scholarly journals Corrigendum to “Modification of coffee coproducts by dynamic high pressure, acetylation and hydrolysis by cellulase: A potential functional and sustainable food ingredient” [Innovative Food Science and Emerging Technologies 68 (2021) 102608]

Author(s):  
Ricardo Henrique Belmiro ◽  
Ludmilla de Carvalho Oliveira ◽  
Marina Vilar Geraldi ◽  
M'ario Roberto Marostica ◽  
Marcelo Cristianini
Author(s):  
Dominic Rovai ◽  
Elizabeth Michniuk ◽  
Elizabeth Roseman ◽  
Samir Amin ◽  
Ruta Lesniauskas ◽  
...  

2018 ◽  
Vol 216 ◽  
pp. 90-97 ◽  
Author(s):  
Wei Zhang ◽  
Fan Xie ◽  
Xiaohong Lan ◽  
Shengxiang Gong ◽  
Zhengwu Wang

2021 ◽  
Vol 22 (18) ◽  
pp. 9896
Author(s):  
Eugenia Romano ◽  
Paolo Antonio Netti ◽  
Enza Torino

In recent decades, endogenous nanocarrier-exosomes have received considerable scientific interest as drug delivery systems. The unique proteo-lipid architecture allows the crossing of various natural barriers and protects exosomes cargo from degradation in the bloodstream. However, the presence of this bilayer membrane as well as their endogenous content make loading of exogenous molecules challenging. In the present work, we will investigate how to promote the manipulation of vesicles curvature by a high-pressure microfluidic system as a ground-breaking method for exosomes encapsulation. Exosomes isolated from Uppsala 87 Malignant Glioma (U87-MG) cell culture media were characterized before and after the treatment with high-pressure homogenization. Once their structural and biological stability were validated, we applied this novel method for the encapsulation in the lipidic exosomal bilayer of the chemotherapeutic Irinotecan HCl Trihydrate-CPT 11. Finally, we performed in vitro preliminary test to validate the nanobiointeraction of exosomes, uptake mechanisms, and cytotoxic effect in cell culture model.


2021 ◽  
pp. 145-153
Author(s):  
Sven Karlović ◽  
Tomislav Bosiljkov ◽  
Damir Ježek ◽  
Marinela Nutrizio ◽  
Anet Režek Jambrak

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