42.10 FAMILY AND PEER ENVIRONMENTAL FACTORS AND PERSONAL ATTITUDES TOWARD SMOKING PREDICT EPIGENETIC POSITIVITY FOR SMOKE EXPOSURE IN A MIDDLE ADOLESCENT LONGITUDINAL COHORT

Abstract The majority of today’s adult smokers took up the habit during adolescence. The school community and the rules it imposes are important factors that can influence adolescents’ smoking intention and behaviour. Research on the effect of school tobacco policies on adolescents’ smoking concludes with mixed results. Our study aims to look at the influence of these policies on the intention to smoke and to know if this relation is mediated by individual and environmental factors. The study includes information on social norms, attitude towards smoking and smoking intention from 4515 students of 32 Ticino middle schools and on the tobacco policy implemented in this school. Linear regression indicates a marginal impact of school policy on intention to smoke. Schools that strongly enforce tobacco policy obtain an increase in their students’ intention to smoke, while schools that implement assistance programmes to overcome tobacco use decrease intention to smoke. Mediation models show that the influence of some of tobacco policy dimensions on the intention to smoke is mediated by personal attitudes towards smoking, beliefs about health consequences of smoking and perceived peers smoking. Increasing visibility of tobacco policies and having tobacco prevention programmes have stronger positive effects on smoking intention than other policy dimensions, but only through the mediation of individual and environmental factors.

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Exposure to Cigarette Smoke Enhances Pneumococcal Transmission Among Littermates in an Infant Mouse Model

Frontiers in Cellular and Infection Microbiology ◽

10.3389/fcimb.2021.651495 ◽

2021 ◽

Vol 11 ◽

Author(s):

Daichi Murakami ◽

Masamitsu Kono ◽

Denisa Nanushaj ◽

Fumie Kaneko ◽

Tonia Zangari ◽

...

Keyword(s):

Environmental Factors ◽

Mouse Model ◽

Cigarette Smoke ◽

Close Contact ◽

Smoke Exposure ◽

Mucosal Barrier ◽

Cigarette Smoke Exposure ◽

New Host ◽

Infant Mouse ◽

The Impact

Streptococcus pneumoniae, one of the most common commensal pathogens among children, is spread by close contact in daycare centers or within a family. Host innate immune responses and bacterial virulence factors promote pneumococcal transmission. However, investigations into the effects of environmental factors on transmission have been limited. Passive smoking, a great concern for children’s health, has been reported to exacerbate pneumococcal diseases. Here, we describe the effect of cigarette smoke exposure on an infant mouse model of pneumococcal transmission. Our findings reveal that the effect of cigarette smoke exposure significantly promotes pneumococcal transmission by enhancing bacterial shedding from the colonized host and by increasing susceptibility to pneumococcal colonization in the new host, both of which are critical steps of transmission. Local inflammation, followed by mucosal changes (such as mucus hypersecretion and disruption of the mucosal barrier), are important underlying mechanisms for promotion of transmission by smoke exposure. These effects were attributable to the constituents of cigarette smoke rather than smoke itself. These findings provide the first experimental evidence of the impact of environmental factors on pneumococcal transmission and the mechanism of pathogenesis.

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Reductionist thinking and animal models in neuropsychiatric research

Behavioral and Brain Sciences ◽

10.1017/s0140525x18001231 ◽

2019 ◽

Vol 42 ◽

Cited By ~ 1

Author(s):

Nicole M. Baran

Keyword(s):

Animal Models ◽

Mental Disorders ◽

Environmental Factors ◽

Neuropsychiatric Disorders ◽

Model Organisms ◽

Developmental Genetic ◽

Term Study ◽

Genetic And Environmental Factors ◽

Mechanisms Of Plasticity

AbstractReductionist thinking in neuroscience is manifest in the widespread use of animal models of neuropsychiatric disorders. Broader investigations of diverse behaviors in non-model organisms and longer-term study of the mechanisms of plasticity will yield fundamental insights into the neurobiological, developmental, genetic, and environmental factors contributing to the “massively multifactorial system networks” which go awry in mental disorders.

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Dental students' attitudes toward smoking cessation guidelines

Journal of Dental Education ◽

10.1002/j.0022-0337.2000.64.9.tb03370.x ◽

2000 ◽

Vol 64 (9) ◽

pp. 641-650 ◽

Cited By ~ 18

Author(s):

JK Yip ◽

JL Hay ◽

JS Ostroff ◽

RK Stewart ◽

GD Cruz

Keyword(s):

Smoking Cessation ◽

Dental Students ◽

Students Attitudes ◽

Attitudes Toward Smoking

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The dual nature of obesity in metabolic programming: quantity versus quality of adipose tissue

Clinical Science ◽

10.1042/cs20201028 ◽

2020 ◽

Vol 134 (18) ◽

pp. 2447-2451

Author(s):

Anissa Viveiros ◽

Gavin Y. Oudit

Keyword(s):

Adipose Tissue ◽

Environmental Factors ◽

Maternal Obesity ◽

Metabolic Programming ◽

Dual Nature ◽

Prevalence Of Obesity ◽

Adipose Tissue Volume ◽

Males And Females ◽

Metabolically Healthy

Abstract The global prevalence of obesity has been rising at an alarming rate, accompanied by an increase in both childhood and maternal obesity. The concept of metabolic programming is highly topical, and in this context, describes a predisposition of offspring of obese mothers to the development of obesity independent of environmental factors. Research published in this issue of Clinical Science conducted by Litzenburger and colleagues (Clin. Sci. (Lond.) (2020) 134, 921–939) have identified sex-dependent differences in metabolic programming and identify putative signaling pathways involved in the differential phenotype of adipose tissue between males and females. Delineating the distinction between metabolically healthy and unhealthy obesity is a topic of emerging interest, and the precise nature of adipocytes are key to pathogenesis, independent of adipose tissue volume.

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Shared Responsibilities for Full Participation in Society: Planning Further Integration of the ICF Into AAC

Perspectives of the ASHA Special Interest Groups ◽

10.1044/persp1.sig12.83 ◽

2016 ◽

Vol 1 (12) ◽

pp. 83-93 ◽

Cited By ~ 1

Author(s):

Mary Blake Huer ◽

Travis T. Threats

Keyword(s):

Environmental Factors ◽

Augmentative And Alternative Communication ◽

Functional Limitations ◽

Community Support ◽

World Health ◽

International Classification Of Functioning ◽

Personal Factors ◽

Social Service Agencies ◽

Persons With Disabilities ◽

Full Participation

The World Health Organization's (WHO's) 2001 International Classification of Functioning Disability and Health (ICF) has as one of its central tenets the full inclusion of persons with disabilities in society. It acknowledges the need for medical and rehabilitation intervention in its biopscychosocial framework. However, the WHO realizes that society must do its part to facilitate this full participation and empowerment. Persons with complex communication needs (PWCCN) often need augmentative and alternative communication (AAC) in order to express themselves. However, in order to access and successfully use AAC, PWCCN need access to the necessary AAC devices and services, as well as a willing society to interact with them as full contributing members of society. The factors outside of a person's specific physical and/or cognitive functional limitations are addressed in the ICF via the Personal and Environmental Factors. Personal Factors include the individual's personality traits, lifestyle, experiences, social/educational/professional background, race, gender, and age. Environmental Factors include community support systems, social service agencies, governments, social networks, and those persons that interact with the PWCCN. This article addresses the sociopolitical influences on PWCCN and their functioning from a human rights perspective. The necessary introspective role of speech-language pathologists in this process is explored.

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