scholarly journals Insulin resistance in Saudi postmenopausal women with and without metabolic syndrome and its association with vitamin D deficiency

2015 ◽  
Vol 2 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Eman M. Alissa ◽  
Wafa A. Alnahdi ◽  
Nabil Alama ◽  
Gordon A. Ferns
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Postmenopausal Women

Association between vitamin D deficiency and the risk factors for metabolic syndrome in postmenopausal women

Maturitas ◽  
2017 ◽  
Vol 100 ◽  
pp. 185-186
Author(s):  
Eneida Schmitt ◽  
Jorge Nahas-Neto ◽  
Flavia Bueloni-Dias ◽  
Priscila Poloni ◽  
Ana Laura Lucca ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Postmenopausal Women

scholarly journals Relationship of arterial hypertension, metabolic syndrome with vitamin D deficiency in women

2020 ◽  
Vol 43 (4) ◽  
pp. 549-559
Author(s):  
Lyudmila V. Vasilieva ◽  
◽  
Yuliya V. Tatarintseva ◽  
Elena V. Gosteva ◽  
Sergej Y. Popov ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Arterial Hypertension ◽  
Blood Serum ◽  
Vitamin D Deficiency ◽  
Postmenopausal Women ◽  
Blood Pressure Monitoring ◽  
Low Hdl ◽  
Relationship Of ◽  
The Relationship

Objective: To assess the relationship between vitamin D deficiency (VD) and risk factors for metabolic syndrome (MS) in postmenopausal women with arterial hypertension (AH). Materials and methods of research. The study included 46 women aged 45–65 years with amenorrhea > 12 months, having grade 1 hypertension and metabolic syndrome. Anthropometric, laboratory and instrumental data were studied. Biochemical parameters included total cholesterol (OH), HDL, triglycerides, glucose, insulin, and 25-hydroxyvitamin-D [25 (OH)D]. Daily blood pressure monitoring was performed according to the standard protocol. Levels of 25(OH)D in blood serum was classified as-adequate (≥ 30 ng/ml) and insufficient (20–29 ng/ml). Results: Level 25 (OH)D in blood serum was sufficient in 21 women (45.6 %), insufficient – in 25 (54.4 %). Women with insufficient levels of 25 (OH)D had higher levels of cholesterol, triglycerides, insulin, and HOMA-IR. Metabolic syndrome was detected in 64 % (16/25) of women with hypovitaminosis D and in 43 % (9/21) of women with sufficient VD (p < 0.01). The correlation analysis established the relationship of the low level of 25 (OH)D (< 30 ng / ml) with MS (r = 0.68), high triglycerides (r = 0.74) and low HDL (r = 0.71). The average concentration of 25 (OH) D decreased with an increase in the number of MS components (p = 0.016). Conclusions: VD deficiency in postmenopausal women was associated with a higher prevalence of MS. Women with HDL deficiency had a higher risk of MS, hypertriglyceridemia, and low HDL levels compared to those with adequate levels.

scholarly journals Vitamin D deficiency is associated with metabolic syndrome in postmenopausal women

Maturitas ◽  
2018 ◽  
Vol 107 ◽  
pp. 97-102 ◽  
Author(s):  
Eneida Boteon Schmitt ◽  
Jorge Nahas-Neto ◽  
Flavia Bueloni-Dias ◽  
Priscila Ferreira Poloni ◽  
Claudio Lera Orsatti ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Postmenopausal Women

scholarly journals Relationship between Serum Vitamin D Levels and HDL Cholesterol in Postmenopausal Women from Colombian Caribbean

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Luz Adriana Sarmiento-Rubiano ◽  
José Armando Angarita Ruidiaz ◽  
Héctor Fernando Suarez Dávila ◽  
Alfonso Suarez Rodríguez ◽  
Roberto C. Rebolledo-Cobos ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Postmenopausal Women ◽  
Serum Vitamin ◽  
Hdl Cholesterol ◽  
Serum Vitamin D ◽  
The Metabolic Syndrome ◽  
Increased Risk ◽  
Vitamin D Levels

Background. Previous evidence suggests that metabolic disorders in postmenopausal women could be related with low serum vitamin D levels. For example, vitamin D deficiency has been associated with increased risk factors for cardiovascular disease (CVD), mainly those related with metabolic syndrome.Objective. To assess the relationship between the serum vitamin D (25-OH-D) levels and the metabolic syndrome markers in postmenopausal women.Methods. This descriptive and cross-sectional study was conducted in 183 postmenopausal women of four municipalities from Colombian Caribbean. The serum 25-OH-D levels and the anthropometric and biochemical markers were assessed and correlated with metabolic syndrome.Results. The average value of serum vitamin D (25-OH-D) was 26.34 ± 9.08 ng/mL, and 69.95% of the women had vitamin D levels <30 ng/mL, of which 43.72% were with insufficiency (<30 to >20 ng/mL) and 26.23% with deficiency (<20 ng/mL). Of the evaluated women, the 81.42% seemed to have metabolic syndrome. Through the linear regression, one significant positive association was observed between the HDL cholesterol and the 25-OH-D levels (P=0.014).Conclusion. In the evaluated population in this study, vitamin D deficiency is related with low HDL cholesterol levels.

scholarly journals Vitamin D and polycystic ovary syndrome: an integrating review

10.3823/2402 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Ione Maria Ribeiro Soares Lopes ◽  
Caroliny Gonçalves Rodrigues Meireles ◽  
Iarlla Silva Ferreira ◽  
Nadya Dos Santos Moura ◽  
Francisca Diana Da Silva Negreiros ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Vitamin D ◽  
Polycystic Ovary Syndrome ◽  
Vitamin D Deficiency ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Ovary Syndrome ◽  
Controversial Subject

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrinopathyin women of reproductive age. It causes a metabolic syndrome characterized by insulin resistance, hyperinsulinemia, and dyslipidemia. Vitamin D deficiency and its association with PCOS still represents a controversial subject in the literature. Objective: In this context, this study aimed to understand the association between polycystic ovary syndrome and vitamin D deficiency, and how it occurs. Method: It was an integrative review conducted in the PubMed, Scopus, LILACS, and CINAHL databases from August 2016 to January 2017, with a sample of 7 articles analyzed in their entirety. Results: The evidences according to the studies conducted and the conclusions they identified.  Conclusions: It was concluded that we cannot yet assume that vitamin D deficiency contributes to the pathogenesis of PCOS, nor that the syndrome causes vitamin D deficiency, since the studies are controversial and there is a need for research with higher levels of evidence to clarify these doubts.

scholarly journals Assessment of the Relationship between Serum Vitamin D and Osteocalcin Levels with Metabolic Syndrome in Non-Osteoporotic Postmenopausal Women

2019 ◽  
Vol 79 (03) ◽  
pp. 293-299
Author(s):  
Gurhan Guney ◽  
Bilge Sener-Simsek ◽  
Aytekin Tokmak ◽  
Aykan Yucel ◽  
Umran Buyukkagnici ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Vitamin D ◽  
Postmenopausal Women ◽  
Serum Vitamin ◽  
Model Assessment ◽  
Serum Vitamin D ◽  
The Metabolic Syndrome ◽  
The Impact ◽  
The Relationship

Abstract Introduction The aim of this study was to compare serum vitamin D and osteocalcin levels in non-osteoporotic postmenopausal women with and without metabolic syndrome and to analyze the relationship between serum vitamin D and osteocalcin levels and the relationships between these two factors and other clinical/biochemical parameters. Material and Method This cross-sectional study was carried out in 191 postmenopausal non-osteoporotic (T-score > − 2.5) women. Patients were divided into two groups according to the presence or absence of metabolic syndrome. Blood samples were obtained and evaluated for 25-hydroxyvitamin D, osteocalcin, insulin resistance (using a homeostatic model assessment of insulin resistance), glycosylated hemoglobin (HbA1c), calcium, phosphorus, deoxypyridinoline, thyroid-stimulating hormone, lipid profile, fasting insulin, fasting glucose and HbA1c levels. Demographic and laboratory parameters were recorded for each woman. Results Vitamin D was found to be lower in women with metabolic syndrome compared to controls (16.1 ± 11.2 vs. 20.4 ± 13.1 mg/dL; p = 0.013). Similarly, osteocalcin was found to be significantly lower in the metabolic syndrome group compared to the control group (4.2 ± 2.1 vs. 5.5 ± 3.0; p < 0.001). A significant positive correlation was observed between vitamin D and osteocalcin levels (r = 0.198; p = 0.008). There was an inverse correlation between vitamin D and some of the lipid parameters. However, osteocalcin levels were negatively correlated with C-reactive protein, insulin resistance, and HbA1c in both groups (p = 0.003, p = 0.001 and p = 0.048, respectively). Conclusion Vitamin D deficiency is common in postmenopausal women, even in women who are non-osteoporotic. Serum levels of vitamin D are significantly decreased in cases with metabolic syndrome. Vitamin D may directly improve serum lipid profiles and may indirectly decrease insulin resistance and subclinical systemic inflammation through the impact on the metabolic functions of osteocalcin.

scholarly journals Vitamin D supplementation after the menopause

2020 ◽  
Vol 11 ◽  
pp. 204201882093129
Author(s):  
Faustino R. Pérez-López ◽  
Peter Chedraui ◽  
Stefan Pilz
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Postmenopausal Women ◽  
Vitamin D Supplementation ◽  
Lifestyle Changes ◽  
The Body ◽  
Mineral Density ◽  
The Metabolic Syndrome ◽  
Vitamin D Levels

The purpose of this review was to assess recent evidence regarding the effects of low vitamin D levels on some highly prevalent clinical conditions of postmenopausal women. We reviewed and selected recent literature regarding menopause-related conditions associated with vitamin D deficiency and interventions to manage them. Low circulating 25-hydroxyvitamin D (25(OH)D) levels related to menopause are linked to diet, lifestyle, changes in body composition, insulin sensitivity, and reduced physical activity. Vitamin D supplementation increases serum 25(OH)D levels while normalizing parathyroid hormone and bone markers, and in women with serum 25(OH)D levels below 10 ng/ml supplementation may improve bone mineral density. Low vitamin D status has been associated with the metabolic syndrome, high triglyceride levels, and low high-density lipoprotein cholesterol levels. When compared with placebo, vitamin D supplementation may lower the risk of the metabolic syndrome, hypertriglyceridemia, and hyperglycemia. There is an inverse relationship between fat mass and serum 25(OH)D levels and, therefore, the dosage of supplementation should be adjusted according to the body mass index. Although vitamin D supplementation may improve glucose metabolism in prediabetic subjects, data regarding muscle strength are conflictive. There is evidence that vitamin D over-treatment, to reach extremely high circulating 25(OH)D levels, does not result in better clinical outcomes. The identification and treatment of vitamin D deficiency in postmenopausal women may improve their general health and health outcomes. Vitamin D supplementation should preferably be based on the use of either cholecalciferol or calcifediol.

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