scholarly journals Blood Cadmium and C-Reactive Protein Levels As Risk Factors for Allergic and Respiratory Diseases in Early Childhood: The Mothers and Children's Environmental Health Study

2017 ◽  
Vol 139 (2) ◽  
pp. AB203
Author(s):  
Ja Hyeong Kim ◽  
Eun-Hee Ha ◽  
Hyesook Park ◽  
Mina Ha ◽  
Yun-Chul Hong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Early Childhood ◽  
Environmental Health ◽  
Respiratory Diseases ◽  
Health Study ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Blood Cadmium ◽  
Children’S Environmental Health

Abstract P096: Maternal Serum C-Reactive Protein Levels During Pregnancy and Risk for High C-Reactive Protein 7-13 Years Later

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Bonny Rockette-Wagner ◽  
Claudia Holzman ◽  
Bertha L Bullen ◽  
Andrew D Althouse ◽  
Janet M Catov
Keyword(s):  
Relative Risk ◽  
Weight Change ◽  
Elevated Serum ◽  
Maternal Serum ◽  
Health Study ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Inflammatory Status

Introduction: Elevated serum C-reactive protein (CRP) can be a marker of disease activity involving inflammation, such as pregnancy complications and cardiovascular disease (CVD). Systemically high levels of CRP in women, including during pregnancy, may indicate higher risk for CVD. It is unknown if CRP measured during the pro-inflammatory state of pregnancy correlates with concentrations assessed 7-13 years after delivery. Hypothesis: Concentrations of CRP assessed during pregnancy will be related to CRP measured several years after pregnancy, independent of weight gain. Methods: We studied the first 252 women enrolled in the follow-up of the Pregnancy Outcomes and Community Health Study (POUCHmoms 2011-2013) with complete CRP data for the pregnancy (mean gestational age: 22.36 [2.22] weeks) and POUCHmoms visits (mean follow-up: 10.76 [1.38] years). The relative risk for high hsCRP (≥ 3.39 μg/ml) at the follow-up visit, related to quartiles of CRP during pregnancy, was examined using stepwise regression models. Results: Median (IQR) levels of pregnancy CRP and hsCRP at the follow-up visit were 5.68 [3.08, 9.76] and 3.39 [0.69, 9.73] μg/ml, respectively. Although absolute values of hsCRP at follow-up were generally lower than pregnancy CRP, 56% of women in the top and bottom quartiles of pregnancy CRP (71 of 126) were in the same quartile for hsCRP at follow-up (figure). The relative risk of having high hsCRP (≥ 3.39 μg/ml) at follow-up ranged from 2.7-5.2 for the 2 nd - 4 th quartiles of pregnancy CRP (vs. the 1st quartile). Controlling for pre-pregnancy BMI and follow-up weight change, the relative risk of having high hsCRP at follow-up was significantly higher for the 2 nd (1.15 [1.02-1.30]),3 rd (1.19 [1.05-1.35), and 4 th (1.22 [1.05-1.41]) quartiles of pregnancy CRP. Conclusions: Pregnancy CRP levels are related to hsCRP levels several years later in this cohort of women, even after adjusting for pre-pregnancy BMI and follow-up weight change. CRP assessed in pregnancy may reflect inflammatory status later in life.

Association between diet, lifestyle, metabolic cardiovascular risk factors, and plasma C-reactive protein levels

Metabolism ◽  
2004 ◽  
Vol 53 (11) ◽  
pp. 1436-1442 ◽  
Author(s):  
Gunilla Nordin Fredrikson ◽  
Bo Hedblad ◽  
Jan-Åke Nilsson ◽  
Ragnar Alm ◽  
Göran Berglund ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

scholarly journals Joint evaluation of serum C-Reactive Protein levels and polygenic risk scores as risk factors for schizophrenia

2018 ◽  
Vol 261 ◽  
pp. 148-153 ◽  
Author(s):  
Vishwajit L. Nimgaonkar ◽  
Faith Dickerson ◽  
Jennie G. Pouget ◽  
Kodavali Chowdari ◽  
Colm O’Dushlaine ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Scores ◽  
C Reactive Protein ◽  
Polygenic Risk ◽  
Protein Levels ◽  
Reactive Protein ◽  
Joint Evaluation

scholarly journals SERUM ZINC AND C-REACTIVE PROTEIN LEVELS AS RISK FACTORS FOR MORTALITY IN SYSTEMIC INFLAMMATORY RESPONSE SYNDROME

2018 ◽  
Vol 24 (1) ◽  
pp. 1
Author(s):  
Dwi Retnoningrum ◽  
Banundari Rachmawati ◽  
Dian Widyaningrum
Keyword(s):  
Risk Factors ◽  
Systemic Inflammatory Response Syndrome ◽  
Inflammatory Response ◽  
Serum Zinc ◽  
Latex Agglutination ◽  
Systemic Inflammatory Response ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

Kondisi Systemic Inflammatory Response Syndrome (SIRS) berkebahyaan terjadinya sepsis dan kegagalan multi organ. Inflamasidapat menyebabkan terjadinya redistribusi zinc ke jaringan sehingga terjadi penurunan kadar zinc plasma. Kadar CRP pada SIRSmeningkat sebagai respons peningkatan protein tahap akut. Tujuan penelitian ini untuk mengetahui apakah kadar zinc dan CRP serummerupakan faktor kebahayaan kematian di pasien SIRS. Penelitian observasional analitik dengan pendekatan kohort prospektif di 30pasien SIRS berusia 27–64 tahun. Kadar zinc serum diperiksa dengan metode atomic absorbance spectrophotometer (AAS) dan CRPserum dengan metode latex agglutination immunoassay menggunakan alat autoanaliser. Kejadian kematian subjek dinilai setelah 28hari perawatan. Data dilakukan uji statistik Chi-Kwadrat, bila tidak memenuhi maka dilakukan uji alternatif Fisher. Besarnya nilaifaktor kebahyaan dilakukan perhitungan kebahayaan relatif. Rerata kadar zinc dan CRP berturut-turut 81,24 ± 8,72 μg/dL, dan 8,13± 8,12 mg/dL. Kematian dalam 28 hari adalah 33,3%. Penelitian ini menunjukkan bahwa kadar zinc plasma < 80 μg/dL bukanmerupakan faktor kebahayaan terjadinya kematian (p=0,114), sedangkan kadar CRP ≥ 10 mg/dL merupakan faktor kebahayaanterjadinya kematian di pasien SIRS (RR=3,28, 95% CI 1,33-8,13, p=0,015). Kadar zinc plasma bukan merupakan faktor kebahayaanterjadinya kematian pada SIRS, sedangkan kadar CRP merupakan faktor kebahayaan terjadinya kematian di pasien SIRS.

L 028 COMPARISON AMONG SUBCLINICAL ATHEROSCLEROSIS, C-REACTIVE PROTEIN LEVELS AND CLASSICAL RISK FACTORS IN OBESE AND NON OBESE CHILDREN IN CHILE

2007 ◽  
Vol 8 (3) ◽  
pp. 24
Author(s):  
Pilar Arnaiz Gomez ◽  
Mónica Acevedo Blanco ◽  
Salesa Barja Yañez ◽  
Beatriz Guzman Alvarado ◽  
Jacqueline Carvajal Torrealba ◽  
...  
Keyword(s):  
Risk Factors ◽  
Subclinical Atherosclerosis ◽  
Obese Children ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

Serum C-reactive protein levels and body mass index in children and adolescents with CHD

2016 ◽  
Vol 27 (6) ◽  
pp. 1083-1089 ◽  
Author(s):  
Maíra Ribas Goulart ◽  
Daniela Schneid Schuh ◽  
David W. Moraes ◽  
Sandra Mari Barbiero ◽  
Lucia Campos Pellanda
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Children And Adolescents ◽  
Body Mass ◽  
Heart Defects ◽  
Body Mass Index Percentile ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Significant Difference

AbstractBackgroundThe prevalence of overweight in children with CHD is about 26.9%. Increase in adipose tissue is related to the secretion of proinflammatory markers such as C-reactive protein. Assuming that children with CHD are exposed to other inherent risk factors for heart disease, our objective was to evaluate the correlation between levels of C-reactive protein and body mass index in children and adolescents with CHD.MethodsA cross-sectional study with 377 children and adolescents with CHD in a clinical setting of a reference hospital was carried out. C-reactive protein data were collected after 12 hours of fasting. Nutritional status was classified according to body mass index. The patients were divided into three groups: cyanotic, acyanotic, and minimal heart defects (controls).ResultsThe mean age was 9.9±4.2 years, and 53.6% of the sample included males. The cyanotic group represented 22.3%, acyanotic 42.2%, and minimal defects 35.5% of the sample. The average body mass index percentile was 57.23±32.06. The median values of C-reactive protein were as follows: cyanotic 0.340, acyanotic with clinical repercussion 0.203, and minimal defects 0.128. There was a significant difference between the minimal defects and the cyanotic groups (p=0.023). There was a significant correlation between C-reactive protein and body mass index percentile (r=0.293, p<0.01). C-reactive protein levels were higher in girls (p=0.034). There were no significant correlations between C-reactive protein and age or birth weight.ConclusionThe correlation between body mass index percentile and C-reactive protein was confirmed in this population. The prevention of overweight is paramount to avoid overlapping modifiable risk factors to those already inherent to the CHD.

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