scholarly journals Effects of two formulations containing Phyllanthus emblica and Tinospora cordifolia with and without Ocimum sanctum in immunocompromised mice

2021 ◽  
Author(s):  
Harshad Malve ◽  
Dipti More ◽  
Ashwini More
Keyword(s):  
Tinospora Cordifolia ◽  
Ocimum Sanctum ◽  
Phyllanthus Emblica ◽  
Immunocompromised Mice

Antiviral and Immunity-modulating Natural Herbs in the Prevention of COVID-19

2021 ◽  
pp. 81-94
Author(s):  
Sonali S Gadge
Keyword(s):  
Immune System ◽  
Medicinal Plants ◽  
Nigella Sativa ◽  
Curcuma Longa ◽  
Antiviral Drug ◽  
Herbal Medicines ◽  
Echinacea Purpurea ◽  
Black Pepper ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum

The COVID-19 has spread all over the world and there is no single drug or medicine for the prevention and the treatment of this deadly disease. One can get prevention from this disease by boosting the immune system. Persons with weak immune system e.g. children, elder patients or patients with preexisting diseases affect rapidly due to coronavirus. This novel coronavirus attacks mainly on the person immunity. For the centuries the herbal medicinal plants have many beneficial effects against deadly viruses. Herbal medicines provide a rich resource for new antiviral drug development. These natural agents interact with the life cycle of virus such as virus entry, replication, assembly and release. In this review, the importance, immunomodulator, antiviral and pharmacological activities of some medicinal plants, namely, Allium Sativum, Zingiber Officinalis, Cinnamomum zeylanicum, Curcuma longa, Ocimum sanctum, Glycyrrhiza glabra, Ginseng, Black pepper, Emblica officinalis, Withania somnifera, Tinospora cordifolia, Echinacea purpurea, Azadirachta indica, Piper betel, Eugenia caryophyllata, Cinchona calisaya, Nigella sativa, Cuminum cyminum are highlighted. These medicinal plants have many phytoconstituents like alkaloids, glycosides, terpenoids, flavonoids, lactones, polysaccharides, volatile oils, tannins, resins, etc which are helpful for boosting immunity and will help in the prevention and in the management of COVID-19. Several types of research attempted to use herbal medicines against COVID-19.

IN VITRO LIPID PEROXIDATION INHIBITORY AND ANTI-ARTHRITIC ACTIVITIES OF SOME INDIAN MEDICINAL PLANTS

INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (06) ◽  
pp. 31-35
Author(s):  
A. A Rege ◽  
◽  
P. R. Juvekar ◽  
A. R. Juvekar
Keyword(s):  
Lipid Peroxidation ◽  
Liver Mitochondria ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum ◽  
Rat Liver Mitochondria ◽  
Total Phenolic ◽  
Lipid Peroxidation Inhibitory Activity ◽  
Gallic Acid Equivalent ◽  
Indian Medicinal Plants

Anti-lipid peroxidation effect of aqueous extracts of Ocimum sanctum, Tinospora cordifolia and Withania somnifera was evaluated against Fe2+-ascorbic acid-induced lipid peroxidation using rat liver mitochondria as model system, whereas, anti-arthritic activity was evaluated by proteinase inhibitory assay. O. sanctum showed potent anti-lipid peroxidation and anti-arthritic activities. T. cordifolia exhibited moderate anti-lipid peroxidation activity, but considerable anti-arthritic activity, whereas, W. somnifera revealed least lipid peroxidation inhibitory activity and considerable anti-arthritic activity. Besides, Folin-Ciocalteu reagent in terms of gallic acid equivalent achieved the total phenolic content and the trend was found to be O. sanctum > T. cordifolia > W. somnifera.

A Detailed Review on Herbal Treatments for Treatment of PCOS- Polycystic ovary syndrome (PCOS)

2021 ◽  
Vol 02 ◽  
Author(s):  
Ankita Wal ◽  
Pranay Wal ◽  
Nikita Saraswat ◽  
Simran Wadhwa
Keyword(s):  
Side Effects ◽  
Sleep Disturbances ◽  
Reproductive Age ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum ◽  
Tribulus Terrestris ◽  
Asparagus Racemosus ◽  
Anti Oxidant ◽  
Diseased Condition ◽  
Positive Effect

Background: The review gives a brief about PCOS and the symptoms related to the disease. Around 2.2 to 26% cases of PCOS are present globally. The disorder generally occurs in the reproductive age group women. The review has a mention of few herbs which can be used to correct the diseased condition. The various herbs have positive effect on the diseased condition and can be used to cure symptoms like hypothyroidism, hyperplasia, obesity, diabetes, Menorrhagia, sleep disturbances, cardiovascular problems, hyperlipidemia, hirsutism, infertility, irregular menstrual cycle, etc. The search engines used are PubMed, various review articles, etc. Methods: The method involved in the review includes various medicinal herbs that have seen to affect women having various gynecological disorders like Poly Cystic Ovarian Syndrome, Uterine Fibroids, and Endometriosis. Materials: The herbs included in the review include Bauhinia variegata useful in hormone imbalance, Phyllanthus emblica, Terminalia bellirica, Terminalia chebula, and Commiphora wightii are used to regulate the hormones, Cinnamon cassia acts as an anti-oxidant, Tribulus terrestris improves reproductive dysfunction, Hypericum perforatum regulates depression, Commiphora myrrha prevents menorrhagia, Nigella sativa controls cholesterol, Saraca asoca has estrogenic action, Asparagus racemosus promotes folliculogenesis, Tinospora cordifolia regulates menstrual flow, Ocimum sanctum as an anti-oxidant. Conclusion:: The plants taken had positive effect on women with PCOS without causing any side-effects. The natural herbs used for the treatment of PCOS did not have any side effects and treated the diseased condition naturally. The review is to understand the natural plants available for the treatment of the disease naturally. The herbs can be used individually or can be used in combination.

EVALUATION OF SOME MEDICINAL PLANTS AS PUTATIVE HIV-PROTEASE INHIBITORS

INDIAN DRUGS ◽  
2013 ◽  
Vol 50 (06) ◽  
pp. 24-28
Author(s):  
A.A Rege ◽  
◽  
A. S Chowdhary
Keyword(s):  
Inhibitory Activity ◽  
In Vitro Study ◽  
Hiv Protease ◽  
Tinospora Cordifolia ◽  
Ocimum Sanctum ◽  
Hiv Protease Inhibitors ◽  
Hiv Reverse Transcriptase ◽  
Anti Hiv ◽  
Potent Inhibitory Activity

Aqueous extracts of Ocimum sanctum Linn., Tinospora cordifolia (Willd.) Miers ex Hook. f. & Thoms, Withania somnifera Dunal, Avicennia officinalis Linn. and Rhizophora mucronata Lam. were included for the present in vitro study. Pepsin was used as a substitute for HIV-protease to evaluate inhibitory activity of these extracts, as pepsin has close resemblance with HIV-protease in proteolytic activity. O. sanctum revealed the highest inhibitory activity followed by R. mucronata. In our earlier study, O. sanctum and R. mucronata exerted anti-HIV activity via multiple mechanisms of action; viz., interference with the gp120 / CD4 interaction and inhibition of HIV-reverse transcriptase. In the present study, they also showed potent inhibitory activity against pepsin enzyme (indirectly against HIV-protease) which may be due their flavonoids content.

scholarly journals Mosquitocidal and water purification properties of Ocimum sanctum and Phyllanthus emblica

2012 ◽  
Vol 44 (3) ◽  
pp. 17 ◽  
Author(s):  
Kadarkarai Murugan ◽  
Pari Madhiyazhagan ◽  
Arjunan Nareshkumar ◽  
Thiyagarajan Nataraj ◽  
D. Dinesh ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Anopheles Stephensi ◽  
Activity Index ◽  
Secondary Compounds ◽  
Quality Parameters ◽  
Ocimum Sanctum ◽  
Human Consumption ◽  
Phyllanthus Emblica ◽  
Breeding Sites ◽  
Methanol Extracts

<em>Ocimum sanctum</em> was tested for its larvicidal and water sedimentation properties; the fruit ethanol and methanol extracts of <em>Phyllanthus emblica </em>were tested for phytochemical, larvicidal, oviposition-deterrent and ovicidal activities. Results emphasized that plant extracts have high toxicity against the egg and larvae of the malarial vector <em>Anopheles stephensi</em> and also have water sedimentation properties. LC<sub>50</sub> of <em>Phyllanthus emblica </em>against <em>Anopheles stephensi </em>larvae ranged from 33.08 ppm to 81.26 ppm and from 23.44 to 54.19 ppm for ethanol and methanol extracts, respectively. <em>Phyllanthus emblica</em> also showed excellent ovipositional deterrent and ovicidal activities. The oviposition activity index value of ethanol and methanol extracts of Phyllanthus emblica at 500 ppm were -0.80 and -0.92, respectively. <em>Ocimum sanctum</em> includes both insecticidal secondary compounds, amino acids (glycine, lysine), vitamin C and other substances, that make treated water suitable for human consumption. Water quality parameters such as color, turbidity and pH were analyzed in the water samples (pre-treatment and post-treatment of plant extracts) taken from the breeding sites of mosquitoes. Hence, the plant product can be used as both mosquitocidal and water purifier.

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