Black tea extracts influences indomethacin induced changes in renal histopathology of male albino rats

2017 ◽  
Vol 66 ◽  
pp. S11
Author(s):  
Ishwar B. Bagoji ◽  
M.A. Doshi ◽  
Saeed Yendigeri ◽  
B.G. Patil ◽  
Kusal K. Das
Keyword(s):  
Black Tea ◽  
Albino Rats ◽  
Renal Histopathology ◽  
Induced Changes

scholarly journals Black tea extract ameliorates indomethacin induced changes in testicular histopathology of albino rats

2014 ◽  
Vol 6 (3) ◽  
pp. 53-57
Author(s):  
Ishwar B Bagoji ◽  
Doshi MA ◽  
Saeed Yendigeri ◽  
Patil BG ◽  
Patil BB ◽  
...  
Keyword(s):  
Black Tea ◽  
Albino Rats ◽  
Black Tea Extract ◽  
Tea Extract ◽  
Induced Changes

Microarray reveals positive effects of green and black tea polyphenols on TNF[alpha]-induced changes of gene expression

2013 ◽  
Author(s):  
Husna Zulkipli ◽  
Norita Salim ◽  
Gabriele Anisah Froemming ◽  
Aletza Mohd Ismail ◽  
Hapizah Nawawi
Keyword(s):  
Gene Expression ◽  
Black Tea ◽  
Tea Polyphenols ◽  
Tnf Alpha ◽  
Positive Effects ◽  
Black Tea Polyphenols ◽  
Green And Black Tea ◽  
Induced Changes

A Study on the Effect of Samoa Extract (Cleome droserifolia) on Sperm Quality in Male Albino Rats Exposed to Pyrethroid

2021 ◽  
pp. 39-45
Author(s):  
Nura I. Al-Zail ◽  
Salah F. Kamies
Keyword(s):  
Sperm Quality ◽  
Group Iv ◽  
Male Rats ◽  
Control Group ◽  
Albino Rats ◽  
Protective Agent ◽  
Group V ◽  
Group Iii ◽  
Group I ◽  
Induced Changes

Pyrethroid cyhalothrin (PC) is an insecticide that is used worldwide for pest control in agriculture and household use. Samoa extract (SE) is a potent antioxidant protecting cells from oxidative stress. The present study investigates the protective and therapeutic effect of SE on PC-induced changes in sperm quality in male rats. Fifty adult male albino rats were divided into five groups: group I: served as control; group II: received PC i.p. only (6.2 mg/kg b.wt.); group III: received SE only (100 mg/kg b.wt., p.o.) for eight weeks; group IV: received SE as a protective agent daily for eight weeks, then followed by the administration of PC (i.p.) three times a week for two weeks; group V: exposed to PC (i.p.) three times a week for two weeks, then treated with the SE daily for 8 weeks. Results showed that PC caused markedly impaired sperm quality (a count, viability, motility, and abnormality). Compared to PC-treated animals, SE in the protective group markedly restored the alteration of sperm indices. However, SE in the curative group was found to be less effective in restoring PC-induced alterations. In conclusion, the data of this study revealed that the SE as a protective agent is more effective than as a therapeutic agent. Keywords: Samoa; Pyrethroid; Sperm quality; Rat

Atropine Sulphate Induced Changes in Uterine, Adrenal, Liver and Thyroid Gland in Female Albino Rats

2009 ◽  
Vol 4 (7) ◽  
pp. 236-245 ◽  
Author(s):  
Madhu M. Patil ◽  
Sharangouda J. Patil ◽  
Saraswati B. Patil
Keyword(s):  
Thyroid Gland ◽  
Albino Rats ◽  
Atropine Sulphate ◽  
Induced Changes

scholarly journals Assessment of the Protective Effect of Lepidium sativum against Aluminum-Induced Liver and Kidney Effects in Albino Rat

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Maha Jameal Balgoon
Keyword(s):  
Structural Changes ◽  
Lepidium Sativum ◽  
Albino Rats ◽  
Renal Tubules ◽  
Albino Rat ◽  
Antioxidant Power ◽  
Superior Effect ◽  
Ferric Reducing Antioxidant Power ◽  
Liver And Kidney ◽  
Induced Changes

Background and Objectives. Environmental pollution with the different Aluminum (Al) containing compounds has been increased. Liver and kidney are two vital organs targeted by Al accumulation. The aim of this study was to assess the possible protective and curative effects of Lepidium sativum Linn (LS) against Al-induced impairment of liver and kidney in albino rat and to explore the mechanism behind this effect. Materials and Methods. This experimental animal-based study included fifty albino rats divided into five groups, the control, LS-treated (20 mg/kg), AlCl3-treated (10 mg/kg), AlCl3 then LS, and AlCl3 plus LS-treated, simultaneously for 8 weeks. At the end of the experiment, hepatic and renal functions as well as the biomarkers of antioxidants activities were assessed in the serum. Both liver and kidney were dissected out and histopathologically examined. Results. This study showed that administration of AlCl3 caused a significant (p<0.05) reduction in rats body weight. It significantly increased serum AST, ALT, ALP, bilirubin, urea, and creatinine levels and decreased total protein and albumin. AlCl3 significantly reduced enzymatic (catalase), nonenzymatic (reduced glutathione), and ferric reducing antioxidant power (FRAP) in the serum. Histopathologically, it induced necrosis and degeneration of hepatocytes, glomeruli, and renal tubules. Administration of LS after or along with AlCl3 significantly restored the serum biomarkers of liver and kidney functions to their near-normal levels and had the ability to overcome Al-induced oxidative stress and preserved, to some extent, the normal hepatic and renal structure. The coadministration of LS had a superior effect in alleviating Al-induced changes. Conclusion. Exposure to AlCl3 induced a set of functional and structural changes in the liver and kidney of rats evident through both biochemical and histopathological assessment. The antioxidant activity of LS seeds mediated a protective and curative effect of LS against such changes. Further study through a rigorous clinical trial to prove LS activity on human is recommended.

PESTICIDE INDUCED CHANGES IN COAGULATION AND FIBRINOLYSIS IN EXPERIMENTAL ANIMALS

1987 ◽  
Author(s):  
Anjana Grover ◽  
K C Pandey ◽  
N K Satija ◽  
R M Rai
Keyword(s):  
Blood Coagulation ◽  
Chronic Exposure ◽  
Plant Protection ◽  
Exposure Period ◽  
Acute Exposure ◽  
Albino Rats ◽  
Chlorinated Pesticides ◽  
Experimental Animals ◽  
Induced Changes ◽  
Coagulation And Fibrinolysis

A relationship between the quality of environment and incidence of human health has been recognized in recent years. While the diseases such as carcinogenesis, respiratory diseases, skin disorders are often correlated with exposure to environmental toxins, the possibility of a link between blood coagulation and chemical contaminants in food, water and air has rarely been suspected. Wide usage of DDT in public health and plant protection programmes have led to a considerably higher levels of the pesticide in the blood and body fat of Indian population. Therefore, in order to explore the possibilities of an alteration in blood coagulation and fibrinolysis in response to pesticide insult, a study was undertaken in experimental animals.Adult male albino rats were administered technical grade DDT, 100 mg per kg body weight i.p. for 3 consecutive days for acute exposure study and fed food containing the pesticide at a concentration of 100 mg per kg diet for a duration of 90 days for chronic exposure. Coagulation and fibrinolytic status was assessed at the end of exposure period. Acute exposure to DDT significantly increased platelet count but decreased wall adherence of blood while chronic exposure to DDT elevated platelet counts by 21% and increased wall adherence of blood by 28%. Plasma clotting times were found to be shortened considerably both in acute and chronically exposed animals. DDT seemed to activate both extrinsic and intrinsic pathway of coagulation as evident by marked acceleration in prothrombin time and partial thromboplastin time. Plasma fibrinogen concentrations were found to be higher by 31.6% in rats given acute treatment but 40% lower in chronically exposed animals. A marked increase in fibrinolytic activity was observed in both acutely and chronically exposed animals. Thus, administration of chlorinated pesticides like DDT seemed to have a prothrombotic effect in experimental animals.

scholarly journals STUDY OF THE EFFECT OF H2O2 USED IN WHITENING TREATMENTS ON HUMAN ENAMEL WEAR RESISTANCE

2017 ◽  
Author(s):  
A. Branco ◽  
M. Polido ◽  
A.P. Serro ◽  
C.G. Figueiredo-Pina
Keyword(s):  
Wear Resistance ◽  
Black Tea ◽  
Solution Ph ◽  
Tooth Whitening ◽  
Ph Values ◽  
Human Enamel ◽  
Before And After ◽  
H2o2 Solution ◽  
Induced Changes ◽  
Enamel Wear

Tooth whitening treatments are based on the application of bleaching agents on the teeth surface, which can impair teeth health, due to its effect on enamel properties. The present work has the purpose of studying the effect of pH of H2O2 solutions on wear resistance of teeth. Friction coefficient, enamel microhardness, morphology and topography were also evaluated to better understand the induced changes. Three pH values (2, 4 and 6) of H2O2 solution were tested. First, human molars and premolars were disinfected, polished, cut in four equal pieces and darkened in a black tea solution. After, the teeth samples were bleached in 30% H2O2 solution with the different pH values. Vickers microhardness, surface roughness and wear measurements were performed before and after bleaching. The results showed that the enamel wear resistance depends on the solution pH: the lowest wear resistance was obtained for the sample bleached with H2O2 at pH 2.

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