The role of specific early trauma in adult depression: A meta-analysis of published literature. Childhood trauma and adult depression

2015 ◽  
Vol 30 (6) ◽  
pp. 665-680 ◽  
Author(s):  
L. Mandelli ◽  
C. Petrelli ◽  
A. Serretti
Keyword(s):  
Physical Abuse ◽  
Childhood Trauma ◽  
Emotional Abuse ◽  
Depressive Disorders ◽  
Meta Analysis ◽  
Adult Life ◽  
Adult Depression ◽  
Childhood Traumas ◽  
Post Hoc

AbstractBackgroundA large literature has long focused on the role of trauma in childhood and risk for psychological disorders in adulthood. Despite several studies performed, to date, it is not clear which weight have different childhood stressors specifically on the risk for depression in adult life. In the present study, we performed a meta-analysis of the literature in order to assess the effective role of childhood traumas as risk factor in the onset of depressive disorders in adults.MethodsPreviously published papers investigating the exposure to childhood trauma and their association with depression in adult subjects were retrieved in literature through common databases. Meta-analysis was conducted by the RevMan software. The quality of studies was evaluated by an adapted version of the New-Ottawa Quality Assessment Scale; bias publication was evaluated by the Egger's test. Meta-regression analysis was employed to detect potential confounders and/or moderating variables. Finally, a sensitivity analysis was post-hoc performed to control for potential confounders.ResultsEmotional abuse showed the strongest association with depression (OR = 2.78) followed by neglect (OR = 2.75) and sexual abuse (OR = 2.42). Significant associations were also found for domestic violence (OR = 2.06) and physical abuse (OR = 1.98). Nevertheless, in post-hoc analysis, emotional abuse and neglect showed the strongest associations with depression as compared to other kinds of child trauma.ConclusionsThese findings support the role of neglect and emotional abuse as significantly associated to depression. Sexual/physical abuse or violence in family may be unspecific risk factors for mental disturbance. Other kind of trauma may play a less relevant role in risk of adult depression, though they should be not underestimated.

scholarly journals A Meta-Analysis of Childhood Maltreatment in Relation to Psychopathic Traits

2021 ◽  
Author(s):  
Corine de Ruiter ◽  
Matthias Burghart ◽  
Raneesha De Silva ◽  
Sara Griesbeck Garcia ◽  
Ushna Mian ◽  
...  
Keyword(s):  
Physical Abuse ◽  
Childhood Maltreatment ◽  
Emotional Abuse ◽  
Complex Trauma ◽  
Meta Analysis ◽  
Therapeutic Interventions ◽  
Effect Sizes ◽  
Social Deviance ◽  
Abuse And Neglect

Psychopathy is a personality disorder characterized by a mix of traits belonging to four facets: affective (e.g., callous/lack of empathy), interpersonal (e.g., grandiosity), behavioral instability (e.g., impulsivity, poor behavioral controls), and social deviance (e.g., juvenile delinquency, criminal versatility). Several scholars have argued that early childhood maltreatment impacts the development of psychopathy, although views regarding its role in the four facets differ. We conducted a meta-analysis including 47 studies comprising a total of 349 effect sizes and 12,737 participants, to investigate the association between the four psychopathy facets and four types of child maltreatment: physical abuse, emotional abuse, neglect, and sexual abuse.We found support for a moderate link between overall psychopathy and childhood physical abuse, emotional abuse, and neglect, as well as overall childhood maltreatment. The link between psychopathy and childhood sexual abuse was small, but still significant. These associations were stronger for the behavioral and antisocial facets than for the affective and interpersonal facets of psychopathy, but nearly all associations were significant. Our findings are consistent with recently developed theories on the role of complex trauma in the development of severe personality disorders. Trauma-focused preventive and therapeutic interventions can provide further tests of the trauma-psychopathy hypothesis.

Clinical Course and Clinical Features in MDD Patients: General and Specific Role of Subtypes of Childhood Trauma: 重性抑郁障碍患者的临床病程及特征：一般及特定童年创伤亚型的作用

2021 ◽  
pp. 001100002199593
Author(s):  
Xianbin Li ◽  
Tony Xing Tan ◽  
Qijing Bo ◽  
Zhen Mao ◽  
Feng Li ◽  
...  
Keyword(s):  
Physical Abuse ◽  
Childhood Trauma ◽  
Emotional Abuse ◽  
Age Of Onset ◽  
Linear Modeling ◽  
Childhood Trauma Questionnaire ◽  
Diagnostic And Statistical Manual ◽  
Clinical Presentations ◽  
Younger Age

Our study focused on childhood emotional neglect and several forms of abuse (i.e., physical, sexual, and emotional) and the diagnosis and clinical courses of disease in Chinese adults with major depressive disorder (MDD), including MDD with anxiety, with suicidality, and with other presentations. MDD and other clinical presentations were determined with the American Psychiatric Association’s (2000) Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV) and subtypes of trauma were assessed with the Childhood Trauma Questionnaire (95 patients and 94 comparisons). Patients with MDD and suicidality scored higher on childhood emotional abuse and neglect than other MDD patients. Both emotional abuse and physical abuse correlated with a younger age of onset and more relapses of MDD. General linear modeling also showed that controlling for demographic variables, emotional and physical abuse predicted more MDD relapses. Overall, childhood trauma was correlated with a MDD diagnosis, the role of specific types of trauma in the clinical courses of MDD varied.

scholarly journals Effect of childhood trauma on disease severity in patients with fibromyalgia: The mediating role of psychological resilience

2021 ◽  
Vol 36 (4) ◽  
pp. 538-547
Author(s):  
Özlem Kazan Kızılkurt ◽  
Arda Kazım Demirkan ◽  
Ferzan Ergün Gıynaş ◽  
Hüseyin Güleç
Keyword(s):  
Physical Abuse ◽  
Disease Severity ◽  
Childhood Trauma ◽  
Emotional Abuse ◽  
Fibromyalgia Impact Questionnaire ◽  
Mediating Effect ◽  
Psychological Resilience ◽  
Mediating Role ◽  
Physical Neglect

Objectives: This study aims to investigate the effect of childhood traumas on the disease severity in fibromyalgia and evaluate the mediating role of psychological resilience in this effect. Patients and methods: Between June 2017 and January 2018, this study included a total of 80 female patients (mean age: 31.9±4.0 years; range, 20 to 40 years) with fibromyalgia according to the 2010 American College of Rheumatology fibromyalgia diagnostic criteria. All patients were evaluated using the sociodemographic data form, Resilience Scale for Adults (RSA), Childhood Trauma Questionnaire (CTQ), and Fibromyalgia Impact Questionnaire (FIQ). Results: A positive correlation was observed between the FIQ and CTQ total scores, emotional abuse, physical abuse, and physical neglect scores. The FIQ was negatively correlated with the RSA scores. Path analysis conducted to evaluate mediating effect of psychological resilience revealed that psychological resilience had a mediator role in the correlation between FIQ and emotional abuse, physical abuse, and physical neglect scores. Conclusion: The main finding of this study is the protective effect of psychological resilience -improvable capacity to cope with early life traumas- on fibromyalgia symptoms that leads to negative functioning of several aspects.

scholarly journals Deconstructing Vulnerability for Psychosis: Meta-Analysis of Environmental Risk Factors for Psychosis in Subjects at Ultra High-Risk

2016 ◽  
Vol 40 ◽  
pp. 65-75 ◽  
Author(s):  
P. Fusar-Poli ◽  
M. Tantardini ◽  
S. De Simone ◽  
V. Ramella-Cravaro ◽  
D. Oliver ◽  
...  
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Childhood Trauma ◽  
Environmental Risk ◽  
Emotional Abuse ◽  
Meta Analysis ◽  
Environmental Risk Factors ◽  
Ultra High Risk ◽  
Physical Neglect

AbstractBackgroundSubjects at ultra high-risk (UHR) for psychosis have an enhanced vulnerability to develop the disorder but the risk factors accounting for this accrued risk are undetermined.MethodSystematic review of associations between genetic or environmental risk factors for psychosis that are widely established in the literature and UHR state, based on comparisons to controls.ResultsForty-four studies encompassing 170 independent datasets and 54 risk factors were included. There were no studies on association between genetic or epigenetic risk factors and the UHR state that met the inclusion criteria. UHR subjects were more likely to show obstetric complications, tobacco use, physical inactivity, childhood trauma/emotional abuse/physical neglect, high perceived stress, childhood and adolescent low functioning, affective comorbidities, male gender, single status, unemployment and low educational level as compared to controls.ConclusionsThe increased vulnerability of UHR subjects can be related to environmental risk factors like childhood trauma, adverse life events and affective dysfunction. The role of genetic and epigenetic risk factors awaits clarification.

scholarly journals Childhood Trauma Is Associated with the Spirituality of Non-Religious Respondents

2020 ◽  
Vol 17 (4) ◽  
pp. 1268 ◽  
Author(s):  
Alice Kosarkova ◽  
Klara Malinakova ◽  
Zuzana Koncalova ◽  
Peter Tavel ◽  
Jitse P. van Dijk
Keyword(s):  
Childhood Trauma ◽  
Emotional Abuse ◽  
Therapeutic Process ◽  
Adult Life ◽  
Spiritual Needs ◽  
Psychotherapeutic Treatment ◽  
The Czech Republic ◽  
Positive Coping ◽  
Conversion Experience ◽  
Nationally Representative

Childhood trauma experience (CT) is negatively associated with many aspects of adult life. Religiosity/spirituality (R/S) are often studied as positive coping strategies and could help in the therapeutic process. Evidence on this is lacking for a non-religious environment. The aim of this study was to assess the associations of different types of CT with R/S in the secular conditions of the Czech Republic. A nationally representative sample (n = 1800, mean age = 46.4, SD = 17.4; 48.7% male) of adults participated in the survey. We measured childhood trauma, spirituality, religiosity and conversion experience. We found that four kinds of CT were associated with increased levels of spirituality, with odds ratios (OR) ranging from 1.17 (95% confidence interval 1.03–1.34) to 1.31 (1.18–1.46). Non-religious respondents were more likely to report associations of CT with spirituality. After measuring for different combinations of R/S, each CT was associated with increased chances of being “spiritual but non-religious”, with OR from 1.55 (1.17–2.06) to 2.10 (1.63–2.70). Moreover, converts were more likely to report emotional abuse OR = 1.46 (1.17–1.82) or emotional neglect with OR = 1.42 (1.11–1.82). Our findings show CT is associated with higher levels of spirituality in non-religious respondents. Addressing spiritual needs may contribute to the effectiveness of psychotherapeutic treatment of the victims.

The role of overgeneral autobiographical memory in the development of adult depression following childhood trauma

2004 ◽  
Vol 43 (4) ◽  
pp. 365-376 ◽  
Author(s):  
Elizabeth Burnside ◽  
Mike Startup ◽  
Marie Byatt ◽  
Lynn Rollinson ◽  
Jonathan Hill
Keyword(s):  
Autobiographical Memory ◽  
Childhood Trauma ◽  
Overgeneral Autobiographical Memory ◽  
Adult Depression

Childhood adversities in people at ultra-high risk (UHR) for psychosis: a systematic review and meta-analysis

2019 ◽  
Vol 49 (07) ◽  
pp. 1089-1101 ◽  
Author(s):  
Oon Him Peh ◽  
Attilio Rapisarda ◽  
Jimmy Lee
Keyword(s):  
High Risk ◽  
Childhood Trauma ◽  
Emotional Abuse ◽  
Meta Analysis ◽  
Future Research ◽  
Parental Separation ◽  
Childhood Adversities ◽  
Cross Sectional ◽  
Ultra High Risk ◽  
Bullying Victimisation

AbstractChildhood adversities have been reported to be more common among individuals at ultra-high risk (UHR) for psychosis. This paper systematically reviewed and meta-analysed (i) the severity and prevalence of childhood adversities (childhood trauma exposure, bullying victimisation and parental separation or loss) among the UHR, and (ii) the association between adversities and transition to psychosis (TTP). PsycINFO, PubMed and Embase databases were searched for studies reporting childhood adversities among UHR individuals. Only published articles were included. Risk of bias was assessed using Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guideline (von Elm et al., 2007) and the tool developed by Hoy et al. (2012). Seventeen case–control, cross-sectional and longitudinal studies were included. UHR individuals experienced significantly more severe trauma than controls, regardless of trauma subtype. UHR were 5.5, 2.5 and 3.1 times as likely to report emotional abuse, physical abuse and bullying victimisation, respectively. There was no association with parental separation. However, childhood trauma was not significantly associated with TTP (follow-up periods: 6 months to 15 years), suggesting that trauma alone may not be a sufficient risk factor. Sexual abuse was associated with TTP but this may have been driven by a single large study. Potential confounders and low rates of TTP among UHR are limitations of this review. This is the first meta-analysis that quantitatively summarises the associations between childhood adversities and TTP among UHR, and between specific abuse subtypes and TTP. Specific recommendations have been made to increase the quality of future research. PROSPERO registration no. CRD42017054884.

scholarly journals Role of Omega-3 Fatty Acids in the Treatment of Depressive Disorders: A Comprehensive Meta-Analysis of Randomized Clinical Trials

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e96905 ◽  
Author(s):  
Giuseppe Grosso ◽  
Andrzej Pajak ◽  
Stefano Marventano ◽  
Sabrina Castellano ◽  
Fabio Galvano ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Clinical Trials ◽  
Depressive Disorders ◽  
Randomized Clinical Trials ◽  
Meta Analysis ◽  
Omega 3 Fatty Acids ◽  
Omega 3

Childhood Trauma in Bipolar Disorders: Familial and Individual Mediators for Predicting Occurrence and Outcome

2017 ◽  
Vol 41 (S1) ◽  
pp. S28-S28
Author(s):  
B. Etain
Keyword(s):  
Physical Abuse ◽  
Childhood Trauma ◽  
Emotional Abuse ◽  
Suicide Attempts ◽  
Bipolar Disorders ◽  
Affect Intensity ◽  
The Face ◽  
History Of ◽  
Competing Interest ◽  
Psychotic Features

Childhood trauma is highly prevalent in patients with bipolar disorder (BD) and has been associated to a more severe/complex expression of the disorder. Little is known about the familial and individual factors that can mediate the occurrence of trauma within families but also influence the outcomes of BD. We will present data from two independent samples of patients with BD in order to identify the potential mediators for occurrence and severity/complexity. In a first sample of 371 patients with BD, 256 relatives and 157 healthy controls, we will show that there is a familial resemblance for emotional and physical abuses. Patients’ level of physical abuse was associated with their parental levels of physical abuse, but also with their father's history of alcohol misuse (p < 0.05). Second, in a sub-sample of 270 normothymic patients, we have performed a path-analysis to demonstrate that emotional and physical abuses interacted with cannabis misuse to increase the frequency of psychotic features and delusional beliefs. Finally, in an independent sample of 485 euthymic patients from the FACE-BD cohort we used path-analytic models to show that emotional abuse increased all the assessed affective/impulsive dimensions (p < 0.001). In turn, affect intensity and attitudinal hostility were associated with high risk for suicide attempts (p < 0.001), whereas impulsivity was associated with a higher risk for presence of substance misuse (p < 0.001). These results illustrate that childhood trauma might derive from parental characteristics (own childhood trauma and psychopathology) and increase the severity/complexity of BD through individual dimensions of psychopathology.Disclosure of interestThe author has not supplied his declaration of competing interest.

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