Ecotoxicity of losartan potassium in aquatic organisms of different trophic levels

2021 ◽  
Vol 87 ◽  
pp. 103727
Author(s):  
Regiane Reque ◽  
Rhaissa Dayane Carneiro ◽  
Flávia Yoshie Yamamoto ◽  
Wanessa Algarte Ramsdorf ◽  
Lucia Regina Martins ◽  
...  
1975 ◽  
Vol 189 (1096) ◽  
pp. 305-332 ◽  

A range of chlorinated hydrocarbons derived from C 1 and C 2 hydrocarbons is manufactured industrially. They are used as intermediates for further chemical manufacture and also outside the chemical industry as solvents or carriers. In the latter category losses in use are eventually dispersed to the environment. The distribution of some of these compounds, including chloroform, carbon tetrachloride, trichloroethylene, perchloroethylene and trichloroethane, in the environment (air, water and marine sediments) has been investigated and the results are presented. The concentrations found have been compared with acute toxicity levels to fish and other aquatic organisms, ascertained by laboratory bioassay. The occurrence of the compounds has been determined in a number of marine organisms, especially those at higher trophic levels, and the accumulation of some of them has been investigated in the laboratory. Chemical and microbial degradation processes have been studied in the laboratory to help determine the course of their removal from the aqueous and aerial environment, and the half lives of some of the compounds have been estimated. It is concluded that these compounds are not persistent in the environment, and that there is no significant bioaccumulation in marine food chains.


Toxics ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 261
Author(s):  
Konstantin Pikula ◽  
Mariya Tretyakova ◽  
Alexander Zakharenko ◽  
Seyed Ali Johari ◽  
Sergey Ugay ◽  
...  

Vehicle emission particles (VEPs) represent a significant part of air pollution in urban areas. However, the toxicity of this category of particles in different aquatic organisms is still unexplored. This work aimed to extend the understanding of the toxicity of the vehicle exhaust particles in two species of marine diatomic microalgae, the planktonic crustacean Artemia salina, and the sea urchin Strongylocentrotus intermedius. These aquatic species were applied for the first time in the risk assessment of VEPs. Our results demonstrated that the samples obtained from diesel-powered vehicles completely prevented egg fertilization of the sea urchin S. intermedius and caused pronounced membrane depolarization in the cells of both tested microalgae species at concentrations between 10 and 100 mg/L. The sample with the highest proportion of submicron particles and the highest content of polycyclic aromatic hydrocarbons (PAHs) had the highest growth rate inhibition in both microalgae species and caused high toxicity to the crustacean. The toxicity level of the other samples varied among the species. We can conclude that metal content and the difference in the concentrations of PAHs by itself did not directly reflect the toxic level of VEPs, but the combination of both a high number of submicron particles and high PAH concentrations had the highest toxic effect on all the tested species.


2020 ◽  
Vol 31 (9) ◽  
pp. 655-675
Author(s):  
F. Lunghini ◽  
G. Marcou ◽  
P. Azam ◽  
M.H. Enrici ◽  
E. Van Miert ◽  
...  

Nanomaterials ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 1126 ◽  
Author(s):  
Nemi Malhotra ◽  
Tzong-Rong Ger ◽  
Boontida Uapipatanakul ◽  
Jong-Chin Huang ◽  
Kelvin H.-C. Chen ◽  
...  

This review summarizes the present knowledge on the toxicity of copper and copper nanoparticles (CuNPs) to various fish species. In previous decades, the excessive usage of metal and metallic nanoparticles has increased significantly, increasing the probability of the accumulation and discharge of metals in various trophic levels of the environment. Due to these concerns, it is important to understand the toxicity mechanisms of metals and metallic nanoparticles before they lead to unhealthy effects on human health. In this review paper, we specifically focus on the effect of metal copper and CuNPs on different fish organs under different physiochemical parameters of various water bodies. Nowadays, different forms of copper have distinctive and specific usages, e.g., copper sulfate is a well-established pesticide which is used to control the growth of algae in lakes and ponds. Deactivating the fungi enzymes prevents fungal spores from germinating. This process of deactivation is achieved via the free cupric ions, which are established as the most toxic forms of copper. Complexes of copper with other ligands may or may not be bioavailable for use in aquatic organisms. On the other hand, CuNPs have shown cost-effectiveness and numerous promising uses, but the toxicity and availability of copper in a nanoparticle form is largely unknown, Additionally, physiochemical factors such as the hardness of the water, alkalinity, presence of inorganic and organic ligands, levels of pH, and temperature in various different water bodies affect the toxicity caused by copper and CuNPs. However, comprehensive knowledge and data regarding the pattern of toxicity for copper metal ions and CuNPs in marine organisms is still limited. In this review, we carry out a critical analysis of the availability of the toxicological profiles of copper metal ions and CuNPs for different fishes in order to understand the toxicity mechanisms of copper and CuNPs. We believe that this review will provide valuable information on the toxicological profile of copper, which will further help in devising safe guidelines for the usage of copper and CuNPs in a sustainable manner.


2010 ◽  
Vol 96 (4) ◽  
pp. 290-297 ◽  
Author(s):  
Sónia P.M. Ventura ◽  
Ana M.M. Gonçalves ◽  
Fernando Gonçalves ◽  
João A.P. Coutinho

2009 ◽  
Vol 2 (3) ◽  
pp. 177-183 ◽  
Author(s):  
Jana Kovářová ◽  
Zdeňka Svobodová

Can thiol compounds be used as biomarkers of aquatic ecosystem contamination by cadmium?Due to anthropogenic activities, heavy metals still represent a threat for various trophic levels. If aquatic animals are exposed to heavy metals we can obviously observe considerable toxicity. It is well known that an organism affected by cadmium (Cd) synthesize low molecular mass thiol compounds rich in cysteine (Cys), such as metallothioneins (MT) and glutathione (GSH/GSSG). The aim of this study was to summarize the effect of Cd on level of thiol compounds in aquatic organisms, and evaluate that the concentrations of thiol compounds are effective indicators of Cd water pollution and explain their potential use in biomonitoring applications.


2015 ◽  
Vol 2015 ◽  
pp. 1-19 ◽  
Author(s):  
Lungile P. Lukhele ◽  
Bhekie B. Mamba ◽  
Ndeke Musee ◽  
Victor Wepener

This study investigated the toxicity of double walled carbon nanotubes (DWCNTs) to three aquatic organisms, namely,Pseudokirchneriella subcapitata,Daphnia pulex, andPoecilia reticulataunder the influence of exposure media properties specifically the ionic strength and organic matter represented by humic acid. Results indicated that ionic strength enhanced DWCNTs agglomeration whilst humic acid stabilized the CNTs and in turn inhibited the formation of aggregates. LC50s forD. pulexwere higher at 2.81 and 4.45 mg/L for pristine and oxidised DWCNTs, respectively; however,P. reticulatahad lower values of 113.64 mg/L and 214.0 mg/L for the same CNTs correspondingly.P. subcapitatahad EC50s of 17.95 mg/L and 10.93 mg/L for the pristine and oxidised DWCNTs, respectively. In the presence of humic acid high DWCNTs acute toxicity towardsD. pulexandP. reticulatawas observed but ionic strength led to opposite effect irrespective of DWCNTs form. Both humic acid and ionic strength shielded theP. subcapitatafrom toxic effects of DWCNTs. Overall, our findings suggest that the toxicity of DWCNTs in the aquatic systems (i) will be dependent on media properties and (ii) is likely to proceed at different rates to organisms at different trophic levels.


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