O-31 Age related characteristics and normative values of F wave in 229 healthy Chinese infants

2019 ◽  
Vol 130 (7) ◽  
pp. e31-e32
Author(s):  
Hua Pan ◽  
Na Chen ◽  
Jinxi Lin ◽  
Fan Jian ◽  
Lei Zhang ◽  
...  
Keyword(s):  
Normative Values ◽  
Age Related ◽  
F Wave ◽  
Healthy Chinese ◽  
O 31

F155. Age related characteristics and normative values of F wave in 229 healthy chinese infants

2018 ◽  
Vol 129 ◽  
pp. e125-e126
Author(s):  
Hua Pan ◽  
Jinxi Lin ◽  
Na Chen ◽  
Fan Jian ◽  
Lei Zhang ◽  
...  
Keyword(s):  
Normative Values ◽  
Age Related ◽  
F Wave ◽  
Healthy Chinese

Age- and gender-related normative value of whole-body sagittal alignment based on 584 asymptomatic Chinese adult population from age 20 to 89

2021 ◽  
Author(s):  
Z Hu ◽  
GCW Man ◽  
KH Yeung ◽  
WH Cheung ◽  
WCW Chu ◽  
...  
Keyword(s):  
Lower Limb ◽  
Sagittal Alignment ◽  
Pearson Correlation ◽  
Age Groups ◽  
Whole Body ◽  
Normative Values ◽  
Chinese Adults ◽  
Age And Gender ◽  
Age Related ◽  
And Gender

To establish the age- and sex-related normative values of sagittal alignment in asymptomatic Chinese adults, and to investigate the changes and possible associated compensation mechanisms across age groups. 584 asymptomatic Chinese adults aged 20–89 years were recruited. Subjects were grouped according to age and gender. Whole-body standing radiographs were acquired for evaluating sagittal alignment from spine to lower limb. Sagittal parameters between gender in different age groups were compared via independent t test. Pearson correlation analysis was used to demonstrate relationships between parameters. Thoracic kyphosis (TK) increased steadily while lumbar lordosis decreased gradually in both genders. Pelvic tilt (PT) in male is greater than in female across all age groups with age related gradual increase. There were significant differences between male and female from 20s to 60s in terms of knee flexion angle (KA) and ankle dorsiflexion angle (AA), but the differences were not significant after 60s. T1 pelvic angle (TPA) was significantly correlated with spinal, pelvic and lower-limb alignment. The older group (≥50 years) had a stronger correlation of TPA with PT and KA, whereas the younger (<50 years) had stronger correlation with TK. This study comprehensively presented the normative sagittal alignment based on a large asymptomatic population, which could serve as an age- and gender-specific reference value for spine surgeons when planning for correction surgery. Age can influence the recruitment of compensation mechanism that involve more pelvic and lower limb mechanisms for elderly people.

scholarly journals Aging Effects on Esophageal Transit Time in the Upright Position During Videofluoroscopy

2020 ◽  
Vol 129 (6) ◽  
pp. 618-624
Author(s):  
Kendrea L. (Focht) Garand ◽  
Lindsey Culp ◽  
Bin Wang ◽  
Kate Davidson ◽  
Bonnie Martin-Harris
Keyword(s):  
Age Groups ◽  
Normative Values ◽  
Barium Swallow ◽  
Aging Effects ◽  
Esophageal Function ◽  
Modified Barium Swallow ◽  
Esophageal Transit ◽  
Esophageal Clearance ◽  
Age Related ◽  
Modified Barium Swallow Study

Objectives: The purpose of this study was to examine age-related effects on esophageal transit times (ETT) among healthy adult participants. Methods: A total of 175 healthy, non-dysphagic participants underwent a modified barium swallow study (MBSS), and ETT was recorded for two standardized swallowing tasks. Differences across age groups were determined using Kruskal–Wallis test. Relationships between an Esophageal Clearance (Modified Barium Swallow Impairment Profile Component 17) score and ETT were also explored. Results: No significant differences were observed in ETT across age groups for nectar-thickened liquid ( P = .335) or pudding ( P = .231) consistencies. No significant differences were observed between males and females in ETT for either the nectar ( P = .112) or pudding trial ( P = .817). For nectar, the mean ETT for patients with Component 17 scores of 2 or greater were significantly higher than that of participants with a score of 0 ( P < .0001). For pudding, participants with a score >0 demonstrated significantly higher mean ETT compared to participants with a score of 0 (with P = .0008 and P < .0001, respectively). Conclusion: Study findings failed to support age-related or sex-related differences in ETT for two standardized swallowing tasks administered during a MBSS in healthy individuals. The normative values following a standardized protocol in this study provide guidance in clinical interpretation of esophageal function.

scholarly journals The Steep Ramp Test in Dutch White Children and Adolescents: Age- and Sex-Related Normative Values

2013 ◽  
Vol 93 (11) ◽  
pp. 1530-1539 ◽  
Author(s):  
Bart C. Bongers ◽  
Sanne I. de Vries ◽  
Joyce Obeid ◽  
Stef van Buuren ◽  
Paul J.M. Helders ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Body Mass ◽  
Exercise Test ◽  
Body Height ◽  
Work Rate ◽  
Additive Models ◽  
Normative Values ◽  
White Children ◽  
Ramp Test ◽  
Age Related

Background The Steep Ramp Test (SRT), a feasible, reliable, and valid exercise test on a cycle ergometer, may be more appealing for use in children in daily clinical practice than the traditional cardiopulmonary exercise test because of its short duration, its resemblance to children's daily activity patterns, and the fact that it does not require respiratory gas analysis. Objective The aim of the present study was to provide sex- and age-related normative values for SRT performance in Dutch white children and adolescents who were healthy and 8 to 19 years old. Design This was a cross-sectional, observational study. Methods A total of 252 Dutch white children and adolescents, 118 boys (mean age=13.4 years, SD=3.0) and 134 girls (mean age=13.4 years, SD=2.9), performed the SRT (work rate increment of 10, 15, or 20 W·10 s−1, depending on body height) to voluntary exhaustion to assess peak work rate (WRpeak). Normative values are presented as reference centiles developed by use of generalized additive models for location, scale, and shape. Results Peak work rate correlated highly with age (r=.915 and r=.811), body mass (r=.870 and r=.850), body height (r=.922 and r=.896), body surface area (r=.906 and r=.885), and fat free mass (r=.930 and r=.902) in boys and girls, respectively. The reference curves demonstrated an almost linear increase in WRpeak with age in boys, even when WRpeak was normalized for body mass. In contrast, absolute WRpeak in girls increased constantly until the age of approximately 13 years, when it started to level off. Peak work rate normalized for body mass in girls showed only a slight increase with age until 14 years of age, when a slight decrease in relative WRpeak was observed. Limitations The sample may not have been entirely representative of the Dutch population. Conclusions The present study provides sex- and age-related normative values for SRT performance in terms of both absolute WRpeak and relative WRpeak, thereby facilitating the interpretation of SRT results by clinicians and researchers.

scholarly journals Functional analysis and evaluation of respiratory cilia in healthy Chinese children

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
So-Lun Lee ◽  
Christopher O’Callaghan ◽  
Yu-Lung Lau ◽  
Chun-Wai Davy Lee
Keyword(s):  
High Speed ◽  
Beat Frequency ◽  
Ciliary Beat Frequency ◽  
Chinese Children ◽  
Second Hand Smoke ◽  
Reference Ranges ◽  
Age Related ◽  
Beat Pattern ◽  
European Values ◽  
Healthy Chinese

Abstract Background To aid in the diagnosis of Primary Ciliary Dyskinesia (PCD) and to evaluate the respiratory epithelium in respiratory disease, normal age-related reference ranges are needed for ciliary beat frequency (CBF), beat pattern and ultrastructure. Our aim was to establish reference ranges for healthy Chinese children. Methods Ciliated epithelial samples were obtained from 135 healthy Chinese children aged below 18 years by brushing the inferior nasal turbinate. CBF and beat pattern were analysed from high speed video recordings. Epithelial integrity and ciliary ultrastructure were assessed using transmission electronic microscopy. Results The mean CBF from 135 children studied was 10.1 Hz (95% CI 9.8 to 10.4). Approximately 20% (ranged 18.0–24.2%) of ciliated epithelial edges were found to have areas of dyskinetically beating cilia. Normal beat pattern was observed in ciliated epithelium from all subjects. We did not find any effect of exposure to second hand smoke on CBF in our subjects. Microtubular defects were found in 9.3% of all of the cilia counted in these children, while other ciliary ultrastructural defects were found in less than 3%. Conclusions We established the reference range for CBF, beat pattern and ultrastructure in healthy Chinese children. Using similar methodology, we found a lower overall mean CBF than previously obtained European values. This study highlights the need to establish normative data for ciliary function in different populations.

scholarly journals Age-Related Decline in Associative Learning in Healthy Chinese Adults

PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e80648 ◽  
Author(s):  
Annie Lee ◽  
Jo Archer ◽  
Caroline Kai Yun Wong ◽  
Shen-Hsing Annabel Chen ◽  
Anqi Qiu
Keyword(s):  
Associative Learning ◽  
Chinese Adults ◽  
Age Related ◽  
Healthy Chinese

scholarly journals Hippocampal volume across age: Nomograms derived from over 19,700 people in UK Biobank

2019 ◽  
Author(s):  
Lisa Nobis ◽  
Sanjay G. Manohar ◽  
Stephen M. Smith ◽  
Fidel Alfaro-Almagro ◽  
Mark Jenkinson ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Large Scale ◽  
Objective Evaluation ◽  
Hippocampal Volume ◽  
Volume Status ◽  
Normative Values ◽  
Grey Matter Volume ◽  
Uk Biobank ◽  
Age Related ◽  
The Uk

AbstractMeasurement of hippocampal volume has proven useful to diagnose and track progression in several brain disorders, most notably in Alzheimer’s disease (AD). For example, an objective evaluation of a patient’s hippocampal volume status may provide important information that can assist diagnosis or risk stratification of AD. However, clinicians and researchers require access to age-related normative percentiles to reliably categorise a patient’s hippocampal volume as being pathologically small. Here we analysed effects of age, sex, and hemisphere on the hippocampus and neighbouring temporal lobe volumes, in 19,793 generally healthy participants in the UK Biobank. A key finding of the current study is a significant acceleration in the rate of hippocampal volume loss in middle age, more pronounced in females than in males. In this report, we provide normative values for hippocampal and total grey matter volume as a function of age for reference in clinical and research settings. These normative values may be used in combination with our online, automated percentile estimation tool to provide a rapid, objective evaluation of an individual’s hippocampal volume status. The data provide a large-scale normative database to facilitate easy age-adjusted determination of where an individual hippocampal and temporal lobe volume lies within the normal distribution.

scholarly journals Reference Ranges for Respiratory Ciliary Function for Chinese Children May Not Be Extrapolated From European Data

2020 ◽  
Author(s):  
So-Lun LEE ◽  
Christopher O'Callaghan ◽  
Yu-Lung Lau ◽  
Chun-Wai Davy Lee
Keyword(s):  
High Speed ◽  
Beat Frequency ◽  
Ciliary Beat Frequency ◽  
Chinese Children ◽  
Second Hand Smoke ◽  
Reference Ranges ◽  
Ciliary Function ◽  
Age Related ◽  
Beat Pattern ◽  
Healthy Chinese

Abstract Background:To aid in the diagnosis of Primary Ciliary Dyskinesia (PCD) and to evaluate the respiratory epithelium in respiratory disease, normal age related reference ranges are needed for ciliary beat frequency (CBF), beat pattern and ultrastructure. These reference data are not available for Asian or Chinese children. Our aim was to establish reference ranges for healthy Chinese children.Methods:Ciliated epithelial samples were obtained from 135 health Chinese children aged below 18 years by brushing the inferior nasal turbinate. CBF and beat pattern were analysedfrom high speed video recordings. Epithelial integrity and ciliary ultrastructure were assessed using transmission electronic microscopy. Results:The mean CBF from 135 children studied was 10.1 Hz (95% CI 9.8 to 10.4). Approximately 20% (ranged 18.0-24.2 %) of ciliated epithelial edges were found to have areas of dyskinetically beating cilia. Normal beat pattern was observed in ciliated epithelium from all subjects. We did not find any effect of exposure to second hand smoke on CBF in our subjects. Microtubular defects were found in 9.3% of all of the cilia counted in these children while other ciliary ultrastructural defects were found in less than 3%.Conclusions: We established the reference range for CBF, beat pattern and ultrastructure in healthy Chinese children. Using similar methodology, we found a lower overall mean CBF than previously obtained European values. This study highlights the need to establish normative data for ciliary function in different populations.

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