 was independently evaluated by 2 radiologists based on the criteria by Canadian Association of Radiologists (CAR). When disagreement occurred for overall judgement or positioning score, the mammograms were reviewed by a third radiologist. Cohen's kappas for interrater agreement were computed. Multivariable robust Poisson regression models were used to study associations of overall quality and positioning with body mass index (BMI) and breast density. Results The CAR criteria were not satisfied for 49.7% of the mammograms. Positioning was the quality attribute most often deficient, with 37.2% of mammograms failing positioning. Interrater agreement ranged from slight (kappa = 0.02 for compression and sharpness) to fair (kappa = 0.30 for exposure). For overall quality, women with a BMI ≥ 30 kg/m2 had a failure proportion of 67.5% compared with 34.9% for women with a BMI<25 kg/m2 (risk ratio 2.1 [95% confidence interval, 1.5-3.0]). For positioning, women with a BMI ≥ 30 kg/m2 had a failure proportion of 53.8% compared with 27.9% for women with a BMI < 25 kg/m2 (risk ratio 1.9 [95% confidence interval, 1.2-3.1]). Effects of breast density on image quality differed among radiologists. Conclusion Despite measures to ensure high-quality imaging, including CAR accreditation, approximately half of this random sample of screening mammograms failed the CAR quality standards. It would be important to define quality targets for screening mammograms carried out in daily practice to interpret such observations.

2018 ◽  
Vol 69 (1) ◽  
pp. 16-23 ◽  
Author(s):  
Isabelle Théberge ◽  
Marie-Hélène Guertin ◽  
Nathalie Vandal ◽  
Jean-Marc Daigle ◽  
Michel-Pierre Dufresne ◽  
...  

Purpose The study sought to examine the association between clinical image quality of mammograms and screening sensitivity. Methods Four radiologists evaluated the clinical image quality of 374 invasive screen-detected cancers and 356 invasive interval breast cancers for which quality evaluation of screening mammograms could be assessed from cancers diagnosed among participants in the Quebec Breast Cancer Screening Program in 2007. Quality evaluation was based on the Canadian Association of Radiologists accreditation criteria, which are similar to those of the American College of Radiology. The association between clinical quality and screening sensitivity was assessed by logistic regression. Adjusted sensitivity and adjusted sensitivity ratios were obtained through marginal standardization. No institutional review board approval was required. Results A proportion of 28% (206 of 730) of screening mammograms had lower overall quality for the majority of assessments. Positioning was the quality attribute that was the most frequently deficient. The 2-year screening sensitivity reached 68%. Sensitivity of screening was not statistically associated with the overall quality (ratio of 2-year sensitivity = 1.03; 95% confidence interval: 0.93-1.15) or with any quality attributes (positioning, exposure, compression, sharpness, artifacts, contrast). Results were similar for the 1-year sensitivity. Conclusions Although not all mammograms in the Quebec screening program met the optimum quality required by the Canadian Association of Radiologists or American College of Radiology accreditation, the screening mammograms produced in this population-based organized screening program reached a high enough level of quality so that the remaining variation in quality is too little to impair screening sensitivity.


2017 ◽  
Vol 59 (6) ◽  
pp. 649-656 ◽  
Author(s):  
Teresa Monserrat ◽  
Elena Prieto ◽  
Benigno Barbés ◽  
Luis Pina ◽  
Arlette Elizalde ◽  
...  

Background In 2014, Siemens developed a new software-based scatter correction (Progressive Reconstruction Intelligently Minimizing Exposure [PRIME]), enabling grid-less digital mammography. Purpose To compare doses and image quality between PRIME (grid-less) and standard (with anti-scatter grid) modes. Material and Methods Contrast-to-noise ratio (CNR) was measured for various polymethylmethacrylate (PMMA) thicknesses and dose values provided by the mammograph were recorded. CDMAM phantom images were acquired for various PMMA thicknesses and inverse Image Quality Figure (IQFinv) was calculated. Values of incident entrance surface air kerma (ESAK) and average glandular dose (AGD) were obtained from the DICOM header for a total of 1088 pairs of clinical cases. Two experienced radiologists compared subjectively the image quality of a total of 149 pairs of clinical cases. Results CNR values were higher and doses were lower in PRIME mode for all thicknesses. IQFinv values in PRIME mode were lower for all thicknesses except for 40 mm of PMMA equivalent, in which IQFinv was slightly greater in PRIME mode. A mean reduction of 10% in ESAK and 12% in AGD in PRIME mode with respect to standard mode was obtained. The clinical image quality in PRIME and standard acquisitions resulted to be similar in most of the cases (84% for the first radiologist and 67% for the second one). Conclusion The use of PRIME software reduces, in average, the dose of radiation to the breast without affecting image quality. This reduction is greater for thinner and denser breasts.


2019 ◽  
Vol 70 (2) ◽  
pp. 186-192 ◽  
Author(s):  
Isabelle Théberge ◽  
Marie-Hélène Guertin ◽  
Nathalie Vandal ◽  
Gary Côté ◽  
Michel-Pierre Dufresne ◽  
...  

Purpose To examine the relation between breast cancer location and screening mammogram sensitivity, and assess whether this association is modified by body mass index (BMI) or breast density. Methods This study is based on all interval cancers (n = 481) and a random sample of screen-detected cancers (n = 481) diagnosed in Quebec Breast Cancer Screening Program participants in 2007. Film-screening mammograms, diagnostic mammograms, and ultrasound reports (when available) were requested for these cases. The breast cancer was then localised in mediolateral oblique (MLO) and craniocaudal (CC) projections of the breast by 1 experienced radiologist. The association between cancer location and screening sensitivity was assessed by logistic regression. Adjusted sensitivity and sensitivity ratios were obtained by marginal standardisation. Results A total of 369 screen-detected and 268 interval cancers could be localised in MLO and/or CC projections. The 2-year sensitivity reached 68%. Overall, sensitivity was not statistically associated with location of the cancer. However, sensitivity seems lower in MLO posterior inferior area for women with BMI ≥ 25 kg/m2 compared to sensitivity in central area for women with lower BMI (adjusted sensitivity ratio: 0.58, 95% confidence interval [CI]: 0.17–0.98). Lower sensitivity was also observed in subareolar areas for women with breast density ≥ 50% compared to the central areas for women with lower breast density (for MLO and CC projections, adjusted sensitivity ratio and 95% CI of, respectively, 0.54 [0.13–0.96] and 0.46 [0.01–0.93]). Conclusions Screening sensitivity seems lower in MLO posterior inferior area in women with higher BMI and in subareolar areas in women with higher breast density. When interpreting screening mammograms, radiologists need to pay special attention to these areas.


2008 ◽  
Vol 4 (4) ◽  
pp. 356-368 ◽  
Author(s):  
CÉdric Marchessoux ◽  
Tom Kimpe ◽  
Tom Bert

2019 ◽  
Vol 92 (1103) ◽  
pp. 20190345 ◽  
Author(s):  
Julia Krammer ◽  
Sergei Zolotarev ◽  
Inge Hillman ◽  
Konstantinos Karalis ◽  
Dzmitry Stsepankou ◽  
...  

Objective: To compare image quality and breast density of two reconstruction methods, the widely-used filtered-back projection (FBP) reconstruction and the iterative heuristic Bayesian inference reconstruction (Bayesian inference reconstruction plus the method of total variation applied, HBI). Methods: Thirty-two clinical DBT data sets with malignant and benign findings, n = 27 and 17, respectively, were reconstructed using FBP and HBI. Three experienced radiologists evaluated the images independently using a 5-point visual grading scale and classified breast density according to the American College of Radiology Breast Imaging-Reporting And Data System Atlas, fifth edition. Image quality metrics included lesion conspicuity, clarity of lesion borders and spicules, noise level, artifacts surrounding the lesion, visibility of parenchyma and breast density. Results: For masses, the image quality of HBI reconstructions was superior to that of FBP in terms of conspicuity,clarity of lesion borders and spicules (p < 0.01). HBI and FBP were not significantly different in calcification conspicuity. Overall, HBI reduced noise and supressed artifacts surrounding the lesions better (p < 0.01). The visibility of fibroglandular parenchyma increased using the HBI method (p < 0.01). On average, five cases per radiologist were downgraded from BI-RADS breast density category C/D to A/B. Conclusion: HBI significantly improves lesion visibility compared to FBP. HBI-visibility of breast parenchyma increased, leading to a lower breast density rating. Applying the HBIR algorithm should improve the diagnostic performance of DBT and decrease the need for additional imaging in patients with dense breasts. Advances in knowledge: Iterative heuristic Bayesian inference (HBI) image reconstruction substantially improves the image quality of breast tomosynthesis leading to a better visibility of breast carcinomas and reduction of the perceived breast density compared to the widely-used filtered-back projection (FPB) reconstruction. Applying HBI should improve the accuracy of breast tomosynthesis and reduce the number of unnecessary breast biopsies. It may also reduce the radiation dose for the patients, which is especially important in the screening context.


2020 ◽  
pp. 20200427
Author(s):  
Gabrielle C Baxter ◽  
Andrew J Patterson ◽  
Ramona Woitek ◽  
Iris Allajbeu ◽  
Martin J Graves ◽  
...  

Objective: To compare diffusion-weighted images (DWI) acquired using single-shot echo-planar imaging (ss-EPI) and multiplexed sensitivity encoding (MUSE) in breast cancer. Methods 20 females with pathologically confirmed breast cancer (age 51 ± 12 years) were imaged with ss-EPI-DWI and MUSE-DWI. ADC, normalised ADC (nADC), blur and distortion metrics and qualitative image quality scores were compared. The Crété-Roffet and Mattes mutual information metrics were used to evaluate blurring and distortion, respectively. In a breast phantom, six permutations of MUSE-DWI with varying parallel acceleration factor and number of shots were compared. Differences in ADC and nADC were compared using the coefficient of variation in the phantom and a paired t-test in patients. Differences in blur, distortion and qualitative metrics were analysed using a Wilcoxon signed-rank test. Results: There was a low coefficient of variation (<2%) in ADC between ss-EPI-DWI and all MUSE-DWI permutations acquired using the phantom. 22 malignant and three benign lesions were identified in 20 patients. ADC values measured using MUSE were significantly lower compared to ss-EPI for malignant but not benign lesions (p < 0.001, p = 0.21). nADC values were not significantly different (p = 0.62, p = 0.28). Blurring and distortion improved with number of shots and acceleration factor, and significantly improved with MUSE in patients (p < 0.001, p = 0.002). Qualitatively, image quality improved using MUSE. Conclusion: MUSE improves the image quality of breast DWI compared to ss-EPI. Advances in knowledge: MUSE-DWI has superior image quality and reduced blurring and distortion compared to ss-EPI-DWI in breast cancer.


2004 ◽  
Vol 77 (915) ◽  
pp. 204-215 ◽  
Author(s):  
A Tingberg ◽  
C Herrmann ◽  
B Lanhede ◽  
A Almén ◽  
M Sandborg ◽  
...  

2016 ◽  
Vol 23 (11) ◽  
pp. 1359-1366 ◽  
Author(s):  
Marie-Hélène Guertin ◽  
Isabelle Théberge ◽  
Hervé Tchala Vignon Zomahoun ◽  
Michel-Pierre Dufresne ◽  
Éric Pelletier ◽  
...  

2015 ◽  
Vol 1 (1) ◽  
pp. 19-22
Author(s):  
Gatot Murti Wibowo ◽  
Dartini Dartini ◽  
Hari Prayitno

Background : Parallel imaging is one of the MRI Scanning techniques used to reduce the overall scan time when the patients with unvoluntary movement being examined with a low magnetic field of 0,35 T.  This research aims to determine the difference between the clinical image quality of the conventional turbo spin echo (TSE) with mSENSE and that of the TSE with GRAPPA parallel imaging techniques from which resulting the MRI T1 and T2 Weighted Images (T1WI and T2WI) sagittal view of lumbar spines, and to define the techniques that clinically provide the most approriate anatomical information.Methods :  This experimental study is made performed by the MRI 0.35 T in which 10 patients who had hernia nucleus pulposus (HNP) desease participated in the experiments ramdomly. The appointed Radiologists blended in the image evaluation using an image checklist to assess the visualisation of anatomical organs on the resulted sagittal lumbar MRI T1WI and T2WI. The two non-parametric statistical tools, Friedman test and the post hoc Wilcoxon matched pairs test, is used to analyze all the data descriptively. Testing the resesearch hypotheses with 95% of confident interval is to proved the differences between resulted sagittal lumbar MRI T1WI and T2WI..Results : The results shown there is a significant difference on the image quality of anatomical information when conventional TSE, parallel imaging-mSENSE and -GRAPPA, with T1WI are applied in the imaging techniques. When those imaging techniques are employed to obtain T2WI, the result is not significant in  contrast.Conclusion : Good imaging techniques with adequate clinical image quality are ranked sequently as the conventional TSE, the  mSENSE and GRAPPA.


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