A design optimization study on synthesized nanocrystalline cellulose, evaluation and surface modification as a potential biomaterial for prospective biomedical applications

2018 ◽  
Vol 114 ◽  
pp. 536-546 ◽  
Author(s):  
Fahanwi Asabuwa Ngwabebhoh ◽  
Ahmet Erdem ◽  
Ufuk Yildiz
Keyword(s):  
Surface Modification ◽  
Design Optimization ◽  
Biomedical Applications ◽  
Nanocrystalline Cellulose ◽  
Optimization Study

Development of a flexible design optimization study tool

1998 ◽  
Author(s):  
Dipankar Ghosh ◽  
John Garcelon ◽  
Vladimir Balabanov ◽  
Garret Vanderplaats
Keyword(s):  
Design Optimization ◽  
Flexible Design ◽  
Optimization Study

scholarly journals Hybrid Seven-bar Press Mechanism

2018 ◽  
Vol 12 (3) ◽  
pp. 181-187
Author(s):  
M. Erkan Kütük ◽  
L. Canan Dülger
Keyword(s):  
Genetic Algorithm ◽  
Objective Function ◽  
Design Optimization ◽  
Hybrid System ◽  
Degrees Of Freedom ◽  
Dimensional Synthesis ◽  
Design Variables ◽  
Optimization Study ◽  
Metal Stamping

An optimization study with kinetostatic analysis is performed on hybrid seven-bar press mechanism. This study is based on previous studies performed on planar hybrid seven-bar linkage. Dimensional synthesis is performed, and optimum link lengths for the mechanism are found. Optimization study is performed by using genetic algorithm (GA). Genetic Algorithm Toolbox is used with Optimization Toolbox in MATLAB®. The design variables and the constraints are used during design optimization. The objective function is determined and eight precision points are used. A seven-bar linkage system with two degrees of freedom is chosen as an example. Metal stamping operation with a dwell is taken as the case study. Having completed optimization, the kinetostatic analysis is performed. All forces on the links and the crank torques are calculated on the hybrid system with the optimized link lengths

scholarly journals Water uptake of various electrospun nonwovens

2020 ◽  
Vol 6 (3) ◽  
pp. 155-158
Author(s):  
Katharina Wulf ◽  
Volkmar Senz ◽  
Thomas Eickner ◽  
Sabine Illner
Keyword(s):  
Contact Angle ◽  
Surface Modification ◽  
Water Absorption ◽  
Water Uptake ◽  
Biomedical Applications ◽  
High Surface ◽  
Volume Ratio ◽  
Polymer Composition ◽  
Water Wetting ◽  
Morphology Changes

AbstractIn recent years, nanofiber based materials have emerged as especially interesting for several biomedical applications, regarding their high surface to volume ratio. Due to the superficial nano- and microstructuring and the different wettability compared to nonstructured surfaces, the water absorption is an important parameter with respect to the degradation stability, thermomechanic properties and drug release properties, depending on the type of polymer [1]. In this investigation, the water absorption of different non- and plasma modified biostable nanofiber nonwovens based on polyurethane, polyester and polyamide were analysed and compared. Also, the water absorption by specified water wetting, the contact angle and morphology changes were examined. The results show that the water uptake is highly dependent on the surface modification and the polymer composition itself and can therefore be partially changed.

scholarly journals Surface modification of cellulose nanocrystals

Nanoscale ◽  
2014 ◽  
Vol 6 (14) ◽  
pp. 7764-7779 ◽  
Author(s):  
Samuel Eyley ◽  
Wim Thielemans
Keyword(s):  
Surface Modification ◽  
Cellulose Nanocrystals ◽  
Nanocrystalline Cellulose ◽  
Chemical Modifications

This review takes an in-depth look at the chemical modifications that have been carried out on nanocrystalline cellulose.

scholarly journals Topographical and Biomechanical Guidance of Electrospun Fibers for Biomedical Applications

Polymers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 2896
Author(s):  
Sara Ferraris ◽  
Silvia Spriano ◽  
Alessandro Calogero Scalia ◽  
Andrea Cochis ◽  
Lia Rimondini ◽  
...  
Keyword(s):  
Surface Modification ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Electrospun Fibers ◽  
Natural Polymers ◽  
Polymeric Fibers ◽  
Biological Phenomena ◽  
Proper Design ◽  
Synthetic And Natural Polymers ◽  
Selection Of

Electrospinning is gaining increasing interest in the biomedical field as an eco-friendly and economic technique for production of random and oriented polymeric fibers. The aim of this review was to give an overview of electrospinning potentialities in the production of fibers for biomedical applications with a focus on the possibility to combine biomechanical and topographical stimuli. In fact, selection of the polymer and the eventual surface modification of the fibers allow selection of the proper chemical/biological signal to be administered to the cells. Moreover, a proper design of fiber orientation, dimension, and topography can give the opportunity to drive cell growth also from a spatial standpoint. At this purpose, the review contains a first introduction on potentialities of electrospinning for the obtainment of random and oriented fibers both with synthetic and natural polymers. The biological phenomena which can be guided and promoted by fibers composition and topography are in depth investigated and discussed in the second section of the paper. Finally, the recent strategies developed in the scientific community for the realization of electrospun fibers and for their surface modification for biomedical application are presented and discussed in the last section.

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