scholarly journals Metabolic profiling of human blood by high-resolution ion mobility mass spectrometry (IM-MS)

2010 ◽  
Vol 298 (1-3) ◽  
pp. 78-90 ◽  
Author(s):  
Prabha Dwivedi ◽  
Albert J. Schultz ◽  
Herbert H. Hill Jr
Keyword(s):  
Mass Spectrometry ◽  
High Resolution ◽  
Human Blood ◽  
Ion Mobility ◽  
Metabolic Profiling ◽  
Ion Mobility Mass Spectrometry

scholarly journals Metabolic profiling of Escherichia coli by ion mobility-mass spectrometry with MALDI ion source

2010 ◽  
Vol 45 (12) ◽  
pp. 1383-1393 ◽  
Author(s):  
Prabha Dwivedi ◽  
Geoffery Puzon ◽  
Maggie Tam ◽  
Denis Langlais ◽  
Shelley Jackson ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Escherichia Coli ◽  
Ion Mobility ◽  
Metabolic Profiling ◽  
Ion Source ◽  
Ion Mobility Mass Spectrometry

High resolution ion mobility-mass spectrometry for separation and identification of isomeric lipids

The Analyst ◽  
2015 ◽  
Vol 140 (20) ◽  
pp. 6904-6911 ◽  
Author(s):  
M. Groessl ◽  
S. Graf ◽  
R. Knochenmuss
Keyword(s):  
Mass Spectrometry ◽  
Double Bond ◽  
High Resolution ◽  
Ion Mobility ◽  
Biological Samples ◽  
Drift Tube ◽  
Acyl Chain ◽  
Ion Mobility Mass Spectrometry

Separation and identification of isomeric species is a major challenge in lipidomics. Herein, we demonstrate that lipid isomers that differ only in position of the acyl chain, position of the double bond or double bond geometry can be distinguished using drift-tube ion mobility-mass spectrometry, even in complex biological samples.

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