Mouse Preputial Gland Abscesses: An Old but Actual Problem – Aetiology and Management

2020 ◽  
Vol 174 ◽  
pp. 153
Author(s):  
M. de Mik-van Mourik ◽  
E.N. Speksnijder ◽  
R.A. Fleming ◽  
S. van der Wal-Maas ◽  
S. Gerhardt ◽  
...  
2019 ◽  
Vol 7 (1) ◽  
pp. 9-20
Author(s):  
Inna Yeung

Choice of profession is a social phenomenon that every person has to face in life. Numerous studies convince us that not only the well-being of a person depends on the chosen work, but also his attitude to himself and life in general, therefore, the right and timely professional choice is very important. Research about factors of career self-determination of students of higher education institutions in Ukraine shows that self-determination is an important factor in the socialization of young person, and the factors that determine students' career choices become an actual problem of nowadays. The present study involved full-time and part-time students of Institute of Philology and Mass Communications of Open International University of Human Development "Ukraine" in order to examine the factors of career self-determination of students of higher education institutions (N=189). Diagnostic factors of career self-determination of students studying in the third and fourth year were carried out using the author's questionnaire. Processing of obtained data was carried out using the Excel 2010 program; factorial and comparative analysis were applied. Results of the study showed that initial stage of career self-determination falls down on the third and fourth studying year at the university, when an image of future career and career orientations begin to form. At the same time, the content of career self-determination in this period is contradictory and uncertain, therefore, the implementation of pedagogical support of this process among students is effective.


The article is devoted to the actual problem of assigning optimal parameters for connecting steel plates on cover plates with angular welds that are widely used in construction practice. The article presents the results of a comprehensive study of operation of a welded assembly of the plates connection on cover plates. An algorithm is proposed for determining the optimal parameters of a welded joint with fillet welds on the cover plates, which makes it possible to obtain a strength balanced connection. The results of full-scale tensile tests of models were presented. These results confirmed the correctness of the assumed design assumptions, and made it possible to obtain a form of destruction, not characteristic and not described in the normative literature, expressed by cutting the main elements along the length of the overlap in the joint. The possibility of such a form of destruction was confirmed by the results of numerical research in a nonlinear formulation. The optimal parameters of the nodal welded joint determined by engineering calculation are confirmed by experimental studies, as well as by the results of numerical experiments on models of calculation schemes, taking into account the physical nonlinearity of the material operation. The obtained dependence for determining the bearing capacity of the joint by the cut-off mechanism and the expression for limiting the overlap length of the cover plates will make it possible to predict the nature of the fracture and design equally strong joints.


In construction production, the safety of constructing buildings and structures is achieved by ensuring the required quality as a result of systematic construction control based on the implementation of a complex of technical, economic and organizational measures at all stages of the object's life cycle. The article deals with the actual problem of improving the quality of construction products-buildings and structures in conjunction with the activities of construction control bodies. The article presents the advanced foreign and domestic experience of ensuring the quality control at the construction sites, providing for the prevention of the underlying causes of defects and increasing the interest of the contractors directly. On the basis of the analysis of the current situation with quality control at the construction market, ways to improve its efficiency by developing a unified system of technological implementation of relevant requirements for the quality of construction products, determining the rational number and business load of construction control engineers, as well as the active activities of self-regulatory organizations in this area are offered.


2020 ◽  
pp. 105-118
Author(s):  
Zoryana Кupchyns’ka

Proper names of people as creating stems are represented in oiconymy of Ukraine. Anthroponymy separated from o iconymy of Ukraine ending in *-inъ is only a small fragment of a large amount of proper names and their variants. The actual problem is creating the dictionary of personal names of people, which would contain anthroponymy derived from archaic oiconymy. It would enrich not only the Ukrainian anthroponymicon but AllSlavonic one. 251 anthroponym of canonical origin is distinguished from geographical names of Ukraine ending in *-inъ. Most of Christian anthroponyms are represented in dictionaries as names of people or as bynames/proto-surnames. It is found out that 30 names (12%) are not represented in lexicographical works: Аврата (< Гаврило), Горпа (< Агрипина//Горпина), Демх(ш)а (< Дем’ян), Домашла (< Домна, Домнікія, Домаха), Ільпа (< Ілля), Кузята (< Кузьма), Макиш(х)а (< Матвій, розм. Макій), Макош(х)а (< Матвій, розм. Макій), Манята (< Марія), Мар’ята (< Мар’яна), Матюш(х)а (< Матвій), Митула (< Дмитро), Михла (< Михайло), Мишера (< Михайло), Мишута (< Михайло), Нита(я) (< Нит), Ол(ъ)ма (< Олъма), Панчоха (< Пантелеймон), Парута (< Парасковія), Пилипчата (< Пилип), Савара (< Север, Северин), Стеська (< Степан), Таша (< Наталія), Теола (< Теофіла, Феофіла), Тимота (< Тимофій), Томара (< Тамара), Фетюха (< Федір), Юриця (< Юрій), Якота (< Яків), Янкулиха (< Ян).


2020 ◽  
Vol 24 (1) ◽  
pp. 60-66
Author(s):  
I. V. Lavrishcheva ◽  
A. Sh. Rumyantsev ◽  
M. V. Zakharov ◽  
N. N. Kulaeva ◽  
V. M. Somova

BACKGROUND. The lack of data on the epidemiology of presarcopenia/sarcopenia leads to an underestimation of the role of this condition in the structure of morbidity and mortality of haemodialysis patients in theRussian Federation. THE AIM: to study the epidemiological aspects of presarcopenia /sarcopenia in patients with chronic kidney disease stage 5d. PATIENTS AND METHODS. This study comprised 317 patients receiving programmed bicarbonate haemodialysis for 8.2 ± 5.1 years, among them 171 women and 146 men, the average age was 57.1 ± 11.3 years. The assessment of the presence of sarcopenia was performed using the method recommended by the European Working Group on Sarcopenia in Older People. RESULTS. The prevalence of presarcopenia was 0.7 % and sarcopenia 29.6 %. The incidence of skeletal muscle mass deficiency according to muscle mass index (IMM) was 30.3 %, 48.7 % showed a decrease in muscle strength according to dynamometry, and low performance of skeletal muscles according to 6 minute walk test was determined in 42.8 %. Sarcopenia patients were significantly characterized by lower body mass index, as well as higher body fat mass values. The duration of haemodialysis (χ2 = 22.376, p = 0.0001) and the patient's age (χ2 = 10.545 p = 0.014) were an independent risk factors for the development of sarcopenia. CONCLUSION. Sarcopenia is recorded more frequently in hemodialysis patients than presarcopenia. Its prevalence increases among patients of older age groups and with a hemodialysis duration of more than 5 years. The age and experience of dialysis make their independent contribution to the development of this syndrome.


2017 ◽  
Vol 63 (1) ◽  
pp. 141-145
Author(s):  
Yuliya Khochenkova ◽  
Eliso Solomko ◽  
Oksana Ryabaya ◽  
Yevgeniya Stepanova ◽  
Dmitriy Khochenkov

The discovery for effective combinations of anticancer drugs for treatment for breast cancer is the actual problem in the experimental chemotherapy. In this paper we conducted a study of antitumor effect of the combination of sunitinib and bortezomib against MDA-MB-231 and SKBR-3 breast cancer cell lines in vitro. We found that bortezomib in non-toxic concentrations can potentiate the antitumor activity of sunitinib. MDA-MB-231 cell line has showed great sensitivity to the combination of bortezomib and sunitinib in vitro. Bortezomib and sunitinib caused reduced expression of receptor tyrosine kinases VEGFR1, VEGFR2, PDGFRa, PDGFRß and c-Kit on HER2- and HER2+ breast cancer cell lines


Author(s):  
Vitaliy Voronov ◽  
Timur Slivin

В статье рассмотрена актуальная проблема перевоспитания военнослужащих в дисциплинарных частях в Российской империи как организованного и структурированного процесса. Изучено использование их потенциала для поддержания дисциплины и правопорядка среди личного состава. Определено, что к военнослужащим предусмотрено применение специальных видов уголовных наказаний, кроме того, допускается изъятие в применении отдельных наказаний к данной категории лиц. Авторами раскрывается порядок реализации наказания в виде лишения свободы в частях с воинской организацией в отношении военнослужащих, совершивших преступления. Указывается на то, что перевоспитание осужденных военнослужащих было направлено на повышение уровня их военной и строевой подготовки, принуждение их к выполнению требований военной присяги и воинских уставов. В качестве негативного момента перевоспитания осужденных военнослужащих указывается отсутствие специальной подготовки у штатных офицеров и нижних чинов дисциплинарных частей. В статье рассматривается порядок реализации наказания в виде лишения свободы в арестантских частях, а также дисциплинарных частях. Раскрыто понятие арестантских рот, их руководящий и личный состав, а также порядок содержания осужденных. Показаны особенности комплектования дисциплинарных частей как постоянным составом, так и переменным (осужденными), а также прохождения ими службы. Авторами отмечается, что в перевоспитании осужденных военнослужащих превалировала принудительная функция в ущерб нравственному воздействию. Авторы приходят к выводу о том, что дисциплинарные и штрафные части со строевой организацией в целом справляются с задачей перевоспитания осужденных военнослужащих, а опыт функционирования дисциплинарных частей царской армии был использован при создании военно-карательного аппарата Советской армии.The article deals with the actual problem of re-education of military personnel in disciplinary units in the Russian Empire as an organized and structured process. The use of their potential for maintaining discipline and law enforcement among personnel was studied. It is determined that the use of special types of criminal penalties is provided for military personnel, in addition, exceptions are allowed in the application of certain penalties to this category of persons. The author reveals the order of realization of punishment in the form of imprisonment in re-lations with the military organization in relation to the military personnel who have committed crimes. It is pointed out that the re-education of convicted servicemen was aimed at increasing the level of their military and drill training, forcing them to fulfill the requirements of the military oath and military regulations. As a negative aspect of the re-education of convicted servicemen, the lack of special training of regular officers and lower ranks of disciplinary units is indicated. The article deals with the procedure for the implementation of punishment in the form of im-prisonment in prison units, as well as disciplinary units. The concept of convict companies, their leadership and personnel, as well as the order of detention of convicts is revealed. The peculiarities of completing disciplinary units with both permanent and variable composition (convicts), as well as their service are shown. The author notes that in the re-education of convicted servicemen, forced functioning prevailed to the detriment of moral influence. The author comes to the conclusion that disciplinary and penal units with drill organization in General cope with the task of re-education of convicted servicemen, and the experience of functioning of disciplinary units of the tsarist army was used in the creation of the military punitive apparatus of the Soviet army.


Author(s):  
Олег Петунин ◽  
Oleg Petunin

<p>The article is devoted to an actual problem of integration of school courses in physics, chemistry, biology, ecology and physical geography. The author analyzes the content of the concept of integration of science education and enumerates the positive effects of its implementation. The article also presents the three levels of the integration: intra-, inter- and transdisciplinary. The author thoroughly describes methods of interdisciplinary integration, stopping on interdisciplinary communication, integrated lessons and integrated courses. The article revealed issues of interdisciplinary integration and suggest ways to overcome them. In conclusion, the author comes to the conclusion that the integration of science education is an urgent 9mki0problem of general education. To date, there are a number of successful solutions for this problem. In this article we have tried to summarize some material on this issue.</p>


1986 ◽  
Vol 83 (19) ◽  
pp. 7292-7296 ◽  
Author(s):  
Y. Nishimura ◽  
M. G. Rosenfeld ◽  
G. Kreibich ◽  
U. Gubler ◽  
D. D. Sabatini ◽  
...  

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