scholarly journals Withdrawal notice to “Utilizing comparative models in biomedical research” [Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, Volume 255, 2021, 110593, 10.1016/j.cbpb.2021.110593]

2021 ◽  
pp. 110987
Author(s):  
Alexander G. Little ◽  
Matthew E. Pamenter ◽  
Divya Sitaraman ◽  
Nicole M. Templeman ◽  
William G. Willmore ◽  
...  
Keyword(s):  
Molecular Biology ◽  
Biomedical Research ◽  
Comparative Biochemistry

scholarly journals Nanopatterning with Photonic Nanojets: Review and Perspectives in Biomedical Research

Micromachines ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 256
Author(s):  
Salvatore Surdo ◽  
Martí Duocastella ◽  
Alberto Diaspro
Keyword(s):  
Molecular Biology ◽  
High Throughput ◽  
Biomedical Research ◽  
Cost Effective ◽  
Optical Methods ◽  
Nanostructured Surfaces ◽  
Promising Solution ◽  
Potential Impact ◽  
Photonic Nanojets

Nanostructured surfaces and devices offer astounding possibilities for biomedical research, including cellular and molecular biology, diagnostics, and therapeutics. However, the wide implementation of these systems is currently limited by the lack of cost-effective and easy-to-use nanopatterning tools. A promising solution is to use optical methods based on photonic nanojets, namely, needle-like beams featuring a nanometric width. In this review, we survey the physics, engineering strategies, and recent implementations of photonic nanojets for high-throughput generation of arbitrary nanopatterns, along with applications in optics, electronics, mechanics, and biosensing. An outlook of the potential impact of nanopatterning technologies based on photonic nanojets in several relevant biomedical areas is also provided.

scholarly journals Anastacia Awad: Women in STEM outside the lab

2021 ◽  
Vol 218 (4) ◽  
Author(s):  
Stephanie Houston
Keyword(s):  
North Carolina ◽  
Molecular Biology ◽  
Biomedical Research ◽  
Cancer Center ◽  
University Of North Carolina ◽  
Women In Stem ◽  
Diversity And Inclusion ◽  
Chapel Hill ◽  
The University

Anastacia Awad is the Head of Diversity and Inclusion (D&I) globally for the Novartis Institutes for BioMedical Research, which is the research engine of Novartis. She completed her PhD in genetics and molecular biology at the University of North Carolina at Chapel Hill, followed by a postdoc with Alan Hall at Memorial Sloan Kettering Cancer Center. I chatted with Anastacia about her career in science and her journey from the bench to industry.

scholarly journals Implementation of postgenomic technologies for cancer research. Institutional experience

2010 ◽  
Vol 17 (3-4) ◽  
pp. 100-105
Author(s):  
Martina RUDGALVYTĖ ◽  
Diana STANČIŪTĖ ◽  
Kristina BIELSKIENĖ ◽  
Violeta JONUŠIENĖ ◽  
Vida KIRVELIENĖ ◽  
...  
Keyword(s):  
Cancer Research ◽  
Molecular Biology ◽  
Biomedical Research ◽  
New Technologies ◽  
Rapid Development ◽  
Financial Resources ◽  
The Past ◽  
Genomic Technologies ◽  
Institutional Experience

Advance in molecular biology and the new technologies for biomedical research are being rapidly introduced into the research of complex pathologies worldwide. Implementation of these technologies, however, needs substantial financial resources for the equipment and for training the specialists. The rapid development of biomedical research over the past decade increases the risk of moral ageing of the implemented technologies and raises doubts as to whether countries with limited financial resources could afford them. In this article, we share our institutional experience in the implementation of post-genomic technologies in cancer research in Lithuania and stress the need of modern infrastructure in biomedical research, despite the needed efforts and associated risks. Keywords: postgenomic technologies, cancer research

Electron Microscopy in Molecular Biology

1967 ◽  
Vol 25 ◽  
pp. 2-3
Author(s):  
Cecil E. Hall
Keyword(s):  
Electron Microscopy ◽  
Molecular Biology ◽  
Noise Level ◽  
Molecular Structures ◽  
Material Structure ◽  
The Arts ◽  
Shadow Casting ◽  
Electron Image ◽  
High Degree ◽  
Very High

The visualization of organic macromolecules such as proteins, nucleic acids, viruses and virus components has reached its high degree of effectiveness owing to refinements and reliability of instruments and to the invention of methods for enhancing the structure of these materials within the electron image. The latter techniques have been most important because what can be seen depends upon the molecular and atomic character of the object as modified which is rarely evident in the pristine material. Structure may thus be displayed by the arts of positive and negative staining, shadow casting, replication and other techniques. Enhancement of contrast, which delineates bounds of isolated macromolecules has been effected progressively over the years as illustrated in Figs. 1, 2, 3 and 4 by these methods. We now look to the future wondering what other visions are waiting to be seen. The instrument designers will need to exact from the arts of fabrication the performance that theory has prescribed as well as methods for phase and interference contrast with explorations of the potentialities of very high and very low voltages. Chemistry must play an increasingly important part in future progress by providing specific stain molecules of high visibility, substrates of vanishing “noise” level and means for preservation of molecular structures that usually exist in a solvated condition.

Applications of Scanning Microscopy in Biomedical Research

1968 ◽  
Vol 26 ◽  
pp. 354-355
Author(s):  
T. L. Hayes
Keyword(s):  
Information Content ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Three Dimensional ◽  
Dental Enamel ◽  
Resolving Power ◽  
Whole Mount ◽  
Two Parameters ◽  
Content Information ◽  
Sectioned Tissue

Biomedical applications of the scanning electron microscope (SEM) have increased in number quite rapidly over the last several years. Studies have been made of cells, whole mount tissue, sectioned tissue, particles, human chromosomes, microorganisms, dental enamel and skeletal material. Many of the advantages of using this instrument for such investigations come from its ability to produce images that are high in information content. Information about the chemical make-up of the specimen, its electrical properties and its three dimensional architecture all may be represented in such images. Since the biological system is distinctive in its chemistry and often spatially scaled to the resolving power of the SEM, these images are particularly useful in biomedical research.In any form of microscopy there are two parameters that together determine the usefulness of the image. One parameter is the size of the volume being studied or resolving power of the instrument and the other is the amount of information about this volume that is displayed in the image. Both parameters are important in describing the performance of a microscope. The light microscope image, for example, is rich in information content (chemical, spatial, living specimen, etc.) but is very limited in resolving power.

Ultrastructure and analytical microprobe analysis of simian lung mite pigments

1986 ◽  
Vol 44 ◽  
pp. 324-325
Author(s):  
R. W. Cole ◽  
J. C. Kim
Keyword(s):  
Biomedical Research ◽  
Tissue Damage ◽  
Microprobe Analysis ◽  
Old World Monkeys ◽  
Old World ◽  
Experimental Animals ◽  
The Past ◽  
Lung Mite ◽  
Mite Infestations ◽  
Cardiopulmonary System

In recent years, non-human primates have become indispensable as experimental animals in many fields of biomedical research. Pharmaceutical and related industries alone use about 2000,000 primates a year. Respiratory mite infestations in lungs of old world monkeys are of particular concern because the resulting tissue damage can directly effect experimental results, especially in those studies involving the cardiopulmonary system. There has been increasing documentation of primate parasitology in the past twenty years.

An introduction to the themed issue on RNA biology in China

2020 ◽  
Vol 64 (6) ◽  
pp. 863-866
Author(s):  
Zhe Wu
Keyword(s):  
Molecular Biology ◽  
Chinese Society ◽  
Fortieth Anniversary ◽  
Rna Biology ◽  
Research And Education ◽  
Education In China

Abstract The year 2019 marked the fortieth anniversary of the Chinese Society of Biochemistry and Molecular Biology (CSBMB), whose mission is to promote biomolecular research and education in China. The last 40 years have witnessed tremendous growth and achievements in biomolecular research by Chinese scientists and Essays in Biochemistry is delighted to publish this themed issue that focuses on exciting areas within RNA biology, with each review contributed by key experts from China.

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