“Adherence to nutritional support: effects on quality of life and nutritional parameters”: anyvida trial

2021 ◽  
Vol 46 ◽  
pp. S719
Author(s):  
C. García-García ◽  
R. Rioja Vázquez ◽  
I. Vegas Aguilar ◽  
I. Cornejo-Pareja ◽  
F.J. Tinahones Madueño ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nutritional Support ◽  
Support Effects ◽  
Nutritional Parameters

scholarly journals The Effects of Oral Nutritional Support on the Ability of the COVID-19 Patients to Recover: A Prospective, Open, Multicenter, Comparative in Two Groups, Observational Study

2021 ◽  
Vol 1 (4) ◽  
pp. 165-177
Author(s):  
Sergey V. Sviridov ◽  
Kirill Y. Krylov ◽  
Irina V. Vedenina ◽  
Rubenas Mohan
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Length Of Stay ◽  
Observational Study ◽  
Nutritional Support ◽  
Respiratory Support ◽  
Control Group ◽  
Study Group ◽  
Sf 36

Background. Nutritional insufficiency and decreased muscle mass of patients diagnosed with COVID-19 leads to prolonged respiratory support, stay in ICU and hospital, as well as reduced muscle strength and quality of life in the recovery period after a viral pneumonia caused by COVID-19. Aims: To study the effects of oral nutritional support on the physical health recovery of COVID-19 patients. Materials and methods. A prospective, open, multicenter, comparative observative study of two groups, observational study was initiated to evaluate the effects of oral nutritional support (ONS) by Nutridrink 200 ml on the ability of COVID-19 patients to recover. The patients with these criteria were included in the study: aged 1869; a confirmed COVID-19 infection; requires respiratory support; ability to consume more than 60% of food from the total required; presence of a signed consent form. One group received supplementary oral nutritional support (ONS) everyday for 28 days from the day of inclusion. The other group received standard diet. The primary endpoint was the evaluation of quality of life using the SF-36 questionnaire and the changes in the hand grip strength between the 3rd and 1st visits. Secondary endpoints of the study were length of stay in hospital and duration of respiratory support in the hospital. Results. 205 patients with a COVID-19 infection were included in the study. The final number of patients included in the study was 185 patients. Median age was 55 years old. The majority of patients were male 57.84% (107 patients). Upon evaluation of the physical component of quality of life using the SF-36 questionnaire, we obtained a statistically significant difference between the control and study groups on the 4th visit 44.285.45 and 46.586.76 respectively (p=0.012). Muscle strength was statistically different in the control (4.011.15 daN) and study (6.12.06 daN) groups (p 0.0001). The duration of respiratory support was significantly lower in the study group, 6.71.30 days as opposed to 8.141.52 days in the control group (p 0.0001). Also, in the group with oral nutritional support, there was a statistically significant decrease in the length of stay in hospital. In the control group, the average length of stay in hospital was 16.472.93 days, whereas in the study group it was 13.162.69 days (p 0.0001). Conclusion. Oral nutritional support given to oxygen dependent COVID-19 patients improves rehabilitation potential including preservation of muscle mass and function, reducing oxygen support requirements and length of stay in hospital.

scholarly journals Nutritional Risk Screening and Assessment

2019 ◽  
Vol 8 (7) ◽  
pp. 1065 ◽  
Author(s):  
Emilie Reber ◽  
Filomena Gomes ◽  
Maria F. Vasiloglou ◽  
Philipp Schuetz ◽  
Zeno Stanga
Keyword(s):  
Quality Of Life ◽  
At Risk ◽  
Nutritional Support ◽  
Nutritional Risk ◽  
Nutritional Management ◽  
Risk Screening ◽  
Care Plans ◽  
Patients At Risk ◽  
Nutritional Risk Screening

Malnutrition is an independent risk factor that negatively influences patients’ clinical outcomes, quality of life, body function, and autonomy. Early identification of patients at risk of malnutrition or who are malnourished is crucial in order to start a timely and adequate nutritional support. Nutritional risk screening, a simple and rapid first-line tool to detect patients at risk of malnutrition, should be performed systematically in patients at hospital admission. Patients with nutritional risk should subsequently undergo a more detailed nutritional assessment to identify and quantify specific nutritional problems. Such an assessment includes subjective and objective parameters such as medical history, current and past dietary intake (including energy and protein balance), physical examination and anthropometric measurements, functional and mental assessment, quality of life, medications, and laboratory values. Nutritional care plans should be developed in a multidisciplinary approach, and implemented to maintain and improve patients’ nutritional condition. Standardized nutritional management including systematic risk screening and assessment may also contribute to reduced healthcare costs. Adequate and timely implementation of nutritional support has been linked with favorable outcomes such as a decrease in length of hospital stay, reduced mortality, and reductions in the rate of severe complications, as well as improvements in quality of life and functional status. The aim of this review article is to provide a comprehensive overview of nutritional screening and assessment methods that can contribute to an effective and well-structured nutritional management (process cascade) of hospitalized patients.

scholarly journals Impact of a Tailored Nutritional and Physical Exercise Programme on Efficacy and Functional Outcomes in Older Patients with Hematological Malignancies Classified By Frailty Profile

Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 3424-3424
Author(s):  
Maite Antonio ◽  
Montserrat Arnan Sangerman ◽  
Eva Domingo-Domenech ◽  
Eva González-Barca ◽  
Casimiro Javierre ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Exercise ◽  
Older Patients ◽  
Nutritional Support ◽  
Hematological Malignancies ◽  
Moderate Intensity ◽  
Control Group ◽  
Chi Square ◽  
Before And After

BACKGROUND As the result of population aging, hematologists increasingly face the challenge of effectively managing older adults with oncological diseases. The heterogeneity of the aging process means that chronological age does not serve as a pivotal variable on which the clinical or treatment decisions are based. To improve outcomes in older population it is critical to select treatment considering patients' frailty profile and patients' needs to ensure they complete the treatment proposedComprehensive geriatric assessment (CGA) is a gold-standard multidimensional tool to characterize older patients according to their biological frailty profile. CGA identifies patient- and condition-related factors that might be potentially reversible through subsequent clinical interventions Older patient may present some degree of physical decline during the treatment due to variables related to the disease itself and/or to the treatment. This can lead to an accelerated decline from aging, affect their functional independence, their quality of life, and their ability to complete the treatment There is evidence that nutritional support and physical exercise during and after oncological treatments provides benefits in muscular and aerobic condition, quality of life, fatigue and adherence to treatment. But data on hematological patient, usually treated with more intensive schemes associated with a higher incidence of cytopenia and fatigue is scarce ENDPOINT - PRIMARY To determine the impact of an individualized geriatric intervention program of physical exercise and nutritional support on adherence to planned oncological treatment in patients ≥ 70 years with hematological malignancies - SECONDARY Analyze the relation between CGA and aging biomarkersEvaluate adherence to the intervention programDetermine the rate of completion and causes for non-completion of treatmentMeasure at the beginning and end of intervention, and 6 months after treatment completion: The program's effect on physical condition parametersChanges in functional capacity: basic and instrumental activities of daily lifeLevels of fatigueQuality of lifeDetermine the incidence and degree of severity of toxicityDetermine treatment response parameters: time to treatment failure and to progression, disease-free, overall and cancer-specific survival METHODS DESIGN Prospective clinical trial, randomized, parallel and open groupsSETTING Comprehensive cancer centerINCLUSION CRITERIA Histopathological diagnosis of hematological malignancies: multiple myeloma, lymphoproliferative syndromes and myelodisplastic syndromesPatients who meet criteria for medical treatment: chemotherapy, radiotherapy, immunotherapy or targeted therapiesPatients in optimal conditions to perform moderate intensity physical exercise (responsible doctor's judgement)Signature of informed consentEXCLUSION CRITERIA Failure to meet any of the inclusion criteria.INTERVENTION All patients will be assessed through a CGA. The intervention group will received the standard treatment according to the clinical protocol of the institution and will participate in a program of personalized physical exercise and nutritional support. The control group will be treated in a standard manner according to the institution's clinical protocolRANDOMIZATION Subjects will be assigned a 1.1 ratio to one of the groups using a simple randomisation methodMAIN VARIABLE: rate of treatment compliance (relationship between the prescribed dose and the dose administered)SECONDARY VARIABLES: CGA scales, aging biomarkers, nutritional parameters and basal body composition before and after the intervention, quality of life before and after the intervention, toxicity and complications during treatment and response to treatment.STATISTICAL ANALYSIS The comparability of the components of the intervention and control group will be analyzed by Chi square test (qualitative variables) and Student's t test and Wilcoxson test (quantitative variables). The analysis of the intervention will be carried out according to the intention of treatment. The main variable will be analyzed by comparison test of chi-square proportions and confidence intervals will be calculated. The variable will be measured at the end of the intervention, according to the degree of compliance with the nutritional and physical exercise program. Disclosures Domingo-Domenech: Takeda: Consultancy, Membership on an entity's Board of Directors or advisory committees, Other: Travel expenses; Seattle Genetics: Research Funding; Bristol-Myers Squibb: Other: Travel expenses; Roche: Other: Travel expenses. González-Barca:Kiowa: Consultancy; Roche: Consultancy, Honoraria; Celgene: Consultancy; Celtrion: Consultancy; AbbVie: Consultancy, Honoraria; Janssen: Consultancy, Honoraria; Takeda: Honoraria. Sureda:Roche: Honoraria; BMS: Consultancy, Honoraria; Novartis: Consultancy, Honoraria; Janssen: Consultancy, Honoraria; Gilead: Consultancy; Sanofi: Consultancy, Honoraria; Takeda: Consultancy, Honoraria, Speakers Bureau.

Long-term outcomes in patients with encapsulating peritoneal sclerosis managed with nutritional support

2020 ◽  
Vol 40 (5) ◽  
pp. 487-495
Author(s):  
Arunraj Navaratnarajah ◽  
Nevine El-Sherbini ◽  
Edwina A Brown
Keyword(s):  
Quality Of Life ◽  
Nutritional Support ◽  
Nutritional Assessment ◽  
Long Term Outcomes ◽  
Term Survival ◽  
Radiological Score ◽  
Serial Ct ◽  
End Stage

Background: Little is known about long-term survivors with encapsulating peritoneal sclerosis (EPS). Published literature focuses on patients managed surgically. We describe our experience of the long-term outcomes in patients with EPS conservatively managed with nutritional support alone. Methods: This is a single-centre retrospective observational study of patients who had survived for ≥5 years since diagnosis. EPS survivors were invited for review of symptoms, nutritional assessment and evaluation of quality of life. Radiological progression was assessed based on serial computed tomography (CT) scores for each patient. Results: A total of 23 patients with a diagnosis of EPS for at least 5 years were identified, with 18 patients alive at the time of the study. Of these 18 patients, 10 patients transferred to haemodialysis (HD) and 8 patients received kidney transplants. Commonest symptoms were nausea (91%) and vomiting (73%). Mean body mass index for patients was within the ideal and healthy range, with only 11% suffering from continued weight loss. In all, 70% EPS survivors on HD received nutritional support compared to 15% of those with transplants; 17% required ongoing parenteral nutrition. Of the 11 patients with serial CT scans at least 4 years apart, 10 had an increase in radiological score for EPS but with no apparent correlation to clinical outcomes. There were no significant differences in the reported quality of life between EPS survivors on HD and those transplanted, with self-rated health status equivalent to that reported for the general end-stage kidney disease (ESKD) population. Conclusion: Long-term survival following EPS managed conservatively with nutritional support is feasible, with the majority no longer requiring nutritional support and having a quality of life similar to other patients with ESKD.

PP148-MON MALNUTRITION, QUALITY OF LIFE AND CANCER: ASSOCIATION BETWEEN DIFFERENT NUTRITIONAL PARAMETERS

2011 ◽  
Vol 6 (1) ◽  
pp. 170
Author(s):  
S.P. Orlandi ◽  
M.C.F. Assunçâo ◽  
C.A. Pastore ◽  
M.C. Gonzalez
Keyword(s):  
Quality Of Life ◽  
Nutritional Parameters

Perception of Quality of Life of Persons with HIV/AIDS and Maintenance of Nutritional Parameters While on Protease Inhibitors

1999 ◽  
Vol 13 (7) ◽  
pp. 427-433 ◽  
Author(s):  
PAMELA S. ECHEVERRIA ◽  
SATYA S. JONNALAGADDA ◽  
BARBARA L. HOPKINS ◽  
CHRISTINE A. ROSENBLOOM
Keyword(s):  
Quality Of Life ◽  
Protease Inhibitors ◽  
Nutritional Parameters ◽  
Perception Of Quality ◽  
Hiv Aids

scholarly journals Prospects for the use of additional oral nutrition (siping) in nutritional support of cancer patients

2020 ◽  
Vol 7 (3) ◽  
pp. 136-145
Author(s):  
E. V. Gameeva
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Nutritional Support ◽  
Clinical Symptoms ◽  
Early Stage ◽  
Nutritional Therapy ◽  
Oral Nutrition ◽  
Analytical Review ◽  
Anticancer Treatment

Most of cancer patients are faced with various nutritional disorders at the process of anticancer treatment. Cancer-induced metabolic abnormalities are impeded muscle recovery even with normal nutritional support. As a result, malnutrition can develop into the cancer anorexia-cachexia syndrome, aggravate the disease and adversely affect the outcome of treatment. Purpose of the study. Evaluate the effectiveness of oral nutritional support in cancer patients at different stages of antitumor treatment. Materials and methods. The literature research was conducted with keywords «quality of life», «nutritional support», «oral nutrition», «cancer» in such databases as eLIBRARY and MEDLINE in Russian and English. There was performed an analytical review of various methods of quality of life assessing, methods for assessing nutritional status and measures of choice for the necessary nutritional therapy in cancer patients. Results. Nutritional support at all stages of treatment for cancer patients may have an impact on treatment outcomes and the incidence of complications. In case of palliative care, nutritional support can be aimed at improving patient's quality of life and reducing the severity of a number of clinical symptoms, in particular, such as nausea and vomiting. Conclusion. It has been shown, that individual and intensive elimination of nutritional defects improves the quality of life of patients, especially if this occurs at an early stage of the disease. Further study of the effect from nutrition-oriented interventions in cancer patients undergoing treatment, is needed.

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