scholarly journals Traditional Chinese medicine attenuates hospitalization and mortality risks in diabetic patients with carcinoma in situ in Taiwan

2021 ◽  
pp. 100831
Author(s):  
Li-Jen Tsai ◽  
Chi-Hsiang Chung ◽  
Chien-Jung Lin ◽  
Sheng-Chiang Su ◽  
Feng-Chih Kuo ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Carcinoma In Situ ◽  
Diabetic Patients ◽  
Mortality Risks

scholarly journals Metformin Attenuates Osteoporosis in Diabetic Patients with Carcinoma in Situ: A Nationwide, Retrospective, Matched-Cohort Study in Taiwan

2020 ◽  
Vol 9 (9) ◽  
pp. 2839 ◽  
Author(s):  
Chieh-Hua Lu ◽  
Chi-Hsiang Chung ◽  
Feng-Chih Kuo ◽  
Kuan-Chan Chen ◽  
Chia-Hao Chang ◽  
...  
Keyword(s):  
Carcinoma In Situ ◽  
Diabetic Patients ◽  
Research Database ◽  
Proportional Hazard ◽  
Metformin Therapy ◽  
Cox Proportional Hazard ◽  
Metformin Group ◽  
Patients With Diabetes

Patients with diabetes are at increased risk of cancer development and osteoporosis. Metformin is an effective agent for diabetes management. Epidemiological studies have identified an association between metformin use and cancer prevention. This article outlines the potential for metformin to attenuate the rate of osteoporosis in diabetic patients with carcinoma in situ (CIS). From the National Health Insurance Research Database of Taiwan, 7827 patients with diabetes with CIS who were receiving metformin therapy were selected, along with 23,481 patients as 1:3 sex-, age- and index year-matched controls, who were not receiving metformin therapy. A Cox proportional hazard analysis was used to compare the rate of osteoporosis during an average of 15-year follow-up. Of the subjects who were enrolled, 801 (2.56%) had osteoporosis, including 168 from the metformin group (2.15%) and 633 from the without metformin group (2.70%). The metformin group presented a lower rate of osteoporosis at the end of follow-up (p = 0.009). The Cox proportional hazard regression analysis revealed a lower rate of osteoporosis for the metformin group (adjusted hazard ratio of 0.820; 95% confidence interval = 0.691–0.972, p = 0.022). Diabetic patients with CIS under metformin therapy presented lower osteoporosis rate than those who were not receiving metformin therapy.

scholarly journals Review of Herbal Traditional Chinese Medicine for the Treatment of Diabetic Nephropathy

2016 ◽  
Vol 2016 ◽  
pp. 1-18 ◽  
Author(s):  
Guang-dong Sun ◽  
Chao-yuan Li ◽  
Wen-peng Cui ◽  
Qiao-yan Guo ◽  
Chang-qing Dong ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Diabetic Patients ◽  
Protective Effects ◽  
Chronic Complications ◽  
Poor Treatment ◽  
Stage Renal Disease ◽  
End Stage ◽  
And Control

Diabetic nephropathy (DN) is the most serious chronic complications of diabetes; 20–40% of diabetic patients develop into end stage renal disease (ESRD). However, exact pathogenesis of DN is not fully clear and we have great difficulties in curing DN; poor treatment of DN led to high chances of mortality worldwide. A lot of western medicines such as ACEI and ARB have been demonstrated to protect renal function of DN but are not enough to delay or retard the progression of DN; therefore, exploring exact and feasible drug is current research hotspot in medicine. Traditional Chinese medicine (TCM) has been widely used to treat and control diabetes and its complications such as DN in a lot of scientific researches, which will give insights into the mechanism of DN, but they are not enough to reveal all the details. In this paper, we summarize the applications of herbal TCM preparations, single herbal TCM, and/or monomers from herbal TCM in the treatment of DN in the recent 10 years, depicting the renal protective effects and the corresponding mechanism, through which we shed light on the renal protective roles of TCM in DN with a particular focus on the molecular basis of the effect and provide a beneficial supplement to the drug therapy for DN.

scholarly journals What Is the Relationship between Diabetic Patients and Greater Propensity to COVID-19?

2021 ◽  
Vol 6 (1) ◽  
Keyword(s):  
Systematic Review ◽  
Case Report ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Current Evidence ◽  
Diabetic Patients ◽  
Energy Deficiency ◽  
Yin Deficiency ◽  
Patients With Diabetes ◽  
The Relationship

Patients with diabetes are more likely to have COVID-19 as demonstrated in the article written by Abdi et al. (2020) entitled Diabetes and COVID-19: A systematic review on the current evidence [1]. But what is the real reason why diabetic patients being more likely to have COVID-19 than the hyperglycemia they present? In the article written by the author (2019) Why Are Diabetic Patients Still Having Hyperglycemia despite Diet Regulation, Antiglycemic Medication and Insulin? the author demonstrates through a case report, that diabetic patients have chakras’ energy deficiency, that is leading to alteration in the energy level, leading to Yin deficiency and Heat retention, that are two energy imbalances that is producing hyperglycemia according to traditional Chinese Medicine, in the root level of the tree [1, 2].

Screening of Chemical Dyes in Traditional Chinese Medicine by HPTLC-MS

2018 ◽  
Vol 101 (3) ◽  
pp. 686-694 ◽  
Author(s):  
Fengyan He ◽  
Yi He ◽  
Xiaowei Zheng ◽  
Ruizhong Wang ◽  
Jing Lu ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Raw Materials ◽  
Orange Ii ◽  
Sudan I ◽  
Tlc Plates ◽  
Chinese Patent ◽  
Rf Values ◽  
Cover Up

Abstract It has been uncovered that chemical dyes are illegally used in traditional Chinese medicines to brighten color and cover up inferiority, which threaten the safety of patients. In the present study, an HPTLC-MS method was developed for the effective screening of 11 chemical dyes (Sudan I, II, III, and IV; 808 Scarlet; Sudan Red 7B; malachite green; Basic Orange 2; auramine; Orange II; and erythrosine) in traditional Chinese medicine (TCM) raw materials and Chinese patent medicines. Firstly, unwashed HPTLC plates were chosen by comparing the background signals of the TLC plates used directly and prewashed with analytical grade and HPLC grade solvents. Twice developments were conducted to isolate chemical dyes of different polarity. Possible adulterants were preliminarily identified by comparing Rf values and in situ UV-Vis spectra with those of the references. Further confirmation was conducted by tandem MS analysis via an elution head-based TLC-MS interface. Sudan I and IV, 808 Scarlet, and Orange II were successfully detected in eight batches of TCM. The proposed method could be applied as a reliable technology for the screening of chemical dyes in TCM.

scholarly journals Chinese Medicine Formula “Jian-Pi-Zhi-Dong Decoction” Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Dao-han Wang ◽  
Wei Li ◽  
Xiao-fang Liu ◽  
Jin-ming Zhang ◽  
Su-mei Wang
Keyword(s):  
In Situ Hybridization ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Dopamine Transporter ◽  
Tourette Syndrome ◽  
Stereotyped Behavior ◽  
Mice Model ◽  
Chinese Medicine Formula ◽  
Abnormal Behaviors

Jian-Pi-Zhi-Dong Decoction (JPZDD) is dedicated to the treatment for Tourette syndrome (TS) with the guidance of the theories of Traditional Chinese Medicine (TCM). This study aims to investigate the expression of dopamine transporter (DAT) in the striatum and stereotyped behavior of TS mice model by intervention of JPZDD. Mice were induced by 3,3′-iminodipropionitrile (IDPN, 350 mg kg−1day−1, i.p.) for 7 days and divided into 4 groups (n=20, each): control and IDPN groups were gavaged with saline and the remaining 2 groups with Tiapride (Tia, 50 mg kg−1day−1) and JPZDD (20 g kg−1day−1), respectively. The results showed that the scores of stereotyped behavior in IDPN+JPZDD group were significantly reduced. A noticeably increased11C-β-CFT binding at bilateral striatum was observed after administration of JPZDD versus that of IDPN or Tia. Immunohistochemistry and in situ hybridization studies manifested higher levels of DAT protein and mRNA in IDPN+JPZDD group. These findings not only demonstrated that JPZDD could effectively inhibit the abnormal behaviors of TS mice model, but also increase the level of DAT in striatum. Therefore, JPZDD could be one of potential treatments of patients with TS.

Improving insulin resistance with traditional Chinese medicine in type 2 diabetic patients

Endocrine ◽  
2009 ◽  
Vol 36 (2) ◽  
pp. 268-274 ◽  
Author(s):  
Menglei Chao ◽  
Dajin Zou ◽  
Yifei Zhang ◽  
Yuhong Chen ◽  
Miao Wang ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

scholarly journals THE SCOPING REVIEW OF CHINESE AND WESTERN MEDICINE TREATMENT OF DIABETIC FOOT IN ASIA

2020 ◽  
Author(s):  
Wang Xinyan ◽  
Wang Yinuo ◽  
Yu Hanyi ◽  
Muhammad Shahzad Aslam
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Peer Review ◽  
Scoping Review ◽  
Diabetic Foot ◽  
Western Medicine ◽  
Foot Ulcers ◽  
Diabetic Patients ◽  
E Mail

Diabetic foot is a common and serious chronic complication of diabetes due to the simultaneous occurrence of diabetic peripheral neuropathy and vascular lesion. Among all complications, foot ulcers in diabetic ulcers account for the first place among the reasons for hospitalization and treatment of diabetic patients. 15% of diabetic patients may have foot diseases, and 85% of patients may have foot ulcers as the cause of amputation. Diabetic foot seriously affects the quality of life of patients. Although there are many methods to treat diabetic foot, the therapeutic effect of diabetic foot is not ideal in general. The main purpose of this scoping review was analyzing the existing loopholes of researches on diabetic foot in Asia. Used Pub Med, CNKI, Wangfang data, CQVIP to search and select 5 traditional Chinese medicine literatures and 5 western medicine literature, through the comparison of various conditions between literature to analyze the lack of research. Ten pieces of literature were retained through 183 records and included 9 drugs or decoction, they were adipose-derived stem cell–hydrogel complex, hyperbaric oxygen therapy, Xenogeneic (porcine) a cellular dermal matrix, alprostadil, salvia miltiorrhiza polyphenols for injection and collagen sponge, Taohong Siwu Decoction, Simiao Yong an Decoction, Jiawei Simiao Yong an Decoction, Huangqi Guizhi Wuwu Tang, and Wuwei Xiaodu Drink. The obvious problems found by this scoping review were the quantity and quality deficiency of the research in the diabetic foot in Asia. Scoping review is an effective method of evidence identification and synthesis, which can provide a basis for the further development of a certain field. In the further study of the diabetic foot, more attention should be paid to the verification of experimental data as well as the feasibility of the researches on oral drugs. Peer Review History: Received 6 March 2019; Revised 22 April; Accepted 4 May, Available online 15 May 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Name: Dr. Sabah Hussien El-Ghaiesh Affiliation: Tanta University, Egypt E-mail: [email protected]   Name: Dr. Mohamed Derbali Affiliation: Faculty of Pharmacy, Monastir, Tunisia E-mail: [email protected] Comments of reviewer(s): Similar Articles: HOW DO VITAMIN AND PLANT SEEDS WORK AS HYPOLIPIDEMIC AGENTS ? TRADITIONAL CHINESE MEDICINE ENDOTHERAPY OF DIABETIC WOUNDS: A SCOPING REVIEW

scholarly journals Why Are Diabetic Patients Still Having Hyperglycemia despite Diet Regulation, Antiglycemic Medication and Insulin?

2019 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Western Medicine ◽  
Eating Habits ◽  
Point Of View ◽  
Diabetic Patients ◽  
Treatment Goals ◽  
Diabetes Treatment ◽  
Holistic View

Introduction: Diabetes and its complications were responsible for 8.8% of deaths worldwide in 2017. Although Western Medicine and Traditional Chinese Medicine (TCM) share the diabetes treatment goals of reducing symptoms and preventing complications, their approaches to conceptualizing, diagnosing, and treating the disease are very different. Purpose: The aim of this study is to demonstrate the different gaps in the Western Medicine treatment for diabetes that can be explained by Traditional Chinese Medicine, from an energy imbalance point of view. Methods: Through a case report of a 26-year-old male patient diagnosed with Type 2 diabetes in 2016, the author analyzes two approaches, Western and Traditional Chinese Medicine. The patient’s received analysis of all their: • eating habits, • use of high-concentrated medications, • use of microwave ovens, • quantity and temperature of water intake, and • Quantity of sleep. All these items were analyzed according to Traditional Chinese Medicine. Despite treatment with diet along with the use of antiglycemic medications and insulin, the patient’s glycemia was still high. Use of the Western Medicine approach achieved a 750 mg/dl reading after 2 years (in September 2018). Results: In January 2019, a month and a half after the beginning of the treatment with Traditional Chinese Medicine, the patient's glycemia dropped to 150 to 250 mg/dl. Conclusion: A more holistic view of the human body has major importance. A deeper comprehension of the energy’s behavior, including its relation to pathologies, creates different possibilities of treatment. The suspension of sugar and high-carbohydrate foods in the diabetic patient’s diet is not sufficient to control the patient glycemia alone. Still the use of high-concentrated medications can be a factor to maintain the hyperglycemic state. This shows that the integration of Western Medicine and Traditional Chinese Medicine is important to better control the glycemia in diabetes patients.

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