The role of respiratory droplet physicochemistry in limiting and promoting the airborne transmission of human coronaviruses: A critical review

The article is devoted to various aspects of the use of intraluminal brachytherapy (IB) in treatment for esophageal cancer (EC). A critical review of the use of IB as a component of combined radiotherapy/chemoradiotherapy in neoadjuvant treatment regimens, for definitive CRT, as well as in palliative treatment of non-operable tumors of this localization is given. The contradictory data on the effectiveness of brachytherapy with locally distributed, inoperable EC are summarized. A separate section relates to the prospects for incorporating brachytherapy into combined treatment of early esophageal cancer. Carried out analysis testifies to the necessity of standardization of summary and daily doses of irradiation depending on the indications to the IB.

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Therapeutic role of vegetables in Respiratory Diseases – A critical review from Ayurvedic classics.

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.v1i3.4429 ◽

2016 ◽

Vol 1 (3) ◽

Author(s):

Dr. Raghavendra Naik ◽

Shweta Vekariya ◽

R. N. Acharya ◽

Sneha D. Borkar

Keyword(s):

Clinical Practice ◽

Respiratory Disease ◽

Respiratory System ◽

Critical Review ◽

Critical Analysis ◽

Respiratory Diseases ◽

Unique Contribution ◽

Pharmacological Activities ◽

The Family

The concept of Pathya (wholesome diet) is an unique contribution of Ayurveda, which plays an important role in prevention and management of many diseases. “Shakavarga”, a category under dietetics in classical texts of Ayurveda enlisted different vegetables with their properties and indications in different disease conditions. These vegetables can be prescribed as Pathya (wholesome diet) in clinical practice. In the present review, plants described under Shakavarga, indicated as Pathya in different diseases related to Pranavaha Srotas (Respiratory system) were compiled from 15 different Ayurvedic classical texts. Critical analysis of the compiled data reveals that out of 332 vegetables described under Shakavarga, 44 are indicated in respiratory disease like Shvasa (Dyspnoea/Asthma), Kasa (Cough), Peenasa (Chronic rhinitis) and Hikka (Hiccup). Among them, botanical identity of 42 classical plants has been established and maximum number of vegetables belongs to the family cucurbitaceae (10) followed by solanaceae (4). Some of these vegetables have been reported for their various pharmacological activities related to prevention and management of diseases related to Pranavaha Srotas (Respiratory system). These vegetables are reported for their anti-inflammatory (16), antioxidant (14), anti-allergic (6) and antitussive (3) activities. The observed result may be helpful in use of vegetables as Pathya (wholesome diet) and planning further scientific studies about the efficacy of these plants on prevention as well as management of respiratory diseases.

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The Seasonal End of Human Coronavirus Hospital Admissions with Implications for SARS-CoV-2 (Preprint)

10.2196/preprints.21223 ◽

2020 ◽

Author(s):

Alan T Evangelista

Keyword(s):

Hospital Admissions ◽

Disease Incidence ◽

Influenza Viruses ◽

Seasonal Effects ◽

Human Coronavirus ◽

Enveloped Virus ◽

Multiplex Pcr Assay ◽

Contact Transmission ◽

Human Coronaviruses

UNSTRUCTURED The seasonality of influenza viruses and endemic human coronaviruses was tracked over an 8-year period to assess key epidemiologic reduction points in disease incidence for an urban area in the northeast United States. Patients admitted to a pediatric hospital with worsening respiratory symptoms were tested using a multiplex PCR assay from nasopharyngeal swabs. The additive seasonal effects of outdoor temperatures and indoor relative humidity (RH) were evaluated. The 8-year average peak activity of human coronaviruses occurred in the first week of January, when droplet and contact transmission was enabled by the low indoor RH of 20-30%. Previous studies have shown that an increase in RH to 50% has been associated with markedly reduced viability and transmission of influenza virus and animal coronaviruses. As disease incidence was reduced by 50% in early March, to 75% in early April, to greater than 99% at the end of April, a relationship was observed from colder temperatures in January with a low indoor RH to a gradual increase in outdoor temperatures in April with an indoor RH of 45-50%. As a lipid-bound, enveloped virus with similar size characteristics to endemic human coronaviruses, SARS-CoV-2 should be subject to the same dynamics of reduced viability and transmission with increased humidity. In addition to the major role of social distancing, the transition from lower to higher indoor RH with increasing outdoor temperatures could have an additive effect on the decrease in SARS-CoV-2 cases in May. Over the 8-year period of this study, human coronavirus activity was either zero or >99% reduction in the months of June through September, and the implication would be that SARS-Cov-2 may follow a similar pattern. INTERNATIONAL REGISTERED REPORT RR2-doi.org/10.1101/2020.05.15.20103416

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The possible role of the Surface Active Substances (SAS) in the airborne transmission of SARS-CoV-2

Environmental Research ◽

10.1016/j.envres.2021.111215 ◽

2021 ◽

pp. 111215

Author(s):

Irena Ciglenečki ◽

Palma Orlović-Leko ◽

Kristijan Vidović ◽

Viša Tasić

Keyword(s):

Airborne Transmission ◽

Surface Active ◽

Active Substances

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A Critical Review of Computational Creativity in Built Environment Design

Buildings ◽

10.3390/buildings11010029 ◽

2021 ◽

Vol 11 (1) ◽

pp. 29

Author(s):

Ning Gu ◽

Peiman Amini Behbahani

Keyword(s):

Built Environment ◽

Critical Review ◽

Contemporary Literature ◽

Research Interest ◽

Future Research ◽

Computational Creativity ◽

Environment Design ◽

Supporting Tool ◽

Definition Of

Computational creativity in built environment (BE) design has been a subject of research interest in the discipline. This paper presents a critical review of various ways computational creativity has been and can be defined and approached in BE design. The paper examines a comprehensive body of contemporary literature on the topics of creativity, computational creativity, and their assessment to identify levels of computational creativity. The paper then proceeds to a further review of the implications of these levels specifically in BE design. The paper identifies four areas in BE design where computational creativity is relevant. In two areas—synthesis (generation) and analysis—there is considerable literature on lower levels of computational creativity. However, in two other areas—interfacing and communication—even the definition of computational creativity is not as defined and clear for the discipline, and most works only consider the role of computers as a supporting tool or medium. These open up future research opportunities for the discipline.

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