Endo-xylanase induced xylooligosaccharide production from corn cobs, its structural features, and concentration-dependent antioxidant activities

Abstract A fast, low-cost, convenient, and especially sensitive voltammetric screening approach for the study of the antioxidant properties of isoquercitrin and pedalitin from Pterogyne nitens is suggested in this work. These flavonoids were investigated for their redox properties using cyclic voltammetry in nonaqueous media using N,N-dimethylformamide and tetrabutylammonium tetrafluorborate as the supporting electrolyte, a glassy carbon working electrode, Ag|AgCl reference electrode, and Pt bare wire counter electrode. The comparative analysis of the activity of rutin has also been carried out. Moreover, combining HPLC with an electrochemical detector allowed qualitative and quantitative detection of micromolecules (e.g., isoquercitrin and pedalitin) that showed antioxidant activities. These results were then correlated to the inhibition of β-carotene bleaching determined by TLC autographic assay and to structural features of the flavonoids.

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Efficient Synthesis of Novel N-[4-Methyl-3-(4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl)thiazol-2(3H)-ylidene]benzamide Hybrid Ring System as Potential Antibacterial Agents

Medicinal Chemistry ◽

10.2174/1573406417666210923103209 ◽

2021 ◽

Vol 17 ◽

Author(s):

Hummera Rafique ◽

Aamer Saeed ◽

Muhammad Naseem ◽

Tauqeer Riaz ◽

Fouzia Perveen ◽

...

Keyword(s):

Bacterial Resistance ◽

Antioxidant Activities ◽

Antibacterial Properties ◽

Antibacterial Activities ◽

Structural Features ◽

Ring System ◽

Biologically Active ◽

Thiazole Ring ◽

Spectroscopic Techniques ◽

Hybrid Ring

Background: Heterocyclic compounds display versatile biological applications, so the aim of this paper was to prepare biologically important heterocycles with enhanced bacterial resistance and to evaluate for their various structural features that are responsible for their biological properties. Objective: The objective was to synthesize bacterial resistance compounds with enhanced antibacterial properties. Method: Ester moiety containing thiazole ring was converted into its hydrazide derivatives. These heterocyclic derivatives were cyclized into another ring oxadiazole; hence a hybrid ring system of two biologically active rings was prepared. Result: All the synthesized compounds were characterized by spectroscopic techniques and were screened for their antibacterial potential; they possess significant antibacterial activities. Conclusion: New hybrid heterocyclic ring systems were synthesized by cyclization of hydrazide derivatives by adopting two step strategy in good yields. All the synthesized compounds were evaluated for their antioxidant activities; they showed moderate to significant activities. QSAR and Molecular docking studies were performed to determine the mode of interaction. Experimental and computational data is in accordance with the determined antibacterial activities.

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A Novel Pectic Polysaccharide of Jujube Pomace: Structural Analysis and Intracellular Antioxidant Activities

Antioxidants ◽

10.3390/antiox9020127 ◽

2020 ◽

Vol 9 (2) ◽

pp. 127

Author(s):

Ximeng Lin ◽

Keshan Liu ◽

Sheng Yin ◽

Yimin Qin ◽

Peili Shen ◽

...

Keyword(s):

Self Assembly ◽

Antioxidant Activities ◽

Structural Features ◽

Water Retention Capacity ◽

Side Chains ◽

Sem Images ◽

Retention Capacity ◽

Pectic Polysaccharide ◽

Afm Analysis ◽

Fast Flow

After extraction from jujube pomace and purification by two columns (DEAE-Sepharose Fast Flow and Sepharcyl S-300), the structure of SAZMP4 was investigated by HPGPC, GC, FI-IR, GC-MS, NMR, SEM, and AFM. Analysis determined that SAZMP4 (Mw = 28.94 kDa) was a pectic polysaccharide mainly containing 1,4-linked GalA (93.48%) with side chains of 1,2,4-linked Rha and 1,3,5-linked Ara and terminals of 1-linked Rha and 1-linked Ara, which might be the homogalacturonan (HG) type with side chains of the RG-I type, corresponding to the results of NMR. In AFM and SEM images, self-assembly and aggregation of SAZMP4 were respectively observed indicating its structural features. The antioxidant activity of SAZMP4 against H2O2-induced oxidative stress in Caco-2 cells was determined by activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) as well as malondialdehyde (MDA) and reactive oxygen species (ROS) levels, indicating SAZMP4 can be a natural antioxidant. Also, a better water retention capacity and thermal stability of SAZMP4 was observed based on DSC analysis, which could be applied in food industry as an additive.

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Structural Features and Antioxidant Activities of Lignins from Steam-Exploded Bamboo (Phyllostachys pubescens)

Journal of Agricultural and Food Chemistry ◽

10.1021/jf5023093 ◽

2014 ◽

Vol 62 (25) ◽

pp. 5939-5947 ◽

Cited By ~ 24

Author(s):

Shao-Ni Sun ◽

Xue-Fei Cao ◽

Feng Xu ◽

Run-Cang Sun ◽

Gwynn Lloyd Jones

Keyword(s):

Antioxidant Activities ◽

Structural Features ◽

Phyllostachys Pubescens

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Acetic acid lignins from Chinese quince fruit (Chaenomeles sinensis): effect of pretreatment on their structural features and antioxidant activities

RSC Advances ◽

10.1039/c8ra04009e ◽

2018 ◽

Vol 8 (44) ◽

pp. 24923-24931 ◽

Cited By ~ 8

Author(s):

Zhao Qin ◽

Zhao-Guo Zhang ◽

Hua-Min Liu ◽

Guang-Yong Qin ◽

Xue-De Wang

Keyword(s):

Acetic Acid ◽

Antioxidant Activities ◽

Structural Features ◽

Lignin Extraction ◽

Chaenomeles Sinensis ◽

Multiple Processes ◽

Chinese Quince

Three pretreatments, including sugar removal, dephenolization and multiple processes, are applied on the lignin extraction from Chinese quince fruits.

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Structural features, chemical composition, antioxidant activities of organosolv lignins extracted from black and white sesame capsules and stalks

Industrial Crops and Products ◽

10.1016/j.indcrop.2021.113677 ◽

2021 ◽

Vol 169 ◽

pp. 113677

Author(s):

Zhao Qin ◽

Qiao-Li Yang ◽

Xi-Chuang Cheng ◽

Hua-Min Liu ◽

Xue-De Wang

Keyword(s):

Chemical Composition ◽

Antioxidant Activities ◽

Structural Features ◽

Black And White

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Antioxidant Evaluation and Chemo-Profiling of Non-conventional Curcuma Species as Conservation of Drug Targeting Molecule

10.21203/rs.3.rs-20453/v1 ◽

2020 ◽

Author(s):

Akanksha Jain ◽

Parag Jain

Keyword(s):

Antioxidant Activities ◽

Radical Scavenging Activity ◽

Curcuma Longa ◽

Group Analysis ◽

Radical Scavenging ◽

Reducing Power ◽

Structural Features ◽

Total Phenolic ◽

Significant Difference

Abstract The objective of the present study was to determine and compare antioxidant activities of different species of Curcuma i.e. Curcuma longa, Curcuma caesia and Curcuma aromatic and their chemoprofiling for conservation of highest yield plants. The functional group analysis of the plants extract were determined by FTIR and structural features of phyto-constituents and Chemo-profiling of ethanol fractions of all targeted Curcuma species showing highest activity were analyzed by GC–MS/MS. Ethanolic extract of C. aromatica (ECA) was exhibited to determine high radical scavenging activity against DPPH (92.12%), lipid Peroxidation (85.13 ± 0.23%), nitric oxide scavenging, total reducing power (700.83 ± 8.14 μg/mg) and ferric reducing power assay. In ABTS·+ and phosphomolybdate assay Curcuma species showed a significant difference ranging from 67.53 – 98.57%. Furthermore, the amount of total phenolic and flavonoid content ranged from 3.63± 1.06 – 545.77 ± 2.76 μg/mg eq GAE and 21.18 –101.29 μg/mg eq QUE respectively. The results indicated that the ethanolic extracts showed highest in vitro antioxidant activity. It can be conclude from the study that Curcuma species may serve as an important bioresource as an antioxidant drug.

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Structural Features, Antitumor and Antioxidant Activities of Rice Bran Polysaccharides Using Different Extraction Methods

Journal of Food Science ◽

10.1111/1750-3841.13776 ◽

2017 ◽

Vol 82 (10) ◽

pp. 2403-2410 ◽

Cited By ~ 2

Author(s):

Wenfang Han ◽

Jiangtao Li ◽

Yuqin Ding ◽

Shanbai Xiong ◽

Siming Zhao

Keyword(s):

Rice Bran ◽

Antioxidant Activities ◽

Extraction Methods ◽

Structural Features

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ASSESSMENT OF ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF A SPECIES OF ASPERGILLUS: AN ENDOPHYTIC FUNGUS OF SCHIMA WALLICHII (DC.) KORTH. LEAVES

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10i9.19501 ◽

2017 ◽

Vol 10 (9) ◽

pp. 361

Author(s):

Sunrit Basu Sarbadhikary ◽

Narayan Chandra Mandal

Keyword(s):

Antioxidant Activity ◽

Ethyl Acetate ◽

Mode Of Action ◽

Pathogenic Bacteria ◽

Ethyl Acetate Extract ◽

Antioxidant Activities ◽

Pathogenic Fungi ◽

Structural Features ◽

Fungal Endophyte ◽

Schima Wallichii

Objective: The main goals of this study were to check the antimicrobial and antioxidant potentials of an endophytic fungal strain isolated from the leaves of Schima wallichii (DC.) Korth.Methods: The antibacterial and antifungal activities of the isolated fungal endophyte Visva-Bharati endophyte fungal (VBEF2) were checked by disc diffusion and agar well diffusion methods, respectively, against six pathogenic bacteria and four pathogenic fungi. The minimum inhibitory concentration (MIC) values and the mode of action of VBEF2 against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli were determined following colony-forming units (CFU) counting method. Antioxidant activity of the isolate was studied following 2, 2-diphenyl-2- picrilhydrazyl (DPPH) reduction assay.Results: The cell-free supernatants (CFS) of VBEF2 exhibited excellent antibacterial activity against all the bacteria used. The ethyl acetate extract of the endophyte was found to have the MIC of 50 μg/ml and 150 μg/ml against S. aureus and E. coli, respectively. It showed bactericidal mode of action against both of them. The CFS of the strain VBEF2 also showed excellent activities against two animal and two plant pathogenic fungi by producing zones of inhibition in the range of 10-20 mm. In the DPPH scavenging antioxidant assay, the ethyl acetate extract of VBEF2 was found with a low IC50 value of 19.01 μg/ml. The strain VBEF2 was identified as a species of Aspergillus based on its colony morphology and structural features observed under a compound light microscope.Conclusion: The strain VBEF2 can be implemented in various fields of pharmaceutical industry as it showed multidimensional beneficial attributes such as excellent antimicrobial and antioxidant activity.

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