scholarly journals A COMPARATIVE STUDY ON EFFICACY AND SAFETY OF TOLPERISONE VERSUS TIZANIDINE IN PATIENTS SUFFERING FROM ACUTE LOW BACK PAIN WITH MUSCLE SPASM

2021 ◽  
pp. 153-157
Author(s):  
ABDUL FAHEEM KHAN ◽  
KHANETA PARVEEN
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Comparative Study ◽  
Clinical Symptoms ◽  
Mean Value ◽  
Muscle Spasm ◽  
Low Back ◽  
Efficacy And Safety ◽  
Acute Low Back Pain ◽  
Significant Difference

OBJECTIVES: The objectives of this study were to compare the efficacy and safety of Tolperisone tablets 50 mg three times daily versus Tizanidine 2 mg tablets thrice daily for the treatment of acute low back pain with muscle spasm. METHODS: The comparative study was carried out in 50 patients from orthopedics Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Vijayawada. Only those patients fulfilling the inclusion/exclusion criteria were enrolled into the study. Participants suffering from acute low back pain with muscle spasm were divided into two groups. The participants were followed up on Day-14 as final analysis. RESULTS: Subjects receiving Tolperisone showed a mean value of 16.43±1.16 in the Roland Morris low back pain and disability questionnaire both groups on day 1 and was reduced to 7.82±1.15 (51.94%) on day 7 and 2.56±1.53 (84.46%) on day 14. Similarly, the patients in the tizanidine group had mean value of 15.93±1.61 on day 1, which was reduced to 6.77±1.68 (57.64%) on day 7, and 2.88±1.92 (81.95%) on day 14, as comparable to the Tolperisone group. There was no statistically significant difference between the two groups, (p>0.05) for pain at rest, pain at night, restrictions of movement, changes in stiffness, changes in numbness, and changes in tenderness. There was a statistically significant difference between the two groups, (p<0.05) for pain on movement and kinesalgia. CONCLUSIONS: Tolperisone was found comparable in efficacy to Tizanidine in improving the clinical symptoms of changes in pain Self-assessment by the patient on different applied parameters.

scholarly journals Efficacy and tolerability of eperisone versus tizanidine in patients suffering from low back pain with muscle spasm

2017 ◽  
Vol 5 (6) ◽  
pp. 2694
Author(s):  
Abdul F. Khan ◽  
Khaneta Parveen ◽  
Abdul S. Khan
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Signs And Symptoms ◽  
Mean Value ◽  
Muscle Spasm ◽  
Muscle Stiffness ◽  
Low Back ◽  
Statistical Significant Difference ◽  
Significant Difference ◽  
Pain At Rest

Background: Low back pain (LBP), a high prevalent condition, is usually associated with 'muscle spasm' that is responsible for giving rise to pain. Eperisone hydrochloride is widely used for treatment associated muscle stiffness and pain. The aim of the study was to compare the efficacy and safety of eperisone tablets 50 mg three times daily versus tizanidine 2 mg tablets thrice daily for the treatment of low back pain with muscle spasm.Methods: The study was carried in 50 patients from a private hospital at Mumbai. Only patients satisfying the inclusion criteria were enrolled into the study. Subjects suffering from low back pain with spasm were divided in two groups. The patients were then followed up on Day-14.Results: Patients receiving eperisone showed a mean value of 16.48±1.15 in the Roland Morris low back pain and disability questionnaire both groups on day 1 and was reduced to 7.92±1.15 (51.94%) on day 7 and 2.56±1.53 (84.46%) on day 14. Similarly, the patients in tizanidine group had mean value of 15.96±1.62 on day 1, which was reduced to 6.76±1.66 (57.64%) on day 7, and 2.88±1.92 (81.95%) on day 14, as similar to eperisone group. There was no statistical significant difference between the two groups, (p>0.05) for pain at rest, pain at night, restriction of movement, changes in stiffness, changes in numbness and changes in tenderness. There was statistical significant difference between the two groups, (p<0.05) for pain on movement and kinesalgia.Conclusions: Eperisone was found to be comparable to Tizanidine in improving the signs and symptoms of changes in pain Self-assessment by the patient on different applied parameters.

scholarly journals Efficacy and Safety of Acupuncture for Acute Low Back Pain in Emergency Department: A Pilot Cohort Study

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Yen-Ting Liu ◽  
Chih-Wen Chiu ◽  
Chin-Fu Chang ◽  
Tsung-Chieh Lee ◽  
Chia-Yun Chen ◽  
...  
Keyword(s):  
Emergency Department ◽  
Cohort Study ◽  
Low Back Pain ◽  
Back Pain ◽  
Control Group ◽  
Low Back ◽  
Efficacy And Safety ◽  
Acute Low Back Pain ◽  
Significant Difference ◽  
Experimental Group

Introduction. Low back pain (LBP) is one of the most common complaints in the emergency department (ED). There are several research articles providing evidence for acupuncture for treating chronic LBP but few about treating acute LBP. This study assessed the efficacy and safety of acupuncture for the treatment of acute LBP in the ED.Materials and methods. A clinical pilot cohort study was conducted. 60 participants, recruited in the ED, were divided into experimental and control groups with 1 dropout during the study. Life-threatening conditions or severe neurological defects were excluded. The experimental group (n=45) received a series of fixed points of acupuncture. The control group (n=14) received sham acupuncture by pasting seed-patches near acupoints. Back pain was measured using the visual analog scale (VAS) at three time points: baseline and immediately after and 3 days after intervention as the primary outcome. The secondary outcomes were heart rate variability (HRV) and adverse events.Results. The VAS demonstrated a significant decrease (Pvalue <0.001) for the experimental group after 15 minutes of acupuncture. The variation in HRV showed no significant difference in either group. No adverse event was reported.Conclusion. Acupuncture might provide immediate effect in reducing the pain of acute LBP safely.

scholarly journals To Study the effect of Traditional Back Exercises vs Exercise Ball Exercise on Pain Intensity, Core Endurance and Limitation of Activities in Individuals with Nonspecific Low Back Pain: A Comparative Study

2021 ◽  
pp. 117-123
Author(s):  
Jay Kumar Soni ◽  
Edrish Contractor
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Comparative Study ◽  
Pain Intensity ◽  
Core Stability ◽  
Low Back ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Swiss Ball

Aims: Non specific Low back pain is defined as pain without any known pathology which affects almost all the leading occupation where body's awkward posture, twisting and stress forces are commonly encountered across the globe and it is highly prevalent 60% to 70% in a year. Studies have shown various exercise regimen individual effect on the same but superiority of regimen out of these is not clear. Study Design: Comparative Study Place and Duration of Study: Ahmedabad Institute of Medical Sciences, Duration 2013-15 Objective: To assess and compare the effect of core stability exercise, back school program and Swiss ball exercise on Pain, core endurance and Functional disability. Methodology: A group of 24 patients having non-specific low back pain between age groups 18-40 were randomly selected and allocated in to two groups. Group A(n=12) received traditional exercise whereas Swiss ball exercise was given to Group B(n=12). The subjects were treated for two weeks. Baseline data for VAS, Core endurance and MODI were taken on day1 and at the end of two weeks Result: The results were analyzed by wilcoxon signed rank test within both groups. Both groups showed significant improvement in VAS, core endurance and MODI at the end of 2weeks.Comparison between both the Group A and Group B was done by Mann- whitney U test and statistically no significant difference was seen in VAS, core endurance and MODI between the groups Conclusion: The study concluded that both the exercises are equally effective in reducing pain intensity, improves core endurance and functional status in subjects with non specific low back pain

scholarly journals Efficacy and Safety of Combination of NSAIDs and Muscle Relaxants in the Management of Acute Low Back Pain

2019 ◽  
Vol 8 (1) ◽  
pp. 121-132 ◽  
Author(s):  
Himanshu D. Patel ◽  
R. B. Uppin ◽  
A. Ramakrishnam Naidu ◽  
Y. Ratnakar Rao ◽  
Suhas Khandarkar ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Muscle Relaxants ◽  
Low Back ◽  
Efficacy And Safety ◽  
Acute Low Back Pain

scholarly journals Effect of muscle energy technique with and without strain–counterstrain technique in acute low back pain — A randomized clinical trial

2018 ◽  
Vol 38 (01) ◽  
pp. 41-51
Author(s):  
Vivek Dineshbhai Patel ◽  
Charu Eapen ◽  
Zulfeequer Ceepee ◽  
Ramachandra Kamath
Keyword(s):  
Clinical Trial ◽  
Low Back Pain ◽  
Back Pain ◽  
Randomized Clinical Trial ◽  
Low Back ◽  
Acute Low Back Pain ◽  
Muscle Energy Technique ◽  
Difference Formula ◽  
Significant Difference ◽  
Muscle Energy

Background: Muscle energy technique (MET) and strain–counterstrain (SCS) technique are found to be effective as a sole treatment of acute low back pain (LBP), but the combined effect of these two techniques has not been evaluated. Objective: The purpose of this randomized clinical trial was to evaluate the added effect of SCS to MET in acute LBP patients. Methods: In this trial, 50 patients were randomly allocated to MET or MET-SCS group to receive the assigned two treatment sessions for two consecutive days. Oswestry disability index (ODI) and Roland Morris disability questionnaire (RMDQ), visual analogue scale (VAS), lumbar range of motion (ROM) were recorded at baseline, after first and second session. Results: All the outcome measures showed statistically significant ([Formula: see text]) improvement in both the groups after second session. Between the groups, analysis showed no statistically significant difference ([Formula: see text]) after the first or second session. Conclusions: The improvement after second treatment sessions was noted in pain, ROM, and disability in both the groups, but immediate effect was seen only on pain intensity after first treatment session. When compared between the groups, no added effect of SCS to MET was found in reducing pain and disability and increasing lumbar ROM in acute LBP patients.

Three-dimensional reconstruction of intervertebral disc based on magnetic resonance imaging in patients with acute low back pain

2021 ◽  
Author(s):  
T Kotwicki ◽  
S Rubczak ◽  
P Glowka
Keyword(s):  
Magnetic Resonance Imaging ◽  
Low Back Pain ◽  
Back Pain ◽  
Magnetic Resonance ◽  
Intervertebral Disc ◽  
Clinical Symptoms ◽  
Low Back ◽  
Resonance Imaging ◽  
Acute Low Back Pain ◽  
Dimensional Reconstruction

The aim of the study is to evaluate the morphology of the intervertebral discs visible in the magnetic resonance image in patients with sudden severe low back pain (with or without radiation of pain to the lower limb). The second goal of the study is to perform a digital three-plane reconstruction of the intervertebral disc and to compare this technique with a standard magnetic resonance imaging test. Twenty-five patients, mean age 35.5 years, all with acute low back pain, were examined. We compared the 3D MR models with standard MRI scans by measuring seven MRI parameters. In patients with sudden, severe low back pain, with clinical symptoms suggesting an etiology within the intervertebral disc, changes in a standard MRI are found consisting of the presence of a hernia / protrusion of the intervertebral disc and lowering the height of the intervertebral disc – with lowering the disc height occurs to a greater extent in the rear section. The 3D reconstruction is a reliable 3D representation of the intervertebral disc and adjacent vertebral bodies.

scholarly journals Aceclofenac–tizanidine in the treatment of acute low back pain: a double-blind, double-dummy, randomized, multicentric, comparative study against aceclofenac alone

2009 ◽  
Vol 18 (12) ◽  
pp. 1836-1842 ◽  
Author(s):  
Anil Pareek ◽  
Nitin Chandurkar ◽  
A. S. Chandanwale ◽  
Ratnakar Ambade ◽  
Anil Gupta ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Comparative Study ◽  
Low Back ◽  
Double Blind ◽  
Acute Low Back Pain
Sign in / Sign up

Export Citation Format

Share Document