Human metapneumovirus in Jordan: prevalence and clinical symptoms in hospitalized pediatric patients and molecular virus characterization

2012 ◽  
Vol 74 (3) ◽  
pp. 288-291 ◽  
Author(s):  
Lina M. Qaisy ◽  
Mamdoh M. Meqdam ◽  
Asem Alkhateeb ◽  
Abdallah Al-Shorman ◽  
Hiyam O. AL-Rousan ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Clinical Symptoms ◽  
Human Metapneumovirus

scholarly journals Allergic rhinitis in pediatric practice: how to identify and manage

2018 ◽  
pp. 142-146
Author(s):  
N. V. Minaeva ◽  
I. P. Koryukina
Keyword(s):  
Health Care ◽  
Allergic Rhinitis ◽  
Child Health ◽  
Pediatric Patients ◽  
Clinical Symptoms ◽  
Quality Criteria ◽  
Care Quality ◽  
Symptomatic Therapy ◽  
Child Health Care ◽  
Pediatric Practice

The issues of diagnosis and management of allergic rhinitis (AR) in pediatric patients are considered on the basis of the current Russian clinical guidelines. The article presents the paediatrician tasks on the collection of anamnesis, the assessment of clinical symptoms, the setting of a preliminary diagnosis, the development of a diagnosis and therapy plan taking into account the modern medical care quality criteria. It also discloses the general principles of AR treatment, approaches to emergency symptomatic therapy using a combined intranasal drug Vibrocil (dimethindene + phenylephrine). The paper provides recommendations for the management of patients with allergic rhinitis in the district covered by child health care.

Adenoids and clinical symptoms: Epidemiology of a cohort of 795 pediatric patients

2015 ◽  
Vol 79 (12) ◽  
pp. 2137-2141 ◽  
Author(s):  
Fabio Pagella ◽  
Mara De Amici ◽  
Alessandro Pusateri ◽  
Guido Tinelli ◽  
Elina Matti ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Clinical Symptoms

scholarly journals Analysis of the risk of ovarian torsion in 49 consecutive pediatric patients treated at a single institution

2019 ◽  
Vol 2 (2) ◽  
pp. e000009
Author(s):  
Koshiro Sugita ◽  
Takafumi Kawano ◽  
Mukai Motoi ◽  
Toshihiro Muraji ◽  
Shun Onishi ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Pediatric Patients ◽  
Clinical Symptoms ◽  
White Cell Count ◽  
Ovarian Torsion ◽  
Imaging Findings ◽  
Single Institution ◽  
Exact Test ◽  
Cystic Masses ◽  
Ovarian Masses

PurposeAn early diagnosis of ovarian torsion is sometimes difficult due to variable clinical symptoms and non-specific imaging findings. We retrospectively reviewed patients with pediatric ovarian masses manifesting torsion.MethodsFifty-eight ovarian masses (55 episodes) in 49 non-neonatal patients treated from April 1984 to March 2017 were retrospectively analyzed. The Mann-Whitney U test and Fisher’s exact test were used for the statistical analysis.ResultsThe median age of these 55 episodes was 10.5 years old (range 1.0–23.0). Thirty-three patients presented with abdominal pain. Forty-five tumors and 13 cystic masses were resected and diagnosed pathologically (50 benign and 8 malignant). Torsion was identified in 15 cases (25.9%) at operation. The torsion masses were all benign, and 8 ovaries (53.3%) were successfully preserved. Comparing the torsion cases with the non-torsion cases, only the white cell count was significantly higher in the torsion cases (p=0.0133) and in the patients presented with abdominal pain (p=0.0068). The duration of abdominal pain was significantly shorter in ovary preserved cases than in oophorectomy cases.ConclusionThe white blood cell may be a helpful indicator of the presence of torsion as well as the need for surgery.

scholarly journals The Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2 in a Pediatric Healthcare Network in the United States

2020 ◽  
Vol 9 (5) ◽  
pp. 523-529 ◽  
Author(s):  
William R Otto ◽  
Sarah Geoghegan ◽  
Leila C Posch ◽  
Louis M Bell ◽  
Susan E Coffin ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Pediatric Patients ◽  
Clinical Symptoms ◽  
Healthcare Providers ◽  
Case Series ◽  
The United States ◽  
Retrospective Case ◽  
White Children ◽  
Healthcare Network ◽  
Pediatric Healthcare

Abstract Background Understanding the prevalence and clinical presentation of coronavirus disease 2019 in pediatric patients can help healthcare providers and systems prepare and respond to this emerging pandemic. Methods This was a retrospective case series of patients tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across a pediatric healthcare network, including clinical features and outcomes of those with positive test results. Results Of 7256 unique children tested for SARS-CoV-2, 424 (5.8%) tested positive. Patients aged 18–21 years had the highest test positive rate (11.2%), while those aged 1–5 years had the lowest (3.9%). By race, 10.6% (226/2132) of black children tested positive vs 3.3% (117/3592) of white children. By indication for testing, 21.1% (371/1756) of patients with reported exposures or clinical symptoms tested positive vs 3.8% (53/1410) of those undergoing preprocedural or preadmission testing. Of 424 patients who tested positive for SARS-CoV-2, 182 (42.9%) had no comorbidities, 87 (20.5%) had asthma, and 55 (13.0%) were obese. Overall, 52.1% had cough, 51.2% fever, and 14.6% shortness of breath. Seventy-seven (18.2%) SARS-CoV-2–positive patients were hospitalized, of whom 24 (31.2%) required respiratory support. SARS-CoV-2-targeted antiviral therapy was given to 9 patients, and immunomodulatory therapy to 18 patients. Twelve (2.8%) SARS-CoV-2-positive patients required mechanical ventilation, and 2 patients required extracorporeal membrane oxygenation. Two patients died. Conclusions In this large cohort of pediatric patients tested for SARS-CoV-2, the rate of infection was low but varied by testing indication. The majority of cases were mild and few children had critical illness.

scholarly journals Patient-perceived Burden of Disease in Pediatric Relapsing Polychondritis

2019 ◽  
Vol 46 (12) ◽  
pp. 1627-1633
Author(s):  
Casey A. Rimland ◽  
Marcela A. Ferrada ◽  
Ninet Sinaii ◽  
Keith A. Sikora ◽  
Robert A. Colbert ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Pediatric Patients ◽  
Clinical Symptoms ◽  
Diagnostic Delay ◽  
Relapsing Polychondritis ◽  
Adult Patients ◽  
Multisystem Disease ◽  
Patient Reported ◽  
Airway Symptoms ◽  
Similar Survey

Objective.To assess patient-reported burden of disease in pediatric patients with relapsing polychondritis (RP) and to compare those findings to adult patients.Methods.A survey based on known clinical symptoms of RP was developed and administered to patients with a pediatric diagnosis of RP. Adult patients completed a similar survey.Results.Twenty-one pediatric patients, or their parents, completed surveys. Median age at symptom onset was 6 years (interquartile range 1.8–12). Prior to diagnosis, most pediatric patients went to the emergency room (ER; 61.9%), saw > 3 physicians (57.1%), and took > 1 year to be diagnosed (61.9%). Pediatric patients were often diagnosed with asthma (42.9%), ear infections (42.9%), or sinusitis (33.3%) prior to diagnosis of RP. Symptoms prior to diagnosis included ear pain/redness (85.7%), joint pain/swelling (61.9%), and airway symptoms (38.1%). Four pediatric patients (19%) reported tracheomalacia requiring tracheostomy. Pediatric patients frequently missed school because of their disease (71.4%). Surveys from 290 adult patients were compared to pediatric patients. Pediatric patients were significantly more likely to undergo biopsy (42.9% vs 17.4%; p < 0.01) and be treated with biologics (42.9% vs 19%; p = 0.02). Adults were significantly more likely to be female (87.8% vs 28.6%; p < 0.01) and to report airway symptoms (77.9% vs 47.6%; p = 0.01). Prevalence of disease complications was not significantly different between adult and pediatric patients.Conclusions.The burden of disease in pediatric patients with RP includes missed school, diagnostic delay, ER visits, and multisystem disease, with resultant damage to cartilaginous structures. Differences in airway involvement and treatment approaches may exist between pediatric and adult patients.

Dysphagia after pediatric functional hemispherectomy

2014 ◽  
Vol 13 (1) ◽  
pp. 95-100 ◽  
Author(s):  
Robert T. Buckley ◽  
Tiffany Morgan ◽  
Russell P. Saneto ◽  
Jason Barber ◽  
Richard G. Ellenbogen ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Clinical Symptoms ◽  
Intractable Epilepsy ◽  
Seizure Freedom ◽  
Postoperative Dysphagia ◽  
Duration Of Symptoms ◽  
Functional Hemispherectomy ◽  
Clinical Records ◽  
The Impact ◽  
New Onset

Object Functional hemispherectomy is a well-recognized surgical option for the treatment of unihemispheric medically intractable epilepsy. While the resultant motor deficits are a well-known and expected consequence of the procedure, the impact on other cortical functions has been less well defined. As the cortical control of swallowing would appear to be threatened after hemispherectomy, the authors retrospectively studied a pediatric population that underwent functional hemispherectomy for medically intractable epilepsy to characterize the incidence and severity of dysphagia after surgery. Methods A retrospective cohort (n = 39) of pediatric patients who underwent hemispherectomy at a single institution was identified, and available clinical records were reviewed. Additionally, the authors examined available MR images for integrity of the thalamus and basal ganglia before and after hemispherectomy. Clinical and video fluoroscopic assessments of speech pathology were reviewed, and the presence, type, and duration of pre- and postoperative dysphagia were recorded. Results New-onset, transient dysphagia occurred in 26% of patients after hemispherectomy along with worsening of preexisting dysphagia noted in an additional 15%. Clinical symptoms lasted a median of 19 days. Increased duration of symptoms was seen with late (> 14 days postoperative) pharyngeal swallow dysfunction when compared with oral dysphagia alone. Neonatal stroke as a cause for seizures decreased the likelihood of postoperative dysphagia. There was no association with seizure freedom or postoperative hydrocephalus. Conclusions New-onset dysphagia is a frequent and clinically significant consequence of hemispherectomy for intractable epilepsy in pediatric patients. This dysphagia was always self-limited except in those patients in whom preexisting dysphagia was noted.

scholarly journals Utility of N-Terminal Pro-B-Type Natriuretic Peptide to Differentiate Cardiac Diseases from Noncardiac Diseases in Young Pediatric Patients

2006 ◽  
Vol 52 (7) ◽  
pp. 1415-1419 ◽  
Author(s):  
Angelika Hammerer-Lercher ◽  
Ralf Geiger ◽  
Johannes Mair ◽  
Christoph Url ◽  
Gerald Tulzer ◽  
...  
Keyword(s):  
Natriuretic Peptide ◽  
Diagnostic Performance ◽  
Pediatric Patients ◽  
Clinical Symptoms ◽  
Linear Regression Analysis ◽  
Area Under The Curve ◽  
Cardiac Diseases ◽  
Healthy Children ◽  
Roc Curve Analysis ◽  
Diagnostic Usefulness

Abstract Background: Previous studies comparing children with cardiac disease with children with lung disease or healthy children indicated that natriuretic peptides are promising markers in pediatric patients. The aim of this study was to further clarify the diagnostic usefulness of N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurements in a less preselected population of children younger than 3 years, a population in which clinical symptoms are frequently unspecific. Methods: NT-proBNP concentrations (Roche Diagnostics) were measured in sera of 142 pediatric patients (age range, 33–1070 days) presenting at the Gynaecologic and Pediatric Hospital (Linz, Austria) between January 2003 and January 2004. ROC curve analysis for the diagnostic performance of NT-proBNP, the Mann–Whitney U-test for group comparison, and linear regression analysis for influencing factors were performed. Results: NT-proBNP concentrations were significantly increased in infants with cardiac diseases [median (25th–75th percentile), 3681 (1045–13557) ng/L; n = 23] compared with infants with other diseases [241 (116–542) ng/L; n = 119], and ROC analysis revealed good performance for NT-proBNP in differentiating between infants with and without cardiac diseases [mean area under the curve (AUC) with 95% confidence interval (CI), 0.87 (0.76–0.94)]. A subgroup analysis of exactly age- and sex-matched infants was performed, which revealed results comparable to those for the whole study population [mean (95% CI) AUC, 0.84 (0.68–0.93)]. Conclusion: In a heterogeneous group of pediatric patients &lt;3 years of age, NT-proBNP showed good diagnostic performance to distinguish between cardiac diseases and various noncardiac diseases.

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