Structural features and antioxidant activities of Chinese quince (Chaenomeles sinensis) fruits lignin during auto-catalyzed ethanol organosolv pretreatment

Three pretreatments, including sugar removal, dephenolization and multiple processes, are applied on the lignin extraction from Chinese quince fruits.

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Effect of drying pretreatment methods on structural features and antioxidant activities of Brauns native lignin extracted from Chinese quince fruit

Process Biochemistry ◽

10.1016/j.procbio.2021.04.004 ◽

2021 ◽

Vol 106 ◽

pp. 70-77

Author(s):

Xi-Chuang Cheng ◽

Xin-Yu Cui ◽

Zhao Qin ◽

Hua-Min Liu ◽

Xue-De Wang ◽

...

Keyword(s):

Antioxidant Activities ◽

Structural Features ◽

Chinese Quince

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Fast Screening for Antioxidant Properties of Flavonoids from Pterogyne nitens Using Electrochemical Methods

Journal of AOAC International ◽

10.5740/jaoacint.11-137 ◽

2012 ◽

Vol 95 (3) ◽

pp. 773-777 ◽

Cited By ~ 1

Author(s):

Leonardo Luiz Okumura ◽

Luis Octávio Regasini Regasini ◽

Daniara Cristina Fernandes ◽

Dulce Helena Siqueira da Silva ◽

Maria Valnice Boldrin Zanoni ◽

...

Keyword(s):

Antioxidant Activities ◽

Low Cost ◽

Supporting Electrolyte ◽

Antioxidant Properties ◽

Reference Electrode ◽

Structural Features ◽

Quantitative Detection ◽

Nonaqueous Media ◽

Electrochemical Detector ◽

Fast Screening

Abstract A fast, low-cost, convenient, and especially sensitive voltammetric screening approach for the study of the antioxidant properties of isoquercitrin and pedalitin from Pterogyne nitens is suggested in this work. These flavonoids were investigated for their redox properties using cyclic voltammetry in nonaqueous media using N,N-dimethylformamide and tetrabutylammonium tetrafluorborate as the supporting electrolyte, a glassy carbon working electrode, Ag|AgCl reference electrode, and Pt bare wire counter electrode. The comparative analysis of the activity of rutin has also been carried out. Moreover, combining HPLC with an electrochemical detector allowed qualitative and quantitative detection of micromolecules (e.g., isoquercitrin and pedalitin) that showed antioxidant activities. These results were then correlated to the inhibition of β-carotene bleaching determined by TLC autographic assay and to structural features of the flavonoids.

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Efficient Synthesis of Novel N-[4-Methyl-3-(4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl)thiazol-2(3H)-ylidene]benzamide Hybrid Ring System as Potential Antibacterial Agents

Medicinal Chemistry ◽

10.2174/1573406417666210923103209 ◽

2021 ◽

Vol 17 ◽

Author(s):

Hummera Rafique ◽

Aamer Saeed ◽

Muhammad Naseem ◽

Tauqeer Riaz ◽

Fouzia Perveen ◽

...

Keyword(s):

Bacterial Resistance ◽

Antioxidant Activities ◽

Antibacterial Properties ◽

Antibacterial Activities ◽

Structural Features ◽

Ring System ◽

Biologically Active ◽

Thiazole Ring ◽

Spectroscopic Techniques ◽

Hybrid Ring

Background: Heterocyclic compounds display versatile biological applications, so the aim of this paper was to prepare biologically important heterocycles with enhanced bacterial resistance and to evaluate for their various structural features that are responsible for their biological properties. Objective: The objective was to synthesize bacterial resistance compounds with enhanced antibacterial properties. Method: Ester moiety containing thiazole ring was converted into its hydrazide derivatives. These heterocyclic derivatives were cyclized into another ring oxadiazole; hence a hybrid ring system of two biologically active rings was prepared. Result: All the synthesized compounds were characterized by spectroscopic techniques and were screened for their antibacterial potential; they possess significant antibacterial activities. Conclusion: New hybrid heterocyclic ring systems were synthesized by cyclization of hydrazide derivatives by adopting two step strategy in good yields. All the synthesized compounds were evaluated for their antioxidant activities; they showed moderate to significant activities. QSAR and Molecular docking studies were performed to determine the mode of interaction. Experimental and computational data is in accordance with the determined antibacterial activities.

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WS-5 Extract of Curcuma longa, Chaenomeles sinensis, and Zingiber officinale Contains Anti-AChE Compounds and Improves β-Amyloid-Induced Memory Impairment in Mice

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2019/5160293 ◽

2019 ◽

Vol 2019 ◽

pp. 1-16 ◽

Cited By ~ 2

Author(s):

Ju Eun Kim ◽

Abinash Chandra Shrestha ◽

Hyo Shin Kim ◽

Ha Neul Ham ◽

Jun Hyeong Kim ◽

...

Keyword(s):

Memory Impairment ◽

Antioxidant Activities ◽

Curcuma Longa ◽

Senile Plaques ◽

Total Antioxidant Status ◽

Ethanol Extract ◽

Zingiber Officinale ◽

Chaenomeles Sinensis

Alzheimer's disease (AD) is linked to an extensive neuron loss via accumulation of amyloid-beta (Aβ) as senile plaques associated with reactive astrocytes and microglial activation in the brain. The objective of this study was to assess the therapeutic effect of WS-5 ethanol extract in vitro and in vivo against Aβ-induced AD in mice and to identify the extract’s active constituents. In the present study, WS-5 exerted a significant inhibitory effect on acetylcholinesterase (AChE). Analysis by transmission electron microscopy (TEM) revealed that WS-5 prevented Aβ oligomerization via inhibition of Aβ1-42 aggregation. Evaluation of antioxidant activities using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) demonstrated that WS-5 possessed a high antioxidant activity, which was confirmed by measuring the total antioxidant status (TAS). Furthermore, the anti-inflammatory properties of WS-5 were examined using lipopolysaccharide-stimulated BV-2 microglial cells. WS-5 significantly inhibited the lipopolysaccharide–induced production of nitric oxide and two proinflammatory cytokines, TNF-α and IL-6. The memory impairment in mice with Aβ-induced AD was studied using the Morris water maze and passive avoidance test. Immunohistochemistry was performed to monitor pathological changes in the hippocampus and cortex region of the mouse brain. The animal study showed that WS-5 (250 mg/kg) treatment improved learning and suppressed memory impairment as well as reduced Aβ plaque accumulation in Aβ-induced AD. HPLC analysis identified the extract’s active compounds that exert anti-AChE activity. In summary, our findings suggest that WS-5 could be applied as a natural product therapy with a focus on neuroinflammation-related neurodegenerative disorders.

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Correlations of the physicochemical properties of organosolv lignins from Broussonetia papyrifera with their antioxidant activities

Sustainable Energy & Fuels ◽

10.1039/d0se00940g ◽

2020 ◽

Vol 4 (10) ◽

pp. 5114-5119

Author(s):

Lan Yao ◽

Long Xiong ◽

Chang Geun Yoo ◽

Chengyu Dong ◽

Xianzhi Meng ◽

...

Keyword(s):

Physicochemical Properties ◽

Antioxidant Activities ◽

Broussonetia Papyrifera ◽

Organosolv Pretreatment ◽

Different Temperatures ◽

Lignin Characteristics

To understand the influence of lignin characteristics on their antioxidant activities, lignins were isolated from Broussonetia papyrifera by organosolv pretreatment at different temperatures.

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A Novel Pectic Polysaccharide of Jujube Pomace: Structural Analysis and Intracellular Antioxidant Activities

Antioxidants ◽

10.3390/antiox9020127 ◽

2020 ◽

Vol 9 (2) ◽

pp. 127

Author(s):

Ximeng Lin ◽

Keshan Liu ◽

Sheng Yin ◽

Yimin Qin ◽

Peili Shen ◽

...

Keyword(s):

Self Assembly ◽

Antioxidant Activities ◽

Structural Features ◽

Water Retention Capacity ◽

Side Chains ◽

Sem Images ◽

Retention Capacity ◽

Pectic Polysaccharide ◽

Afm Analysis ◽

Fast Flow

After extraction from jujube pomace and purification by two columns (DEAE-Sepharose Fast Flow and Sepharcyl S-300), the structure of SAZMP4 was investigated by HPGPC, GC, FI-IR, GC-MS, NMR, SEM, and AFM. Analysis determined that SAZMP4 (Mw = 28.94 kDa) was a pectic polysaccharide mainly containing 1,4-linked GalA (93.48%) with side chains of 1,2,4-linked Rha and 1,3,5-linked Ara and terminals of 1-linked Rha and 1-linked Ara, which might be the homogalacturonan (HG) type with side chains of the RG-I type, corresponding to the results of NMR. In AFM and SEM images, self-assembly and aggregation of SAZMP4 were respectively observed indicating its structural features. The antioxidant activity of SAZMP4 against H2O2-induced oxidative stress in Caco-2 cells was determined by activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) as well as malondialdehyde (MDA) and reactive oxygen species (ROS) levels, indicating SAZMP4 can be a natural antioxidant. Also, a better water retention capacity and thermal stability of SAZMP4 was observed based on DSC analysis, which could be applied in food industry as an additive.

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