Myomectomy for a large uterine fibroid via mini-laparotomy: a step-by-step video tutorial

2021 ◽  
Author(s):  
Lejla Sandrieser ◽  
Lorenz Kuessel ◽  
Alexandra Perricos ◽  
René Wenzl ◽  
Heinrich Husslein
Keyword(s):  
Uterine Fibroid ◽  
Video Tutorial ◽  
Mini Laparotomy

Pengembangan Media Pembelajaran Audio Visual Dengan Teknik Tutorial Berbasis Kemampuan Konseptual Pada Mata Pelajaran Integral

2019 ◽  
Vol 6 (1) ◽  
pp. 25-31
Author(s):  
Ledi Diana ◽  
Anggita Maharani
Keyword(s):  
Video Tutorial

Media pembelajaran merupakan alat bantu yang berfungsi  untuk menjelaskan sebagian dari keseluruhan program pembelajaran yang sulit dijelaskan seecara verbal ( Musfiqon, dalam Okto Ardiansyah, 2012). Matematika seringkali dianggap suatu hal yang menakutkan dikalangan siswa di sekolah karena identik dengan banyaknya konsep, khususnya pada materi integral dimana materi tersebut baru diperkenalkan pada siswa SMA sehingga siswa banyak yang mengalami kesulitan bahkan seringkali dirasakan sangat absrak sehingga dirasa kurang ada manfaatnya di kehidupan sehari-hari. Artikel ini merupakan hasil penelitian pengembangan produk dalam bentuk video tutorial pada materi integral untuk siswa SMA. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian pengembangan. Penelitian ini memenfaatkan video tutorial sebagai media pembeajaran. Instrumen yang digunakan dalam penelitian ini adalah lembar penelitan ahli materi dan media terhadapmedia pembelajaran. Setelah media pembelejaran dibuat selanjutnya divalidasi oleh  tim ahli. Validasi dilakukan oleh satu ahli materi dan  ahi desain. Setelah media divalidasi dan direvisi kembali menemukan kelemahan maka selanjutnya akan diuji coba penggunaanya. Dari hasil analisis validasi terhadap video tutorial pada materi integral diperoleh 81,25. Ini artinya mediapembelajaran yang telah dibuat sesuai dengan tujuan penggunaan mediapembelajaran. Sehingga media pembelajaran ini bisa digunakan oleh guru Matematika SMA  khususnya pada pembelajaran materi integral. Kata Kunci: video tutorial, kemampuan konseptual

Women’s Infertility - A Ayurvedic thought

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Sonalika Hiremath ◽  
Santhosh Kumar S. ◽  
Sridevi Swamy
Keyword(s):  
Uterine Fibroid ◽  
Poor Quality ◽  
The State ◽  
Full Term ◽  
Female Infertility ◽  
Cervical Canal ◽  
Fallopian Tubes ◽  
Structural Problems ◽  
Hormonal Imbalance ◽  
Males And Females

Infertility primarily refers to the biological inability of a person to contribute to conception. In women, it may also refer to the state when she is not able to carry a pregnancy to its full term. Female infertility is caused due to structural problems like blocked Fallopian tubes, defect in cervical canal, uterine fibroid or polyps. Hormonal imbalance leading .ovulation problems too can cause infertility. From Ayurvedic perspectives, Shukra Dhatu can get affected by various physical, mental causes and even by serious diseases. Poor quality Shukra Dhatu can cause infertility in males and females.

scholarly journals Validation of a menstrual pictogram and a daily bleeding diary for assessment of uterine fibroid treatment efficacy in clinical studies

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Claudia Haberland ◽  
Anna Filonenko ◽  
Christian Seitz ◽  
Matthias Börner ◽  
Christoph Gerlinger ◽  
...  
Keyword(s):  
Uterine Fibroid ◽  
Full Range ◽  
Intraclass Correlation ◽  
Phase Iii ◽  
Measurement Properties ◽  
Retest Reliability ◽  
Response Options ◽  
Patient Global Impression ◽  
Patient Reported ◽  
Test Retest Reliability

Abstract Background To evaluate the psychometric and measurement properties of two patient-reported outcome instruments, the menstrual pictogram superabsorbent polymer-containing version 3 (MP SAP-c v3) and Uterine Fibroid Daily Bleeding Diary (UF-DBD). Test-retest reliability, criterion, construct validity, responsiveness, missingness and comparability of the MP SAP-c v3 and UF-DBD versus the alkaline hematin (AH) method and a patient global impression of severity (PGI-S) were analyzed in post hoc trial analyses. Results Analyses were based on data from up to 756 patients. The full range of MP SAP-c v3 and UF-DBD response options were used, with score distributions reflecting the cyclic character of the disease. Test-retest reliability of MP SAP-c v3 and UF-DBD scores was supported by acceptable intraclass correlation coefficients when stability was defined by the AH method and Patient Global Impression of Severity (PGI-S) scores (0.80–0.96 and 0.42–0.94, respectively). MP SAP-c v3 and UF-DBD scores demonstrated strong and moderate-to-strong correlations with menstrual blood loss assessed by the AH method. Scores increased in monotonic fashion, with greater disease severities, defined by the AH method and PGI-S scores; differences between groups were mostly statistically significant (P < 0.05). MP SAP-c v3 and UF-DBD were sensitive to changes in disease severity, defined by the AH method and PGI-S. MP SAP-c v3 and UF-DBD showed a lower frequency of missing patient data versus the AH method, and good agreement with the AH method. Conclusions This evidence supports the use of the MP SAP-c v3 and UF-DBD to assess clinical efficacy endpoints in UF phase III studies replacing the AH method.

scholarly journals Transcriptome Analyses of Myometrium from Fibroid Patients Reveals Phenotypic Differences Compared to Non-Diseased Myometrium

2021 ◽  
Vol 22 (7) ◽  
pp. 3618
Author(s):  
Emmanuel N. Paul ◽  
Gregory W. Burns ◽  
Tyler J. Carpenter ◽  
Joshua A. Grey ◽  
Asgerally T. Fazleabas ◽  
...  
Keyword(s):  
Uterine Fibroid ◽  
Three Dimensional ◽  
Uterine Fibroids ◽  
Principal Component ◽  
Leading Edge ◽  
Gene Set Enrichment ◽  
Phenotypic Differences ◽  
False Discovery ◽  
Gene Sets ◽  
High Concordance

Uterine fibroid tissues are often compared to their matched myometrium in an effort to understand their pathophysiology, but it is not clear whether the myometria of uterine fibroid patients represent truly non-disease control tissues. We analyzed the transcriptomes of myometrial samples from non-fibroid patients (M) and compared them with fibroid (F) and matched myometrial (MF) samples to determine whether there is a phenotypic difference between fibroid and non-fibroid myometria. Multidimensional scaling plots revealed that M samples clustered separately from both MF and F samples. A total of 1169 differentially expressed genes (DEGs) (false discovery rate < 0.05) were observed in the MF comparison with M. Overrepresented Gene Ontology terms showed a high concordance of upregulated gene sets in MF compared to M, particularly extracellular matrix and structure organization. Gene set enrichment analyses showed that the leading-edge genes from the TGFβ signaling and inflammatory response gene sets were significantly enriched in MF. Overall comparison of the three tissues by three-dimensional principal component analyses showed that M, MF, and F samples clustered separately from each other and that a total of 732 DEGs from F vs. M were not found in the F vs. MF, which are likely understudied in the pathogenesis of uterine fibroids and could be key genes for future investigation. These results suggest that the transcriptome of fibroid-associated myometrium is different from that of non-diseased myometrium and that fibroid studies should consider using both matched myometrium and non-diseased myometrium as controls.

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