Comparative study of combination therapy with Non-Steroidal Anti Inflammatory Drugs and different doses of low level laser therapy in acute low back pain

Background/Aim. The main clinical phenomena in acute low back pain (LBP) with radiculopathy are pain and neurological disorders. Although some studies show that low level laser therapy (LLLT) has the ability to modulate inflammatory processes and relieve acute pain condition, the laser therapy dose protocol has not been yet completely established. The aim of this study was to investigate the effects of three different energy doses of LLLT in patients with acute LBP and radiculopathy. Methods. The study included 66 patients with acute LBP and radiculopathy who had been randomly divided into three groups (22 patients each) received three different doses of LLLT. The patients were treated 5 times weekly, for a total of 10 treatments, with the following parameters: wave length 904 nm, frequency 3,000 Hz, average diode power 25 mW; energy dose of 0.1 J per point in the first group, 1 J per point in the second and 4 J per point in the third group; daily treatment time and accumulated energy were 16 s and 0.4 J in the first group, 160 s and 4 J in the second group and 640 s and 16 J in the third group, respectively. The parameters of assessment before and after the therapy were: lumbar and leg pain measured by visual analogue scale (VAS), local and general functional changes (Schober test, manual muscle test, straight leg raise test and the modified North American Spine Society-Low Back Pain Outcome Instrument-NASS LBP). Results. Highly significant improvements (p < 0.01) were noted in all the groups after LLLT with respect to all the investigated parameters. The VAS scores were significantly lower in all the groups without a difference between the groups (p > 0,05). Functional improvements were better in the third group treated with the dose of 4 J per point than in other two groups (p < 0.05). Conclusions. Three different energy doses of LLLT were equally effective in alleviating lumbar and leg pain without side effects, but the dose of 4 J per point seemed to be more effective in improving the activities of daily living and lumbar mobility.

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A Comparative Study on the Efficacy of Low Level Laser Therapy (LLLT) of Wavelength 905 NM and 808 NM in Management of Chronic Low Back Pain

Indian Journal of Physiotherapy and Occupational Therapy - An International Journal ◽

10.37506/ijpot.v15i4.16516 ◽

2021 ◽

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Comparative Study ◽

Laser Therapy ◽

Chronic Low Back Pain ◽

Low Level Laser Therapy ◽

Low Back ◽

Low Level ◽

Low Level Laser ◽

Level Laser

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A comparative study of aceclofenac versus etoricoxib in the management of acute low back pain in a tertiary care hospital

Journal of Drug Assessment ◽

10.1080/21556660.2020.1734008 ◽

2020 ◽

Vol 9 (1) ◽

pp. 60-65

Author(s):

Hema Jagannathan ◽

Amulya Thota ◽

Ashok Kumar B. Kumarappa ◽

Githa Kishore

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Comparative Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Low Back ◽

Acute Low Back Pain

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The effectiveness of low-level laser therapy for nonspecific chronic low back pain: a systematic review and meta-analysis

Arthritis Research & Therapy ◽

10.1186/s13075-015-0882-0 ◽

2015 ◽

Vol 17 (1) ◽

Cited By ~ 50

Author(s):

ZeYu Huang ◽

Jun Ma ◽

Jing Chen ◽

Bin Shen ◽

FuXing Pei ◽

...

Keyword(s):

Systematic Review ◽

Low Back Pain ◽

Back Pain ◽

Laser Therapy ◽

Chronic Low Back Pain ◽

Meta Analysis ◽

Low Level Laser Therapy ◽

Low Back ◽

Low Level Laser ◽

Level Laser

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Low-Level Laser Therapy including Laser Acupuncture for Non-Specific Chronic Low Back Pain: Systematic Review and Meta-Analysis

Journal of Acupuncture Research ◽

10.13045/jar.2020.00283 ◽

2021 ◽

Vol 38 (1) ◽

pp. 8-19

Author(s):

Hyewon Yeum ◽

Yejin Hong ◽

Dongwoo Nam

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Pain Relief ◽

Meta Analysis ◽

Low Level Laser Therapy ◽

Laser Acupuncture ◽

Low Back ◽

Significant Positive Effect ◽

Level Laser ◽

Positive Effect

Low-level laser therapy including laser acupuncture (LLLT/LA) has been widely used for non-specific chronic low back pain (NCLBP). However, there is no critically appraised evidence of its potential benefits. This study aimed to evaluate the effectiveness of LLLT/LA for NCLBP. There were 12 databases (MEDLINE, CENTRAL, EMBASE, KoreaMed, KMBASE, KISS, NDSL, KISTI, OASIS, CNKI, CiNII, J-stage) searched for randomized controlled trials using LLLT/LA for NCLBP up until June 2019. The primary outcome was pain intensity and functional status/disability due to NCLBP. A random-effects meta-analysis was conducted on 20 studies involving 1,323 participants. LLLT/LA showed a significant positive effect on pain relief scores compared with sham treatments (SMD -0.51, 95% CI: -0.88 to -0.13; χ2 = 31.12, I2 = 74%). Alone, the therapy showed a significant positive effect on function/disability scores (30 participants, MD -11.90, 95% CI: -17.37 to -6.43). As an add-on treatment, it showed a significant positive effect on pain relief (80 participants, MD -5.10, 95% CI: -9.31 to -0.88; χ2 = 28.99, I2 = 97%) and improved function/disability scores (120 participants, MD 5.44, 95% CI: 2.19 to 8.68; χ2 = 4.07, I2 = 75%). Among 20 studies, 9 studies reported no adverse events and 1 study reported mild adverse events. LLLT/LA may be an alternative or add-on treatment for NCLBP.

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A COMPARATIVE STUDY ON EFFICACY AND SAFETY OF TOLPERISONE VERSUS TIZANIDINE IN PATIENTS SUFFERING FROM ACUTE LOW BACK PAIN WITH MUSCLE SPASM

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2021.v14i12.43295 ◽

2021 ◽

pp. 153-157

Author(s):

ABDUL FAHEEM KHAN ◽

KHANETA PARVEEN

Keyword(s):

Low Back Pain ◽

Back Pain ◽

Comparative Study ◽

Clinical Symptoms ◽

Mean Value ◽

Muscle Spasm ◽

Low Back ◽

Efficacy And Safety ◽

Acute Low Back Pain ◽

Significant Difference

OBJECTIVES: The objectives of this study were to compare the efficacy and safety of Tolperisone tablets 50 mg three times daily versus Tizanidine 2 mg tablets thrice daily for the treatment of acute low back pain with muscle spasm. METHODS: The comparative study was carried out in 50 patients from orthopedics Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Vijayawada. Only those patients fulfilling the inclusion/exclusion criteria were enrolled into the study. Participants suffering from acute low back pain with muscle spasm were divided into two groups. The participants were followed up on Day-14 as final analysis. RESULTS: Subjects receiving Tolperisone showed a mean value of 16.43±1.16 in the Roland Morris low back pain and disability questionnaire both groups on day 1 and was reduced to 7.82±1.15 (51.94%) on day 7 and 2.56±1.53 (84.46%) on day 14. Similarly, the patients in the tizanidine group had mean value of 15.93±1.61 on day 1, which was reduced to 6.77±1.68 (57.64%) on day 7, and 2.88±1.92 (81.95%) on day 14, as comparable to the Tolperisone group. There was no statistically significant difference between the two groups, (p>0.05) for pain at rest, pain at night, restrictions of movement, changes in stiffness, changes in numbness, and changes in tenderness. There was a statistically significant difference between the two groups, (p<0.05) for pain on movement and kinesalgia. CONCLUSIONS: Tolperisone was found comparable in efficacy to Tizanidine in improving the clinical symptoms of changes in pain Self-assessment by the patient on different applied parameters.

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A Randomized Comparative Study between High-Intensity and Low-Level Laser Therapy in the Treatment of Chronic Nonspecific Low Back Pain

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2020/1350281 ◽

2020 ◽

Vol 2020 ◽

pp. 1-6

Author(s):

Walid Kamal Abdelbasset ◽

Gopal Nambi ◽

Saud F. Alsubaie ◽

Ahmed M. Abodonya ◽

Ayman K. Saleh ◽

...

Keyword(s):

Quality Of Life ◽

Low Back Pain ◽

Back Pain ◽

Laser Therapy ◽

High Intensity ◽

Low Level Laser Therapy ◽

Control Group ◽

Low Back ◽

Level Laser

Objectives. Chronic nonspecific low back pain (chronic nsLBP) is one of the most common musculoskeletal disorders leading to disabilities and physical inactivity. Laser therapy was used in chronic nsLBP treatment; however, no previous studies have assessed the impacts of high-intensity laser therapy (HILT) versus low-level laser therapy (LLLT) on chronic nsLBP. This study compared the effects of HILT versus LLLT on individuals suffering from chronic nsLBP. Methods. The study was a randomized control trial. Sixty individuals with chronic nsLBP were enrolled in this study between May and November 2019. All participants were clinically diagnosed with chronic nsLBP. They were assigned randomly into three groups, 20 in each group. The first group received a program of LLLT, the second group received a program of HILT, and the third did not receive laser therapy (control group). Pain severity, disability, lumbar mobility, and quality of life were assessed before and after 12-week intervention. Results. Both LLLT and HILT groups showed a significant improvement of the Oswestry Disability Index (ODI), visual analogue scale (VAS), lumbar range of motion (ROM), and European Quality of Life (EuroQol) scores ( p > 0.05 ), while the control group did not show significant changes ( p > 0.05 ). Comparison among the three study groups postintervention showed significant differences in the outcome measures ( p > 0.05 ), while comparison between the LLLT and HILT groups showed nonsignificant differences ( p > 0.05 ). Conclusion. There are no different influences of LLLT versus HILT on chronic nsLBP patients. Both LLLT and HILT reduce pain and disability and improve lumbar mobility and quality of life in chronic nsLBP patients.

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